iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033216

UUCD1 version

UUC-EqC-01075

Ensembl Protein ID

ENSECAP00000014115.1

UniProt Accession

F6XR25; F6XR25_HORSE

Protein Name

Uncharacterized protein

Gene Name

USP53

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000016383.1	ENSECAT00000017379.1	ENSECAP00000014115.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.10e-23	82.7	31	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaee...fs 85
           Gl N   +N+C++NS++Q+L+++  +r+ l   + + ++ +      +++ ++l++ f+++++s++ka    ++ +al++  +    f+
   Q: 31   GLLNEpgQNSCFLNSAVQVLWQLDIFRRSLRVLTGHVCQGD------ACIFCALKTTFAQFQHSREKALPSDNIRHALAESFKDeqrFQ 113
           55555447************************777777765......7*************9999999999987777776543222399 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
                Da E+++ +l++++ ++                     +++ +  ++++++ ++ F ++l +q++c +c+ +s    pf+++  
   Q: 114  LGLMDDAAECFENILEKIHFHI-------------------VPSRDADMCTSKSCITHQKFAMTLYEQCVCRSCGASSDPL-PFTEFVR 182
           **********************...................12235678999***********************999554.7888888 PP
   S: 175  pvpgkeetkke........slq.dcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkve 254
            ++    +++          l+ +++++  ++ + +++ +   ++c +k + ++   l ++Pe+ ++ L +   se+ +  e + +++ 
   Q: 183  YISTTALCNEVermierheRLKpEMFAELLQAANTTDDYRKCPSNCGQKIKIRRV--LMNCPEIVTIGLVWD--SEHSDLTEDVVRNLA 267
           8886665544455666666555378899999999998888888899988865554..6688**********9..444455555555555 PP
   S: 255  fpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...staYvlfYk 336
           + l L    + +++e+  +++ +  L++++++       HY+a++ ++k + W+ fdD +V+ev  ++++v++++     ++ +lfY 
   Q: 268  THLYLPGLFYRVTDEN--AKSSELHLVGMICYAS----RHYCAFAFHTKSSkWVFFDDANVKEVgtRWKDVVSKCIrchFQPLLLFYA 349
           5433333333334333..348999********87....9********77767***********9656899999766888899999996 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAWVKFLRKP GGNLGKVYQP GSMLSLAPTK GLLNEPGQNS CFLNSAVQVL WQLDIFRRSL 60
RVLTGHVCQG DACIFCALKT TFAQFQHSRE KALPSDNIRH ALAESFKDEQ RFQLGLMDDA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTATCATC AGAAATATCA CATAAGCATA TAATTCTTTG CTTTAATGCA AACAAAGTTG 60
CTTGAAAATG GCCTGGGTAA AATTCTTACG GAAACCTGGT GGCAATCTTG GAAAAGTGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0001508--P:action potential
GO:0051402--P:neuron apoptotic process
GO:0016579--P:protein deubiquitination
GO:0010996--P:response to auditory stimulus
GO:0007605--P:sensory perception of sound

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002136	Ailuropoda melanoleuca	88.04	0.00e+00	1893.00
IUUC-Apl-003843	Anas platyrhynchos	61.61	0.00e+00	1233.00
IUUC-Aca-004689	Anolis carolinensis	59.98	0.00e+00	1174.00
IUUC-Ame-010673	Astyanax mexicanus	72.16	0.00e+00	654.00
IUUC-Bta-012434	Bos taurus	85.52	0.00e+00	1809.00
IUUC-Cja-019625	Callithrix jacchus	84.69	0.00e+00	1782.00
IUUC-Cfa-020038	Canis familiaris	87.69	0.00e+00	1901.00
IUUC-Cpo-021503	Cavia porcellus	76.16	0.00e+00	1650.00
IUUC-Cre-022697	Chlamydomonas reinhardtii	24.23	3.00e-18	89.00
IUUC-Csa-024021	Chlorocebus sabaeus	84.14	0.00e+00	1774.00
IUUC-Cho-024769	Choloepus hoffmanni	76.27	0.00e+00	1606.00
IUUC-Dre-028438	Danio rerio	76.52	0.00e+00	634.00
IUUC-Dno-029317	Dasypus novemcinctus	81.85	0.00e+00	1700.00
IUUC-Dor-030249	Dipodomys ordii	95.23	0.00e+00	786.00
IUUC-Ete-032403	Echinops telfairi	78.11	0.00e+00	1669.00
IUUC-Eeu-035319	Erinaceus europaeus	63.39	2.00e-167	583.00
IUUC-Fca-036414	Felis catus	88.77	0.00e+00	1926.00
IUUC-Fal-036886	Ficedula albicollis	61.52	0.00e+00	1261.00
IUUC-Gmo-038617	Gadus morhua	74.24	3.00e-169	587.00
IUUC-Gga-040930	Gallus gallus	61.76	0.00e+00	1267.00
IUUC-Gac-041515	Gasterosteus aculeatus	77.39	5.00e-172	596.00
IUUC-Ggo-045573	Gorilla gorilla	84.97	0.00e+00	1815.00
IUUC-Hsa-046741	Homo sapiens	84.88	0.00e+00	1808.00
IUUC-Itr-048229	Ictidomys tridecemlineatus	65.24	0.00e+00	1281.00
IUUC-Lch-049932	Latimeria chalumnae	60.92	0.00e+00	881.00
IUUC-Loc-052180	Lepisosteus oculatus	60.60	0.00e+00	867.00
IUUC-Laf-054545	Loxodonta africana	82.60	0.00e+00	1830.00
IUUC-Mcc-054918	Macaca mulatta	84.04	0.00e+00	1788.00
IUUC-Meu-056802	Macropus eugenii	60.02	0.00e+00	1134.00
IUUC-Mga-059684	Meleagris gallopavo	60.07	0.00e+00	1180.00
IUUC-Mmr-060991	Microcebus murinus	81.22	0.00e+00	1441.00
IUUC-Mdo-062636	Monodelphis domestica	64.69	0.00e+00	1259.00
IUUC-Mmu-063910	Mus musculus	73.75	0.00e+00	1571.00
IUUC-Mac-064469	Musa acuminata	33.15	4.00e-19	90.90
IUUC-Mpu-065796	Mustela putorius furo	83.61	0.00e+00	1732.00
IUUC-Nle-069276	Nomascus leucogenys	84.42	0.00e+00	1710.00
IUUC-Opr-070545	Ochotona princeps	74.06	0.00e+00	868.00
IUUC-Ont-072449	Oreochromis niloticus	56.19	0.00e+00	718.00
IUUC-Oan-073493	Ornithorhynchus anatinus	59.57	0.00e+00	1014.00
IUUC-Ocu-074445	Oryctolagus cuniculus	78.92	0.00e+00	1720.00
IUUC-Oba-075174	Oryza barthii	30.54	1.00e-33	139.00
IUUC-Ogu-078705	Oryza glumaepatula	30.54	1.00e-33	139.00
IUUC-Olo-080872	Oryza longistaminata	30.54	6.00e-34	140.00
IUUC-Ome-081864	Oryza meridionalis	30.54	2.00e-33	139.00
IUUC-Oni-082109	Oryza nivara	30.54	1.00e-33	139.00
IUUC-Oru-084310	Oryza rufipogon	30.54	1.00e-33	139.00
IUUC-Osa-085583	Oryza sativa	31.56	2.00e-38	153.00
IUUC-Ola-087574	Oryzias latipes	70.60	9.00e-165	572.00
IUUC-Oga-087977	Otolemur garnettii	83.67	0.00e+00	1705.00
IUUC-Oar-089584	Ovis aries	85.24	0.00e+00	1786.00
IUUC-Ptr-091610	Pan troglodytes	84.69	0.00e+00	1781.00
IUUC-Pan-091828	Papio anubis	81.11	0.00e+00	1655.00
IUUC-Psi-093643	Pelodiscus sinensis	63.09	0.00e+00	1330.00
IUUC-Ppa-095930	Physcomitrella patens	30.98	8.00e-40	160.00
IUUC-Pfo-096829	Poecilia formosa	62.12	0.00e+00	635.00
IUUC-Pab-098190	Pongo abelii	84.88	0.00e+00	1775.00
IUUC-Pca-100356	Procavia capensis	71.49	0.00e+00	846.00
IUUC-Pva-102372	Pteropus vampyrus	79.43	0.00e+00	1667.00
IUUC-Rno-105609	Rattus norvegicus	64.72	0.00e+00	805.00
IUUC-Sha-107092	Sarcophilus harrisii	64.63	0.00e+00	1332.00
IUUC-Sar-113376	Sorex araneus	73.23	0.00e+00	867.00
IUUC-Ssc-115969	Sus scrofa	85.44	0.00e+00	1768.00
IUUC-Tgu-117134	Taeniopygia guttata	75.52	0.00e+00	1131.00
IUUC-Tru-117981	Takifugu rubripes	72.61	5.00e-168	583.00
IUUC-Tsy-119297	Tarsius syrichta	75.86	0.00e+00	1533.00
IUUC-Tni-120116	Tetraodon nigroviridis	76.65	4.00e-171	593.00
IUUC-Tbe-127607	Tupaia belangeri	79.68	0.00e+00	1660.00
IUUC-Ttr-128647	Tursiops truncatus	86.31	0.00e+00	1714.00
IUUC-Vpa-130288	Vicugna pacos	83.55	0.00e+00	1796.00
IUUC-Xtr-132277	Xenopus tropicalis	65.02	0.00e+00	957.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence