iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069436

Ensembl Protein ID

ENSNLEP00000000210.2

UniProt Accession

G1QH27; G1QH27_NOMLE

Genbank Protein ID

ENSNLEP00000000210

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01088222

Gene Name

HCLS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000000180.1	ENSNLET00000000225.1	ENSNLEP00000000210.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.40e-12	44.9	454	504

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            +lydy+++ +deL++   dv++ i  e  +egW++g    +g  GlfP+n+v+ 
   Q: 454  VALYDYQGEGSDELSFDPDDVITDI--EMVEEGWWRG--RIHGHFGLFPANYVKL 504
           58**********************9..99********..8*************85 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

FLTPKWQQPE RESVWTREAR RLEQRLVQVE MWKSVVGHDV SVSVETQGDD WDTDPDFVND 60
ISEKEQRWGA KTIEGSGRTE HINIHQLRNK VSEEHDVLKK KEMESGPKAS HGYGGRFGVE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTTTCTCAC TCCGAAGTGG CAGCAGCCAG AGAGGGAGTC GGTGTGGACG CGAGAAGCCA 60
GGCGCTTAGA ACAGAGGCTC GTACAGGTGG AGGTGGGTAC TCTGAGCCAT GGGACAGTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030833--P:regulation of actin filament polymerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001194	Ailuropoda melanoleuca	85.27	0.00e+00	733.00
IUUC-Apl-003745	Anas platyrhynchos	57.20	4.00e-85	308.00
IUUC-Aca-004438	Anolis carolinensis	63.39	8.00e-81	294.00
IUUC-Ame-011504	Astyanax mexicanus	54.06	1.00e-79	290.00
IUUC-Bta-012591	Bos taurus	85.77	0.00e+00	676.00
IUUC-Cel-018639	Caenorhabditis elegans	61.82	2.00e-16	80.50
IUUC-Cja-019982	Callithrix jacchus	92.69	0.00e+00	744.00
IUUC-Cfa-020262	Canis familiaris	82.41	0.00e+00	654.00
IUUC-Cpo-021362	Cavia porcellus	86.53	0.00e+00	652.00
IUUC-Csa-023911	Chlorocebus sabaeus	95.46	0.00e+00	769.00
IUUC-Cin-025677	Ciona intestinalis	55.56	1.00e-66	247.00
IUUC-Csv-026140	Ciona savignyi	59.68	4.00e-64	239.00
IUUC-Dre-028127	Danio rerio	71.83	1.00e-94	340.00
IUUC-Dno-029332	Dasypus novemcinctus	64.58	4.00e-90	325.00
IUUC-Dor-030437	Dipodomys ordii	77.15	2.00e-171	595.00
IUUC-Dme-031931	Drosophila melanogaster	44.48	9.00e-72	264.00
IUUC-Ete-033160	Echinops telfairi	75.06	4.00e-153	534.00
IUUC-Eca-033269	Equus caballus	83.50	0.00e+00	716.00
IUUC-Eeu-035032	Erinaceus europaeus	72.44	3.00e-121	428.00
IUUC-Fca-035999	Felis catus	80.80	0.00e+00	743.00
IUUC-Fal-037107	Ficedula albicollis	50.38	3.00e-121	428.00
IUUC-Gmo-038507	Gadus morhua	63.16	4.00e-18	85.90
IUUC-Gga-040335	Gallus gallus	68.20	3.00e-107	382.00
IUUC-Gac-042253	Gasterosteus aculeatus	69.48	2.00e-88	320.00
IUUC-Ggo-044505	Gorilla gorilla	90.06	0.00e+00	738.00
IUUC-Hsa-046728	Homo sapiens	98.02	0.00e+00	642.00
IUUC-Itr-048592	Ictidomys tridecemlineatus	67.88	3.00e-166	577.00
IUUC-Lch-050221	Latimeria chalumnae	78.70	4.00e-101	361.00
IUUC-Loc-052855	Lepisosteus oculatus	61.57	3.00e-86	312.00
IUUC-Laf-054202	Loxodonta africana	82.41	0.00e+00	674.00
IUUC-Mcc-055824	Macaca mulatta	95.16	0.00e+00	765.00
IUUC-Mga-059791	Meleagris gallopavo	56.59	3.00e-85	308.00
IUUC-Mmr-061281	Microcebus murinus	76.97	9.00e-173	599.00
IUUC-Mdo-062515	Monodelphis domestica	68.31	3.00e-153	534.00
IUUC-Mmu-064341	Mus musculus	81.47	0.00e+00	678.00
IUUC-Mpu-066565	Mustela putorius furo	87.16	0.00e+00	696.00
IUUC-Mlu-066942	Myotis lucifugus	81.35	0.00e+00	687.00
IUUC-Opr-070288	Ochotona princeps	80.29	1.00e-169	589.00
IUUC-Ont-071712	Oreochromis niloticus	74.65	2.00e-92	333.00
IUUC-Oan-073528	Ornithorhynchus anatinus	42.03	5.00e-45	175.00
IUUC-Ocu-074686	Oryctolagus cuniculus	84.43	0.00e+00	632.00
IUUC-Ola-086894	Oryzias latipes	59.79	3.00e-95	342.00
IUUC-Oga-088585	Otolemur garnettii	78.85	0.00e+00	672.00
IUUC-Oar-089686	Ovis aries	85.80	0.00e+00	711.00
IUUC-Ptr-090461	Pan troglodytes	93.37	0.00e+00	713.00
IUUC-Pan-091887	Papio anubis	97.26	0.00e+00	754.00
IUUC-Psi-093785	Pelodiscus sinensis	53.14	3.00e-141	494.00
IUUC-Pma-094161	Petromyzon marinus	63.58	4.00e-56	212.00
IUUC-Pfo-097391	Poecilia formosa	69.48	2.00e-90	325.00
IUUC-Pab-098222	Pongo abelii	97.23	0.00e+00	824.00
IUUC-Pca-100668	Procavia capensis	82.05	0.00e+00	678.00
IUUC-Pva-102767	Pteropus vampyrus	73.39	9.00e-170	589.00
IUUC-Rno-106001	Rattus norvegicus	84.13	0.00e+00	688.00
IUUC-Sha-106912	Sarcophilus harrisii	53.18	4.00e-137	481.00
IUUC-Sar-113338	Sorex araneus	76.15	2.00e-171	594.00
IUUC-Ssc-116027	Sus scrofa	84.79	0.00e+00	718.00
IUUC-Tgu-117472	Taeniopygia guttata	58.69	1.00e-152	533.00
IUUC-Tru-118718	Takifugu rubripes	64.62	3.00e-84	305.00
IUUC-Tni-119931	Tetraodon nigroviridis	58.30	9.00e-95	340.00
IUUC-Tre-122167	Trichoderma reesei	57.14	3.00e-11	63.90
IUUC-Tvi-122614	Trichoderma virens	57.14	2.00e-11	64.30
IUUC-Xtr-131797	Xenopus tropicalis	68.54	3.00e-81	295.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence