iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007806

Ensembl Protein ID

AAS54297

UniProt Accession

Q750Y3; DCN1_ASHGO

Genbank Protein ID

AAS54297.2

Protein Name

Defective in cullin neddylation protein 1

Genbank Nucleotide ID

AE016820

Gene Name

DCN1; AGL194C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AGL194C	AAS54297	AAS54297

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/DCUN1	26.29	2.00e-16	83.20	IUUC-Ath-007531
UBD/Alpha-Helix/UBA	21.74	4.00e-13	71.20	IUUC-Cel-018441
E3 activity/DCUN1	23.74	9.00e-19	91.30	IUUC-Hsa-046089
UBD/Alpha-Helix/UBA	23.74	9.00e-19	91.30	IUUC-Hsa-046089
UBD/Alpha-Helix/UBA	23.74	5.00e-19	92.00	IUUC-Mmu-063954
E3 activity/DCUN1	36.05	4.00e-49	189.00	IUUC-Sce-106358
UBD/Alpha-Helix/UBA	36.05	4.00e-49	189.00	IUUC-Sce-106358

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ashbya gossypii

Functional Description
(View)

May contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity).

Protein Sequence
(Fasta)

MSNARQRELI REFLAVTSAT SAAAETYLER NHWSLDHALD DFYTQSGGGG RAEQYSAELV 60
ATFERYAAGG AMDTEALVRY VGDLGFQLED VATLCLARLL KVEELTADIS RFQFLSTWHG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTATGTC GATAGGGGCG GGGCGGAAGC ACGAGCAGCG ACTAACGACA GCAGAGCAAT 60
GCACGCCAAA GAGAACTGAT CAGGGAGTTC CTGGCGGTGA CCAGCGCGAC GAGCGCGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

KEGG

ago:AGOS_AGL194C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	25.41	2.00e-19	87.00
IUUC-Aml-001879	Ailuropoda melanoleuca	23.74	8.00e-21	91.70
IUUC-Atr-002697	Amborella trichopoda	27.64	2.00e-11	59.30
IUUC-Apl-003451	Anas platyrhynchos	24.05	3.00e-20	89.70
IUUC-Aca-005269	Anolis carolinensis	22.75	2.00e-19	87.40
IUUC-Aly-006285	Arabidopsis lyrata	24.50	1.00e-14	70.90
IUUC-Ath-007531	Arabidopsis thaliana	26.29	3.00e-18	83.20
IUUC-Acl-008172	Aspergillus clavatus	26.62	2.00e-21	94.00
IUUC-Afl-008569	Aspergillus flavus	30.47	8.00e-28	114.00
IUUC-Afu-009005	Aspergillus fumigatus	31.28	2.00e-21	92.80
IUUC-Ani-009241	Aspergillus nidulans	31.35	7.00e-23	98.60
IUUC-Ang-009664	Aspergillus niger	27.90	2.00e-20	90.10
IUUC-Aor-009902	Aspergillus oryzae	32.81	3.00e-12	61.60
IUUC-Ate-010414	Aspergillus terreus	29.69	4.00e-26	109.00
IUUC-Ame-011763	Astyanax mexicanus	24.51	1.00e-20	90.90
IUUC-Bgr-011991	Blumeria graminis	26.41	6.00e-17	79.00
IUUC-Bta-013561	Bos taurus	23.83	4.00e-19	85.90
IUUC-Bci-013824	Botrytis cinerea	29.02	1.00e-25	107.00
IUUC-Bdi-014138	Brachypodium distachyon	26.23	5.00e-19	85.50
IUUC-Bol-016110	Brassica oleracea	25.82	4.00e-18	82.80
IUUC-Bra-017111	Brassica rapa	25.41	1.00e-17	81.30
IUUC-Cel-018441	Caenorhabditis elegans	21.74	1.00e-14	71.20
IUUC-Cja-019502	Callithrix jacchus	24.12	3.00e-21	93.20
IUUC-Cfa-020523	Canis familiaris	23.83	6.00e-19	85.10
IUUC-Cpo-022196	Cavia porcellus	23.74	1.00e-20	91.30
IUUC-Cre-022620	Chlamydomonas reinhardtii	23.17	9.00e-15	72.00
IUUC-Csa-023551	Chlorocebus sabaeus	23.74	9.00e-21	91.30
IUUC-Cho-024373	Choloepus hoffmanni	23.05	6.00e-18	82.00
IUUC-Cin-025269	Ciona intestinalis	26.64	3.00e-20	89.70
IUUC-Csv-025976	Ciona savignyi	25.52	5.00e-14	68.90
IUUC-Cgl-026386	Colletotrichum gloeosporioides	32.24	1.00e-20	90.50
IUUC-Cne-026950	Cryptococcus neoformans	28.80	2.00e-15	74.30
IUUC-Cme-027199	Cyanidioschyzon merolae	25.62	9.30e-02	28.50
IUUC-Dre-028247	Danio rerio	24.02	1.00e-20	91.30
IUUC-Dno-028974	Dasypus novemcinctus	23.74	9.00e-21	91.30
IUUC-Dor-030143	Dipodomys ordii	26.17	9.00e-20	88.20
IUUC-Dse-031365	Dothistroma septosporum	26.62	3.00e-14	70.10
IUUC-Dme-032197	Drosophila melanogaster	23.94	2.00e-18	84.30
IUUC-Ete-032371	Echinops telfairi	24.12	5.00e-21	92.00
IUUC-Eca-033242	Equus caballus	23.74	9.00e-21	91.70
IUUC-Eeu-035317	Erinaceus europaeus	23.74	2.00e-20	90.50
IUUC-Fca-036061	Felis catus	23.74	1.00e-20	91.30
IUUC-Fal-037372	Ficedula albicollis	24.05	2.00e-20	90.50
IUUC-Fox-037884	Fusarium oxysporum	31.72	1.00e-14	70.50
IUUC-Fso-038150	Fusarium solani	30.61	2.00e-12	64.30
IUUC-Gmo-038885	Gadus morhua	25.29	2.00e-20	90.10
IUUC-Ggr-039959	Gaeumannomyces graminis	26.26	2.00e-10	58.50
IUUC-Gga-040935	Gallus gallus	23.74	5.00e-21	92.40
IUUC-Gac-041937	Gasterosteus aculeatus	24.51	3.00e-20	89.70
IUUC-Gma-043545	Glycine max	26.42	2.00e-18	83.60
IUUC-Ggo-044972	Gorilla gorilla	26.95	1.00e-20	90.90
IUUC-Hsa-046089	Homo sapiens	23.74	9.00e-21	91.30
IUUC-Hvu-047636	Hordeum vulgare	24.83	2.00e-08	50.10
IUUC-Itr-047902	Ictidomys tridecemlineatus	25.00	2.00e-18	83.20
IUUC-Kpa-049127	Komagataella pastoris	25.21	2.00e-26	110.00
IUUC-Lch-050600	Latimeria chalumnae	24.62	3.00e-21	93.20
IUUC-Lpe-051540	Leersia perrieri	24.18	1.00e-18	84.30
IUUC-Loc-052509	Lepisosteus oculatus	23.35	3.00e-20	89.70
IUUC-Lma-053103	Leptosphaeria maculans	30.94	2.00e-21	94.00
IUUC-Laf-053527	Loxodonta africana	24.12	4.00e-21	92.80
IUUC-Mcc-054700	Macaca mulatta	26.56	3.00e-20	90.10
IUUC-Meu-056535	Macropus eugenii	29.55	7.00e-16	75.50
IUUC-Mor-056909	Magnaporthe oryzae	23.22	7.00e-15	72.00
IUUC-Mpo-057299	Magnaporthe poae	23.25	3.00e-13	66.60
IUUC-Mtr-057964	Medicago truncatula	26.09	2.00e-18	83.60
IUUC-Mla-058990	Melampsora laricipopulina	25.80	7.00e-16	75.90
IUUC-Mga-060072	Meleagris gallopavo	24.31	2.00e-18	83.60
IUUC-Mvi-060312	Microbotryum violaceum	28.20	1.00e-17	80.90
IUUC-Mmr-060851	Microcebus murinus	23.74	9.00e-21	91.30
IUUC-Mdo-063074	Monodelphis domestica	23.92	2.00e-19	89.40
IUUC-Mmu-063954	Mus musculus	23.74	6.00e-21	92.00
IUUC-Mac-065016	Musa acuminata	26.55	2.00e-15	73.20
IUUC-Mpu-066870	Mustela putorius furo	23.83	6.00e-19	85.10
IUUC-Mlu-067701	Myotis lucifugus	23.35	8.00e-20	88.20
IUUC-Nfi-068610	Neosartorya fischeri	31.28	6.00e-21	91.30
IUUC-Ncr-068780	Neurospora crassa	27.80	9.00e-18	81.60
IUUC-Nle-069291	Nomascus leucogenys	23.74	9.00e-21	91.30
IUUC-Opr-070682	Ochotona princeps	30.28	1.00e-16	78.20
IUUC-Ont-071408	Oreochromis niloticus	24.61	1.00e-20	90.90
IUUC-Oan-073031	Ornithorhynchus anatinus	23.74	2.00e-20	90.50
IUUC-Ocu-074648	Oryctolagus cuniculus	23.74	9.00e-21	91.70
IUUC-Oba-074993	Oryza barthii	24.18	4.00e-19	85.90
IUUC-Obr-076341	Oryza brachyantha	24.59	4.00e-19	85.90
IUUC-Ogl-077099	Oryza glaberrima	24.18	4.00e-19	85.90
IUUC-Ogu-078285	Oryza glumaepatula	23.77	3.00e-18	82.80
IUUC-Oin-079441	Oryza indica	24.18	3.00e-19	86.70
IUUC-Olo-081037	Oryza longistaminata	24.18	3.00e-19	86.70
IUUC-Ome-081357	Oryza meridionalis	24.18	3.00e-19	86.70
IUUC-Oni-082632	Oryza nivara	24.18	3.00e-19	86.30
IUUC-Opu-083351	Oryza punctata	24.22	6.00e-19	85.10
IUUC-Oru-084306	Oryza rufipogon	24.18	3.00e-19	86.70
IUUC-Osa-085307	Oryza sativa	24.18	3.00e-19	86.70
IUUC-Ola-086868	Oryzias latipes	23.64	4.00e-20	89.40
IUUC-Olu-087646	Ostreococcus lucimarinus	25.59	2.00e-15	73.90
IUUC-Oga-089015	Otolemur garnettii	23.74	5.00e-21	92.40
IUUC-Oar-090405	Ovis aries	23.74	5.00e-21	92.40
IUUC-Ptr-090735	Pan troglodytes	23.74	9.00e-21	91.70
IUUC-Pan-092825	Papio anubis	26.56	2.00e-20	90.50
IUUC-Psi-093110	Pelodiscus sinensis	24.26	3.00e-20	89.70
IUUC-Pma-094196	Petromyzon marinus	31.69	1.00e-14	71.20
IUUC-Pno-095145	Phaeosphaeria nodorum	28.33	3.00e-19	86.70
IUUC-Ppa-095321	Physcomitrella patens	26.02	3.00e-18	82.80
IUUC-Pfo-096774	Poecilia formosa	25.10	7.00e-21	92.00
IUUC-Pab-098197	Pongo abelii	26.84	2.00e-19	86.70
IUUC-Pop-098821	Populus trichocarpa	33.94	3.00e-13	64.70
IUUC-Pca-100218	Procavia capensis	23.74	5.00e-20	89.00
IUUC-Ppe-102032	Prunus persica	27.94	1.00e-19	87.80
IUUC-Pva-102691	Pteropus vampyrus	25.49	6.00e-20	88.60
IUUC-Pgr-103633	Puccinia graminis	31.05	2.00e-24	103.00
IUUC-Ptt-103979	Puccinia triticina	32.95	1.00e-11	62.00
IUUC-Pyt-104428	Pyrenophora triticirepentis	27.19	1.00e-19	87.80
IUUC-Rno-105554	Rattus norvegicus	23.74	1.00e-20	91.30
IUUC-Sce-106358	Saccharomyces cerevisiae	36.05	3.00e-50	189.00
IUUC-Sha-106888	Sarcophilus harrisii	23.74	8.00e-21	91.70
IUUC-Sja-107938	Schizosaccharomyces japonicus	25.00	6.00e-14	68.90
IUUC-Spo-108207	Schizosaccharomyces pombe	24.88	8.00e-14	68.60
IUUC-Ssl-108410	Sclerotinia sclerotiorum	28.35	1.00e-23	101.00
IUUC-Smo-108750	Selaginella moellendorffii	23.98	2.00e-14	69.70
IUUC-Sit-110052	Setaria italica	26.12	3.00e-21	92.80
IUUC-Sly-111489	Solanum lycopersicum	25.00	5.00e-19	85.50
IUUC-Stu-112517	Solanum tuberosum	25.20	1.00e-17	81.30
IUUC-Sar-113051	Sorex araneus	38.46	2.00e-12	63.90
IUUC-Sbi-114082	Sorghum bicolor	26.02	1.00e-20	91.30
IUUC-Sre-115221	Sporisorium reilianum	25.00	3.00e-05	40.00
IUUC-Ssc-115547	Sus scrofa	23.74	9.00e-21	91.30
IUUC-Tgu-117147	Taeniopygia guttata	23.74	5.00e-21	92.40
IUUC-Tru-118119	Takifugu rubripes	25.49	1.00e-18	84.70
IUUC-Tsy-119599	Tarsius syrichta	23.35	2.00e-20	90.10
IUUC-Tni-120315	Tetraodon nigroviridis	25.49	9.00e-19	84.70
IUUC-Tca-121033	Theobroma cacao	25.71	7.00e-18	82.00
IUUC-Tre-121986	Trichoderma reesei	28.26	8.00e-15	72.00
IUUC-Tvi-122607	Trichoderma virens	27.31	1.00e-17	80.90
IUUC-Tae-125815	Triticum aestivum	24.65	1.00e-14	71.60
IUUC-Tur-126375	Triticum urartu	21.09	1.00e-10	58.90
IUUC-Tme-126878	Tuber melanosporum	27.56	4.00e-19	86.70
IUUC-Tbe-127429	Tupaia belangeri	30.73	5.00e-17	79.30
IUUC-Ttr-128467	Tursiops truncatus	30.28	2.00e-16	77.40
IUUC-Uma-129364	Ustilago maydis	24.35	2.00e-07	47.80
IUUC-Vda-129929	Verticillium dahliae	26.78	6.00e-13	66.20
IUUC-Vpa-130048	Vicugna pacos	23.20	2.00e-13	67.00
IUUC-Vvi-130834	Vitis vinifera	27.20	2.00e-19	87.40
IUUC-Xtr-131888	Xenopus tropicalis	23.74	3.00e-20	89.70
IUUC-Xma-133834	Xiphophorus maculatus	24.22	7.00e-20	88.60
IUUC-Yli-134595	Yarrowia lipolytica	28.12	9.00e-20	87.80
IUUC-Zma-135864	Zea mays	26.12	2.00e-20	90.10

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence