iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-061812

UUCD1 version

UUC-MoD-00033

Ensembl Protein ID

ENSMODP00000000339.3

UniProt Accession

H9H5V9; H9H5V9_MONDO

Protein Name

Uncharacterized protein

Gene Name

TLE2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000000281.3	ENSMODT00000000345.3	ENSMODP00000000339.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-17	62.5	577	615

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d  +l++G+ D+t+++WDlr+g++l+
   Q: 577  GHTDGASCIDIsNDgARLWTGGLDNTVRCWDLREGRQLQ 615
           8**********999999*******************998 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MYPQGRPPTG QPFKFSILEI CDRMKEEFQF LQAQYHSLKL ECEKLASEKT EMQRHYVMYY 60
EMSYSLNLEM HKQAEIVKRL STICAKIIPF VKQEHQQQVL QAVERAKQVT TAELNSIIGQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATTGGGGTA GGCACGGGAT AGCAGGACTA GGGAGGCGGG CCACCTTAAG GCCTCGATGC 60
CAGCGGCGTC TCAGATAGAG CTGAACCCCG AGGCGGCTAG AGTGGGACGG ACCGCGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013343	Bos taurus	72.29	0.00e+00	805.00
IUUC-Cja-018857	Callithrix jacchus	70.00	0.00e+00	750.00
IUUC-Hsa-046801	Homo sapiens	72.89	0.00e+00	848.00
IUUC-Laf-053750	Loxodonta africana	70.85	0.00e+00	836.00
IUUC-Mcc-055481	Macaca mulatta	73.32	0.00e+00	857.00
IUUC-Oar-089937	Ovis aries	66.03	0.00e+00	750.00
IUUC-Ptr-090844	Pan troglodytes	70.28	0.00e+00	793.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence