iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002368

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01100946

Gene Name

WDR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000005656.1	ENSAMET00000006258.1	ENSAMEP00000006010.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-39	132.2	251	281
UBD/Beta-Prp	8.30e-61	205.8	74	295

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H ++++++++ +d t+l+s+s+D+t k+WD+
   Q: 251  HDGGIYAISWsPDsTHLLSASGDKTSKIWDV 281
           99*********999****************7 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl..sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           +h +++ + k++p++ ++a+g  +g++++wd+t++  l ++  +   ++++++ + +d+k ++ ++e   ++  v+  ++g+ v  ++g
   Q: 74   EHAHQVVVAKYAPSGFYIASGDVSGKLRIWDTTQKEHLLKYeyQPFAGKIKDIAWTEDSKRIAVVGEGreKFGAVFLWDSGSSVGEITG 162
           455666678*************************998777742334567***********99999999887777777789********* PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgg 178
           h++ + s+++ +s+ ++l++Gs+d+ +  ++ +  +    t   h ++vncv+++pdgn ++++s+D+++ ++d ktg+ +  l   ++
   Q: 163  HNKVINSVDIKQSRpYRLATGSDDNCAAFFEGPPFKFKF-TIGDHGRFVNCVRFSPDGNRFATASADGQIYVYDGKTGEKVCALggGKA 250
           ************999*****************9999998.99******************************************99556 PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtd 223
           h++ +y +s+++++++l+s+s d+t k+wd+  +++v t++  ++
   Q: 251  HDGGIYAISWSPDSTHLLSASGDKTSKIWDVNVNSVVSTFTMGST 295
           **************************************9986554 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

SPQPGRGQQG AATNAPRLVC VSAEKVFASL PQVERGVSKI IGGDPKGNNF IYTNGKCVIL 60
RNIDNPALAD IYTEHAHQVV VAKYAPSGFY IASGDVSGKL RIWDTTQKEH LLKYEYQPFA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCCTCAGC CCGGCCGGGG GCAGCAGGGG GCTGCCACTA ACGCGCCTCG CTTGGTTTGT 60
GTCTCCGCAG AGAAGGTGTT CGCCAGCCTC CCCCAGGTGG AGAGGGGCGT CTCCAAAATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011045--N2O_reductase_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0030043--P:actin filament fragmentation
GO:0043297--P:apical junction assembly
GO:0030865--P:cortical cytoskeleton organization
GO:0042247--P:establishment of planar polarity of follicular epithelium
GO:0045199--P:maintenance of epithelial cell apical/basal polarity
GO:0002446--P:neutrophil mediated immunity
GO:1990266--P:neutrophil migration
GO:0030220--P:platelet formation
GO:0030836--P:positive regulation of actin filament depolymerization
GO:0008360--P:regulation of cell shape
GO:0060307--P:regulation of ventricular cardiac muscle cell membrane repolarization
GO:0045214--P:sarcomere organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	35.27	8.00e-82	297.00
IUUC-Atr-003160	Amborella trichopoda	36.82	2.00e-113	403.00
IUUC-Apl-004012	Anas platyrhynchos	85.51	0.00e+00	1071.00
IUUC-Aca-004707	Anolis carolinensis	83.03	0.00e+00	1043.00
IUUC-Aly-006465	Arabidopsis lyrata	37.09	5.00e-109	388.00
IUUC-Ath-006740	Arabidopsis thaliana	36.93	9.00e-108	384.00
IUUC-Ago-007920	Ashbya gossypii	28.41	2.00e-74	273.00
IUUC-Acl-008262	Aspergillus clavatus	36.59	8.00e-108	384.00
IUUC-Afl-008471	Aspergillus flavus	33.78	6.00e-80	291.00
IUUC-Afu-008989	Aspergillus fumigatus	38.60	1.00e-97	350.00
IUUC-Ani-009167	Aspergillus nidulans	37.87	4.00e-116	411.00
IUUC-Ang-009595	Aspergillus niger	37.67	1.00e-104	374.00
IUUC-Aor-009908	Aspergillus oryzae	36.99	7.00e-104	371.00
IUUC-Ate-010580	Aspergillus terreus	37.09	3.00e-109	390.00
IUUC-Ame-011269	Astyanax mexicanus	60.40	5.00e-135	474.00
IUUC-Bgr-011996	Blumeria graminis	34.75	2.00e-107	382.00
IUUC-Bta-013278	Bos taurus	95.51	0.00e+00	1199.00
IUUC-Bci-013925	Botrytis cinerea	35.83	8.00e-109	387.00
IUUC-Bdi-014659	Brachypodium distachyon	35.75	1.00e-103	370.00
IUUC-Bol-016043	Brassica oleracea	35.63	2.00e-106	380.00
IUUC-Bra-017139	Brassica rapa	35.88	7.00e-108	384.00
IUUC-Cel-018417	Caenorhabditis elegans	40.46	7.00e-123	434.00
IUUC-Cja-019952	Callithrix jacchus	96.34	0.00e+00	1159.00
IUUC-Cfa-020225	Canis familiaris	97.50	0.00e+00	1193.00
IUUC-Cpo-021900	Cavia porcellus	94.84	0.00e+00	1173.00
IUUC-Csa-023028	Chlorocebus sabaeus	97.00	0.00e+00	1163.00
IUUC-Cho-025030	Choloepus hoffmanni	68.33	0.00e+00	756.00
IUUC-Cin-025152	Ciona intestinalis	55.29	3.00e-81	294.00
IUUC-Csv-025986	Ciona savignyi	37.63	5.00e-93	334.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	38.27	3.00e-112	399.00
IUUC-Cne-026814	Cryptococcus neoformans	34.35	1.00e-95	343.00
IUUC-Dre-027498	Danio rerio	80.00	9.00e-93	332.00
IUUC-Dno-029383	Dasypus novemcinctus	95.17	0.00e+00	1142.00
IUUC-Dor-030633	Dipodomys ordii	94.30	0.00e+00	1092.00
IUUC-Dse-031526	Dothistroma septosporum	38.55	7.00e-119	421.00
IUUC-Dme-031597	Drosophila melanogaster	47.05	1.00e-166	579.00
IUUC-Ete-032780	Echinops telfairi	85.19	0.00e+00	1033.00
IUUC-Eca-034306	Equus caballus	95.34	0.00e+00	1157.00
IUUC-Eeu-034531	Erinaceus europaeus	74.45	2.00e-136	479.00
IUUC-Fca-036301	Felis catus	97.67	0.00e+00	1222.00
IUUC-Fal-037361	Ficedula albicollis	88.58	0.00e+00	1129.00
IUUC-Fox-037924	Fusarium oxysporum	35.66	6.00e-103	368.00
IUUC-Fso-038199	Fusarium solani	34.95	3.00e-99	355.00
IUUC-Gmo-039238	Gadus morhua	71.81	0.00e+00	887.00
IUUC-Ggr-039830	Gaeumannomyces graminis	35.33	1.00e-96	347.00
IUUC-Gga-040235	Gallus gallus	89.02	0.00e+00	1100.00
IUUC-Gac-042363	Gasterosteus aculeatus	72.26	0.00e+00	921.00
IUUC-Gma-044189	Glycine max	36.95	7.00e-112	397.00
IUUC-Ggo-044632	Gorilla gorilla	94.52	0.00e+00	1127.00
IUUC-Hsa-045792	Homo sapiens	96.51	0.00e+00	1181.00
IUUC-Hvu-047517	Hordeum vulgare	35.30	2.00e-107	383.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	96.69	0.00e+00	1187.00
IUUC-Kpa-049183	Komagataella pastoris	32.68	4.00e-85	308.00
IUUC-Lch-050428	Latimeria chalumnae	75.37	0.00e+00	997.00
IUUC-Lpe-051306	Leersia perrieri	35.90	2.00e-108	386.00
IUUC-Loc-052096	Lepisosteus oculatus	72.18	0.00e+00	893.00
IUUC-Lma-053313	Leptosphaeria maculans	38.99	2.00e-117	418.00
IUUC-Laf-054060	Loxodonta africana	93.18	0.00e+00	1134.00
IUUC-Mcc-055619	Macaca mulatta	95.53	0.00e+00	1145.00
IUUC-Meu-056689	Macropus eugenii	77.35	2.00e-178	619.00
IUUC-Mor-056940	Magnaporthe oryzae	35.01	9.00e-98	350.00
IUUC-Mpo-057557	Magnaporthe poae	28.53	3.00e-58	219.00
IUUC-Mtr-057922	Medicago truncatula	35.61	1.00e-108	387.00
IUUC-Mla-059103	Melampsora laricipopulina	33.45	5.00e-77	281.00
IUUC-Mga-060150	Meleagris gallopavo	89.52	0.00e+00	1102.00
IUUC-Mvi-060448	Microbotryum violaceum	31.50	4.00e-74	272.00
IUUC-Mmr-061226	Microcebus murinus	94.68	0.00e+00	1148.00
IUUC-Mdo-062674	Monodelphis domestica	91.68	0.00e+00	1137.00
IUUC-Mmu-064170	Mus musculus	95.01	0.00e+00	1171.00
IUUC-Mac-065124	Musa acuminata	37.66	4.00e-112	398.00
IUUC-Mpu-066001	Mustela putorius furo	93.91	0.00e+00	1172.00
IUUC-Mlu-067253	Myotis lucifugus	95.01	0.00e+00	1180.00
IUUC-Nfi-068550	Neosartorya fischeri	38.25	6.00e-111	394.00
IUUC-Ncr-068948	Neurospora crassa	36.29	1.00e-113	403.00
IUUC-Nle-070115	Nomascus leucogenys	93.85	0.00e+00	1076.00
IUUC-Opr-070254	Ochotona princeps	93.33	0.00e+00	1109.00
IUUC-Ont-071666	Oreochromis niloticus	75.54	0.00e+00	950.00
IUUC-Oan-073594	Ornithorhynchus anatinus	92.49	1.00e-168	585.00
IUUC-Ocu-074824	Oryctolagus cuniculus	94.68	0.00e+00	1130.00
IUUC-Oba-075010	Oryza barthii	36.29	2.00e-109	389.00
IUUC-Obr-076364	Oryza brachyantha	37.36	1.00e-110	394.00
IUUC-Ogl-077019	Oryza glaberrima	36.29	2.00e-109	389.00
IUUC-Ogu-078496	Oryza glumaepatula	36.29	2.00e-109	389.00
IUUC-Oin-080116	Oryza indica	36.45	1.00e-109	390.00
IUUC-Olo-080290	Oryza longistaminata	36.29	5.00e-109	388.00
IUUC-Ome-081969	Oryza meridionalis	36.29	3.00e-109	389.00
IUUC-Oni-082075	Oryza nivara	36.29	2.00e-109	389.00
IUUC-Opu-083959	Oryza punctata	36.33	2.00e-109	389.00
IUUC-Oru-084711	Oryza rufipogon	36.29	2.00e-109	389.00
IUUC-Osa-085958	Oryza sativa	36.45	1.00e-109	390.00
IUUC-Ola-086968	Oryzias latipes	75.99	0.00e+00	965.00
IUUC-Oga-089108	Otolemur garnettii	92.69	0.00e+00	1201.00
IUUC-Oar-089986	Ovis aries	89.68	0.00e+00	1135.00
IUUC-Ptr-091281	Pan troglodytes	96.83	0.00e+00	1185.00
IUUC-Pan-092585	Papio anubis	97.17	0.00e+00	1166.00
IUUC-Psi-093811	Pelodiscus sinensis	87.52	0.00e+00	1125.00
IUUC-Pma-094542	Petromyzon marinus	69.72	0.00e+00	891.00
IUUC-Pno-095086	Phaeosphaeria nodorum	37.04	1.00e-109	390.00
IUUC-Ppa-095876	Physcomitrella patens	36.14	7.00e-111	394.00
IUUC-Pfo-096973	Poecilia formosa	75.79	0.00e+00	981.00
IUUC-Pab-098391	Pongo abelii	96.51	0.00e+00	1163.00
IUUC-Pop-098850	Populus trichocarpa	36.62	2.00e-109	389.00
IUUC-Pca-100257	Procavia capensis	60.26	4.00e-91	328.00
IUUC-Ppe-101578	Prunus persica	37.27	8.00e-112	397.00
IUUC-Pva-102872	Pteropus vampyrus	90.86	0.00e+00	1127.00
IUUC-Pgr-103593	Puccinia graminis	32.33	1.00e-78	287.00
IUUC-Pte-104365	Pyrenophora teres	39.32	1.00e-112	400.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	39.00	3.00e-115	408.00
IUUC-Rno-105737	Rattus norvegicus	95.51	0.00e+00	1202.00
IUUC-Sce-106383	Saccharomyces cerevisiae	29.61	5.00e-70	258.00
IUUC-Sha-107084	Sarcophilus harrisii	90.02	0.00e+00	1013.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	36.11	2.00e-111	395.00
IUUC-Spo-108309	Schizosaccharomyces pombe	33.77	9.00e-96	344.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	35.50	5.00e-108	385.00
IUUC-Smo-109255	Selaginella moellendorffii	35.52	2.00e-100	359.00
IUUC-Sit-109962	Setaria italica	37.50	1.00e-111	397.00
IUUC-Sly-110897	Solanum lycopersicum	37.87	3.00e-114	405.00
IUUC-Stu-111971	Solanum tuberosum	37.70	4.00e-113	402.00
IUUC-Sar-113415	Sorex araneus	73.06	1.00e-110	393.00
IUUC-Sbi-114857	Sorghum bicolor	36.95	1.00e-109	390.00
IUUC-Sre-114900	Sporisorium reilianum	34.00	3.00e-91	329.00
IUUC-Tgu-117256	Taeniopygia guttata	88.52	0.00e+00	1129.00
IUUC-Tru-117871	Takifugu rubripes	71.05	0.00e+00	889.00
IUUC-Tsy-119172	Tarsius syrichta	97.50	7.00e-139	487.00
IUUC-Tni-120339	Tetraodon nigroviridis	71.05	0.00e+00	922.00
IUUC-Tca-121609	Theobroma cacao	36.25	3.00e-110	392.00
IUUC-Tre-122076	Trichoderma reesei	35.65	2.00e-95	343.00
IUUC-Tvi-122528	Trichoderma virens	34.20	3.00e-97	349.00
IUUC-Tae-124549	Triticum aestivum	35.63	2.00e-108	385.00
IUUC-Tur-126845	Triticum urartu	35.25	5.00e-81	295.00
IUUC-Tme-127217	Tuber melanosporum	35.10	1.00e-102	367.00
IUUC-Tbe-127526	Tupaia belangeri	93.19	0.00e+00	1150.00
IUUC-Ttr-128898	Tursiops truncatus	87.54	0.00e+00	1083.00
IUUC-Uma-129631	Ustilago maydis	32.30	2.00e-94	339.00
IUUC-Vda-129732	Verticillium dahliae	35.34	1.00e-93	337.00
IUUC-Vvi-131217	Vitis vinifera	37.60	1.00e-110	393.00
IUUC-Xtr-132860	Xenopus tropicalis	74.18	0.00e+00	936.00
IUUC-Xma-133830	Xiphophorus maculatus	75.79	0.00e+00	981.00
IUUC-Yli-134335	Yarrowia lipolytica	32.90	5.00e-77	281.00
IUUC-Zma-135907	Zea mays	37.11	1.00e-110	394.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence