iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	60.00	5.00e-09	58.90	IUUC-Sce-106309

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MASSSTETQL QRIIRDLQDA VTELSNEFKE GGEPITDDST SLHKFSYKLE YLLQFDQKEK 60
ASLLGSKKDY WDYFCACLAK VKGANDGIRF VRSISELRTS LGKGRAFIRY SLVHQRLADT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACCTGTGAA GCATACCGGG AGTCGTAGTC CGCGCGCGCT CTGGGTGTAC TGGGCGCTTC 60
ATGGCCGCCG GCACTGCGCT TGCCTACTCT TCCGCTCGGC CCTAGAAAGT TTCGTTTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR009038--GOLD_dom
IPR004012--Run_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50866--GOLD
PS50826--RUN
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF02759--RUN

SMART

SM00064--FYVE

Gene Ontology

GO:0005776--C:autophagosome
GO:0005794--C:Golgi apparatus
GO:0016021--C:integral component of membrane
GO:0005770--C:late endosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0044183--F:protein binding involved in protein folding
GO:0051082--F:unfolded protein binding
GO:0006458--P:'de novo' protein folding
GO:0061077--P:chaperone-mediated protein folding
GO:0072383--P:plus-end-directed vesicle transport along microtubule
GO:1901098--P:positive regulation of autophagosome maturation

KEGG

rno:301085

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001622	Ailuropoda melanoleuca	70.80	0.00e+00	1738.00
IUUC-Apl-004173	Anas platyrhynchos	38.88	2.00e-137	483.00
IUUC-Ame-010798	Astyanax mexicanus	48.83	4.00e-111	394.00
IUUC-Bta-012394	Bos taurus	72.33	0.00e+00	1771.00
IUUC-Cja-019711	Callithrix jacchus	76.52	0.00e+00	1912.00
IUUC-Cfa-020392	Canis familiaris	70.47	0.00e+00	1767.00
IUUC-Cpo-021456	Cavia porcellus	71.67	0.00e+00	1809.00
IUUC-Csa-023192	Chlorocebus sabaeus	76.30	0.00e+00	1898.00
IUUC-Dre-027779	Danio rerio	41.41	1.00e-153	537.00
IUUC-Dno-029277	Dasypus novemcinctus	67.77	0.00e+00	1238.00
IUUC-Eca-033806	Equus caballus	77.10	0.00e+00	1925.00
IUUC-Fca-035563	Felis catus	70.40	0.00e+00	1104.00
IUUC-Fal-036657	Ficedula albicollis	49.47	0.00e+00	1296.00
IUUC-Gmo-038911	Gadus morhua	38.59	8.00e-173	601.00
IUUC-Gga-041069	Gallus gallus	51.77	0.00e+00	1362.00
IUUC-Gac-042183	Gasterosteus aculeatus	38.70	2.00e-142	501.00
IUUC-Ggo-045276	Gorilla gorilla	77.73	0.00e+00	1917.00
IUUC-Hsa-046982	Homo sapiens	77.12	0.00e+00	1885.00
IUUC-Itr-048929	Ictidomys tridecemlineatus	77.16	0.00e+00	1893.00
IUUC-Kpa-049401	Komagataella pastoris	43.18	6.00e-09	53.90
IUUC-Lch-049451	Latimeria chalumnae	43.35	0.00e+00	934.00
IUUC-Loc-052441	Lepisosteus oculatus	42.96	0.00e+00	1017.00
IUUC-Laf-053370	Loxodonta africana	70.35	0.00e+00	1463.00
IUUC-Mcc-054975	Macaca mulatta	76.44	0.00e+00	1943.00
IUUC-Meu-056668	Macropus eugenii	54.77	2.00e-177	616.00
IUUC-Mmr-061339	Microcebus murinus	76.57	0.00e+00	1887.00
IUUC-Mdo-063054	Monodelphis domestica	57.31	0.00e+00	1456.00
IUUC-Mlu-067157	Myotis lucifugus	71.92	0.00e+00	1761.00
IUUC-Nle-069695	Nomascus leucogenys	76.78	0.00e+00	1873.00
IUUC-Ont-072336	Oreochromis niloticus	36.35	2.00e-159	556.00
IUUC-Oan-073536	Ornithorhynchus anatinus	58.84	0.00e+00	1598.00
IUUC-Ola-086470	Oryzias latipes	43.03	3.00e-95	343.00
IUUC-Oga-088658	Otolemur garnettii	75.52	0.00e+00	1944.00
IUUC-Oar-089316	Ovis aries	77.08	0.00e+00	893.00
IUUC-Ptr-091653	Pan troglodytes	77.39	0.00e+00	1891.00
IUUC-Pan-092033	Papio anubis	75.66	0.00e+00	1833.00
IUUC-Psi-093520	Pelodiscus sinensis	61.45	0.00e+00	637.00
IUUC-Pfo-096903	Poecilia formosa	39.82	0.00e+00	835.00
IUUC-Pab-098777	Pongo abelii	77.66	0.00e+00	1928.00
IUUC-Pva-102241	Pteropus vampyrus	74.36	0.00e+00	1809.00
IUUC-Sce-106309	Saccharomyces cerevisiae	60.00	2.00e-10	59.30
IUUC-Sha-106591	Sarcophilus harrisii	60.08	0.00e+00	1459.00
IUUC-Spo-108288	Schizosaccharomyces pombe	52.63	8.00e-11	60.80
IUUC-Ssl-108651	Sclerotinia sclerotiorum	34.78	3.80e-01	30.80
IUUC-Ssc-115324	Sus scrofa	71.77	0.00e+00	1539.00
IUUC-Tgu-116887	Taeniopygia guttata	54.59	0.00e+00	1354.00
IUUC-Tru-118394	Takifugu rubripes	31.32	9.00e-75	275.00
IUUC-Tsy-119577	Tarsius syrichta	74.00	0.00e+00	1814.00
IUUC-Tni-119998	Tetraodon nigroviridis	39.06	3.00e-152	533.00
IUUC-Tbe-127875	Tupaia belangeri	35.71	5.00e-13	70.90
IUUC-Ttr-128386	Tursiops truncatus	75.46	0.00e+00	836.00
IUUC-Vpa-130696	Vicugna pacos	35.71	5.00e-13	70.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence