iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033242

UUCD1 version

UUC-EqC-00054

Ensembl Protein ID

ENSECAP00000018953.1

UniProt Accession

F6Q8L6; F6Q8L6_HORSE

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Gene Name

DCUN1D1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021365.1	ENSECAT00000022906.1	ENSECAP00000018953.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	1.20e-91	306.1	60	246
UBD/Alpha-Helix/UBA	3.90e-07	30.2	6	44

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselk 89
           ++kkle+l++rYkdpq++ +igi+g+++fc+dl++dp++i+vL++awk++aat+cefs++ef+dg+t+lgcdsiekl+++++++e+elk
   Q: 60   DRKKLEQLYNRYKDPQDEnKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELK 148
           78**************999********************************************************************** PP
   S: 90   deqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWP 178
           +  +fkd+Y+f+fnfak++gqk+ldl++aia+w+L+l++r fk+ld+w+kfL e++k+si+kDtWnllL+fs++ia+d+snYdeegaWP
   Q: 149  EPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGR-FKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWP 236
           ***************************************9.************************************************ PP
   S: 179  vliDefveyl 188
           vliD+fve++
   Q: 237  VLIDDFVEFA 246
           ********97 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlve.MGFdreealqaLraannnleaAveyLl 39
           +++dk++q++  +  ++++a+ +L ++++ l++A+++++
   Q: 6    SQKDKVRQFMIfTQSSEKTAVSCLSQNDWKLDVATDNFF 44
           699********9999999*******************99 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

NKLKSSQKDK VRQFMIFTQS SEKTAVSCLS QNDWKLDVAT DNFFQNPELY IRESVKGSLD 60
RKKLEQLYNR YKDPQDENKI GIDGIQQFCD DLALDPASIS VLIIAWKFRA ATQCEFSKQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAATAGAACA AGTTGAAATC ATCGCAGAAG GATAAAGTTC GTCAGTTTAT GATCTTCACA 60
CAATCTAGTG AAAAAACAGC AGTAAGTTGT CTGTCTCAAA ATGACTGGAA GTTAGATGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	43.09	2.00e-60	225.00
IUUC-Aml-001879	Ailuropoda melanoleuca	99.61	8.00e-153	532.00
IUUC-Atr-002662	Amborella trichopoda	38.69	5.00e-25	107.00
IUUC-Apl-003451	Anas platyrhynchos	97.70	2.00e-150	523.00
IUUC-Aca-005269	Anolis carolinensis	96.12	1.00e-148	518.00
IUUC-Aly-006285	Arabidopsis lyrata	37.40	4.00e-44	170.00
IUUC-Ath-007531	Arabidopsis thaliana	43.90	5.00e-58	217.00
IUUC-Ago-007806	Ashbya gossypii	23.74	4.00e-20	91.70
IUUC-Acl-008172	Aspergillus clavatus	27.38	5.00e-23	101.00
IUUC-Afl-008569	Aspergillus flavus	29.37	3.00e-29	121.00
IUUC-Ani-009241	Aspergillus nidulans	26.71	6.00e-25	107.00
IUUC-Ang-009664	Aspergillus niger	28.40	5.00e-24	104.00
IUUC-Ate-010414	Aspergillus terreus	30.23	1.00e-30	126.00
IUUC-Ame-011763	Astyanax mexicanus	88.76	2.00e-136	478.00
IUUC-Bgr-011991	Blumeria graminis	32.23	1.00e-25	110.00
IUUC-Bta-013561	Bos taurus	99.59	1.00e-144	505.00
IUUC-Bci-013824	Botrytis cinerea	32.68	6.00e-31	127.00
IUUC-Bdi-014138	Brachypodium distachyon	43.50	2.00e-61	228.00
IUUC-Bol-016110	Brassica oleracea	43.50	3.00e-57	214.00
IUUC-Bra-017111	Brassica rapa	43.50	4.00e-57	214.00
IUUC-Cel-018441	Caenorhabditis elegans	36.50	6.00e-51	194.00
IUUC-Cja-019502	Callithrix jacchus	99.61	1.00e-152	531.00
IUUC-Cfa-020523	Canis familiaris	100.00	2.00e-145	507.00
IUUC-Cpo-022196	Cavia porcellus	98.84	9.00e-152	528.00
IUUC-Cre-022620	Chlamydomonas reinhardtii	36.50	4.00e-50	191.00
IUUC-Csa-023551	Chlorocebus sabaeus	100.00	3.00e-153	533.00
IUUC-Cho-024373	Choloepus hoffmanni	98.06	5.00e-146	509.00
IUUC-Cin-025269	Ciona intestinalis	61.09	3.00e-99	353.00
IUUC-Csv-026372	Ciona savignyi	41.80	5.00e-51	194.00
IUUC-Cgl-026386	Colletotrichum gloeosporioides	28.80	3.00e-23	100.00
IUUC-Cne-026950	Cryptococcus neoformans	31.23	4.00e-30	124.00
IUUC-Dre-028247	Danio rerio	88.76	6.00e-137	479.00
IUUC-Dno-028974	Dasypus novemcinctus	100.00	3.00e-153	533.00
IUUC-Dor-030696	Dipodomys ordii	89.15	2.00e-132	464.00
IUUC-Dse-031365	Dothistroma septosporum	27.52	1.00e-25	110.00
IUUC-Dme-032197	Drosophila melanogaster	63.71	3.00e-92	331.00
IUUC-Ete-032371	Echinops telfairi	99.61	8.00e-153	532.00
IUUC-Eeu-035317	Erinaceus europaeus	99.61	7.00e-153	532.00
IUUC-Fca-036061	Felis catus	100.00	3.00e-153	534.00
IUUC-Fal-037372	Ficedula albicollis	97.70	3.00e-150	523.00
IUUC-Fox-037884	Fusarium oxysporum	31.54	4.00e-18	84.00
IUUC-Fso-038150	Fusarium solani	28.92	3.00e-20	92.40
IUUC-Gmo-038885	Gadus morhua	88.37	1.00e-136	478.00
IUUC-Gga-040935	Gallus gallus	98.84	6.00e-152	529.00
IUUC-Gac-041937	Gasterosteus aculeatus	87.98	3.00e-135	473.00
IUUC-Gma-043545	Glycine max	42.68	6.00e-58	217.00
IUUC-Ggo-044468	Gorilla gorilla	98.85	7.00e-151	525.00
IUUC-Hsa-046089	Homo sapiens	100.00	3.00e-153	533.00
IUUC-Hvu-047636	Hordeum vulgare	39.02	2.00e-22	98.60
IUUC-Itr-047902	Ictidomys tridecemlineatus	75.39	2.00e-120	424.00
IUUC-Kpa-049127	Komagataella pastoris	28.52	5.00e-22	97.80
IUUC-Lch-050600	Latimeria chalumnae	94.96	1.00e-147	514.00
IUUC-Lpe-051540	Leersia perrieri	44.31	1.00e-61	229.00
IUUC-Loc-052509	Lepisosteus oculatus	94.57	6.00e-145	506.00
IUUC-Lma-053103	Leptosphaeria maculans	31.18	2.00e-32	132.00
IUUC-Laf-053527	Loxodonta africana	99.22	1.00e-152	531.00
IUUC-Mcc-055699	Macaca mulatta	89.90	1.00e-146	512.00
IUUC-Meu-056626	Macropus eugenii	78.29	3.00e-112	397.00
IUUC-Mor-056909	Magnaporthe oryzae	28.72	3.00e-25	108.00
IUUC-Mpo-057299	Magnaporthe poae	25.00	2.00e-17	82.80
IUUC-Mtr-057964	Medicago truncatula	41.87	3.00e-57	214.00
IUUC-Mla-058990	Melampsora laricipopulina	28.62	9.00e-19	87.40
IUUC-Mga-059379	Meleagris gallopavo	98.71	2.00e-136	477.00
IUUC-Mvi-060312	Microbotryum violaceum	34.23	5.00e-42	164.00
IUUC-Mmr-060851	Microcebus murinus	100.00	6.00e-153	532.00
IUUC-Mdo-063074	Monodelphis domestica	99.61	1.00e-155	543.00
IUUC-Mmu-063954	Mus musculus	99.22	3.00e-152	530.00
IUUC-Mac-065016	Musa acuminata	44.44	3.00e-43	167.00
IUUC-Mpu-066870	Mustela putorius furo	100.00	2.00e-145	507.00
IUUC-Mlu-067701	Myotis lucifugus	99.61	2.00e-152	530.00
IUUC-Ncr-068780	Neurospora crassa	25.45	1.00e-23	103.00
IUUC-Nle-069291	Nomascus leucogenys	100.00	3.00e-153	533.00
IUUC-Opr-070265	Ochotona princeps	72.87	7.00e-96	343.00
IUUC-Ont-071408	Oreochromis niloticus	88.76	1.00e-135	475.00
IUUC-Oan-073031	Ornithorhynchus anatinus	99.61	1.00e-152	531.00
IUUC-Ocu-074648	Oryctolagus cuniculus	100.00	3.00e-153	533.00
IUUC-Oba-074993	Oryza barthii	44.31	1.00e-61	229.00
IUUC-Obr-076341	Oryza brachyantha	43.90	6.00e-62	230.00
IUUC-Ogl-077099	Oryza glaberrima	44.31	1.00e-61	229.00
IUUC-Ogu-078285	Oryza glumaepatula	43.90	2.00e-60	225.00
IUUC-Oin-079441	Oryza indica	44.31	1.00e-61	229.00
IUUC-Olo-081037	Oryza longistaminata	44.31	1.00e-61	229.00
IUUC-Ome-081357	Oryza meridionalis	44.31	1.00e-61	229.00
IUUC-Oni-082632	Oryza nivara	43.90	1.00e-61	229.00
IUUC-Opu-083351	Oryza punctata	43.97	1.00e-57	215.00
IUUC-Oru-084306	Oryza rufipogon	44.31	1.00e-61	229.00
IUUC-Osa-085307	Oryza sativa	44.31	1.00e-61	229.00
IUUC-Ola-086371	Oryzias latipes	84.11	4.00e-134	470.00
IUUC-Olu-087646	Ostreococcus lucimarinus	36.44	2.00e-44	172.00
IUUC-Oga-089015	Otolemur garnettii	99.61	1.00e-152	531.00
IUUC-Oar-090405	Ovis aries	99.61	1.00e-152	531.00
IUUC-Ptr-090735	Pan troglodytes	100.00	3.00e-153	533.00
IUUC-Pan-092186	Papio anubis	99.23	9.00e-150	522.00
IUUC-Psi-093110	Pelodiscus sinensis	99.18	2.00e-143	501.00
IUUC-Pno-095145	Phaeosphaeria nodorum	32.54	6.00e-25	107.00
IUUC-Ppa-095306	Physcomitrella patens	43.15	4.00e-58	217.00
IUUC-Pfo-096813	Poecilia formosa	83.78	3.00e-132	464.00
IUUC-Pca-100218	Procavia capensis	96.12	8.00e-150	522.00
IUUC-Ppe-102032	Prunus persica	43.95	9.00e-61	226.00
IUUC-Pva-102983	Pteropus vampyrus	94.19	5.00e-139	486.00
IUUC-Pgr-103633	Puccinia graminis	27.53	9.00e-25	107.00
IUUC-Ptt-103979	Puccinia triticina	38.81	2.00e-04	40.00
IUUC-Pyt-104428	Pyrenophora triticirepentis	31.02	1.00e-29	123.00
IUUC-Rno-105554	Rattus norvegicus	98.84	1.00e-152	531.00
IUUC-Sce-106358	Saccharomyces cerevisiae	25.37	4.00e-20	91.70
IUUC-Sha-106888	Sarcophilus harrisii	99.61	5.00e-153	533.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	30.65	4.00e-23	101.00
IUUC-Spo-108207	Schizosaccharomyces pombe	32.46	7.00e-25	107.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	33.33	1.00e-32	132.00
IUUC-Smo-108750	Selaginella moellendorffii	42.28	5.00e-50	190.00
IUUC-Sit-110052	Setaria italica	43.15	1.00e-61	229.00
IUUC-Sly-111489	Solanum lycopersicum	44.72	3.00e-60	224.00
IUUC-Stu-112517	Solanum tuberosum	43.72	2.00e-59	222.00
IUUC-Sar-113509	Sorex araneus	75.58	1.00e-106	379.00
IUUC-Sbi-114113	Sorghum bicolor	43.15	1.00e-61	229.00
IUUC-Sre-115221	Sporisorium reilianum	27.74	1.00e-25	109.00
IUUC-Ssc-115547	Sus scrofa	100.00	3.00e-153	533.00
IUUC-Tgu-117147	Taeniopygia guttata	98.84	6.00e-152	529.00
IUUC-Tru-117740	Takifugu rubripes	86.05	2.00e-133	467.00
IUUC-Tsy-119599	Tarsius syrichta	99.61	9.00e-153	531.00
IUUC-Tni-120315	Tetraodon nigroviridis	81.25	3.00e-130	457.00
IUUC-Tca-121033	Theobroma cacao	43.90	6.00e-59	220.00
IUUC-Tre-121986	Trichoderma reesei	25.96	2.00e-19	89.40
IUUC-Tvi-122607	Trichoderma virens	28.95	7.00e-26	110.00
IUUC-Tae-125740	Triticum aestivum	36.93	2.00e-54	205.00
IUUC-Tur-126375	Triticum urartu	34.38	1.00e-50	193.00
IUUC-Tme-126878	Tuber melanosporum	33.60	4.00e-39	155.00
IUUC-Ttr-129086	Tursiops truncatus	89.15	2.00e-132	464.00
IUUC-Uma-129364	Ustilago maydis	29.70	3.00e-34	138.00
IUUC-Vda-129929	Verticillium dahliae	29.29	1.00e-19	90.50
IUUC-Vpa-130048	Vicugna pacos	86.82	7.00e-128	449.00
IUUC-Vvi-130834	Vitis vinifera	44.31	1.00e-59	223.00
IUUC-Xtr-131888	Xenopus tropicalis	98.45	2.00e-151	527.00
IUUC-Xma-133580	Xiphophorus maculatus	84.11	6.00e-134	469.00
IUUC-Yli-134595	Yarrowia lipolytica	32.51	4.00e-36	144.00
IUUC-Zma-135642	Zea mays	44.08	2.00e-61	228.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence