iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052119

Ensembl Protein ID

ENSLOCP00000002208.1

UniProt Accession

W5M1F0; W5M1F0_LEPOC

Genbank Protein ID

ENSLOCP00000002208

Protein Name

Protein HIRA

Genbank Nucleotide ID

AHAT01028751

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000001895.1	ENSLOCT00000002213.1	ENSLOCP00000002208.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-20	73.0	69	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H + v+c+++ ++  +l+sG+dD+ ++vW 
   Q: 69   HLACVNCVRWsNNgLYLASGGDDKLVMVWK 98
           8899******977799*************7 PP

Organism

Lepisosteus oculatus

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MKLLKPTWVS HNGKPIFSID IHPEGTKFAT GGQGEDSGKV VIWNMAPVLR EEDEKNETVP 60
KMLCQMDNHL ACVNCVRWSN NGLYLASGGD DKLVMVWKRA AYIGPSTVFG SSSKLANVEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTCGCTCGT AGGGCCACGC AATTAAAAAA AAAAAGCTCG CACGGGCCTG ACCTCTCTCA 60
GGGCATGTGT TTCCAGGGGA ACTTTAGGAA AGGTCGGATA CTTCCTGTGT TGCTGCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR019015--HIRA_B_motif
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF09453--HIRA_B
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	34.27	3.00e-85	310.00
IUUC-Aml-001723	Ailuropoda melanoleuca	71.70	0.00e+00	1328.00
IUUC-Atr-003132	Amborella trichopoda	36.10	5.00e-88	319.00
IUUC-Apl-003197	Anas platyrhynchos	73.99	0.00e+00	1388.00
IUUC-Aca-004733	Anolis carolinensis	71.79	0.00e+00	1368.00
IUUC-Aly-005446	Arabidopsis lyrata	35.46	3.00e-81	296.00
IUUC-Ath-007627	Arabidopsis thaliana	36.78	5.00e-85	309.00
IUUC-Ago-007766	Ashbya gossypii	32.14	7.00e-59	222.00
IUUC-Acl-008104	Aspergillus clavatus	32.14	3.00e-62	234.00
IUUC-Afl-008591	Aspergillus flavus	31.18	3.00e-61	230.00
IUUC-Afu-008781	Aspergillus fumigatus	33.25	1.00e-56	215.00
IUUC-Ani-009272	Aspergillus nidulans	30.90	1.00e-52	201.00
IUUC-Ang-009655	Aspergillus niger	32.54	9.00e-63	235.00
IUUC-Aor-010119	Aspergillus oryzae	29.25	2.00e-61	231.00
IUUC-Ate-010530	Aspergillus terreus	26.78	8.00e-55	209.00
IUUC-Ame-011147	Astyanax mexicanus	90.10	2.00e-54	202.00
IUUC-Bgr-012237	Blumeria graminis	32.83	1.00e-61	231.00
IUUC-Bta-013320	Bos taurus	70.65	0.00e+00	1324.00
IUUC-Bci-013795	Botrytis cinerea	33.25	2.00e-67	250.00
IUUC-Bdi-014075	Brachypodium distachyon	36.22	1.00e-88	321.00
IUUC-Bol-016440	Brassica oleracea	36.67	1.00e-86	315.00
IUUC-Bra-016651	Brassica rapa	36.67	6.00e-87	315.00
IUUC-Cel-018692	Caenorhabditis elegans	38.89	2.00e-76	280.00
IUUC-Cja-018987	Callithrix jacchus	71.44	0.00e+00	1249.00
IUUC-Cfa-020132	Canis familiaris	71.34	0.00e+00	1327.00
IUUC-Cpo-021484	Cavia porcellus	72.86	0.00e+00	1356.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	35.34	5.00e-62	233.00
IUUC-Csa-023081	Chlorocebus sabaeus	72.55	0.00e+00	1346.00
IUUC-Cin-025182	Ciona intestinalis	50.71	6.00e-159	555.00
IUUC-Csv-026154	Ciona savignyi	55.17	2.00e-154	539.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	33.26	4.00e-69	256.00
IUUC-Cne-026891	Cryptococcus neoformans	40.81	5.00e-83	302.00
IUUC-Cme-027349	Cyanidioschyzon merolae	30.78	2.00e-51	197.00
IUUC-Dre-027655	Danio rerio	78.34	0.00e+00	1494.00
IUUC-Dno-029557	Dasypus novemcinctus	65.39	0.00e+00	868.00
IUUC-Dor-030687	Dipodomys ordii	73.15	0.00e+00	681.00
IUUC-Dse-031334	Dothistroma septosporum	31.37	2.00e-65	244.00
IUUC-Dme-031746	Drosophila melanogaster	55.01	2.00e-159	556.00
IUUC-Ete-032384	Echinops telfairi	68.23	0.00e+00	1231.00
IUUC-Eca-033430	Equus caballus	71.70	0.00e+00	1312.00
IUUC-Fca-036121	Felis catus	71.27	0.00e+00	1331.00
IUUC-Fal-036817	Ficedula albicollis	73.48	0.00e+00	1386.00
IUUC-Fox-037906	Fusarium oxysporum	32.57	8.00e-67	248.00
IUUC-Fso-038409	Fusarium solani	33.03	2.00e-66	247.00
IUUC-Gmo-039151	Gadus morhua	65.69	0.00e+00	1261.00
IUUC-Ggr-040016	Gaeumannomyces graminis	33.18	7.00e-70	259.00
IUUC-Gga-040936	Gallus gallus	74.45	0.00e+00	1456.00
IUUC-Gac-041405	Gasterosteus aculeatus	68.86	0.00e+00	1266.00
IUUC-Gma-044252	Glycine max	35.32	8.00e-87	315.00
IUUC-Ggo-045430	Gorilla gorilla	72.27	0.00e+00	1338.00
IUUC-Hsa-046442	Homo sapiens	72.44	0.00e+00	1347.00
IUUC-Hvu-047587	Hordeum vulgare	34.87	4.00e-76	280.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	90.67	2.00e-163	567.00
IUUC-Kpa-049145	Komagataella pastoris	30.44	2.00e-59	224.00
IUUC-Lch-050474	Latimeria chalumnae	86.24	0.00e+00	834.00
IUUC-Lpe-051209	Leersia perrieri	35.85	8.00e-83	301.00
IUUC-Lma-053237	Leptosphaeria maculans	35.03	5.00e-66	246.00
IUUC-Laf-053718	Loxodonta africana	73.54	0.00e+00	1355.00
IUUC-Mcc-055621	Macaca mulatta	71.73	0.00e+00	1256.00
IUUC-Meu-055914	Macropus eugenii	60.29	0.00e+00	658.00
IUUC-Mor-057090	Magnaporthe oryzae	31.67	8.00e-68	252.00
IUUC-Mpo-057364	Magnaporthe poae	33.41	3.00e-71	263.00
IUUC-Mtr-057744	Medicago truncatula	36.49	2.00e-87	317.00
IUUC-Mla-058914	Melampsora laricipopulina	36.44	1.00e-85	311.00
IUUC-Mga-060181	Meleagris gallopavo	72.78	0.00e+00	1402.00
IUUC-Mvi-060432	Microbotryum violaceum	37.08	7.00e-74	272.00
IUUC-Mmr-060871	Microcebus murinus	72.65	0.00e+00	1370.00
IUUC-Mdo-062301	Monodelphis domestica	71.66	0.00e+00	1367.00
IUUC-Mmu-063888	Mus musculus	72.41	0.00e+00	1349.00
IUUC-Mac-065137	Musa acuminata	37.10	1.00e-86	314.00
IUUC-Mpu-066732	Mustela putorius furo	72.13	0.00e+00	1342.00
IUUC-Mlu-067542	Myotis lucifugus	70.80	0.00e+00	1324.00
IUUC-Nfi-068396	Neosartorya fischeri	33.25	1.00e-56	215.00
IUUC-Ncr-068842	Neurospora crassa	32.28	5.00e-70	259.00
IUUC-Nle-070156	Nomascus leucogenys	73.05	0.00e+00	1350.00
IUUC-Opr-070808	Ochotona princeps	69.83	0.00e+00	1073.00
IUUC-Ont-072105	Oreochromis niloticus	77.07	0.00e+00	1475.00
IUUC-Ocu-074962	Oryctolagus cuniculus	71.91	0.00e+00	1336.00
IUUC-Oba-075178	Oryza barthii	35.55	1.00e-88	321.00
IUUC-Obr-076399	Oryza brachyantha	36.75	1.00e-89	324.00
IUUC-Ogu-078797	Oryza glumaepatula	35.55	1.00e-88	321.00
IUUC-Oin-080085	Oryza indica	33.96	1.00e-75	278.00
IUUC-Olo-081048	Oryza longistaminata	39.94	8.00e-64	239.00
IUUC-Ome-081324	Oryza meridionalis	36.70	1.00e-88	321.00
IUUC-Oni-082548	Oryza nivara	35.55	1.00e-88	321.00
IUUC-Opu-084008	Oryza punctata	40.97	4.00e-88	319.00
IUUC-Oru-084339	Oryza rufipogon	35.55	1.00e-88	321.00
IUUC-Osa-085782	Oryza sativa	35.55	1.00e-88	321.00
IUUC-Ola-087302	Oryzias latipes	75.57	0.00e+00	895.00
IUUC-Olu-087611	Ostreococcus lucimarinus	35.27	6.00e-87	315.00
IUUC-Oga-087935	Otolemur garnettii	71.83	0.00e+00	1308.00
IUUC-Oar-089229	Ovis aries	55.42	0.00e+00	865.00
IUUC-Ptr-090715	Pan troglodytes	72.44	0.00e+00	1346.00
IUUC-Pan-092318	Papio anubis	72.27	0.00e+00	1316.00
IUUC-Psi-094053	Pelodiscus sinensis	73.30	0.00e+00	1388.00
IUUC-Pno-094985	Phaeosphaeria nodorum	31.95	5.00e-58	219.00
IUUC-Ppa-095819	Physcomitrella patens	34.84	1.00e-85	311.00
IUUC-Pfo-096857	Poecilia formosa	74.48	0.00e+00	1399.00
IUUC-Pab-098047	Pongo abelii	72.44	0.00e+00	1344.00
IUUC-Pop-099587	Populus trichocarpa	36.64	2.00e-87	317.00
IUUC-Pca-100558	Procavia capensis	65.99	2.00e-134	473.00
IUUC-Ppe-101261	Prunus persica	36.46	2.00e-87	317.00
IUUC-Pva-102683	Pteropus vampyrus	71.76	0.00e+00	1360.00
IUUC-Pgr-103660	Puccinia graminis	33.95	1.00e-78	287.00
IUUC-Ptt-103900	Puccinia triticina	41.99	1.00e-79	291.00
IUUC-Pte-104209	Pyrenophora teres	32.15	1.00e-64	241.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	34.77	6.00e-64	239.00
IUUC-Rno-105566	Rattus norvegicus	72.61	0.00e+00	1361.00
IUUC-Sce-106291	Saccharomyces cerevisiae	32.29	1.00e-62	234.00
IUUC-Sha-107514	Sarcophilus harrisii	68.00	0.00e+00	1231.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	35.96	2.00e-80	294.00
IUUC-Spo-108162	Schizosaccharomyces pombe	39.15	5.00e-77	282.00
IUUC-Smo-109186	Selaginella moellendorffii	36.22	8.00e-88	318.00
IUUC-Sit-110730	Setaria italica	36.42	4.00e-89	322.00
IUUC-Sly-111547	Solanum lycopersicum	36.20	4.00e-88	319.00
IUUC-Stu-112705	Solanum tuberosum	36.14	4.00e-88	320.00
IUUC-Sar-113222	Sorex araneus	66.80	0.00e+00	1219.00
IUUC-Sbi-114272	Sorghum bicolor	36.44	3.00e-91	330.00
IUUC-Sre-115061	Sporisorium reilianum	33.82	1.00e-76	281.00
IUUC-Ssc-116364	Sus scrofa	71.02	0.00e+00	1356.00
IUUC-Tgu-116645	Taeniopygia guttata	73.88	0.00e+00	1405.00
IUUC-Tru-117590	Takifugu rubripes	73.81	0.00e+00	1390.00
IUUC-Tsy-119212	Tarsius syrichta	72.53	0.00e+00	801.00
IUUC-Tni-119915	Tetraodon nigroviridis	74.43	0.00e+00	1444.00
IUUC-Tca-121765	Theobroma cacao	34.22	2.00e-88	320.00
IUUC-Tre-121887	Trichoderma reesei	32.13	6.00e-60	226.00
IUUC-Tvi-122262	Trichoderma virens	32.13	2.00e-60	227.00
IUUC-Tae-124148	Triticum aestivum	44.26	4.00e-38	153.00
IUUC-Tur-126483	Triticum urartu	36.51	2.00e-89	323.00
IUUC-Tme-127202	Tuber melanosporum	30.32	1.00e-56	214.00
IUUC-Tbe-127350	Tupaia belangeri	72.20	3.00e-164	572.00
IUUC-Ttr-129077	Tursiops truncatus	68.02	0.00e+00	1287.00
IUUC-Uma-129465	Ustilago maydis	34.38	4.00e-78	286.00
IUUC-Vda-129844	Verticillium dahliae	33.41	3.00e-68	253.00
IUUC-Vvi-131397	Vitis vinifera	34.90	9.00e-89	322.00
IUUC-Xtr-132057	Xenopus tropicalis	69.39	0.00e+00	1315.00
IUUC-Xma-134139	Xiphophorus maculatus	75.29	0.00e+00	919.00
IUUC-Yli-134424	Yarrowia lipolytica	31.19	1.00e-63	238.00
IUUC-Zma-135506	Zea mays	34.94	2.00e-90	327.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence