iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-012848

Ensembl Protein ID

ENSBTAP00000020493.5

UniProt Accession

F1MJ96; F1MJ96_BOVIN

Genbank Protein ID

ENSBTAP00000020493

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02020614

Gene Name

ARHGEF37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000015419.5	ENSBTAT00000020493.5	ENSBTAP00000020493.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.70e-11	41.8	605	662

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v ++y+++a ++ e +l++G  v+v+  ++++ + +W     e +g+rG +P+ F +++
   Q: 605  QVVAMYPFMARSSHEVSLQAGQRVTVLeaQDKKGNPEWSLV--EVNGQRGYVPSSFLARA 662
           799************************9889999****977..9************9886 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MTNHGDDALS SRTGAPDGDD RLSEDRSLLQ QRLAVRELID TEVSYLHVLQ LCASDIRSRL 60
QQLPQGDLDV LFSNIDDIIK VNSRLLHDLQ ETASREEEQV QLIGNAFLEF QEELEQVYKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCGCTGCGC GGGTCCGGGA GTCCTGCGCC TTTCCCACCC TGGCTGCGCA GTCCCCAGGG 60
CAGCCGAGCT CCCCGTGGGA GCTGGCACCT TGCGAGCGCG GTGAGTCCAC TCGGGCGATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS50010--DH_2
PS50002--SH3

Pfam

PF03114--BAR
PF00621--RhoGEF
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043547--P:positive regulation of GTPase activity
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011907	Astyanax mexicanus	37.83	4.00e-123	435.00
IUUC-Cfa-021281	Canis familiaris	87.85	0.00e+00	1128.00
IUUC-Csa-023043	Chlorocebus sabaeus	85.48	0.00e+00	1117.00
IUUC-Dre-028496	Danio rerio	38.83	2.00e-122	432.00
IUUC-Ggo-044900	Gorilla gorilla	86.22	0.00e+00	1129.00
IUUC-Hsa-045684	Homo sapiens	85.93	0.00e+00	1156.00
IUUC-Lch-050096	Latimeria chalumnae	46.59	5.00e-162	564.00
IUUC-Loc-051937	Lepisosteus oculatus	42.31	4.00e-132	465.00
IUUC-Mcc-054950	Macaca mulatta	85.48	0.00e+00	1121.00
IUUC-Meu-056383	Macropus eugenii	69.82	2.00e-172	599.00
IUUC-Mdo-062021	Monodelphis domestica	69.71	0.00e+00	889.00
IUUC-Mmu-064186	Mus musculus	77.96	0.00e+00	1001.00
IUUC-Ptr-090508	Pan troglodytes	86.07	0.00e+00	1126.00
IUUC-Pan-092517	Papio anubis	85.19	0.00e+00	1095.00
IUUC-Pfo-096703	Poecilia formosa	38.77	3.00e-121	429.00
IUUC-Pab-098542	Pongo abelii	85.63	0.00e+00	1117.00
IUUC-Rno-105455	Rattus norvegicus	80.37	0.00e+00	1014.00
IUUC-Sha-106562	Sarcophilus harrisii	68.01	0.00e+00	866.00
IUUC-Ttr-128242	Tursiops truncatus	88.00	0.00e+00	1144.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence