iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093798

Ensembl Protein ID

ENSPSIP00000012511.1

UniProt Accession

K7FWV1; K7FWV1_PELSI

Genbank Protein ID

ENSPSIP00000012511

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01019589

Gene Name

AIRE

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000011234.1	ENSPSIT00000012572.1	ENSPSIP00000012511.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.30e-13	50.9	286	330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
            C++C++gge    l++C+ C ++fH aCl ++  +e p+ + w C +C++
   Q: 286  ECAMCRDGGE----LICCDGCPKAFHLACLVPP-LTEIPSGT-WRCISCSA 330
           6*********....*******************.*******6.******86 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

EGGLRQLLKL YRTEISMAVD DVFPLLHGLA DHDVVTEEMF QETMSLKKQE GSHKAFHAML 60
TWLLGQDSAS IQDFWRVLFK DYNLERYSKL QPIRSSFPKD VDLSRQRRGR KPPPSPKALV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGGGGGTC TGCGGCAGCT GCTGAAGCTG TACCGCACAG AGATCTCCAT GGCAGTGGAC 60
GACGTTTTCC CATTGCTTCA TGGACTGGCT GATCATGACG TTGTGACAGA GGAGATGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008087--AIRE
IPR011029--DEATH-like_dom
IPR004865--HSR_dom
IPR000770--SAND_dom
IPR010919--SAND_dom-like
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51414--HSR
PS50864--SAND
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF03172--HSR
PF00628--PHD
PF01342--SAND

PRINTS

PR01711--AIREGULATOR

SMART

SM00249--PHD
SM00258--SAND

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0003682--F:chromatin binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0045182--F:translation regulator activity
GO:0008270--F:zinc ion binding
GO:0002509--P:central tolerance induction to self antigen
GO:0032602--P:chemokine production
GO:0006959--P:humoral immune response
GO:0045060--P:negative thymic T cell selection
GO:0002458--P:peripheral T cell tolerance induction
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:2000410--P:regulation of thymocyte migration
GO:0097536--P:thymus epithelium morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001612	Ailuropoda melanoleuca	51.47	6.00e-119	421.00
IUUC-Aca-004543	Anolis carolinensis	75.81	2.00e-26	109.00
IUUC-Bta-012988	Bos taurus	51.02	1.00e-123	436.00
IUUC-Bdi-014663	Brachypodium distachyon	59.18	6.00e-14	73.60
IUUC-Cja-019486	Callithrix jacchus	43.60	2.00e-53	202.00
IUUC-Cfa-021069	Canis familiaris	49.91	2.00e-112	399.00
IUUC-Cpo-021649	Cavia porcellus	50.00	9.00e-108	383.00
IUUC-Csa-023960	Chlorocebus sabaeus	52.83	2.00e-114	406.00
IUUC-Cne-026966	Cryptococcus neoformans	48.33	2.00e-11	63.90
IUUC-Dre-028583	Danio rerio	44.23	6.00e-68	251.00
IUUC-Dno-029869	Dasypus novemcinctus	42.70	6.00e-84	304.00
IUUC-Dor-030263	Dipodomys ordii	64.84	3.00e-33	135.00
IUUC-Ete-032778	Echinops telfairi	71.96	2.00e-43	170.00
IUUC-Eca-034328	Equus caballus	59.94	1.00e-99	356.00
IUUC-Fca-035400	Felis catus	50.37	2.00e-114	405.00
IUUC-Fal-036644	Ficedula albicollis	52.72	8.00e-98	350.00
IUUC-Ggo-045250	Gorilla gorilla	53.42	1.00e-120	426.00
IUUC-Hsa-046603	Homo sapiens	51.90	1.00e-120	426.00
IUUC-Hvu-047073	Hordeum vulgare	61.70	4.00e-14	73.90
IUUC-Itr-048977	Ictidomys tridecemlineatus	48.74	4.00e-117	414.00
IUUC-Lch-050310	Latimeria chalumnae	47.81	6.00e-127	447.00
IUUC-Loc-052508	Lepisosteus oculatus	48.67	2.00e-90	326.00
IUUC-Lma-053053	Leptosphaeria maculans	37.50	1.00e-12	68.90
IUUC-Laf-054028	Loxodonta africana	56.29	1.00e-93	336.00
IUUC-Mcc-054935	Macaca mulatta	51.13	1.00e-120	426.00
IUUC-Mga-059318	Meleagris gallopavo	42.52	2.00e-64	239.00
IUUC-Mmr-061557	Microcebus murinus	46.27	6.00e-96	344.00
IUUC-Mdo-062475	Monodelphis domestica	56.05	8.00e-148	516.00
IUUC-Mmu-063994	Mus musculus	51.21	1.00e-132	466.00
IUUC-Mpu-066347	Mustela putorius furo	49.46	4.00e-128	451.00
IUUC-Mlu-068239	Myotis lucifugus	44.92	1.00e-61	229.00
IUUC-Nle-069544	Nomascus leucogenys	74.58	1.00e-22	99.80
IUUC-Opr-071199	Ochotona princeps	55.79	3.00e-54	206.00
IUUC-Ont-072571	Oreochromis niloticus	32.84	2.00e-62	233.00
IUUC-Oan-073739	Ornithorhynchus anatinus	61.27	3.00e-174	604.00
IUUC-Ogl-077865	Oryza glaberrima	46.27	7.00e-14	72.80
IUUC-Olo-080499	Oryza longistaminata	59.57	2.00e-13	71.60
IUUC-Opu-083209	Oryza punctata	59.57	2.00e-13	71.60
IUUC-Ola-086528	Oryzias latipes	35.55	3.00e-48	185.00
IUUC-Oga-088353	Otolemur garnettii	53.47	3.00e-126	444.00
IUUC-Oar-090065	Ovis aries	54.95	6.00e-107	380.00
IUUC-Ptr-091347	Pan troglodytes	52.46	3.00e-115	408.00
IUUC-Pan-092423	Papio anubis	50.89	3.00e-119	421.00
IUUC-Pfo-096145	Poecilia formosa	34.59	7.00e-24	105.00
IUUC-Pab-098369	Pongo abelii	59.08	7.00e-87	313.00
IUUC-Pca-100537	Procavia capensis	48.13	1.00e-111	396.00
IUUC-Ppe-101215	Prunus persica	45.33	2.00e-14	74.30
IUUC-Pva-102639	Pteropus vampyrus	51.12	1.00e-105	376.00
IUUC-Pte-104185	Pyrenophora teres	46.00	5.00e-12	67.40
IUUC-Pyt-104775	Pyrenophora triticirepentis	43.64	2.00e-12	68.20
IUUC-Rno-105285	Rattus norvegicus	53.18	2.00e-136	478.00
IUUC-Sha-107159	Sarcophilus harrisii	51.85	4.00e-141	494.00
IUUC-Sit-110355	Setaria italica	59.18	4.00e-13	70.90
IUUC-Sbi-113930	Sorghum bicolor	57.14	1.00e-12	68.90
IUUC-Ssc-115773	Sus scrofa	48.91	1.00e-118	420.00
IUUC-Tgu-116922	Taeniopygia guttata	51.51	1.00e-88	319.00
IUUC-Tru-118263	Takifugu rubripes	36.69	6.00e-76	278.00
IUUC-Tsy-119270	Tarsius syrichta	51.01	2.00e-58	219.00
IUUC-Tni-120138	Tetraodon nigroviridis	34.51	7.00e-70	258.00
IUUC-Tca-121757	Theobroma cacao	54.72	8.00e-14	73.20
IUUC-Tae-124715	Triticum aestivum	61.70	4.00e-14	74.30
IUUC-Tbe-128077	Tupaia belangeri	46.73	3.00e-111	395.00
IUUC-Ttr-128781	Tursiops truncatus	56.91	3.00e-47	182.00
IUUC-Xma-133054	Xiphophorus maculatus	32.21	2.00e-69	256.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence