iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093271

Ensembl Protein ID

ENSPSIP00000006404.1

UniProt Accession

K7FEE4; K7FEE4_PELSI

Genbank Protein ID

ENSPSIP00000006404

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01010865

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000005903.1	ENSPSIT00000006441.1	ENSPSIP00000006404.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.00e-34	115.6	13	50
UBD/Beta-Prp	1.40e-51	175.5	157	372

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 13   GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 50
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 56   tavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee........... 131
            + +fs  g +l+tgs+D++i+ +    +t++ +  l+ h d+v s++fs sgd+++sGs+d t+++w  ++ ++ +            
   Q: 157  LCSSFSVGGTFLATGSTDHVIRMYffGSETPEKIAELESHADKVDSIQFSNSGDRFISGSRDGTAHIWRFQQTEWRSIlldmadrlpgd 245
           4667899999**************99999******************************************999998899********* PP
   S: 132  ....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlq... 210
                ++  +  v+++++++++n +v++ ++  +++W++ tg+ll+++ g htd v  l+   fds  + ++s+++dg + +wd+    
   Q: 246  scseEDKFMKPKVTMIAWNQNDNFVVTAVNNHLLKVWNSYTGQLLHDMVG-HTDEVFVLEthpFDS--RIMLSAGHDGNIFIWDVTkgi 331
           999888888889*************************************9.*********555555..99***************9666 PP
   S: 211  .tgecvrtlnght.dnvksvrfspnderlvsgssDgsiriW 249
            t++  +  +g+    v + +fs+++++++++ s+g + i+
   Q: 332  kTKHYFNMIEGQGhGAVFDCKFSSDGQHFACTDSHGHLLIF 372
           65555555555333566678999999999999999988876 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MYQHIRMHRR ILGHLSAVYC VAFDRTGHRI FTGSDDCLVK IWSTHNGRLL ATLRGHSAEI 60
SDMAVNYENT MIAAGSCDKM IRVWCLRTCA PVAVLQGHTG SITSLQFSPI VKGSMRYMVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTATCAGC ACATAAGGAT GCATAGGCGG ATTCTTGGCC ATCTCTCTGC AGTCTACTGT 60
GTTGCATTTG ATAGGACTGG ACATAGAATA TTTACTGTGA GTTGATGTTG TTAATGTTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	32.16	1.00e-50	195.00
IUUC-Atr-002600	Amborella trichopoda	31.55	1.00e-63	238.00
IUUC-Apl-004083	Anas platyrhynchos	68.81	0.00e+00	2427.00
IUUC-Aca-004348	Anolis carolinensis	78.17	0.00e+00	2078.00
IUUC-Aly-006517	Arabidopsis lyrata	32.08	3.00e-62	233.00
IUUC-Ath-006577	Arabidopsis thaliana	31.60	8.00e-62	232.00
IUUC-Bdi-014797	Brachypodium distachyon	31.75	2.00e-53	204.00
IUUC-Bol-016525	Brassica oleracea	31.60	2.00e-61	231.00
IUUC-Bra-017961	Brassica rapa	32.28	2.00e-67	251.00
IUUC-Cja-019966	Callithrix jacchus	77.18	0.00e+00	2071.00
IUUC-Cpo-021934	Cavia porcellus	75.92	0.00e+00	2057.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	49.57	1.00e-26	114.00
IUUC-Csa-023352	Chlorocebus sabaeus	77.39	0.00e+00	2053.00
IUUC-Cho-024690	Choloepus hoffmanni	87.46	0.00e+00	703.00
IUUC-Fal-037307	Ficedula albicollis	79.96	0.00e+00	2546.00
IUUC-Gga-040865	Gallus gallus	71.86	0.00e+00	2651.00
IUUC-Gma-044324	Glycine max	31.61	1.00e-64	242.00
IUUC-Ggo-045500	Gorilla gorilla	60.73	0.00e+00	2199.00
IUUC-Hsa-046350	Homo sapiens	60.96	0.00e+00	2209.00
IUUC-Hvu-047706	Hordeum vulgare	30.45	7.00e-36	144.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	74.37	0.00e+00	937.00
IUUC-Lch-049662	Latimeria chalumnae	68.19	0.00e+00	1789.00
IUUC-Lpe-051619	Leersia perrieri	31.50	5.00e-59	223.00
IUUC-Loc-052853	Lepisosteus oculatus	65.98	0.00e+00	1663.00
IUUC-Laf-053848	Loxodonta africana	75.99	0.00e+00	2013.00
IUUC-Mcc-054638	Macaca mulatta	60.69	0.00e+00	2200.00
IUUC-Meu-056739	Macropus eugenii	75.60	0.00e+00	900.00
IUUC-Mtr-058094	Medicago truncatula	31.80	2.00e-63	238.00
IUUC-Mga-060165	Meleagris gallopavo	78.99	0.00e+00	2506.00
IUUC-Mmr-061227	Microcebus murinus	61.88	0.00e+00	2210.00
IUUC-Mdo-062074	Monodelphis domestica	77.16	0.00e+00	2046.00
IUUC-Mmu-064075	Mus musculus	62.96	0.00e+00	2098.00
IUUC-Mac-065343	Musa acuminata	31.41	1.00e-63	239.00
IUUC-Ont-072298	Oreochromis niloticus	62.31	0.00e+00	1664.00
IUUC-Oan-072954	Ornithorhynchus anatinus	63.56	0.00e+00	2300.00
IUUC-Ocu-074456	Oryctolagus cuniculus	76.53	0.00e+00	2091.00
IUUC-Oba-075709	Oryza barthii	30.91	1.00e-53	205.00
IUUC-Obr-076619	Oryza brachyantha	30.60	6.00e-59	223.00
IUUC-Ogu-078641	Oryza glumaepatula	36.96	6.00e-28	120.00
IUUC-Olo-080755	Oryza longistaminata	30.92	4.00e-51	197.00
IUUC-Opu-083233	Oryza punctata	30.91	9.00e-54	206.00
IUUC-Oru-085195	Oryza rufipogon	30.91	1.00e-53	205.00
IUUC-Olu-087745	Ostreococcus lucimarinus	29.69	8.00e-54	205.00
IUUC-Oga-087938	Otolemur garnettii	59.66	0.00e+00	1977.00
IUUC-Ptr-091213	Pan troglodytes	60.60	0.00e+00	2187.00
IUUC-Pan-092444	Papio anubis	60.62	0.00e+00	2185.00
IUUC-Ppa-095793	Physcomitrella patens	31.39	2.00e-63	238.00
IUUC-Pfo-097318	Poecilia formosa	63.45	0.00e+00	1617.00
IUUC-Pab-097573	Pongo abelii	75.41	0.00e+00	1981.00
IUUC-Pop-099672	Populus trichocarpa	32.35	5.00e-65	243.00
IUUC-Ppe-101849	Prunus persica	31.30	2.00e-62	235.00
IUUC-Rno-105687	Rattus norvegicus	57.05	0.00e+00	2109.00
IUUC-Sha-106680	Sarcophilus harrisii	62.25	0.00e+00	2251.00
IUUC-Sit-110017	Setaria italica	31.11	5.00e-54	206.00
IUUC-Sly-111348	Solanum lycopersicum	30.89	7.00e-63	236.00
IUUC-Tgu-116513	Taeniopygia guttata	70.72	0.00e+00	2573.00
IUUC-Tsy-118921	Tarsius syrichta	73.22	0.00e+00	1508.00
IUUC-Tca-121098	Theobroma cacao	31.12	4.00e-69	256.00
IUUC-Tae-122854	Triticum aestivum	31.15	2.00e-59	225.00
IUUC-Tbe-127663	Tupaia belangeri	70.87	0.00e+00	1040.00
IUUC-Vpa-130444	Vicugna pacos	82.72	0.00e+00	1058.00
IUUC-Vvi-131362	Vitis vinifera	31.36	2.00e-64	241.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence