iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093763

Ensembl Protein ID

ENSPSIP00000020141.1

UniProt Accession

K7GIN0; K7GIN0_PELSI

Genbank Protein ID

ENSPSIP00000020141

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01002635

Gene Name

UHRF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000017852.1	ENSPSIT00000020236.1	ENSPSIP00000020141.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	8.60e-09	35.5	327	375
ULD/UDP/UBQ/UBQ_PIM	1.30e-14	53.9	1	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
            C+vCg +++ +k  ++C++C+ +fH  Cl+++  ++ p++e+w+Cp+Cr+
   Q: 327  ACHVCGGKQDPDK-QLMCDECDMAFHIYCLNPP-LSSIPDEEDWYCPECRN 375
           59*****999997.566****************.***************85 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgke.fel.evseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           m+++v+t++gke  ++ ++s+ ++veel+ +i +++gv+p++q+L y Gk+++D  +L ++ +  +++v l+v++++
   Q: 1    MWIQVRTMDGKEtHRVdSLSKLTKVEELRLRIHEVFGVEPDRQRLFYRGKQMEDGHSLFDYSVGLNDIVQLLVRQRP 77
           89**********7667789999****************************************************986 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MWIQVRTMDG KETHRVDSLS KLTKVEELRL RIHEVFGVEP DRQRLFYRGK QMEDGHSLFD 60
YSVGLNDIVQ LLVRQRPAML PAISKEKDLE LSDTDSGCGS GQSESDKNSN NGEGAMELEC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCCGCCGCC ATGTGGATCC AGGTGCGCAC CATGGACGGC AAGGAGACCC ACCGGGTGGA 60
CTCGCTCTCC AAGCTCACCA AGGTGGAGGA GCTGCGGCTG CGGATCCACG AGGTGTTCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR015947--PUA-like_domain
IPR014722--Rib_L2_dom2
IPR003105--SRA_YDG
IPR021991--TTD_dom
IPR019956--Ubiquitin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50053--UBIQUITIN_2
PS51015--YDG
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF00628--PHD
PF02182--SAD_SRA
PF12148--TTD
PF00240--ubiquitin

PRINTS

PR00348--UBIQUITIN

SMART

SM00249--PHD
SM00466--SRA
SM00213--UBQ

Gene Ontology

GO:0005720--C:nuclear heterochromatin
GO:0016363--C:nuclear matrix
GO:0005657--C:replication fork
GO:0044729--F:hemi-methylated DNA-binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0010390--P:histone monoubiquitination
GO:0010216--P:maintenance of DNA methylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0051865--P:protein autoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001285	Ailuropoda melanoleuca	76.77	0.00e+00	878.00
IUUC-Apl-003819	Anas platyrhynchos	88.95	0.00e+00	947.00
IUUC-Aca-004970	Anolis carolinensis	82.48	0.00e+00	947.00
IUUC-Bta-012600	Bos taurus	73.91	0.00e+00	823.00
IUUC-Cja-018864	Callithrix jacchus	75.35	0.00e+00	874.00
IUUC-Cfa-020558	Canis familiaris	77.13	0.00e+00	879.00
IUUC-Cpo-022125	Cavia porcellus	74.16	0.00e+00	845.00
IUUC-Csa-023649	Chlorocebus sabaeus	71.45	0.00e+00	814.00
IUUC-Dor-031084	Dipodomys ordii	74.11	0.00e+00	850.00
IUUC-Eca-033266	Equus caballus	76.77	0.00e+00	835.00
IUUC-Eeu-035077	Erinaceus europaeus	81.51	3.00e-142	498.00
IUUC-Fca-035685	Felis catus	66.43	0.00e+00	730.00
IUUC-Gga-040484	Gallus gallus	89.01	0.00e+00	1033.00
IUUC-Ggo-045414	Gorilla gorilla	75.89	0.00e+00	875.00
IUUC-Hsa-046236	Homo sapiens	75.89	0.00e+00	875.00
IUUC-Itr-047867	Ictidomys tridecemlineatus	74.47	0.00e+00	827.00
IUUC-Loc-051806	Lepisosteus oculatus	80.35	0.00e+00	904.00
IUUC-Laf-053671	Loxodonta africana	77.48	0.00e+00	874.00
IUUC-Mcc-055513	Macaca mulatta	75.71	0.00e+00	874.00
IUUC-Mga-059759	Meleagris gallopavo	88.33	0.00e+00	907.00
IUUC-Mdo-061911	Monodelphis domestica	86.90	0.00e+00	997.00
IUUC-Mmu-063738	Mus musculus	69.11	0.00e+00	767.00
IUUC-Mpu-065696	Mustela putorius furo	77.35	0.00e+00	865.00
IUUC-Mlu-067538	Myotis lucifugus	68.72	0.00e+00	783.00
IUUC-Opr-070813	Ochotona princeps	58.20	2.00e-148	519.00
IUUC-Oga-088221	Otolemur garnettii	76.24	0.00e+00	865.00
IUUC-Oar-089604	Ovis aries	70.76	0.00e+00	745.00
IUUC-Ptr-090559	Pan troglodytes	76.06	0.00e+00	875.00
IUUC-Pan-092855	Papio anubis	75.71	0.00e+00	874.00
IUUC-Pab-098243	Pongo abelii	75.53	0.00e+00	858.00
IUUC-Pca-100503	Procavia capensis	77.13	0.00e+00	881.00
IUUC-Rno-105345	Rattus norvegicus	69.15	0.00e+00	775.00
IUUC-Sha-106618	Sarcophilus harrisii	87.61	0.00e+00	996.00
IUUC-Ssc-116081	Sus scrofa	76.28	0.00e+00	861.00
IUUC-Tgu-116538	Taeniopygia guttata	85.11	0.00e+00	978.00
IUUC-Tru-117599	Takifugu rubripes	74.43	0.00e+00	842.00
IUUC-Tni-119843	Tetraodon nigroviridis	75.44	0.00e+00	844.00
IUUC-Ttr-128522	Tursiops truncatus	74.65	0.00e+00	836.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence