iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072706

UUCD1 version

UUC-OrA-00760

Ensembl Protein ID

ENSOANP00000015578.2

UniProt Accession

F6RWK8; F6RWK8_ORNAN

Protein Name

Uncharacterized protein

Gene Name

UBE2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000009823.2	ENSOANT00000015581.2	ENSOANP00000015578.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.30e-52	176.2	11	142

Active Site

Position(s)	Description	Evidence
88	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 4    kelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekW 92
           k + +l++dpp g+s  p+++ ++++w+++i+Gpe+tp+e+g+Fkl ief+e+YP kPP+v+fl+k+fhPnvy++G++Cl+il+  ++W
   Q: 11   KRIPRLQEDPPVGVSGAPSEN-NIMQWNAVIFGPEGTPFEDGTFKLVIEFSEEYPNKPPTVRFLSKMFHPNVYADGSICLDILQ--NRW 96
           556789**************9.9************************************************************9..*** PP
   S: 93   spalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           sp+++v+s+l+siqsll+epnp+sp+n++aa+l+++n++ey+k+v+
   Q: 97   SPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVS 142
           *******************************************996 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

SLKPEHRDEM KRIPRLQEDP PVGVSGAPSE NNIMQWNAVI FGPEGTPFED GTFKLVIEFS 60
EEYPNKPPTV RFLSKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ SLLDEPNPNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGTTGAAAC CAGAGCACAG GGACGAGATG AAAAGGGAAG GTGGGACATA GGCACCTTGT 60
GGAGGCTCTG TCTGTCTGTC ACGTGACCTA TGCGGTGTCT TCTCTGTGGT GAGCCGAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005657--C:replication fork
GO:0001741--C:XY body
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0051026--P:chiasma assembly
GO:0033522--P:histone H2A ubiquitination
GO:0070076--P:histone lysine demethylation
GO:0006344--P:maintenance of chromatin silencing
GO:0045141--P:meiotic telomere clustering
GO:0043066--P:negative regulation of apoptotic process
GO:0043951--P:negative regulation of cAMP-mediated signaling
GO:0033128--P:negative regulation of histone phosphorylation
GO:0010845--P:positive regulation of reciprocal meiotic recombination
GO:0006301--P:postreplication repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0050821--P:protein stabilization
GO:0042493--P:response to drug
GO:0009411--P:response to UV
GO:0007288--P:sperm axoneme assembly
GO:0070193--P:synaptonemal complex organization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001001	Aegilops tauschii	69.18	7.00e-62	228.00
IUUC-Aml-002120	Ailuropoda melanoleuca	94.63	1.00e-80	291.00
IUUC-Atr-002862	Amborella trichopoda	70.75	1.00e-63	234.00
IUUC-Apl-004063	Anas platyrhynchos	92.62	2.00e-76	276.00
IUUC-Aca-005001	Anolis carolinensis	93.96	1.00e-80	290.00
IUUC-Aly-005584	Arabidopsis lyrata	70.55	1.00e-62	231.00
IUUC-Ath-007149	Arabidopsis thaliana	70.55	1.00e-62	231.00
IUUC-Ago-007745	Ashbya gossypii	63.70	2.00e-55	207.00
IUUC-Acl-008139	Aspergillus clavatus	63.70	5.00e-57	212.00
IUUC-Afl-008551	Aspergillus flavus	63.70	9.00e-57	211.00
IUUC-Afu-008980	Aspergillus fumigatus	63.70	9.00e-57	211.00
IUUC-Ani-009470	Aspergillus nidulans	47.69	5.00e-26	109.00
IUUC-Ang-009554	Aspergillus niger	63.70	9.00e-57	211.00
IUUC-Aor-010242	Aspergillus oryzae	63.70	9.00e-57	211.00
IUUC-Ate-010390	Aspergillus terreus	63.70	9.00e-57	211.00
IUUC-Ame-010743	Astyanax mexicanus	91.28	2.00e-77	280.00
IUUC-Bgr-012039	Blumeria graminis	66.91	5.00e-56	208.00
IUUC-Bta-012840	Bos taurus	94.63	1.00e-80	291.00
IUUC-Bci-013919	Botrytis cinerea	63.95	1.00e-57	214.00
IUUC-Bdi-014475	Brachypodium distachyon	69.86	2.00e-62	230.00
IUUC-Bol-015726	Brassica oleracea	70.55	3.00e-62	232.00
IUUC-Bra-018026	Brassica rapa	70.55	8.00e-63	231.00
IUUC-Cel-018244	Caenorhabditis elegans	80.14	8.00e-70	255.00
IUUC-Cja-019737	Callithrix jacchus	94.63	1.00e-80	291.00
IUUC-Cfa-020244	Canis familiaris	94.63	1.00e-80	291.00
IUUC-Cpo-022192	Cavia porcellus	94.63	1.00e-80	291.00
IUUC-Cre-022822	Chlamydomonas reinhardtii	69.84	8.00e-51	191.00
IUUC-Csa-023430	Chlorocebus sabaeus	94.63	1.00e-80	291.00
IUUC-Cho-024773	Choloepus hoffmanni	73.83	1.00e-57	214.00
IUUC-Cin-025537	Ciona intestinalis	75.17	2.00e-54	203.00
IUUC-Csv-025846	Ciona savignyi	76.19	2.00e-59	220.00
IUUC-Cgl-026381	Colletotrichum gloeosporioides	63.70	2.00e-57	213.00
IUUC-Cne-026864	Cryptococcus neoformans	65.73	1.00e-57	214.00
IUUC-Cme-027284	Cyanidioschyzon merolae	60.54	5.00e-47	180.00
IUUC-Dre-028774	Danio rerio	89.93	1.00e-77	280.00
IUUC-Dno-029661	Dasypus novemcinctus	94.63	1.00e-80	291.00
IUUC-Dor-030452	Dipodomys ordii	100.00	2.00e-78	283.00
IUUC-Dse-031487	Dothistroma septosporum	63.70	5.00e-57	212.00
IUUC-Dme-031863	Drosophila melanogaster	80.41	3.00e-69	253.00
IUUC-Ete-032595	Echinops telfairi	91.28	7.00e-78	281.00
IUUC-Eca-033377	Equus caballus	94.63	1.00e-80	291.00
IUUC-Eeu-035191	Erinaceus europaeus	70.86	2.00e-54	203.00
IUUC-Fca-036336	Felis catus	94.63	1.00e-80	291.00
IUUC-Fal-037474	Ficedula albicollis	94.96	5.00e-65	238.00
IUUC-Fox-037808	Fusarium oxysporum	63.70	3.00e-57	213.00
IUUC-Fso-038232	Fusarium solani	63.70	3.00e-57	213.00
IUUC-Gmo-038517	Gadus morhua	89.93	3.00e-77	279.00
IUUC-Ggr-039875	Gaeumannomyces graminis	63.89	2.00e-56	210.00
IUUC-Gga-040494	Gallus gallus	94.63	1.00e-80	291.00
IUUC-Gac-042471	Gasterosteus aculeatus	89.93	4.00e-78	282.00
IUUC-Gma-043865	Glycine max	70.55	2.00e-63	233.00
IUUC-Ggo-044580	Gorilla gorilla	97.89	3.00e-79	286.00
IUUC-Hsa-046239	Homo sapiens	94.63	1.00e-80	291.00
IUUC-Hvu-047054	Hordeum vulgare	69.18	7.00e-62	228.00
IUUC-Itr-048960	Ictidomys tridecemlineatus	94.63	1.00e-80	291.00
IUUC-Kpa-049225	Komagataella pastoris	63.27	2.00e-55	207.00
IUUC-Lch-050283	Latimeria chalumnae	91.89	2.00e-78	283.00
IUUC-Lpe-051301	Leersia perrieri	70.55	7.00e-63	231.00
IUUC-Loc-051962	Lepisosteus oculatus	92.62	4.00e-79	285.00
IUUC-Lma-053214	Leptosphaeria maculans	43.61	3.00e-31	126.00
IUUC-Laf-053380	Loxodonta africana	94.63	1.00e-80	291.00
IUUC-Mcc-054819	Macaca mulatta	94.63	6.00e-81	292.00
IUUC-Meu-056103	Macropus eugenii	100.00	2.00e-78	283.00
IUUC-Mor-057087	Magnaporthe oryzae	67.16	1.00e-54	204.00
IUUC-Mpo-057498	Magnaporthe poae	64.34	2.00e-56	211.00
IUUC-Mtr-058305	Medicago truncatula	70.55	4.00e-63	232.00
IUUC-Mla-058876	Melampsora laricipopulina	68.49	5.00e-52	196.00
IUUC-Mga-059863	Meleagris gallopavo	99.29	2.00e-79	286.00
IUUC-Mvi-060330	Microbotryum violaceum	66.89	3.00e-51	193.00
IUUC-Mmr-060630	Microcebus murinus	94.63	1.00e-80	291.00
IUUC-Mdo-062676	Monodelphis domestica	94.63	1.00e-80	291.00
IUUC-Mmu-063491	Mus musculus	94.63	1.00e-80	291.00
IUUC-Mac-064774	Musa acuminata	70.55	8.00e-63	231.00
IUUC-Mpu-065803	Mustela putorius furo	94.63	1.00e-80	291.00
IUUC-Mlu-067147	Myotis lucifugus	94.63	1.00e-80	291.00
IUUC-Nfi-068580	Neosartorya fischeri	63.70	9.00e-57	211.00
IUUC-Ncr-068913	Neurospora crassa	64.14	2.00e-57	213.00
IUUC-Nle-070105	Nomascus leucogenys	94.63	1.00e-80	291.00
IUUC-Opr-070935	Ochotona princeps	94.63	1.00e-80	291.00
IUUC-Ont-071335	Oreochromis niloticus	89.93	6.00e-78	281.00
IUUC-Ocu-074130	Oryctolagus cuniculus	94.63	1.00e-80	291.00
IUUC-Oba-075896	Oryza barthii	69.86	3.00e-62	229.00
IUUC-Obr-076713	Oryza brachyantha	70.55	7.00e-63	231.00
IUUC-Ogl-077116	Oryza glaberrima	70.55	7.00e-63	231.00
IUUC-Ogu-078696	Oryza glumaepatula	70.55	7.00e-63	231.00
IUUC-Oin-079099	Oryza indica	70.55	7.00e-63	231.00
IUUC-Olo-081018	Oryza longistaminata	59.26	2.00e-53	200.00
IUUC-Ome-081285	Oryza meridionalis	70.55	7.00e-63	231.00
IUUC-Oni-082088	Oryza nivara	70.55	7.00e-63	231.00
IUUC-Opu-083310	Oryza punctata	70.55	7.00e-63	231.00
IUUC-Oru-084449	Oryza rufipogon	70.55	7.00e-63	231.00
IUUC-Osa-085923	Oryza sativa	70.55	7.00e-63	231.00
IUUC-Ola-087160	Oryzias latipes	89.93	6.00e-78	281.00
IUUC-Olu-087830	Ostreococcus lucimarinus	72.60	2.00e-54	203.00
IUUC-Oga-088836	Otolemur garnettii	94.63	1.00e-80	291.00
IUUC-Oar-090141	Ovis aries	94.63	1.00e-80	291.00
IUUC-Ptr-091453	Pan troglodytes	94.63	1.00e-80	291.00
IUUC-Pan-092511	Papio anubis	94.63	1.00e-80	291.00
IUUC-Psi-093968	Pelodiscus sinensis	93.96	1.00e-80	290.00
IUUC-Pma-094376	Petromyzon marinus	87.25	8.00e-76	275.00
IUUC-Pno-094935	Phaeosphaeria nodorum	63.70	2.00e-57	213.00
IUUC-Ppa-095689	Physcomitrella patens	71.23	5.00e-54	202.00
IUUC-Pfo-096656	Poecilia formosa	89.26	4.00e-77	279.00
IUUC-Pab-098121	Pongo abelii	94.63	1.00e-80	291.00
IUUC-Pop-099517	Populus trichocarpa	70.55	5.00e-63	232.00
IUUC-Pca-100906	Procavia capensis	83.22	2.00e-69	253.00
IUUC-Ppe-101594	Prunus persica	70.55	8.00e-63	231.00
IUUC-Pva-102380	Pteropus vampyrus	88.59	2.00e-74	270.00
IUUC-Pgr-103611	Puccinia graminis	67.81	3.00e-52	196.00
IUUC-Ptt-103971	Puccinia triticina	72.88	1.00e-44	170.00
IUUC-Pte-104378	Pyrenophora teres	64.38	1.00e-57	214.00
IUUC-Pyt-104757	Pyrenophora triticirepentis	64.38	1.00e-57	214.00
IUUC-Rno-105772	Rattus norvegicus	94.63	5.00e-81	292.00
IUUC-Sce-106283	Saccharomyces cerevisiae	63.70	2.00e-55	207.00
IUUC-Sha-107650	Sarcophilus harrisii	93.29	6.00e-79	285.00
IUUC-Sja-107790	Schizosaccharomyces japonicus	66.67	1.00e-51	194.00
IUUC-Spo-108073	Schizosaccharomyces pombe	66.67	9.00e-52	194.00
IUUC-Ssl-108432	Sclerotinia sclerotiorum	63.95	1.00e-57	214.00
IUUC-Smo-109036	Selaginella moellendorffii	71.23	3.00e-63	233.00
IUUC-Sit-110731	Setaria italica	70.55	7.00e-63	231.00
IUUC-Sly-111506	Solanum lycopersicum	71.23	3.00e-63	233.00
IUUC-Stu-112080	Solanum tuberosum	71.23	3.00e-63	233.00
IUUC-Sar-113429	Sorex araneus	94.63	1.00e-80	291.00
IUUC-Sbi-114289	Sorghum bicolor	70.55	7.00e-63	231.00
IUUC-Sre-115106	Sporisorium reilianum	69.59	1.00e-53	201.00
IUUC-Ssc-115257	Sus scrofa	92.62	1.00e-78	283.00
IUUC-Tgu-116604	Taeniopygia guttata	88.68	2.00e-78	283.00
IUUC-Tru-118576	Takifugu rubripes	89.26	2.00e-76	276.00
IUUC-Tsy-119000	Tarsius syrichta	94.63	1.00e-80	291.00
IUUC-Tni-119745	Tetraodon nigroviridis	89.26	9.00e-77	277.00
IUUC-Tca-121827	Theobroma cacao	70.55	4.00e-63	232.00
IUUC-Tre-122002	Trichoderma reesei	63.70	4.00e-57	212.00
IUUC-Tvi-122331	Trichoderma virens	63.70	4.00e-57	212.00
IUUC-Tae-125807	Triticum aestivum	69.86	2.00e-62	230.00
IUUC-Tur-126866	Triticum urartu	69.86	2.00e-62	230.00
IUUC-Tme-127148	Tuber melanosporum	65.97	1.00e-57	214.00
IUUC-Tbe-127921	Tupaia belangeri	92.62	2.00e-76	276.00
IUUC-Ttr-129121	Tursiops truncatus	94.63	1.00e-80	291.00
IUUC-Uma-129561	Ustilago maydis	69.59	7.00e-54	202.00
IUUC-Vda-129711	Verticillium dahliae	63.70	2.00e-57	213.00
IUUC-Vpa-130570	Vicugna pacos	93.43	2.00e-71	259.00
IUUC-Vvi-131108	Vitis vinifera	71.92	1.00e-63	234.00
IUUC-Xtr-131824	Xenopus tropicalis	93.29	1.00e-79	287.00
IUUC-Xma-133667	Xiphophorus maculatus	89.93	6.00e-78	281.00
IUUC-Yli-134660	Yarrowia lipolytica	60.96	4.00e-56	209.00
IUUC-Zma-135584	Zea mays	69.18	8.00e-62	228.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence