iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090967

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03120310

Gene Name

FZR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000010264.5	ENSPTRT00000018847.5	ENSPTRP00000017443.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-15	55.4	356	387

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH+ +v  la  +d   +v+G++D t++ W++
   Q: 356  GHSYRVLYLAMsPDgEAIVTGAGDETLRFWNV 387
           899999******99999**************7 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MDQDYERRLL RQIVIQNENT MPRVTEMRRT LTPASSPVSS PSKHGDRFIP SRAGANWSVN 60
FHRINENEKS PSQNRKAKDA TSDNGKDGLA YSALLKNELL GAGIEKVQDP QTEDRRLQPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACCAGG ACTATGAGCG GCGCCTGCTT CGCCAGATCG TCATCCAGAA TGAGAACACG 60
ATGCCACGCG TGAGTGCACC CGCCCTGCCC ACCACTGTGG CTCCCCCTCC CCCAGCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0031572--P:G2 DNA damage checkpoint
GO:0070306--P:lens fiber cell differentiation
GO:0090344--P:negative regulation of cell aging
GO:0008284--P:positive regulation of cell proliferation
GO:0045732--P:positive regulation of protein catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002003	Ailuropoda melanoleuca	81.22	8.00e-174	603.00
IUUC-Apl-003212	Anas platyrhynchos	85.03	0.00e+00	651.00
IUUC-Ame-011011	Astyanax mexicanus	79.80	2.00e-162	565.00
IUUC-Bta-012586	Bos taurus	86.29	0.00e+00	656.00
IUUC-Cja-019929	Callithrix jacchus	87.31	0.00e+00	663.00
IUUC-Cfa-020977	Canis familiaris	86.04	0.00e+00	656.00
IUUC-Cpo-021537	Cavia porcellus	86.04	0.00e+00	655.00
IUUC-Csa-023389	Chlorocebus sabaeus	87.56	0.00e+00	665.00
IUUC-Cin-025327	Ciona intestinalis	51.67	1.00e-90	327.00
IUUC-Csv-025921	Ciona savignyi	49.77	1.00e-99	356.00
IUUC-Dre-027470	Danio rerio	77.33	5.00e-158	550.00
IUUC-Dno-029629	Dasypus novemcinctus	76.90	7.00e-159	553.00
IUUC-Dor-030187	Dipodomys ordii	72.84	2.00e-156	545.00
IUUC-Dme-031858	Drosophila melanogaster	58.40	3.00e-106	378.00
IUUC-Ete-032562	Echinops telfairi	69.54	2.00e-141	495.00
IUUC-Eca-034210	Equus caballus	86.29	0.00e+00	658.00
IUUC-Fca-035839	Felis catus	79.44	2.00e-173	601.00
IUUC-Fal-036895	Ficedula albicollis	84.77	0.00e+00	648.00
IUUC-Gmo-039544	Gadus morhua	75.06	2.00e-152	532.00
IUUC-Gga-041025	Gallus gallus	84.77	0.00e+00	648.00
IUUC-Gac-041279	Gasterosteus aculeatus	75.19	9.00e-167	579.00
IUUC-Ggo-045599	Gorilla gorilla	87.31	0.00e+00	628.00
IUUC-Hsa-046695	Homo sapiens	87.56	0.00e+00	664.00
IUUC-Itr-048192	Ictidomys tridecemlineatus	85.53	0.00e+00	651.00
IUUC-Lch-049827	Latimeria chalumnae	82.99	1.00e-172	599.00
IUUC-Loc-052856	Lepisosteus oculatus	80.56	3.00e-166	578.00
IUUC-Laf-054321	Loxodonta africana	64.04	3.00e-145	508.00
IUUC-Mcc-055601	Macaca mulatta	87.56	0.00e+00	665.00
IUUC-Meu-056276	Macropus eugenii	52.56	3.00e-89	322.00
IUUC-Mga-060097	Meleagris gallopavo	79.55	2.00e-173	601.00
IUUC-Mmr-061151	Microcebus murinus	77.35	6.00e-161	560.00
IUUC-Mdo-063062	Monodelphis domestica	84.52	0.00e+00	648.00
IUUC-Mmu-063731	Mus musculus	85.53	0.00e+00	652.00
IUUC-Mpu-066173	Mustela putorius furo	85.79	0.00e+00	655.00
IUUC-Mlu-068030	Myotis lucifugus	86.29	0.00e+00	658.00
IUUC-Nle-070163	Nomascus leucogenys	87.56	0.00e+00	665.00
IUUC-Opr-070974	Ochotona princeps	71.19	1.00e-85	309.00
IUUC-Ont-072507	Oreochromis niloticus	73.48	1.00e-160	559.00
IUUC-Oan-073634	Ornithorhynchus anatinus	78.57	2.00e-102	364.00
IUUC-Ola-087094	Oryzias latipes	76.19	4.00e-145	508.00
IUUC-Oga-088911	Otolemur garnettii	86.80	0.00e+00	659.00
IUUC-Oar-089508	Ovis aries	86.29	0.00e+00	656.00
IUUC-Pan-092147	Papio anubis	87.56	0.00e+00	664.00
IUUC-Psi-093702	Pelodiscus sinensis	84.60	0.00e+00	646.00
IUUC-Pma-094581	Petromyzon marinus	68.73	8.00e-137	480.00
IUUC-Pfo-096309	Poecilia formosa	77.33	6.00e-157	547.00
IUUC-Pab-098762	Pongo abelii	96.43	0.00e+00	786.00
IUUC-Pca-100565	Procavia capensis	77.90	1.00e-155	543.00
IUUC-Pva-102602	Pteropus vampyrus	83.46	0.00e+00	627.00
IUUC-Rno-105028	Rattus norvegicus	85.03	0.00e+00	648.00
IUUC-Sha-107107	Sarcophilus harrisii	68.18	2.00e-142	498.00
IUUC-Sar-112962	Sorex araneus	77.63	5.00e-62	230.00
IUUC-Ssc-116171	Sus scrofa	86.04	0.00e+00	656.00
IUUC-Tgu-116878	Taeniopygia guttata	74.06	3.00e-156	544.00
IUUC-Tru-118222	Takifugu rubripes	76.57	2.00e-155	542.00
IUUC-Tni-119863	Tetraodon nigroviridis	76.83	2.00e-154	538.00
IUUC-Tbe-128056	Tupaia belangeri	70.57	3.00e-98	351.00
IUUC-Ttr-129055	Tursiops truncatus	85.28	0.00e+00	644.00
IUUC-Xtr-132808	Xenopus tropicalis	79.44	4.00e-176	610.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence