iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-097184

Ensembl Protein ID

ENSPFOP00000004817.1

UniProt Accession

A0A087XGB4; A0A087XGB4_POEFO

Genbank Protein ID

ENSPFOP00000004817

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01012766

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000004588.2	ENSPFOT00000004826.2	ENSPFOP00000004817.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.20e-220	732.6	452	930

Active Site

Position(s)	Description	Evidence
632	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkeln 85
           YD+Qi+++G++ q++l  ++++lvGag++GcEllKn++++G+    g++ v+Dmdt+e+snlnrqFLfr++dv k K+++aa+a+k++n
   Q: 452  YDGQIAVFGSKLQKILADQRYFLVGAGAIGCELLKNFAMIGLaseeGEVIVTDMDTIEKSNLNRQFLFRPSDVTKMKSDTAAAAVKQMN 540
           ***************************************************************************************** PP
   S: 86   pdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqkti 171
           p+ +++ah++++ +++e+++   Ff+ +++V++aldn++ar++++r+c+++r+pl+esgtlG++G+++v+i+ +te+ys+s+dpp+k+i
   Q: 541  PSFKITAHQNRVGPETERVYdddFFESLNGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNIQVVIPFVTESYSSSQDPPEKSI 629
           *******************9********************************************************************* PP
   S: 172  Pfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakt 248
           P+ctlk++pna+eht++wa            + + ++l +++++ e++ kl  +++ e++d+v +++++  + ++++++++a+++++ +
   Q: 630  PICTLKNFPNAIEHTLQWArdefeglfkqapENAMQYL-TDSKFMERTLKLPGAQPVEVLDAVYKSVVTDCPHSWADCVAWARNHWQCQ 717
           *****************************999999999.5566666667799************************************* PP
   S: 249  tinsikqllksfecdivtkskspfwv......................................................sfcsnaeal 283
           ++n+i+qll++f++d++t+s++pfw+                                                      +f + +   
   Q: 718  YSNNIRQLLHNFPPDQLTSSGAPFWSgpkrcphpldfstsndlhvdyvlaaanlfaqtyglpgstdragvvkilqdvkvpTFTPRSG-- 804
           ***********************************************************9999999998777777775552222221.. PP
   S: 284  qvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagni 365
              + +++d+e + ++++     l+ l+  l + e+ +  k + ++fekddd   ++d++ aa+nlrae+++i+p +d+++ k iag+i
   Q: 805  --VKIHVSDQELQNSNSSvddskLEELKSQLPTPESFRF-KLSPIDFEKDDDAnfHMDFIVAASNLRAENYDIPP-ADRHKSKLIAGKI 889
           ..1333333333333333334346777777777766554.4558*******************************.************* PP
   S: 366  ipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           ipaiatt+a+v Gl+++E++K+++g  k + +kn f+++a+
   Q: 890  IPAIATTTAAVVGLVCLELFKIIQGhkKLDSFKNGFMNLAL 930
           *************************999999*****99875 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MSSSPLSKKR RLSGTETKTE SHCSSSNSVR TDLSHTPANG MAKNGNDAEI DEGLYSRQLY 60
VLGHEAMKRM QNSNVLISGM RGLGVEIAKN VILGGVRSVT VHDQGDAEWR DLSSQFYLRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGTGTTGG TCCCGCCTGT AACGTGCACA TGTTGCTGCT TTGCTTTGCT TTCAACTGAA 60
ATAGAGTGAG GGGAAACGGC TCGGGAGCAG CCGGCCAGGG AGACGTCCAG TGGAAAAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0007409--P:axonogenesis
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	45.55	0.00e+00	895.00
IUUC-Aml-001311	Ailuropoda melanoleuca	76.86	0.00e+00	1719.00
IUUC-Atr-002684	Amborella trichopoda	44.18	0.00e+00	889.00
IUUC-Aca-004620	Anolis carolinensis	78.07	0.00e+00	1716.00
IUUC-Aly-005515	Arabidopsis lyrata	44.06	0.00e+00	910.00
IUUC-Ath-006891	Arabidopsis thaliana	44.14	0.00e+00	909.00
IUUC-Ago-007873	Ashbya gossypii	52.12	0.00e+00	1019.00
IUUC-Acl-008181	Aspergillus clavatus	54.39	0.00e+00	1060.00
IUUC-Afl-008455	Aspergillus flavus	53.73	0.00e+00	1016.00
IUUC-Afu-009065	Aspergillus fumigatus	54.44	0.00e+00	1081.00
IUUC-Ani-009371	Aspergillus nidulans	53.04	0.00e+00	1038.00
IUUC-Ang-009737	Aspergillus niger	54.32	0.00e+00	1060.00
IUUC-Aor-010007	Aspergillus oryzae	53.73	0.00e+00	1016.00
IUUC-Ate-010466	Aspergillus terreus	53.96	0.00e+00	1081.00
IUUC-Ame-010933	Astyanax mexicanus	86.20	0.00e+00	1831.00
IUUC-Bgr-012281	Blumeria graminis	52.10	0.00e+00	1046.00
IUUC-Bta-012767	Bos taurus	77.90	0.00e+00	1739.00
IUUC-Bci-013721	Botrytis cinerea	54.58	0.00e+00	1021.00
IUUC-Bdi-014843	Brachypodium distachyon	44.78	0.00e+00	862.00
IUUC-Bol-015665	Brassica oleracea	43.68	0.00e+00	895.00
IUUC-Bra-017252	Brassica rapa	43.30	0.00e+00	904.00
IUUC-Cel-018260	Caenorhabditis elegans	48.19	0.00e+00	945.00
IUUC-Cja-019152	Callithrix jacchus	77.43	0.00e+00	1723.00
IUUC-Cfa-020622	Canis familiaris	75.73	0.00e+00	1661.00
IUUC-Cpo-022526	Cavia porcellus	77.05	0.00e+00	1713.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	45.60	0.00e+00	872.00
IUUC-Csa-023780	Chlorocebus sabaeus	77.71	0.00e+00	1734.00
IUUC-Cin-025790	Ciona intestinalis	63.31	0.00e+00	1351.00
IUUC-Csv-026084	Ciona savignyi	59.93	0.00e+00	1332.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	54.31	0.00e+00	1095.00
IUUC-Cne-026960	Cryptococcus neoformans	56.56	0.00e+00	1110.00
IUUC-Cme-027290	Cyanidioschyzon merolae	44.74	0.00e+00	836.00
IUUC-Dre-028149	Danio rerio	86.48	0.00e+00	1875.00
IUUC-Dno-028884	Dasypus novemcinctus	77.24	0.00e+00	1724.00
IUUC-Dor-030229	Dipodomys ordii	74.32	0.00e+00	1643.00
IUUC-Dse-031524	Dothistroma septosporum	52.77	0.00e+00	1037.00
IUUC-Dme-032045	Drosophila melanogaster	59.51	0.00e+00	1281.00
IUUC-Ete-032544	Echinops telfairi	65.21	0.00e+00	691.00
IUUC-Eca-033330	Equus caballus	77.62	0.00e+00	1738.00
IUUC-Eeu-034717	Erinaceus europaeus	43.03	5.00e-166	578.00
IUUC-Fca-036255	Felis catus	77.71	0.00e+00	1724.00
IUUC-Fal-037445	Ficedula albicollis	46.44	0.00e+00	840.00
IUUC-Fox-038007	Fusarium oxysporum	53.92	7.00e-161	560.00
IUUC-Fso-038339	Fusarium solani	54.29	0.00e+00	1050.00
IUUC-Gmo-039338	Gadus morhua	84.21	0.00e+00	1789.00
IUUC-Ggr-039823	Gaeumannomyces graminis	53.90	0.00e+00	1105.00
IUUC-Gga-040365	Gallus gallus	45.31	0.00e+00	781.00
IUUC-Gac-041773	Gasterosteus aculeatus	87.93	0.00e+00	1868.00
IUUC-Gma-043198	Glycine max	44.08	0.00e+00	875.00
IUUC-Ggo-045336	Gorilla gorilla	77.62	0.00e+00	1719.00
IUUC-Hsa-045982	Homo sapiens	77.43	0.00e+00	1714.00
IUUC-Hvu-047418	Hordeum vulgare	44.84	0.00e+00	868.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	77.62	0.00e+00	1733.00
IUUC-Kpa-049112	Komagataella pastoris	50.39	0.00e+00	983.00
IUUC-Lch-050371	Latimeria chalumnae	81.11	0.00e+00	1784.00
IUUC-Lpe-051299	Leersia perrieri	43.70	0.00e+00	871.00
IUUC-Loc-052936	Lepisosteus oculatus	85.55	0.00e+00	1860.00
IUUC-Lma-053315	Leptosphaeria maculans	54.56	0.00e+00	1103.00
IUUC-Laf-053948	Loxodonta africana	76.02	0.00e+00	1672.00
IUUC-Mcc-055843	Macaca mulatta	77.71	0.00e+00	1735.00
IUUC-Meu-056258	Macropus eugenii	75.73	0.00e+00	1676.00
IUUC-Mor-057269	Magnaporthe oryzae	54.28	0.00e+00	1085.00
IUUC-Mpo-057435	Magnaporthe poae	54.63	0.00e+00	1087.00
IUUC-Mtr-058572	Medicago truncatula	43.99	0.00e+00	847.00
IUUC-Mla-059176	Melampsora laricipopulina	55.03	0.00e+00	1078.00
IUUC-Mvi-060437	Microbotryum violaceum	53.28	0.00e+00	1060.00
IUUC-Mmr-061405	Microcebus murinus	75.45	0.00e+00	1668.00
IUUC-Mdo-062032	Monodelphis domestica	75.19	0.00e+00	1661.00
IUUC-Mmu-063280	Mus musculus	77.43	0.00e+00	1718.00
IUUC-Mac-065505	Musa acuminata	45.48	0.00e+00	884.00
IUUC-Mpu-066409	Mustela putorius furo	77.43	0.00e+00	1735.00
IUUC-Mlu-067217	Myotis lucifugus	76.77	0.00e+00	1708.00
IUUC-Nfi-068407	Neosartorya fischeri	54.15	0.00e+00	1060.00
IUUC-Ncr-068698	Neurospora crassa	53.98	0.00e+00	1085.00
IUUC-Nle-070072	Nomascus leucogenys	74.18	0.00e+00	1607.00
IUUC-Opr-070715	Ochotona princeps	42.11	0.00e+00	746.00
IUUC-Ont-071671	Oreochromis niloticus	90.52	0.00e+00	1948.00
IUUC-Oan-073306	Ornithorhynchus anatinus	46.23	0.00e+00	702.00
IUUC-Ocu-074544	Oryctolagus cuniculus	78.47	0.00e+00	1749.00
IUUC-Oba-075120	Oryza barthii	44.02	0.00e+00	860.00
IUUC-Obr-076557	Oryza brachyantha	44.70	0.00e+00	846.00
IUUC-Ogl-077887	Oryza glaberrima	44.11	0.00e+00	865.00
IUUC-Ogu-078305	Oryza glumaepatula	43.46	0.00e+00	863.00
IUUC-Oin-079370	Oryza indica	43.03	0.00e+00	844.00
IUUC-Olo-081089	Oryza longistaminata	43.46	0.00e+00	863.00
IUUC-Ome-081942	Oryza meridionalis	44.11	0.00e+00	863.00
IUUC-Oni-082365	Oryza nivara	44.02	0.00e+00	864.00
IUUC-Opu-083977	Oryza punctata	44.31	0.00e+00	871.00
IUUC-Oru-084469	Oryza rufipogon	43.56	0.00e+00	867.00
IUUC-Osa-085949	Oryza sativa	44.02	0.00e+00	868.00
IUUC-Ola-087002	Oryzias latipes	91.38	0.00e+00	1966.00
IUUC-Olu-087687	Ostreococcus lucimarinus	44.16	0.00e+00	805.00
IUUC-Oga-088594	Otolemur garnettii	77.17	0.00e+00	1711.00
IUUC-Oar-090068	Ovis aries	77.83	0.00e+00	1739.00
IUUC-Ptr-090581	Pan troglodytes	44.39	0.00e+00	751.00
IUUC-Pan-092114	Papio anubis	77.81	0.00e+00	1737.00
IUUC-Pma-094214	Petromyzon marinus	57.71	4.00e-53	200.00
IUUC-Pno-095154	Phaeosphaeria nodorum	53.24	0.00e+00	1098.00
IUUC-Ppa-095227	Physcomitrella patens	44.93	0.00e+00	872.00
IUUC-Pab-097861	Pongo abelii	77.43	0.00e+00	1705.00
IUUC-Pop-098934	Populus trichocarpa	43.62	0.00e+00	907.00
IUUC-Pca-100347	Procavia capensis	74.19	0.00e+00	1367.00
IUUC-Ppe-101298	Prunus persica	43.94	0.00e+00	845.00
IUUC-Pva-102584	Pteropus vampyrus	77.71	0.00e+00	1756.00
IUUC-Pgr-103336	Puccinia graminis	52.80	0.00e+00	1043.00
IUUC-Ptt-103939	Puccinia triticina	52.38	0.00e+00	1040.00
IUUC-Pte-104200	Pyrenophora teres	52.59	0.00e+00	1098.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	52.68	0.00e+00	1085.00
IUUC-Rno-105462	Rattus norvegicus	77.81	0.00e+00	1716.00
IUUC-Sce-106245	Saccharomyces cerevisiae	50.39	0.00e+00	1021.00
IUUC-Sha-107142	Sarcophilus harrisii	76.20	0.00e+00	1697.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	54.03	0.00e+00	1099.00
IUUC-Spo-108034	Schizosaccharomyces pombe	54.30	0.00e+00	1065.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	54.78	0.00e+00	1046.00
IUUC-Smo-109211	Selaginella moellendorffii	44.12	0.00e+00	872.00
IUUC-Sit-110281	Setaria italica	44.71	0.00e+00	891.00
IUUC-Sly-111237	Solanum lycopersicum	45.19	0.00e+00	860.00
IUUC-Stu-112109	Solanum tuberosum	44.70	0.00e+00	903.00
IUUC-Sar-113737	Sorex araneus	77.62	0.00e+00	1725.00
IUUC-Sbi-114089	Sorghum bicolor	45.19	0.00e+00	890.00
IUUC-Sre-115148	Sporisorium reilianum	54.39	0.00e+00	1072.00
IUUC-Ssc-115777	Sus scrofa	77.74	0.00e+00	1731.00
IUUC-Tru-118742	Takifugu rubripes	90.13	0.00e+00	1883.00
IUUC-Tni-120401	Tetraodon nigroviridis	89.56	0.00e+00	1877.00
IUUC-Tca-121672	Theobroma cacao	44.57	0.00e+00	890.00
IUUC-Tre-122009	Trichoderma reesei	53.42	0.00e+00	1043.00
IUUC-Tvi-122259	Trichoderma virens	53.86	0.00e+00	1031.00
IUUC-Tae-125113	Triticum aestivum	45.26	0.00e+00	852.00
IUUC-Tur-126330	Triticum urartu	45.36	0.00e+00	892.00
IUUC-Tme-127055	Tuber melanosporum	51.91	0.00e+00	967.00
IUUC-Tbe-127487	Tupaia belangeri	73.93	0.00e+00	832.00
IUUC-Ttr-128331	Tursiops truncatus	77.43	0.00e+00	1713.00
IUUC-Uma-129387	Ustilago maydis	55.01	0.00e+00	1063.00
IUUC-Vda-129977	Verticillium dahliae	53.65	0.00e+00	1004.00
IUUC-Vvi-130857	Vitis vinifera	43.91	0.00e+00	887.00
IUUC-Xtr-132026	Xenopus tropicalis	64.72	0.00e+00	1278.00
IUUC-Xma-133805	Xiphophorus maculatus	97.89	0.00e+00	2052.00
IUUC-Yli-134547	Yarrowia lipolytica	51.58	0.00e+00	1069.00
IUUC-Zma-135052	Zea mays	44.95	0.00e+00	890.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence