iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007137

UUCD1 version

UUC-ArT-00892

Ensembl Protein ID

AT5G67320.1

UniProt Accession

Q9FN19; Q56Y40; HOS15_ARATH

Genbank Protein ID

BAB09017.1; AED98328.1; AAL15328.1; AAN28871.1; BAD94649.1

Protein Name

WD40 repeat-containing protein HOS15; HIGH OSMOTIC STRESS GENE EXPRESSION 15

Genbank Nucleotide ID

AB007645; CP002688; AY057698; AY143932; AK221483

Gene Name

HOS15; At5g67320; K8K14.4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G67320	AT5G67320.1	AT5G67320.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-50	167.0	539	577
UBD/Beta-Prp	2.20e-82	277.5	320	612

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH ++v++laf ++  +++sGs D++i++W++++g+ +k
   Q: 539  GHREPVYSLAFsPNgEYIASGSLDKSIHIWSIKEGKIVK 577
           8***********777*****************9999887 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsf 102
           ++++ k+v t +++  +++llatgs dg  ++w +    l+++ls+h++++ ++k++++g++l+tgs Drt+ vwd+++ +  + ++ h+   l++++
   Q: 320  SNEKSKDVTT-LDWNGEGTLLATGSCDGQARIWTLNG-ELISTLSKHKGPIFSLKWNKKGDYLLTGSVDRTAVVWDVKAEEWKQQFEFHSGPTLDVDW 415
           4566677777.***********************987.999********************************************************* PP
   S: 103  spsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng........ 192
              + ++++ s d++i + ++ +    + t++gh+g vncv+++p+g+ll+s+s+D+t ++W++k+ + +++l++ ht+ +y + ++++g        
   Q: 416  RN-NVSFATSSTDSMIYLCKIGETRPAK-TFTGHQGEVNCVKWDPTGSLLASCSDDSTAKIWNIKQSTFVHDLRE-HTKEIYTIRWSPTGpgtnnpnk 510
           99.8899********************9.*********************************************9.*********************9 PP
   S: 193  .kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskv 289
              l+s+s d+tvklwd + g+++ ++ngh+++v+s++fspn+e+++sgs D+si iW ++ g+++kt+++  +  i   +++ ++n+++++ +d++v
   Q: 511  qLTLASASFDSTVKLWDAELGKMLCSFNGHREPVYSLAFSPNGEYIASGSLDKSIHIWSIKEGKIVKTYTG--NGGIFEVCWNKEGNKIAACFADNSV 606
           999********************************************************************..4455556679999999999999999 PP
   S: 290  niwklk 295
            +++++
   Q: 607  CVLDFR 612
           999986 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Acts as repressor of cold stress-regulated gene expression. Interacts specifically with and promotes deacetylation of histone H4. Plays a role in gene regulation for plant acclimation and tolerance to cold stress.

Protein Sequence
(Fasta)

MSSLTSVELN FLVFRYLQES GFTHAAFTLG YEAGINKSNI DGNMVPPGAL IKFVQKGLQY 60
MEMEANLSNS EVDIDEDFSF FQPLDLISKD VKELQDMLRE KKRKERDMEK ERDRSKENDK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGAAGAG TTTATAATCT CGAGAAATCT TTTTGGGCGA CGTTGTTTGC TCGGAGCTCT 60
TTCTCCGATT TGTCTCCATT TTCGGTGATT TAAAGTTAGG ATTTGGCTGT GGAGATGTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0346--Stress response
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0000118--C:histone deacetylase complex
GO:0005634--C:nucleus
GO:0003714--F:transcription corepressor activity
GO:0016575--P:histone deacetylation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0009409--P:response to cold
GO:0006351--P:transcription, DNA-templated

KEGG

ath:AT5G67320

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000916	Aegilops tauschii	72.54	2.00e-65	240.00
IUUC-Aml-001717	Ailuropoda melanoleuca	59.50	2.00e-123	435.00
IUUC-Atr-002514	Amborella trichopoda	74.60	5.00e-170	590.00
IUUC-Apl-003708	Anas platyrhynchos	59.50	3.00e-123	434.00
IUUC-Aca-004611	Anolis carolinensis	59.23	1.00e-122	432.00
IUUC-Aly-005622	Arabidopsis lyrata	96.06	0.00e+00	768.00
IUUC-Ame-011601	Astyanax mexicanus	59.68	7.00e-126	443.00
IUUC-Bta-013202	Bos taurus	59.50	4.00e-131	461.00
IUUC-Bdi-014315	Brachypodium distachyon	71.13	5.00e-162	563.00
IUUC-Bol-016277	Brassica oleracea	87.68	0.00e+00	729.00
IUUC-Bra-016944	Brassica rapa	87.56	0.00e+00	736.00
IUUC-Cja-018832	Callithrix jacchus	59.50	3.00e-123	434.00
IUUC-Cfa-020029	Canis familiaris	59.50	3.00e-123	434.00
IUUC-Cpo-021682	Cavia porcellus	59.23	8.00e-131	459.00
IUUC-Cre-022979	Chlamydomonas reinhardtii	57.92	1.00e-121	429.00
IUUC-Csa-024075	Chlorocebus sabaeus	59.50	3.00e-123	434.00
IUUC-Cin-025704	Ciona intestinalis	55.87	4.00e-129	454.00
IUUC-Csv-026257	Ciona savignyi	56.68	6.00e-128	450.00
IUUC-Cme-027258	Cyanidioschyzon merolae	42.79	3.00e-91	328.00
IUUC-Dre-027906	Danio rerio	59.41	3.00e-125	441.00
IUUC-Dno-029196	Dasypus novemcinctus	59.50	3.00e-123	434.00
IUUC-Dor-030732	Dipodomys ordii	59.10	5.00e-119	420.00
IUUC-Dme-031939	Drosophila melanogaster	55.97	2.00e-117	416.00
IUUC-Ete-033150	Echinops telfairi	58.61	9.00e-109	386.00
IUUC-Eca-033897	Equus caballus	58.95	2.00e-130	458.00
IUUC-Eeu-034952	Erinaceus europaeus	52.37	2.00e-101	362.00
IUUC-Fca-035734	Felis catus	59.50	3.00e-123	434.00
IUUC-Fal-037185	Ficedula albicollis	59.50	2.00e-123	434.00
IUUC-Gmo-038870	Gadus morhua	59.50	2.00e-129	455.00
IUUC-Gga-041161	Gallus gallus	59.50	2.00e-123	435.00
IUUC-Gac-041844	Gasterosteus aculeatus	59.23	1.00e-131	462.00
IUUC-Gma-043369	Glycine max	77.75	0.00e+00	668.00
IUUC-Ggo-044882	Gorilla gorilla	59.50	3.00e-123	434.00
IUUC-Hsa-046488	Homo sapiens	59.50	3.00e-123	434.00
IUUC-Itr-047958	Ictidomys tridecemlineatus	59.50	3.00e-122	431.00
IUUC-Kpa-049338	Komagataella pastoris	29.07	3.00e-28	119.00
IUUC-Lch-050672	Latimeria chalumnae	59.50	1.00e-123	436.00
IUUC-Lpe-051084	Leersia perrieri	69.10	3.00e-163	567.00
IUUC-Loc-052030	Lepisosteus oculatus	60.33	6.00e-133	466.00
IUUC-Laf-054280	Loxodonta africana	59.23	7.00e-131	459.00
IUUC-Mcc-055203	Macaca mulatta	59.50	4.00e-123	434.00
IUUC-Meu-056563	Macropus eugenii	64.14	8.00e-86	310.00
IUUC-Mtr-058624	Medicago truncatula	62.90	4.00e-43	168.00
IUUC-Mga-059660	Meleagris gallopavo	59.50	2.00e-123	435.00
IUUC-Mvi-060557	Microbotryum violaceum	37.86	2.00e-73	269.00
IUUC-Mmr-060925	Microcebus murinus	59.50	2.00e-122	432.00
IUUC-Mdo-062078	Monodelphis domestica	59.50	2.00e-123	435.00
IUUC-Mmu-063603	Mus musculus	59.50	1.00e-123	436.00
IUUC-Mac-065508	Musa acuminata	55.66	9.00e-142	496.00
IUUC-Mpu-066741	Mustela putorius furo	59.50	3.00e-123	434.00
IUUC-Mlu-068152	Myotis lucifugus	59.50	3.00e-123	434.00
IUUC-Nle-069229	Nomascus leucogenys	59.50	3.00e-123	434.00
IUUC-Opr-070277	Ochotona princeps	48.74	1.00e-89	323.00
IUUC-Ont-071569	Oreochromis niloticus	60.61	4.00e-133	467.00
IUUC-Oan-073562	Ornithorhynchus anatinus	59.23	5.00e-131	460.00
IUUC-Ocu-074280	Oryctolagus cuniculus	59.50	2.00e-123	435.00
IUUC-Oba-075618	Oryza barthii	53.31	0.00e+00	646.00
IUUC-Obr-076718	Oryza brachyantha	69.70	6.00e-161	560.00
IUUC-Ogl-077302	Oryza glaberrima	54.85	0.00e+00	680.00
IUUC-Ogu-078718	Oryza glumaepatula	54.70	0.00e+00	679.00
IUUC-Oin-079515	Oryza indica	46.92	2.00e-126	446.00
IUUC-Olo-080427	Oryza longistaminata	73.78	1.00e-154	539.00
IUUC-Ome-081696	Oryza meridionalis	54.08	0.00e+00	664.00
IUUC-Oni-082137	Oryza nivara	54.70	0.00e+00	679.00
IUUC-Opu-083505	Oryza punctata	44.00	6.00e-39	154.00
IUUC-Oru-085276	Oryza rufipogon	54.70	0.00e+00	680.00
IUUC-Osa-085791	Oryza sativa	54.70	0.00e+00	679.00
IUUC-Ola-087365	Oryzias latipes	58.68	2.00e-130	458.00
IUUC-Olu-087589	Ostreococcus lucimarinus	59.57	1.00e-135	476.00
IUUC-Oga-088357	Otolemur garnettii	57.30	7.00e-114	403.00
IUUC-Oar-089214	Ovis aries	59.23	6.00e-131	460.00
IUUC-Ptr-091532	Pan troglodytes	59.50	3.00e-123	434.00
IUUC-Pan-091927	Papio anubis	59.50	3.00e-123	434.00
IUUC-Psi-093358	Pelodiscus sinensis	59.23	1.00e-130	459.00
IUUC-Ppa-095868	Physcomitrella patens	69.29	1.00e-154	538.00
IUUC-Pfo-096158	Poecilia formosa	58.68	4.00e-131	461.00
IUUC-Pab-098705	Pongo abelii	59.50	3.00e-123	434.00
IUUC-Pop-098989	Populus trichocarpa	80.95	0.00e+00	635.00
IUUC-Pca-100256	Procavia capensis	58.77	8.00e-120	423.00
IUUC-Ppe-101572	Prunus persica	75.66	3.00e-160	557.00
IUUC-Pva-102616	Pteropus vampyrus	59.10	1.00e-119	422.00
IUUC-Rno-105411	Rattus norvegicus	59.50	3.00e-123	434.00
IUUC-Sce-106132	Saccharomyces cerevisiae	24.40	1.00e-31	130.00
IUUC-Sha-106636	Sarcophilus harrisii	59.50	2.00e-123	434.00
IUUC-Smo-109301	Selaginella moellendorffii	68.23	1.00e-150	525.00
IUUC-Sit-110710	Setaria italica	69.90	2.00e-167	581.00
IUUC-Sly-111336	Solanum lycopersicum	69.92	3.00e-165	574.00
IUUC-Stu-112786	Solanum tuberosum	62.79	6.00e-144	503.00
IUUC-Sar-112971	Sorex araneus	51.67	8.00e-110	390.00
IUUC-Sbi-114420	Sorghum bicolor	69.60	1.00e-168	585.00
IUUC-Sre-115175	Sporisorium reilianum	40.66	2.00e-54	206.00
IUUC-Ssc-115695	Sus scrofa	59.50	3.00e-123	434.00
IUUC-Tgu-116898	Taeniopygia guttata	58.95	8.00e-131	459.00
IUUC-Tru-118254	Takifugu rubripes	60.61	1.00e-132	466.00
IUUC-Tsy-119424	Tarsius syrichta	47.18	4.00e-83	301.00
IUUC-Tni-119986	Tetraodon nigroviridis	59.23	4.00e-131	460.00
IUUC-Tca-121739	Theobroma cacao	75.56	0.00e+00	640.00
IUUC-Tae-125368	Triticum aestivum	69.37	4.00e-162	563.00
IUUC-Tur-126856	Triticum urartu	67.87	2.00e-79	289.00
IUUC-Tme-127126	Tuber melanosporum	33.23	6.00e-44	171.00
IUUC-Tbe-127767	Tupaia belangeri	60.40	3.00e-111	394.00
IUUC-Ttr-128826	Tursiops truncatus	58.70	1.00e-113	402.00
IUUC-Uma-129469	Ustilago maydis	42.91	2.00e-54	206.00
IUUC-Vpa-130768	Vicugna pacos	58.77	1.00e-119	422.00
IUUC-Vvi-131193	Vitis vinifera	74.76	0.00e+00	636.00
IUUC-Xtr-132842	Xenopus tropicalis	56.91	3.00e-116	411.00
IUUC-Xma-134168	Xiphophorus maculatus	60.06	6.00e-132	463.00
IUUC-Yli-134648	Yarrowia lipolytica	28.57	1.00e-37	150.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence