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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046616
Ensembl Protein ID ENSP00000384939.3
UniProt Accession B5MBZ0; B5MBZ0_HUMAN
Genbank Protein ID ENSP00000384939
Protein Name Echinoderm microtubule-associated protein-like 4
Genbank Nucleotide ID AC006038
Gene Name EML4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000143924.18 ENST00000318522.9 ENSP00000320663.5
ENSG00000143924.18 ENST00000402711.6 ENSP00000385059.2
ENSG00000143924.18 ENST00000401738.3 ENSP00000384939.3
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
miRecordsRepTarSomamiRmiRcode
RAID2
Protein-protein Interaction
HINTInWeb_IM
Disease-associated Variation
GWASdbGWAS CentralOMIM
Post-translational Modifications (PTMs)
CPLMPHOSIDABioGRID
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.30e-17 64.8 730 765
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH++ +t l++ +d +++ s s+D  i  WD+  g 
   Q: 730  GHSSYITHLDWsPDnKYIMSNSGDYEILYWDIPNGC 765
           8***********998****************87765 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MDGFAGSLDD SISAASTSDV QDRLSALESR VQQQEDEITV LKAALADVLR RLAISEDHVA 60
SVKKSVSSKG QPSPRAVIPM SCITNGSGAN RKPSHTSAVS IAGKETLSSA AKSGTEKKKE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046616|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCGCGGCGC TCGCGGCTGC TGCCTGGGAG GGAGGCCGGG CAGGCGGCTG AGCGGCGCGG 60
CTCTCAACGT GACGGGGAAG TGGTTCGGGC GGCCGCGGCT TACTACCCCA GGGCGAACGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046616|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR005108--HELP
IPR027295--Quinoprotein_ADH-like_fam
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF03451--HELP
PF00400--WD40
SMART

SM00320--WD40
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001465 Ailuropoda melanoleuca 92.34 0.00e+00 1809.00
IUUC-Apl-003728 Anas platyrhynchos 86.79 0.00e+00 1370.00
IUUC-Aca-004921 Anolis carolinensis 74.56 0.00e+00 1443.00
IUUC-Ame-011846 Astyanax mexicanus 77.46 0.00e+00 1425.00
IUUC-Bta-013457 Bos taurus 91.88 0.00e+00 1756.00
IUUC-Cja-019963 Callithrix jacchus 95.07 0.00e+00 1805.00
IUUC-Cfa-020344 Canis familiaris 92.71 0.00e+00 1783.00
IUUC-Cpo-022426 Cavia porcellus 92.57 0.00e+00 1760.00
IUUC-Csa-023822 Chlorocebus sabaeus 96.98 0.00e+00 1861.00
IUUC-Cho-024398 Choloepus hoffmanni 92.57 0.00e+00 729.00
IUUC-Dre-027697 Danio rerio 60.77 0.00e+00 956.00
IUUC-Dno-029822 Dasypus novemcinctus 91.23 0.00e+00 1732.00
IUUC-Dor-030881 Dipodomys ordii 91.52 0.00e+00 900.00
IUUC-Ete-032548 Echinops telfairi 75.82 0.00e+00 1323.00
IUUC-Eca-033255 Equus caballus 91.63 0.00e+00 1820.00
IUUC-Eeu-034609 Erinaceus europaeus 85.98 4.00e-145 509.00
IUUC-Fca-035637 Felis catus 91.94 0.00e+00 1803.00
IUUC-Fal-037030 Ficedula albicollis 85.15 0.00e+00 1617.00
IUUC-Gmo-038662 Gadus morhua 80.48 0.00e+00 1260.00
IUUC-Gga-041202 Gallus gallus 87.54 0.00e+00 1642.00
IUUC-Gac-041394 Gasterosteus aculeatus 73.48 0.00e+00 1336.00
IUUC-Ggo-044734 Gorilla gorilla 98.19 0.00e+00 1844.00
IUUC-Lch-050585 Latimeria chalumnae 77.22 0.00e+00 1459.00
IUUC-Loc-052753 Lepisosteus oculatus 80.68 0.00e+00 1436.00
IUUC-Laf-054189 Loxodonta africana 88.36 0.00e+00 1675.00
IUUC-Mcc-055697 Macaca mulatta 98.29 0.00e+00 1891.00
IUUC-Mmr-060888 Microcebus murinus 92.70 0.00e+00 1735.00
IUUC-Mdo-062025 Monodelphis domestica 83.66 0.00e+00 1504.00
IUUC-Mmu-063591 Mus musculus 88.89 0.00e+00 1738.00
IUUC-Mpu-065718 Mustela putorius furo 92.72 0.00e+00 1817.00
IUUC-Mlu-068068 Myotis lucifugus 91.47 0.00e+00 1753.00
IUUC-Nle-069281 Nomascus leucogenys 97.18 0.00e+00 1787.00
IUUC-Opr-070938 Ochotona princeps 68.44 0.00e+00 1212.00
IUUC-Ont-071488 Oreochromis niloticus 69.94 0.00e+00 1298.00
IUUC-Oan-073561 Ornithorhynchus anatinus 72.62 0.00e+00 998.00
IUUC-Ocu-074399 Oryctolagus cuniculus 94.17 0.00e+00 1807.00
IUUC-Ola-086551 Oryzias latipes 70.73 0.00e+00 1296.00
IUUC-Oga-088783 Otolemur garnettii 93.85 0.00e+00 1816.00
IUUC-Oar-089716 Ovis aries 91.37 0.00e+00 1735.00
IUUC-Ptr-090942 Pan troglodytes 95.77 0.00e+00 1810.00
IUUC-Pan-091831 Papio anubis 97.28 0.00e+00 1889.00
IUUC-Psi-093094 Pelodiscus sinensis 86.83 0.00e+00 1677.00
IUUC-Pfo-097066 Poecilia formosa 68.67 0.00e+00 1253.00
IUUC-Pab-098351 Pongo abelii 98.19 0.00e+00 1842.00
IUUC-Pva-102783 Pteropus vampyrus 81.75 0.00e+00 1531.00
IUUC-Rno-105412 Rattus norvegicus 89.82 0.00e+00 1645.00
IUUC-Sha-106597 Sarcophilus harrisii 86.29 0.00e+00 1669.00
IUUC-Sar-113748 Sorex araneus 76.95 0.00e+00 1323.00
IUUC-Ssc-115740 Sus scrofa 91.38 0.00e+00 1744.00
IUUC-Tgu-116696 Taeniopygia guttata 84.87 0.00e+00 1557.00
IUUC-Tru-118506 Takifugu rubripes 72.72 0.00e+00 1318.00
IUUC-Tsy-119375 Tarsius syrichta 82.55 0.00e+00 1548.00
IUUC-Tni-120392 Tetraodon nigroviridis 68.93 0.00e+00 1202.00
IUUC-Tbe-127468 Tupaia belangeri 84.49 0.00e+00 1571.00
IUUC-Ttr-128746 Tursiops truncatus 87.10 0.00e+00 1750.00
IUUC-Vpa-130697 Vicugna pacos 90.42 0.00e+00 1744.00
IUUC-Xtr-132731 Xenopus tropicalis 78.15 0.00e+00 1556.00
Created Date 25-Jun-2017

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