iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066017

Ensembl Protein ID

ENSMPUP00000001619.1

UniProt Accession

M3XRB9; M3XRB9_MUSPF

Genbank Protein ID

ENSMPUP00000001619

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01060960

Gene Name

UBA6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000001636.1	ENSMPUT00000001653.1	ENSMPUP00000001619.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.40e-221	735.2	443	930

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv......gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealke 83
           YD +++++G++ ++kl++ +++lvG+g++GcE+lKn++l+Gv      g++tv+D d +e+snlnrqFLfr+++++k+K+ +aa+a  +
   Q: 443  YDALRACIGDTLCQKLQKLNIFLVGCGAIGCEMLKNFALLGVgtgkekGMVTVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAADATLK 531
           9**************************************************************************************** PP
   S: 84   lnpdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqk 169
           +np+ +++ah +++++ +e i+   F++k d++++aldn+earr+v+++cl++ +pl++sgt+G++G+++vi+++lte+y++++dpp++
   Q: 532  INPQLKIDAHLNKVCPATEAIYndeFYTKQDIIITALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEE 620
           ***************************************************************************************** PP
   S: 170  tiPfctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafa 246
           +iPfctlk++p+a+ehti+wa            +lfnk++++++++eevl+kl++ +++eg+++v  +l s++++n+++++e+a+ +f+
   Q: 621  EIPFCTLKSFPAAIEHTIQWArdkfessfshkpSLFNKFWQTYPSAEEVLQKLQTGHSLEGCFQV-IKLLSRRPRNWSQCVELARLKFE 708
           *****************************************************************.999******************** PP
   S: 247  kttinsikqllksfecdivtkskspfwv.........................................................sfcs 278
           k++++++ qll++f+ d + k++s fw+                                                         +f +
   Q: 709  KYFNHKALQLLHCFPLDTRLKDGSLFWQspkrppspikfdlneplhfsfllnaaklyaavyciplteedlsadallnilsevkiqEFRP 797
           ***************************************************************************************** PP
   S: 279  naealqvpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlike 360
            ++ +q++e++ k+e+v  +s++     ++l++++ ++ ++ +++++++lsfekddd+  ++d++taa+nlra++++iep +d++++k+
   Q: 798  SNKVVQTDETARKPEHVPISSEDernavFQLEKAISSNKATSSDLQMAVLSFEKDDDHngHIDFITAASNLRAKMYSIEP-ADRFKTKR 885
           ******************999999********************************************************.******** PP
   S: 361  iagniipaiattnavvgGlaaqEviKvvsg.kfeplknfflfdae 404
           iag+iipaiat +a+v+Gl+a+E+iKv+   +fe++kn+fl++a+
   Q: 886  IAGKIIPAIATSTAAVSGLVALEMIKVAGDyPFEAYKNCFLNLAI 930
           *****************************************9886 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MEASEPVAAP QREEASCSSW GAVSTNTNLP IISAESVEID DALYSRQRYV LGDTAMQKMA 60
KSHVFLSGMG GLGLEIAKNL VLAGIKALTI HDTEKCQMWD LGTNFFLCED DVVNMRNRAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGCGT CCGAGCCGGT GGCCGCACCT CAGAGGGAAG AGGCGTCCTG CTCGTCCTGG 60
GGGGCCGTCA GGTGAGAGGA GGAGTGTGAG CGCGAAGCAG CGAGGGGTGG CGGCCGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR000011--UBQ/SUMO-activ_enz_E1-like

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019780--F:FAT10 activating enzyme activity
GO:0004839--F:ubiquitin activating enzyme activity
GO:0021764--P:amygdala development
GO:0060996--P:dendritic spine development
GO:0021766--P:hippocampus development
GO:0007612--P:learning
GO:0007626--P:locomotory behavior
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001608	Ailuropoda melanoleuca	96.29	0.00e+00	2112.00
IUUC-Apl-004158	Anas platyrhynchos	80.19	0.00e+00	1733.00
IUUC-Aca-005349	Anolis carolinensis	80.12	0.00e+00	1762.00
IUUC-Bta-012696	Bos taurus	92.40	0.00e+00	2046.00
IUUC-Cja-019563	Callithrix jacchus	92.30	0.00e+00	2011.00
IUUC-Cfa-020951	Canis familiaris	95.91	0.00e+00	2113.00
IUUC-Cpo-022307	Cavia porcellus	87.64	0.00e+00	1921.00
IUUC-Csa-023647	Chlorocebus sabaeus	92.49	0.00e+00	2023.00
IUUC-Cho-024682	Choloepus hoffmanni	76.91	0.00e+00	933.00
IUUC-Dre-028022	Danio rerio	66.60	0.00e+00	1472.00
IUUC-Dno-029796	Dasypus novemcinctus	91.05	0.00e+00	1950.00
IUUC-Dor-030981	Dipodomys ordii	76.39	0.00e+00	1531.00
IUUC-Ete-032514	Echinops telfairi	78.42	0.00e+00	1151.00
IUUC-Eca-033697	Equus caballus	93.59	0.00e+00	2026.00
IUUC-Eeu-035323	Erinaceus europaeus	84.54	0.00e+00	1369.00
IUUC-Fca-035858	Felis catus	96.02	0.00e+00	2078.00
IUUC-Fal-036848	Ficedula albicollis	80.51	0.00e+00	1734.00
IUUC-Gmo-039326	Gadus morhua	66.34	0.00e+00	1386.00
IUUC-Gga-040747	Gallus gallus	80.71	0.00e+00	1725.00
IUUC-Gac-041406	Gasterosteus aculeatus	67.09	0.00e+00	1402.00
IUUC-Ggo-044577	Gorilla gorilla	92.40	0.00e+00	2023.00
IUUC-Hsa-046007	Homo sapiens	92.21	0.00e+00	2013.00
IUUC-Itr-048191	Ictidomys tridecemlineatus	93.63	0.00e+00	1056.00
IUUC-Lch-049992	Latimeria chalumnae	74.39	0.00e+00	1560.00
IUUC-Loc-051899	Lepisosteus oculatus	68.79	0.00e+00	1497.00
IUUC-Laf-054413	Loxodonta africana	92.31	0.00e+00	1870.00
IUUC-Mcc-054656	Macaca mulatta	92.49	0.00e+00	2021.00
IUUC-Meu-056463	Macropus eugenii	72.25	0.00e+00	1427.00
IUUC-Mga-059721	Meleagris gallopavo	80.41	0.00e+00	1631.00
IUUC-Mmr-060908	Microcebus murinus	89.16	0.00e+00	1961.00
IUUC-Mdo-062096	Monodelphis domestica	84.96	0.00e+00	1900.00
IUUC-Mmu-064114	Mus musculus	90.02	0.00e+00	1982.00
IUUC-Mlu-068037	Myotis lucifugus	90.93	0.00e+00	1972.00
IUUC-Nle-069494	Nomascus leucogenys	91.63	0.00e+00	2002.00
IUUC-Opr-070910	Ochotona princeps	65.60	1.00e-171	597.00
IUUC-Ont-071592	Oreochromis niloticus	67.97	0.00e+00	1442.00
IUUC-Oan-073268	Ornithorhynchus anatinus	80.20	0.00e+00	1600.00
IUUC-Ocu-074296	Oryctolagus cuniculus	92.59	0.00e+00	2031.00
IUUC-Ola-086376	Oryzias latipes	68.76	0.00e+00	1412.00
IUUC-Oga-088186	Otolemur garnettii	90.68	0.00e+00	1985.00
IUUC-Oar-089307	Ovis aries	92.68	0.00e+00	2051.00
IUUC-Ptr-090609	Pan troglodytes	92.49	0.00e+00	2018.00
IUUC-Pan-092905	Papio anubis	92.07	0.00e+00	1925.00
IUUC-Psi-093489	Pelodiscus sinensis	81.88	0.00e+00	1763.00
IUUC-Pma-094203	Petromyzon marinus	68.24	3.00e-58	217.00
IUUC-Pfo-096670	Poecilia formosa	69.08	0.00e+00	1467.00
IUUC-Pab-098418	Pongo abelii	92.21	0.00e+00	2009.00
IUUC-Pca-100889	Procavia capensis	75.57	0.00e+00	1593.00
IUUC-Pva-103144	Pteropus vampyrus	82.03	0.00e+00	1765.00
IUUC-Rno-105612	Rattus norvegicus	89.73	0.00e+00	1976.00
IUUC-Sha-107388	Sarcophilus harrisii	86.81	0.00e+00	1882.00
IUUC-Sar-113128	Sorex araneus	89.19	0.00e+00	1937.00
IUUC-Ssc-116117	Sus scrofa	93.26	0.00e+00	2057.00
IUUC-Tgu-116565	Taeniopygia guttata	81.02	0.00e+00	1750.00
IUUC-Tru-118591	Takifugu rubripes	67.45	0.00e+00	1424.00
IUUC-Tsy-119436	Tarsius syrichta	79.85	0.00e+00	1712.00
IUUC-Tni-120880	Tetraodon nigroviridis	67.02	0.00e+00	1407.00
IUUC-Tbe-127714	Tupaia belangeri	79.54	0.00e+00	1405.00
IUUC-Ttr-129159	Tursiops truncatus	81.37	0.00e+00	1729.00
IUUC-Vpa-130716	Vicugna pacos	91.06	0.00e+00	1912.00
IUUC-Xtr-132947	Xenopus tropicalis	70.83	0.00e+00	1543.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence