iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020341

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03012241

Gene Name

KLHL18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000013286.2	ENSCAFT00000021140.2	ENSCAFP00000019632.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.40e-20	73.0	52	117
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.60e-10	39.4	151	181

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l++g+ +f+ah+ivLaas ++F+a+f++++ e k ++++++++++p++++al++F Y g l +
   Q: 52   CDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECK-QDEIVMQGMDPSALEALINFAYNGHLAI 117
           9*************************************.************************9875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Nclg+++fA+++ c  L+daa++fi++hF
   Q: 151  PKNCLGVRQFAETMMCAVLYDAANSFIHQHF 181
           68***************************** PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

SRPATPAQSR RPGKMVEDGA EELEDLVHFS VSELPSRGYG VMEEIRRQGK LCDVTLKIGD 60
HKFSAHRIVL AASIPYFHAM FTNDMMECKQ DEIVMQGMDP SALEALINFA YNGHLAIDQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCCGGCCGG CCACGCCTGC GCAGTCGCGG CGGCCGGGGA AGATGGTGGA GGACGGCGCG 60
GAGGAGCTGG AGGACCTGGT GCACTTCTCC GTGTCCGAGT TGCCTAGTCG GGGCTACGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001536	Ailuropoda melanoleuca	97.96	0.00e+00	1202.00
IUUC-Apl-003270	Anas platyrhynchos	90.58	0.00e+00	1004.00
IUUC-Aca-005395	Anolis carolinensis	91.15	0.00e+00	1085.00
IUUC-Bta-013481	Bos taurus	96.89	0.00e+00	1173.00
IUUC-Cel-018622	Caenorhabditis elegans	44.66	5.00e-141	494.00
IUUC-Cja-019847	Callithrix jacchus	97.56	0.00e+00	1165.00
IUUC-Cpo-021613	Cavia porcellus	95.16	0.00e+00	1068.00
IUUC-Csa-023611	Chlorocebus sabaeus	97.21	0.00e+00	1163.00
IUUC-Cho-024605	Choloepus hoffmanni	80.94	1.00e-136	479.00
IUUC-Cin-025289	Ciona intestinalis	54.34	0.00e+00	644.00
IUUC-Dre-028248	Danio rerio	83.89	0.00e+00	1018.00
IUUC-Dno-029609	Dasypus novemcinctus	96.53	0.00e+00	1166.00
IUUC-Dor-030541	Dipodomys ordii	96.48	2.00e-149	521.00
IUUC-Dme-032107	Drosophila melanogaster	55.32	0.00e+00	660.00
IUUC-Eca-033507	Equus caballus	97.93	0.00e+00	1092.00
IUUC-Eeu-034750	Erinaceus europaeus	89.45	0.00e+00	976.00
IUUC-Fca-035731	Felis catus	99.13	0.00e+00	1188.00
IUUC-Fal-036959	Ficedula albicollis	90.78	0.00e+00	1053.00
IUUC-Gga-040166	Gallus gallus	93.12	0.00e+00	1106.00
IUUC-Ggo-044853	Gorilla gorilla	97.21	0.00e+00	1163.00
IUUC-Hsa-046437	Homo sapiens	96.86	0.00e+00	1155.00
IUUC-Itr-048529	Ictidomys tridecemlineatus	95.72	0.00e+00	1052.00
IUUC-Lch-050195	Latimeria chalumnae	78.39	0.00e+00	915.00
IUUC-Loc-051787	Lepisosteus oculatus	85.86	0.00e+00	991.00
IUUC-Laf-053489	Loxodonta africana	97.57	0.00e+00	1176.00
IUUC-Mcc-055250	Macaca mulatta	96.37	0.00e+00	1158.00
IUUC-Meu-056871	Macropus eugenii	88.77	0.00e+00	1036.00
IUUC-Mtr-058180	Medicago truncatula	33.19	8.00e-36	145.00
IUUC-Mga-059425	Meleagris gallopavo	92.77	0.00e+00	1098.00
IUUC-Mmr-061394	Microcebus murinus	97.24	0.00e+00	1171.00
IUUC-Mdo-062285	Monodelphis domestica	95.37	0.00e+00	1125.00
IUUC-Mmu-063975	Mus musculus	97.24	0.00e+00	1172.00
IUUC-Mpu-066369	Mustela putorius furo	98.61	0.00e+00	1182.00
IUUC-Mlu-067832	Myotis lucifugus	94.77	0.00e+00	1065.00
IUUC-Nle-069338	Nomascus leucogenys	90.00	0.00e+00	1071.00
IUUC-Opr-071035	Ochotona princeps	84.93	0.00e+00	918.00
IUUC-Ont-071440	Oreochromis niloticus	83.19	0.00e+00	978.00
IUUC-Ola-087275	Oryzias latipes	81.48	0.00e+00	976.00
IUUC-Oga-087921	Otolemur garnettii	97.96	0.00e+00	1203.00
IUUC-Oar-089968	Ovis aries	89.46	0.00e+00	1041.00
IUUC-Ptr-091272	Pan troglodytes	97.21	0.00e+00	1163.00
IUUC-Pan-092629	Papio anubis	97.04	0.00e+00	1159.00
IUUC-Psi-093456	Pelodiscus sinensis	93.65	0.00e+00	991.00
IUUC-Pma-094509	Petromyzon marinus	69.20	0.00e+00	800.00
IUUC-Pfo-096450	Poecilia formosa	79.65	0.00e+00	965.00
IUUC-Pab-097917	Pongo abelii	96.43	0.00e+00	1179.00
IUUC-Pop-099153	Populus trichocarpa	33.19	3.00e-35	143.00
IUUC-Pca-100330	Procavia capensis	97.32	8.00e-176	610.00
IUUC-Pva-103189	Pteropus vampyrus	98.26	0.00e+00	1178.00
IUUC-Pyt-104758	Pyrenophora triticirepentis	34.94	5.00e-07	48.10
IUUC-Sha-107283	Sarcophilus harrisii	95.21	0.00e+00	1090.00
IUUC-Sar-112989	Sorex araneus	96.80	0.00e+00	1077.00
IUUC-Tgu-117146	Taeniopygia guttata	82.12	0.00e+00	917.00
IUUC-Tru-118132	Takifugu rubripes	82.76	0.00e+00	957.00
IUUC-Tsy-119058	Tarsius syrichta	80.27	2.00e-136	479.00
IUUC-Tni-120892	Tetraodon nigroviridis	80.00	0.00e+00	958.00
IUUC-Tbe-127347	Tupaia belangeri	94.95	0.00e+00	1134.00
IUUC-Ttr-128343	Tursiops truncatus	75.52	0.00e+00	780.00
IUUC-Vpa-130796	Vicugna pacos	85.02	0.00e+00	981.00
IUUC-Xtr-132077	Xenopus tropicalis	83.19	0.00e+00	946.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence