iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111775

Ensembl Protein ID

Solyc06g066730.2.1

UniProt Accession

K4C7U7; K4C7U7_SOLLC

Protein Name

Coatomer subunit beta'

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc06g066730.2	Solyc06g066730.2.1	Solyc06g066730.2.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-35	119.1	184	224
UBD/Beta-Prp	6.00e-68	229.9	14	289

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H  +v+c+++    d ++l++GsdD+t kvWD+ t  ++++
   Q: 184  HLKGVNCVDYftgGDkPYLITGSDDHTAKVWDYQTRSCVQT 224
           8889****966*9778*****************99999885 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvls 99
           +++++++v+ +p +++++t+ ++gt+ +w+++t+++ +s++  e +v++ kf+ +++++v gs+D++i+v++++t + v ++++h+d++++
   Q: 14   RSERVKAVDLHPTEPWILTSLYSGTLCIWNYQTQTMAQSFEVTELPVRSAKFIARKQWIVAGSDDMFIRVYNYNTMDKVKVFEAHTDYIRC 104
           5678999************************************************************************************ PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvysls.. 187
           ++++p+  +++s s+d  i++wd+e+g++  ++++gh++ v+ v+++p++ n ++s+slDrt+++W+l + +   tl   h + v++++  
   Q: 105  VAVHPTLPYVLSSSDDMLIKLWDWEKGWVCTQIFEGHSHYVMQVTFNPKDtNTFASASLDRTIKIWNLGSPDPNFTLDA-HLKGVNCVDyf 194
           ****************************9999*********************************************98.*********64 PP
   S: 188  fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdn 278
              ++++l++gs+d t k+wd+qt +cv+tl+ght nv+ v f+p+  ++++gs+Dg++riW  ++  l +tl++  ++v+++ +++ +++
   Q: 195  TGGDKPYLITGSDDHTAKVWDYQTRSCVQTLEGHTHNVSAVCFHPDLPIIMTGSEDGTVRIWHATTYRLENTLNYGLERVWAIGYMKGSRR 285
           44555******************************************************************************99766666 PP
   S: 279  vlvl 282
           v++ 
   Q: 286  VVIG 289
           6643 PP

Organism

Solanum lycopersicum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLEIKRK LAQRSERVKA VDLHPTEPWI LTSLYSGTLC IWNYQTQTMA QSFEVTELPV 60
RSAKFIARKQ WIVAGSDDMF IRVYNYNTMD KVKVFEAHTD YIRCVAVHPT LPYVLSSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTACGTC CATTAGTTTC AGTAGGTTAT TAATGCGTTC GCATTATGTT AAAACTTAGA 60
TCTGATTCAA ATCCAATTCG ATTTAATGGT GGTAACGGAT CACTATGTTG AGGATTGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002154	Ailuropoda melanoleuca	60.50	0.00e+00	1112.00
IUUC-Atr-003090	Amborella trichopoda	77.93	0.00e+00	1514.00
IUUC-Apl-003976	Anas platyrhynchos	60.38	0.00e+00	1116.00
IUUC-Aca-004301	Anolis carolinensis	59.72	0.00e+00	1117.00
IUUC-Aly-006508	Arabidopsis lyrata	83.73	0.00e+00	1593.00
IUUC-Ath-007635	Arabidopsis thaliana	82.92	0.00e+00	1585.00
IUUC-Ago-007914	Ashbya gossypii	46.12	0.00e+00	730.00
IUUC-Acl-008237	Aspergillus clavatus	53.87	0.00e+00	919.00
IUUC-Afl-008535	Aspergillus flavus	53.94	0.00e+00	868.00
IUUC-Afu-008845	Aspergillus fumigatus	53.07	0.00e+00	905.00
IUUC-Ani-009135	Aspergillus nidulans	55.56	0.00e+00	901.00
IUUC-Ang-009654	Aspergillus niger	55.86	0.00e+00	825.00
IUUC-Aor-009939	Aspergillus oryzae	52.64	0.00e+00	926.00
IUUC-Ate-010355	Aspergillus terreus	54.06	0.00e+00	890.00
IUUC-Bgr-012249	Blumeria graminis	53.57	0.00e+00	899.00
IUUC-Bci-013866	Botrytis cinerea	55.39	0.00e+00	902.00
IUUC-Bdi-015046	Brachypodium distachyon	79.98	0.00e+00	1526.00
IUUC-Bol-016271	Brassica oleracea	82.61	0.00e+00	1589.00
IUUC-Bra-017758	Brassica rapa	82.12	0.00e+00	1576.00
IUUC-Cja-019145	Callithrix jacchus	60.67	0.00e+00	1116.00
IUUC-Cfa-020564	Canis familiaris	60.55	0.00e+00	1115.00
IUUC-Cpo-022201	Cavia porcellus	60.50	0.00e+00	1113.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	65.74	0.00e+00	1119.00
IUUC-Cho-024454	Choloepus hoffmanni	57.94	0.00e+00	928.00
IUUC-Cin-025681	Ciona intestinalis	58.82	0.00e+00	1001.00
IUUC-Csv-026012	Ciona savignyi	57.85	0.00e+00	978.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	50.37	0.00e+00	802.00
IUUC-Dre-027846	Danio rerio	60.38	0.00e+00	1122.00
IUUC-Dse-031268	Dothistroma septosporum	53.51	0.00e+00	908.00
IUUC-Eca-034180	Equus caballus	59.12	0.00e+00	1071.00
IUUC-Eeu-035086	Erinaceus europaeus	49.89	1.00e-128	453.00
IUUC-Fca-036265	Felis catus	60.55	0.00e+00	1113.00
IUUC-Fal-037202	Ficedula albicollis	57.73	0.00e+00	1069.00
IUUC-Fox-037711	Fusarium oxysporum	54.52	0.00e+00	848.00
IUUC-Fso-038268	Fusarium solani	53.76	0.00e+00	853.00
IUUC-Gmo-039046	Gadus morhua	60.12	0.00e+00	1108.00
IUUC-Ggr-039863	Gaeumannomyces graminis	53.72	0.00e+00	874.00
IUUC-Gga-041112	Gallus gallus	60.79	0.00e+00	1122.00
IUUC-Ggo-044984	Gorilla gorilla	60.67	0.00e+00	1115.00
IUUC-Hsa-046698	Homo sapiens	60.55	0.00e+00	1115.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	60.50	0.00e+00	1110.00
IUUC-Kpa-049265	Komagataella pastoris	50.56	0.00e+00	855.00
IUUC-Lpe-051579	Leersia perrieri	81.22	0.00e+00	1529.00
IUUC-Lma-053218	Leptosphaeria maculans	52.04	0.00e+00	871.00
IUUC-Laf-053757	Loxodonta africana	60.48	0.00e+00	1108.00
IUUC-Mcc-054859	Macaca mulatta	60.67	0.00e+00	1116.00
IUUC-Meu-056174	Macropus eugenii	51.89	3.00e-112	399.00
IUUC-Mor-057264	Magnaporthe oryzae	53.84	0.00e+00	858.00
IUUC-Mpo-057538	Magnaporthe poae	53.60	0.00e+00	880.00
IUUC-Mtr-058618	Medicago truncatula	85.02	0.00e+00	1592.00
IUUC-Mla-058937	Melampsora laricipopulina	52.49	0.00e+00	899.00
IUUC-Mga-059875	Meleagris gallopavo	60.52	0.00e+00	1118.00
IUUC-Mvi-060240	Microbotryum violaceum	52.96	0.00e+00	914.00
IUUC-Mmr-061261	Microcebus murinus	60.55	0.00e+00	1115.00
IUUC-Mdo-062076	Monodelphis domestica	59.77	0.00e+00	1122.00
IUUC-Mmu-063324	Mus musculus	60.55	0.00e+00	1115.00
IUUC-Mpu-065961	Mustela putorius furo	60.55	0.00e+00	1113.00
IUUC-Nfi-068277	Neosartorya fischeri	53.39	0.00e+00	899.00
IUUC-Ncr-068659	Neurospora crassa	53.22	0.00e+00	906.00
IUUC-Nle-069034	Nomascus leucogenys	60.67	0.00e+00	1115.00
IUUC-Ocu-074522	Oryctolagus cuniculus	60.00	0.00e+00	1110.00
IUUC-Obr-076201	Oryza brachyantha	81.76	0.00e+00	1545.00
IUUC-Oin-079856	Oryza indica	80.64	0.00e+00	1517.00
IUUC-Ome-081554	Oryza meridionalis	76.84	0.00e+00	1426.00
IUUC-Opu-083400	Oryza punctata	78.96	0.00e+00	1506.00
IUUC-Olu-087655	Ostreococcus lucimarinus	66.33	0.00e+00	1158.00
IUUC-Oga-088163	Otolemur garnettii	57.21	0.00e+00	1057.00
IUUC-Oar-089842	Ovis aries	60.43	0.00e+00	1115.00
IUUC-Ptr-090501	Pan troglodytes	60.67	0.00e+00	1116.00
IUUC-Pan-092011	Papio anubis	60.67	0.00e+00	1115.00
IUUC-Psi-093308	Pelodiscus sinensis	60.91	0.00e+00	1120.00
IUUC-Ppa-095911	Physcomitrella patens	75.11	0.00e+00	1437.00
IUUC-Pop-099634	Populus trichocarpa	85.27	0.00e+00	1603.00
IUUC-Pca-100965	Procavia capensis	59.67	0.00e+00	1078.00
IUUC-Ppe-101470	Prunus persica	86.04	0.00e+00	1646.00
IUUC-Pgr-103453	Puccinia graminis	52.38	0.00e+00	910.00
IUUC-Ptt-103868	Puccinia triticina	52.50	0.00e+00	910.00
IUUC-Pte-104274	Pyrenophora teres	53.46	0.00e+00	905.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	51.88	0.00e+00	855.00
IUUC-Rno-105979	Rattus norvegicus	53.44	0.00e+00	821.00
IUUC-Sce-106269	Saccharomyces cerevisiae	46.62	0.00e+00	767.00
IUUC-Sha-106905	Sarcophilus harrisii	59.84	0.00e+00	1122.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	46.27	0.00e+00	782.00
IUUC-Spo-108299	Schizosaccharomyces pombe	46.91	0.00e+00	804.00
IUUC-Sre-115040	Sporisorium reilianum	51.43	0.00e+00	897.00
IUUC-Ssc-115593	Sus scrofa	60.43	0.00e+00	1113.00
IUUC-Tgu-117239	Taeniopygia guttata	58.66	0.00e+00	1119.00
IUUC-Tca-121613	Theobroma cacao	87.23	0.00e+00	1675.00
IUUC-Tre-122072	Trichoderma reesei	53.60	0.00e+00	901.00
IUUC-Tvi-122546	Trichoderma virens	53.23	0.00e+00	884.00
IUUC-Tae-125395	Triticum aestivum	80.48	0.00e+00	1551.00
IUUC-Tme-127041	Tuber melanosporum	53.66	0.00e+00	916.00
IUUC-Ttr-129294	Tursiops truncatus	60.43	0.00e+00	1111.00
IUUC-Uma-129351	Ustilago maydis	50.48	0.00e+00	893.00
IUUC-Vda-129716	Verticillium dahliae	54.47	0.00e+00	924.00
IUUC-Vpa-130037	Vicugna pacos	50.42	1.00e-132	466.00
IUUC-Vvi-131689	Vitis vinifera	88.63	0.00e+00	1605.00
IUUC-Xtr-132633	Xenopus tropicalis	58.49	0.00e+00	1119.00
IUUC-Yli-134455	Yarrowia lipolytica	50.25	0.00e+00	823.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence