iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068948

Ensembl Protein ID

EAA28347

UniProt Accession

Q7RZB7; Q7RZB7_NEUCR

Genbank Protein ID

EAA28347.1

Protein Name

WD repeat containing protein 2

Genbank Nucleotide ID

CM002241

Gene Name

NCU03944

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU03944	EAA28347	EAA28347

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.60e-35	117.2	231	266
UBD/Beta-Prp	4.70e-68	228.6	183	428

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           Ht++++++++ sd +++v++s D t++vWD  +g+ 
   Q: 231  HTGGIYGISWaSDsKHFVTSSADQTVRVWDAESGKN 266
           9**********999****************888875 PP

UBD/Beta-Prp

   S: 47   slsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk..ghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.......tlsghdg 138
           + s+h+++vt + fspdg +lvt++ Dr i+++d +tg ++ t+    h+  ++ +s+  +++++v+ s+d+t+rvwd e+g+  e+         s+ d+
   Q: 183  KASEHKGFVTGTAFSPDGATLVTVGADRKIQLYDGKTGAPTKTIGegVHTGGIYGISWASDSKHFVTSSADQTVRVWDAESGKNTETwrfgpegSVSIPDQ 283
           6799****************************************9777**************************************999999997777777 PP
   S: 139  vvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq..tgecvrtlnghtdnvksvrfspnder 236
            v +v  h+ +  l++s  l++ +      + k +r  +g h++ ++ l  +++g+ l++gs  g+v  wdl   tg+ v+  + h+++v++ ++sp +  
   Q: 284  QVGVVWPHGRTdGLIISLNLNGDLSYLVPGNPKPIRVVQG-HNKNITALGASPDGQALLTGSFEGRVLSWDLAagTGT-VVDGQSHSNQVTQFALSPSGGT 382
           7777778887778999999999999777799999999999.*******************************966665.77888999************** PP
   S: 237  lvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgs 284
           ++s++ D ++r  d+  +++++  ++   +   +a+   +d ++v ++
   Q: 383  VYSVGWDDTLRSVDVSANTFTGLSTKLSAQPKGIAT--TSDGKFVVVA 428
           *****9999999999998888776665544444444..3444444444 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MPIEIDKILA AAPATTRGQA TQLSCDPKGE RIVYASGKSI FVRTIDEPSK SLQYTGHTTT 60
TTVARFSPSG FWVASGDVSG KVRVWDAVGA ENTKGEYSII SGRINDIAWD GDSQRVIAVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCCATCTA GCTGACACCG ATCTGACACC TTGGAACAGC TCCCCCTTGT TACGAGCTCC 60
CCCCAGCTGG GTTGATACCT TAGCCCCCTA CTGTGTATAA TAAACAAACG CCAACTCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030479--C:actin cortical patch
GO:0042643--C:actomyosin, actin portion
GO:0032153--C:cell division site
GO:0051286--C:cell tip
GO:0030864--C:cortical actin cytoskeleton
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0051015--F:actin filament binding
GO:0030042--P:actin filament depolymerization
GO:0051016--P:barbed-end actin filament capping
GO:0032466--P:negative regulation of cytokinesis
GO:0030836--P:positive regulation of actin filament depolymerization

KEGG

ncr:NCU03944

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000457	Aegilops tauschii	30.27	2.00e-59	221.00
IUUC-Aml-002368	Ailuropoda melanoleuca	35.99	1.00e-112	398.00
IUUC-Atr-003160	Amborella trichopoda	33.17	2.00e-88	318.00
IUUC-Apl-004012	Anas platyrhynchos	36.02	8.00e-108	382.00
IUUC-Aca-004707	Anolis carolinensis	36.60	4.00e-109	387.00
IUUC-Aly-006423	Arabidopsis lyrata	31.25	4.00e-86	310.00
IUUC-Ath-006829	Arabidopsis thaliana	32.31	1.00e-87	315.00
IUUC-Ago-007920	Ashbya gossypii	36.48	1.00e-97	348.00
IUUC-Acl-008262	Aspergillus clavatus	54.13	2.00e-180	624.00
IUUC-Afl-008471	Aspergillus flavus	37.98	3.00e-92	331.00
IUUC-Afu-008989	Aspergillus fumigatus	53.83	9.00e-166	575.00
IUUC-Ani-009167	Aspergillus nidulans	54.38	0.00e+00	641.00
IUUC-Ang-009595	Aspergillus niger	54.44	7.00e-172	595.00
IUUC-Aor-009908	Aspergillus oryzae	54.24	2.00e-172	597.00
IUUC-Ate-010580	Aspergillus terreus	54.71	2.00e-180	625.00
IUUC-Ame-011269	Astyanax mexicanus	32.87	1.00e-55	209.00
IUUC-Bgr-011996	Blumeria graminis	56.43	0.00e+00	683.00
IUUC-Bta-013278	Bos taurus	37.14	6.00e-116	409.00
IUUC-Bci-013925	Botrytis cinerea	60.93	0.00e+00	724.00
IUUC-Bdi-014659	Brachypodium distachyon	31.14	1.00e-79	288.00
IUUC-Bol-016043	Brassica oleracea	32.36	3.00e-88	317.00
IUUC-Bra-017719	Brassica rapa	32.10	2.00e-86	311.00
IUUC-Cel-018417	Caenorhabditis elegans	35.56	5.00e-97	346.00
IUUC-Cja-019952	Callithrix jacchus	36.35	1.00e-110	392.00
IUUC-Cfa-020225	Canis familiaris	36.83	7.00e-116	409.00
IUUC-Cpo-021900	Cavia porcellus	37.60	5.00e-112	396.00
IUUC-Csa-023028	Chlorocebus sabaeus	36.51	8.00e-111	392.00
IUUC-Cho-025030	Choloepus hoffmanni	35.64	3.00e-60	224.00
IUUC-Cin-025152	Ciona intestinalis	37.35	8.00e-52	194.00
IUUC-Csv-025986	Ciona savignyi	28.57	3.00e-54	204.00
IUUC-Cgl-026597	Colletotrichum gloeosporioides	68.44	0.00e+00	795.00
IUUC-Cne-026814	Cryptococcus neoformans	36.55	3.00e-96	343.00
IUUC-Dre-027498	Danio rerio	49.17	4.00e-50	188.00
IUUC-Dno-029383	Dasypus novemcinctus	37.62	1.00e-111	395.00
IUUC-Dor-030633	Dipodomys ordii	37.13	5.00e-104	370.00
IUUC-Dse-031526	Dothistroma septosporum	59.84	0.00e+00	702.00
IUUC-Dme-031597	Drosophila melanogaster	37.76	3.00e-121	426.00
IUUC-Ete-032780	Echinops telfairi	36.39	8.00e-105	372.00
IUUC-Eca-034306	Equus caballus	35.84	1.00e-109	388.00
IUUC-Eeu-034531	Erinaceus europaeus	55.77	4.00e-30	124.00
IUUC-Fca-036301	Felis catus	36.63	2.00e-114	404.00
IUUC-Fal-037361	Ficedula albicollis	36.74	6.00e-114	402.00
IUUC-Fox-037924	Fusarium oxysporum	59.03	0.00e+00	695.00
IUUC-Fso-038199	Fusarium solani	59.84	0.00e+00	714.00
IUUC-Gmo-039238	Gadus morhua	34.29	2.00e-102	364.00
IUUC-Ggr-039830	Gaeumannomyces graminis	66.67	0.00e+00	725.00
IUUC-Gga-040235	Gallus gallus	36.81	3.00e-112	397.00
IUUC-Gac-042363	Gasterosteus aculeatus	34.92	4.00e-105	373.00
IUUC-Gma-044189	Glycine max	34.40	1.00e-89	322.00
IUUC-Ggo-044632	Gorilla gorilla	36.29	7.00e-108	382.00
IUUC-Hsa-045792	Homo sapiens	36.35	7.00e-113	399.00
IUUC-Hvu-047517	Hordeum vulgare	32.80	1.00e-86	311.00
IUUC-Itr-048076	Ictidomys tridecemlineatus	37.26	2.00e-114	404.00
IUUC-Kpa-049183	Komagataella pastoris	42.16	5.00e-120	422.00
IUUC-Lch-050428	Latimeria chalumnae	35.24	4.00e-110	390.00
IUUC-Lpe-051306	Leersia perrieri	32.10	4.00e-88	317.00
IUUC-Loc-052096	Lepisosteus oculatus	32.54	8.00e-86	309.00
IUUC-Lma-053313	Leptosphaeria maculans	58.50	0.00e+00	680.00
IUUC-Laf-054060	Loxodonta africana	37.14	5.00e-111	393.00
IUUC-Mcc-055619	Macaca mulatta	36.22	2.00e-106	377.00
IUUC-Meu-056689	Macropus eugenii	39.05	8.00e-52	196.00
IUUC-Mor-056940	Magnaporthe oryzae	63.87	0.00e+00	689.00
IUUC-Mpo-057557	Magnaporthe poae	55.85	3.00e-165	572.00
IUUC-Mtr-058478	Medicago truncatula	33.87	9.00e-89	319.00
IUUC-Mla-059103	Melampsora laricipopulina	37.54	2.00e-92	331.00
IUUC-Mga-060150	Meleagris gallopavo	36.49	2.00e-110	391.00
IUUC-Mvi-060448	Microbotryum violaceum	40.00	7.00e-104	369.00
IUUC-Mmr-061226	Microcebus murinus	37.42	2.00e-110	391.00
IUUC-Mdo-062674	Monodelphis domestica	37.62	6.00e-117	412.00
IUUC-Mmu-064170	Mus musculus	37.62	9.00e-115	405.00
IUUC-Mac-065124	Musa acuminata	33.98	1.00e-92	332.00
IUUC-Mpu-066001	Mustela putorius furo	35.50	3.00e-110	390.00
IUUC-Mlu-067253	Myotis lucifugus	36.59	2.00e-109	387.00
IUUC-Nfi-068550	Neosartorya fischeri	55.22	0.00e+00	645.00
IUUC-Nle-070115	Nomascus leucogenys	35.87	5.00e-99	353.00
IUUC-Opr-070254	Ochotona princeps	36.83	1.00e-105	375.00
IUUC-Ont-071666	Oreochromis niloticus	35.37	3.00e-103	367.00
IUUC-Oan-073292	Ornithorhynchus anatinus	52.99	4.00e-39	151.00
IUUC-Ocu-074824	Oryctolagus cuniculus	36.88	8.00e-109	385.00
IUUC-Oba-075010	Oryza barthii	31.46	3.00e-86	310.00
IUUC-Obr-076364	Oryza brachyantha	32.26	4.00e-88	317.00
IUUC-Ogl-077019	Oryza glaberrima	31.46	3.00e-86	310.00
IUUC-Ogu-078496	Oryza glumaepatula	31.46	3.00e-86	310.00
IUUC-Oin-080116	Oryza indica	31.46	2.00e-86	311.00
IUUC-Olo-080290	Oryza longistaminata	31.57	6.00e-86	310.00
IUUC-Ome-081969	Oryza meridionalis	31.46	4.00e-86	310.00
IUUC-Oni-082075	Oryza nivara	31.30	1.00e-85	308.00
IUUC-Opu-083959	Oryza punctata	32.10	2.00e-87	315.00
IUUC-Oru-084711	Oryza rufipogon	31.46	3.00e-86	310.00
IUUC-Osa-085958	Oryza sativa	31.46	2.00e-86	311.00
IUUC-Ola-086968	Oryzias latipes	36.17	4.00e-111	393.00
IUUC-Oga-089108	Otolemur garnettii	36.84	5.00e-114	403.00
IUUC-Oar-089986	Ovis aries	34.72	2.00e-102	364.00
IUUC-Ptr-091281	Pan troglodytes	36.22	8.00e-111	392.00
IUUC-Pan-092585	Papio anubis	36.67	2.00e-111	394.00
IUUC-Psi-093811	Pelodiscus sinensis	35.60	2.00e-113	400.00
IUUC-Pma-094396	Petromyzon marinus	36.55	6.00e-114	402.00
IUUC-Pno-095086	Phaeosphaeria nodorum	57.07	0.00e+00	656.00
IUUC-Ppa-095876	Physcomitrella patens	33.44	4.00e-85	307.00
IUUC-Pfo-096973	Poecilia formosa	36.07	1.00e-112	398.00
IUUC-Pab-098391	Pongo abelii	36.67	4.00e-111	393.00
IUUC-Pop-098851	Populus trichocarpa	32.91	8.00e-86	309.00
IUUC-Pca-100257	Procavia capensis	52.38	7.00e-20	90.50
IUUC-Ppe-101578	Prunus persica	32.96	4.00e-88	317.00
IUUC-Pva-102872	Pteropus vampyrus	36.28	3.00e-112	397.00
IUUC-Pgr-103593	Puccinia graminis	36.57	8.00e-100	355.00
IUUC-Pte-104365	Pyrenophora teres	59.32	0.00e+00	661.00
IUUC-Pyt-104689	Pyrenophora triticirepentis	59.32	0.00e+00	675.00
IUUC-Rno-105737	Rattus norvegicus	37.30	1.00e-117	415.00
IUUC-Sce-106383	Saccharomyces cerevisiae	36.38	1.00e-99	355.00
IUUC-Sha-107084	Sarcophilus harrisii	35.88	2.00e-98	350.00
IUUC-Sja-107688	Schizosaccharomyces japonicus	41.52	7.00e-138	482.00
IUUC-Spo-108309	Schizosaccharomyces pombe	42.63	4.00e-131	459.00
IUUC-Ssl-108408	Sclerotinia sclerotiorum	61.25	0.00e+00	725.00
IUUC-Smo-109383	Selaginella moellendorffii	31.65	1.00e-79	289.00
IUUC-Sit-109962	Setaria italica	32.91	7.00e-89	319.00
IUUC-Sly-110897	Solanum lycopersicum	32.74	3.00e-89	320.00
IUUC-Stu-111971	Solanum tuberosum	32.58	2.00e-89	321.00
IUUC-Sar-113415	Sorex araneus	32.73	3.00e-39	154.00
IUUC-Sbi-114857	Sorghum bicolor	33.28	1.00e-89	322.00
IUUC-Sre-114900	Sporisorium reilianum	39.94	1.00e-114	404.00
IUUC-Tgu-117256	Taeniopygia guttata	37.24	3.00e-114	403.00
IUUC-Tru-117871	Takifugu rubripes	35.32	2.00e-108	384.00
IUUC-Tsy-119172	Tarsius syrichta	46.77	2.00e-58	218.00
IUUC-Tni-120339	Tetraodon nigroviridis	36.55	1.00e-111	395.00
IUUC-Tca-121563	Theobroma cacao	33.55	7.00e-90	323.00
IUUC-Tre-122076	Trichoderma reesei	55.92	0.00e+00	640.00
IUUC-Tvi-122528	Trichoderma virens	56.63	0.00e+00	684.00
IUUC-Tae-123530	Triticum aestivum	33.17	1.00e-87	315.00
IUUC-Tur-126845	Triticum urartu	29.60	2.00e-55	208.00
IUUC-Tme-127217	Tuber melanosporum	50.64	4.00e-163	566.00
IUUC-Tbe-127526	Tupaia belangeri	35.69	9.00e-107	379.00
IUUC-Ttr-128898	Tursiops truncatus	34.83	2.00e-101	361.00
IUUC-Uma-129631	Ustilago maydis	41.22	2.00e-125	441.00
IUUC-Vda-129732	Verticillium dahliae	55.85	0.00e+00	629.00
IUUC-Vvi-131217	Vitis vinifera	32.42	3.00e-86	310.00
IUUC-Xtr-132860	Xenopus tropicalis	32.54	8.00e-96	342.00
IUUC-Xma-133830	Xiphophorus maculatus	36.07	5.00e-113	399.00
IUUC-Yli-134335	Yarrowia lipolytica	38.61	8.00e-102	362.00
IUUC-Zma-135907	Zea mays	32.58	2.00e-87	315.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence