iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-131773

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

NEDD8-conjugating enzyme UBE2F

Genbank Nucleotide ID

AAMC01007401

Gene Name

ube2f

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000010905.2	ENSXETT00000023831.2	ENSXETP00000023831.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.20e-27	96.5	37	136

Active Site

Position(s)	Description	Evidence
116	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk... 87
           l ke++ele++ p ++++++ d ++l+ +++++  p++++Y+gg F++eie+p+ Y++ PPkvk+lt+i+hPn++e+G++Cls+l+   
   Q: 37   LVKEVAELEANLPCTCKVNFPDPNKLHYFHLTVS-PDESYYQGGRFQFEIEVPDAYNMVPPKVKCLTRIWHPNITETGEICLSLLRehs 124
           679********************99********9.**************************************************7778 PP
   S: 88   .eeekWspalsv 98
            + + W p+ ++
   Q: 125  iDGTGWAPTRTL 136
           88899***9887 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MLTLASKLKR DDGVKGSRTS STTSDSTRRV SVRDRLLVKE VAELEANLPC TCKVNFPDPN 60
KLHYFHLTVS PDESYYQGGR FQFEIEVPDA YNMVPPKVKC LTRIWHPNIT ETGEICLSLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTTACAC TGGCAAGCAA GTTGAAGCGG GACGATGGTG TTAAAGGAAG TAGAACATCT 60
AGCACAACCT CTGATTCAAC ACGCAGAGTG TCTGTTCGTG ACAGATTACT TGTAAAAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001473	Ailuropoda melanoleuca	91.97	9.00e-59	219.00
IUUC-Apl-003569	Anas platyrhynchos	78.79	2.00e-28	116.00
IUUC-Aca-005152	Anolis carolinensis	91.24	9.00e-65	238.00
IUUC-Ame-011839	Astyanax mexicanus	77.37	2.00e-59	221.00
IUUC-Bta-013524	Bos taurus	91.97	3.00e-59	220.00
IUUC-Cel-018579	Caenorhabditis elegans	58.75	9.00e-20	89.40
IUUC-Cja-019211	Callithrix jacchus	89.78	5.00e-61	226.00
IUUC-Cfa-020014	Canis familiaris	91.97	9.00e-59	219.00
IUUC-Cpo-022479	Cavia porcellus	90.51	5.00e-61	226.00
IUUC-Cho-024583	Choloepus hoffmanni	51.82	9.00e-24	102.00
IUUC-Cin-025378	Ciona intestinalis	47.45	2.00e-35	141.00
IUUC-Csv-026195	Ciona savignyi	48.91	4.00e-34	137.00
IUUC-Dre-028671	Danio rerio	79.56	2.00e-59	221.00
IUUC-Dno-029004	Dasypus novemcinctus	91.24	8.00e-66	242.00
IUUC-Dor-030940	Dipodomys ordii	88.32	2.00e-60	224.00
IUUC-Eca-034345	Equus caballus	92.70	3.00e-59	220.00
IUUC-Fca-036125	Felis catus	91.97	7.00e-59	219.00
IUUC-Fal-036808	Ficedula albicollis	90.51	7.00e-67	246.00
IUUC-Gmo-039394	Gadus morhua	90.77	3.00e-33	132.00
IUUC-Gga-041269	Gallus gallus	85.51	3.00e-60	224.00
IUUC-Gac-041480	Gasterosteus aculeatus	81.02	2.00e-58	218.00
IUUC-Ggo-045010	Gorilla gorilla	90.51	2.00e-65	241.00
IUUC-Hsa-046664	Homo sapiens	90.51	2.00e-65	241.00
IUUC-Itr-048522	Ictidomys tridecemlineatus	91.97	1.00e-60	225.00
IUUC-Loc-052137	Lepisosteus oculatus	82.48	4.00e-61	226.00
IUUC-Laf-053694	Loxodonta africana	89.05	1.00e-62	232.00
IUUC-Mcc-055638	Macaca mulatta	90.51	2.00e-65	241.00
IUUC-Meu-056568	Macropus eugenii	85.40	3.00e-60	223.00
IUUC-Mga-059437	Meleagris gallopavo	92.70	1.00e-67	248.00
IUUC-Mmr-061187	Microcebus murinus	91.97	1.00e-63	234.00
IUUC-Mdo-061993	Monodelphis domestica	91.97	3.00e-66	244.00
IUUC-Mmu-064372	Mus musculus	91.97	2.00e-61	228.00
IUUC-Mpu-066423	Mustela putorius furo	91.97	9.00e-59	219.00
IUUC-Mlu-067910	Myotis lucifugus	92.70	3.00e-59	220.00
IUUC-Nle-069032	Nomascus leucogenys	90.51	5.00e-61	226.00
IUUC-Opr-070798	Ochotona princeps	89.05	4.00e-65	240.00
IUUC-Ont-071232	Oreochromis niloticus	80.29	2.00e-58	217.00
IUUC-Oan-072779	Ornithorhynchus anatinus	89.04	7.00e-36	141.00
IUUC-Ocu-074366	Oryctolagus cuniculus	85.40	5.00e-64	236.00
IUUC-Ola-087548	Oryzias latipes	84.29	9.00e-34	134.00
IUUC-Oga-089149	Otolemur garnettii	91.24	3.00e-63	233.00
IUUC-Oar-089662	Ovis aries	91.97	3.00e-59	220.00
IUUC-Ptr-090895	Pan troglodytes	90.51	2.00e-65	241.00
IUUC-Pan-092771	Papio anubis	89.86	5.00e-64	236.00
IUUC-Psi-093582	Pelodiscus sinensis	91.97	9.00e-68	248.00
IUUC-Pma-094321	Petromyzon marinus	78.22	2.00e-47	180.00
IUUC-Pfo-096040	Poecilia formosa	81.75	2.00e-59	221.00
IUUC-Pab-097931	Pongo abelii	90.51	2.00e-65	241.00
IUUC-Pca-100697	Procavia capensis	89.69	1.00e-50	191.00
IUUC-Pva-102609	Pteropus vampyrus	91.24	2.00e-60	224.00
IUUC-Rno-105622	Rattus norvegicus	91.24	2.00e-61	228.00
IUUC-Sha-107614	Sarcophilus harrisii	92.03	5.00e-65	239.00
IUUC-Ssc-115597	Sus scrofa	91.24	9.00e-60	222.00
IUUC-Tgu-117397	Taeniopygia guttata	90.51	9.00e-67	245.00
IUUC-Tru-118496	Takifugu rubripes	76.64	5.00e-57	213.00
IUUC-Tsy-119592	Tarsius syrichta	91.97	1.00e-63	234.00
IUUC-Tni-119759	Tetraodon nigroviridis	78.10	3.00e-57	213.00
IUUC-Tbe-128085	Tupaia belangeri	63.22	2.00e-27	114.00
IUUC-Ttr-129228	Tursiops truncatus	91.24	1.00e-58	218.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence