iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045376

UUCD1 version

UUC-GoG-01121

Ensembl Protein ID

ENSGGOP00000019390.1

UniProt Accession

G3RUB2; G3RUB2_GORGO

Protein Name

Uncharacterized protein

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000002044.2	ENSGGOT00000031571.1	ENSGGOP00000019390.1
ENSGGOG00000002044.2	ENSGGOT00000002057.2	ENSGGOP00000002014.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.80e-69	233.9	501	999

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 8    NtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgyeqqDaqEf 95
           +tC++  ++Q   ++ ++r+++l+ + + +n         +l+k+lq+lf+ l  ++k++a++pr +++a +   + f+  +qqD++E+
   Q: 501  ATCFFQGTIQICEMLLNFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAhTQKREAYAPRIFFEASR--PPWFTPRSQQDCSEY 578
           7***********************5555554.........7************9888999*********998..777************ PP
   S: 96   laflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
           l+flld+l+ee k    +++++ +e  e ++++l++         +  ++   +k+li+++F+g+l+++i+cl+c+++s++ e f+dls
   Q: 579  LRFLLDRLHEEEKIlkvQASHKPSEILECSETSLQEVaskaavltETPHTSDCEKTLIEKMFGGKLRTHIRCLNCRSTSQKVEAFTDLS 667
           ***********95577788888888888888888888888999977777888889********************************** PP
   S: 174  lpvpgkeetkke............................................................................. 185
           l++  +++ ++                                                                              
   Q: 668  LAFCPSSSLENMsvqdpasspsiqdgglmqasvpgpseepvvynpttaaficdslvnektigsppnefycsentsvpnesnkilvnkdv 756
           ***9999776669**************************************************************************** PP
   S: 186  ..........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspf 264
                     s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl L+l   
   Q: 757  pqkpggettpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVK 845
           *********************************************************************************99999954 PP
   S: 265  cts...............................peekqkekkkYeLiavvvHsG.slssGHYvayvkn.................... 301
            ++                               +e + ++ + Y L++vvvHsG s++sGHY++y++n                    
   Q: 846  RITsfsslseswsvdvdftdlsenlakklkpsgtDEASCTKLVPYLLSSVVVHSGiSSESGHYYSYARNitstdssyqmyhqsealala 934
           444366667777777777777777777777666644445559*********************************************** PP
   S: 302  ........................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                    +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 935  ssqshllgrespnavfeqdlenkeMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 999
           9999999999999999988865544555*******************999************986 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

GGGGRGPSRC CCGAPSSSPP RGSPAPSWGC RHPLLIPWPW PCSVATMDKI LEGLVSSSHP 60
LPLKRVIVRK VVESAEHWLD EAQCEAMFDL TTRLILEGQD PFQRQVGHQV LEAYARYHRP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGCGGTG GCCGTGGCCC GTCGCGCTGC TGCTGCGGCG CTCCAAGTTC ATCTCCGCCC 60
CGGGGCTCTC CTGCCCCATC TTGGGGCTGC CGCCACCCGC TCCTTATCCC TTGGCCCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	84.99	0.00e+00	1739.00
IUUC-Apl-003435	Anas platyrhynchos	71.34	0.00e+00	1172.00
IUUC-Aca-004556	Anolis carolinensis	67.04	0.00e+00	1216.00
IUUC-Ame-010616	Astyanax mexicanus	58.55	0.00e+00	1127.00
IUUC-Bta-013544	Bos taurus	87.95	0.00e+00	1693.00
IUUC-Cja-018745	Callithrix jacchus	89.96	0.00e+00	1802.00
IUUC-Cfa-020434	Canis familiaris	84.51	0.00e+00	1653.00
IUUC-Cpo-021666	Cavia porcellus	86.81	0.00e+00	1652.00
IUUC-Csa-023965	Chlorocebus sabaeus	93.12	0.00e+00	1905.00
IUUC-Cho-024809	Choloepus hoffmanni	78.31	0.00e+00	1159.00
IUUC-Cin-025604	Ciona intestinalis	37.34	3.00e-39	155.00
IUUC-Dre-028338	Danio rerio	59.76	0.00e+00	1152.00
IUUC-Dno-029372	Dasypus novemcinctus	87.09	0.00e+00	1726.00
IUUC-Dor-030752	Dipodomys ordii	83.25	0.00e+00	1123.00
IUUC-Ete-032588	Echinops telfairi	78.16	0.00e+00	879.00
IUUC-Eca-034416	Equus caballus	89.23	0.00e+00	1813.00
IUUC-Eeu-035132	Erinaceus europaeus	83.04	0.00e+00	854.00
IUUC-Fca-036137	Felis catus	88.53	0.00e+00	1764.00
IUUC-Fal-037297	Ficedula albicollis	71.32	0.00e+00	1355.00
IUUC-Gmo-038727	Gadus morhua	61.83	0.00e+00	915.00
IUUC-Gga-041091	Gallus gallus	69.74	0.00e+00	1276.00
IUUC-Gac-042082	Gasterosteus aculeatus	60.47	0.00e+00	1040.00
IUUC-Hsa-046444	Homo sapiens	94.74	0.00e+00	1897.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	88.44	0.00e+00	1822.00
IUUC-Lch-050500	Latimeria chalumnae	67.62	0.00e+00	1308.00
IUUC-Loc-052625	Lepisosteus oculatus	61.02	0.00e+00	1195.00
IUUC-Laf-053689	Loxodonta africana	88.47	0.00e+00	1759.00
IUUC-Mcc-055286	Macaca mulatta	93.21	0.00e+00	1867.00
IUUC-Meu-056437	Macropus eugenii	85.59	9.00e-174	604.00
IUUC-Mga-059905	Meleagris gallopavo	69.54	0.00e+00	1114.00
IUUC-Mmr-061397	Microcebus murinus	90.15	0.00e+00	1778.00
IUUC-Mdo-062833	Monodelphis domestica	81.32	0.00e+00	1667.00
IUUC-Mmu-063157	Mus musculus	85.56	0.00e+00	1697.00
IUUC-Mpu-066434	Mustela putorius furo	89.20	0.00e+00	1787.00
IUUC-Mlu-068178	Myotis lucifugus	87.24	0.00e+00	1699.00
IUUC-Nle-070153	Nomascus leucogenys	93.21	0.00e+00	1812.00
IUUC-Ont-072330	Oreochromis niloticus	59.83	0.00e+00	1142.00
IUUC-Oan-072709	Ornithorhynchus anatinus	74.57	0.00e+00	1165.00
IUUC-Ocu-074832	Oryctolagus cuniculus	89.29	0.00e+00	1766.00
IUUC-Ola-087003	Oryzias latipes	55.17	4.00e-48	183.00
IUUC-Oga-088517	Otolemur garnettii	86.00	0.00e+00	1734.00
IUUC-Oar-089472	Ovis aries	83.98	0.00e+00	1642.00
IUUC-Ptr-090996	Pan troglodytes	94.55	0.00e+00	1894.00
IUUC-Pan-091837	Papio anubis	91.80	0.00e+00	1873.00
IUUC-Psi-093236	Pelodiscus sinensis	71.09	0.00e+00	1045.00
IUUC-Pma-094349	Petromyzon marinus	50.05	0.00e+00	893.00
IUUC-Pfo-097193	Poecilia formosa	58.40	0.00e+00	1051.00
IUUC-Pab-098710	Pongo abelii	93.50	0.00e+00	1893.00
IUUC-Pca-100794	Procavia capensis	77.17	0.00e+00	1517.00
IUUC-Pva-102722	Pteropus vampyrus	88.06	0.00e+00	1766.00
IUUC-Rno-105743	Rattus norvegicus	85.09	0.00e+00	1664.00
IUUC-Sha-106563	Sarcophilus harrisii	79.47	0.00e+00	1327.00
IUUC-Sar-113533	Sorex araneus	72.87	0.00e+00	1433.00
IUUC-Ssc-116259	Sus scrofa	79.06	0.00e+00	1495.00
IUUC-Tgu-117475	Taeniopygia guttata	71.17	0.00e+00	1196.00
IUUC-Tru-118623	Takifugu rubripes	59.28	0.00e+00	1053.00
IUUC-Tsy-119250	Tarsius syrichta	87.48	0.00e+00	1374.00
IUUC-Tni-120441	Tetraodon nigroviridis	55.47	0.00e+00	973.00
IUUC-Tbe-127936	Tupaia belangeri	79.71	0.00e+00	869.00
IUUC-Ttr-128483	Tursiops truncatus	74.48	0.00e+00	822.00
IUUC-Vpa-130303	Vicugna pacos	88.66	0.00e+00	950.00
IUUC-Xtr-132773	Xenopus tropicalis	68.12	0.00e+00	1299.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence