iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022160

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02019311

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000003324.3	ENSCPOT00000003367.2	ENSCPOP00000003004.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-78	264.5	42	483

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G++N+g tCY+NS+LQ+L+++pe+re+l++  + +l   ++k++       +  +lq+lf++l+  +++a s+ +l+++++++++e  +
   Q: 42   GIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPAELGSLEDKDKPDakvrIIPLQLQRLFAQLLLLDQEAASTADLTDSFGWTSNE--E 128
           9*****************************777776655443222234448899******************************98..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +qi+c+ec+n+s+++e+fldl+++
   Q: 129  MRQHDVQELNRILFSALETSL--------------------------VGTSGHDLINRLYHGTVVNQIVCKECKNISEKQEDFLDLTVA 191
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+d+L +++++ee ++++n y+c +c+++++a+k+ kl+klP++L++ L Rf+f+  ++ r k +++++fpl+++l+p
   Q: 192  VKDVS-----GLEDALwSMYVEEEVFDCDNLYHCGTCDRLVTATKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLKP 275
           *****.....9*****999********************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc+++e ++  ++ Y+L++v++H+G++ +GHY++y+k+                                                   
   Q: 276  FCEQSELNDL-DYVYDLFSVIIHKGGCYGGHYHVYIKDvdhlgnwqfqeefqrepdmslkalqneediddpltvlkallqqeennlipv 363
           ****999997.9***************************************************************************** PP
   S: 302  ...............................................................................ekgk.....W 306
                                                                                          +  +     W
   Q: 364  dqlgqkllkkigiswnkkykkqhgpllkflqvhsqtfllnsdastvslqkkfslqagsgyqsngqqilqmhpskppgsnD--SptcphW 450
           ***********************************************************999999999999988887540..246678* PP
   S: 307  llfdDskVtevkeeevleetg..staYvlfYkr 337
           + ++DskV+++ke++++++ +  ++aY+lfY++
   Q: 451  FDINDSKVQPIKEKDIEQQFQgkESAYMLFYRK 483
           ******************9889*********98 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MFGDLFEEDY SSVSDNQYGK GKKLKTKPLE LPAPREFTNL SGIRNQGGTC YLNSLLQTLH 60
FTPEFREALF SLGPAELGSL EDKDKPDAKV RIIPLQLQRL FAQLLLLDQE AASTADLTDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTGGGG ACCTATTTGA AGAGGATTAT TCCAGTGTGT CAGATAATCA ATATGGAAAA 60
GGGAAGAAAC TAAAGACTAA ACCTTTGGAG CTTCCTGCTC CTAGAGAATT CACCAATTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	79.85	0.00e+00	1855.00
IUUC-Apl-004105	Anas platyrhynchos	61.93	0.00e+00	1507.00
IUUC-Aca-004715	Anolis carolinensis	60.39	0.00e+00	1445.00
IUUC-Ame-011073	Astyanax mexicanus	46.94	0.00e+00	1044.00
IUUC-Bta-012487	Bos taurus	77.79	0.00e+00	1895.00
IUUC-Cja-018937	Callithrix jacchus	79.90	0.00e+00	1967.00
IUUC-Cfa-020645	Canis familiaris	73.56	0.00e+00	1164.00
IUUC-Csa-023078	Chlorocebus sabaeus	79.64	0.00e+00	2006.00
IUUC-Cho-025013	Choloepus hoffmanni	60.53	0.00e+00	762.00
IUUC-Csv-026193	Ciona savignyi	54.17	1.00e-57	215.00
IUUC-Dre-027416	Danio rerio	49.15	0.00e+00	1147.00
IUUC-Dno-029639	Dasypus novemcinctus	74.71	0.00e+00	1560.00
IUUC-Dor-030624	Dipodomys ordii	87.75	4.00e-148	519.00
IUUC-Ete-032626	Echinops telfairi	64.81	0.00e+00	762.00
IUUC-Eca-034208	Equus caballus	79.08	0.00e+00	1966.00
IUUC-Eeu-035340	Erinaceus europaeus	43.86	6.00e-88	319.00
IUUC-Fca-035886	Felis catus	71.18	0.00e+00	743.00
IUUC-Fal-036925	Ficedula albicollis	61.50	0.00e+00	1403.00
IUUC-Gmo-038597	Gadus morhua	45.65	0.00e+00	914.00
IUUC-Gga-041171	Gallus gallus	61.91	0.00e+00	1488.00
IUUC-Gac-041362	Gasterosteus aculeatus	45.60	0.00e+00	964.00
IUUC-Ggo-045069	Gorilla gorilla	78.35	0.00e+00	1793.00
IUUC-Hsa-046715	Homo sapiens	80.21	0.00e+00	1987.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	80.00	0.00e+00	1944.00
IUUC-Lch-050182	Latimeria chalumnae	51.70	0.00e+00	1127.00
IUUC-Loc-052705	Lepisosteus oculatus	53.99	0.00e+00	1264.00
IUUC-Laf-054132	Loxodonta africana	77.71	0.00e+00	1933.00
IUUC-Mcc-055734	Macaca mulatta	79.97	0.00e+00	2003.00
IUUC-Meu-056135	Macropus eugenii	85.41	5.00e-114	405.00
IUUC-Mga-060092	Meleagris gallopavo	62.12	0.00e+00	1474.00
IUUC-Mmr-061546	Microcebus murinus	76.45	0.00e+00	1863.00
IUUC-Mdo-061935	Monodelphis domestica	60.68	0.00e+00	1475.00
IUUC-Mmu-063630	Mus musculus	77.36	0.00e+00	1911.00
IUUC-Mpu-066579	Mustela putorius furo	77.22	0.00e+00	1935.00
IUUC-Mlu-068034	Myotis lucifugus	78.59	0.00e+00	1886.00
IUUC-Nle-069082	Nomascus leucogenys	77.08	0.00e+00	1625.00
IUUC-Opr-070953	Ochotona princeps	68.17	0.00e+00	939.00
IUUC-Ont-072435	Oreochromis niloticus	46.72	0.00e+00	1082.00
IUUC-Oan-073339	Ornithorhynchus anatinus	65.79	0.00e+00	1556.00
IUUC-Ocu-073760	Oryctolagus cuniculus	77.87	0.00e+00	1919.00
IUUC-Ola-087015	Oryzias latipes	45.98	0.00e+00	922.00
IUUC-Oga-088960	Otolemur garnettii	81.02	0.00e+00	1998.00
IUUC-Oar-089853	Ovis aries	77.74	0.00e+00	1916.00
IUUC-Ptr-091093	Pan troglodytes	80.13	0.00e+00	1986.00
IUUC-Pan-091962	Papio anubis	79.02	0.00e+00	1985.00
IUUC-Psi-093691	Pelodiscus sinensis	64.51	0.00e+00	1569.00
IUUC-Pma-094428	Petromyzon marinus	65.83	2.00e-91	328.00
IUUC-Pfo-096983	Poecilia formosa	47.23	0.00e+00	1011.00
IUUC-Pab-097860	Pongo abelii	78.96	0.00e+00	1831.00
IUUC-Pca-100514	Procavia capensis	66.33	1.00e-179	624.00
IUUC-Pva-102771	Pteropus vampyrus	78.20	0.00e+00	1806.00
IUUC-Rno-105405	Rattus norvegicus	77.20	0.00e+00	1872.00
IUUC-Sha-107376	Sarcophilus harrisii	63.00	0.00e+00	1461.00
IUUC-Ssc-115819	Sus scrofa	73.03	0.00e+00	1296.00
IUUC-Tgu-117262	Taeniopygia guttata	60.83	0.00e+00	1470.00
IUUC-Tru-117601	Takifugu rubripes	48.33	0.00e+00	1092.00
IUUC-Tsy-118996	Tarsius syrichta	68.72	0.00e+00	1499.00
IUUC-Tni-120682	Tetraodon nigroviridis	42.53	0.00e+00	853.00
IUUC-Tbe-127616	Tupaia belangeri	60.25	0.00e+00	1162.00
IUUC-Ttr-129075	Tursiops truncatus	75.64	0.00e+00	1762.00
IUUC-Vpa-130108	Vicugna pacos	78.22	0.00e+00	1720.00
IUUC-Xtr-132623	Xenopus tropicalis	52.76	0.00e+00	1195.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence