iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106562

Ensembl Protein ID

ENSSHAP00000018335.1

UniProt Accession

G3WSD0; G3WSD0_SARHA

Genbank Protein ID

ENSSHAP00000018335

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01016688

Gene Name

ARHGEF37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000015563.1	ENSSHAT00000018485.1	ENSSHAP00000018335.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.00e-11	41.9	609	666

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v + y++ a ++ e +l++G  v+v+  ++++ + +W     e +g+rG +P+nF + +
   Q: 609  QVVAAYPFAARSSHEVSLQAGQPVTVLerQDKKGNPEWSLV--EVNGQRGYVPSNFLVPV 666
           78999**********************88889999***977..9************9877 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MAGYQEGESP SPGENSGDES QGDEAIKILE KMKLNQRLAA KELISTEARY VHNLQLCASD 60
IRSQLHELPE EDLDVIFSNI NDVIKVNSRF LKGLEEAESE EEQLSLLGNL FLEFQEEMES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGGAACTGA GGCTGTTCCT GCGCATGCAC GTTACGGTGA AGGCAGGTCC GGTCCCGCCC 60
GTTCGCTTGG TTCTGGCTGC TCCGTGGGCT GGCAATGGAG AAAGAACCGG TTGCTTATTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS50010--DH_2
PS50002--SH3

Pfam

PF00621--RhoGEF
PF07653--SH3_2
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

KEGG

shr:100915641

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011907	Astyanax mexicanus	41.58	5.00e-136	478.00
IUUC-Bta-012848	Bos taurus	68.30	0.00e+00	873.00
IUUC-Cfa-021281	Canis familiaris	69.76	0.00e+00	884.00
IUUC-Csa-023043	Chlorocebus sabaeus	70.59	0.00e+00	875.00
IUUC-Dre-028496	Danio rerio	41.55	1.00e-135	476.00
IUUC-Ggo-044900	Gorilla gorilla	69.81	0.00e+00	884.00
IUUC-Hsa-045684	Homo sapiens	69.66	0.00e+00	892.00
IUUC-Lch-050096	Latimeria chalumnae	46.89	4.00e-167	581.00
IUUC-Loc-051937	Lepisosteus oculatus	42.71	3.00e-138	485.00
IUUC-Mcc-054950	Macaca mulatta	69.97	0.00e+00	870.00
IUUC-Meu-056383	Macropus eugenii	88.96	0.00e+00	780.00
IUUC-Mdo-062021	Monodelphis domestica	87.03	0.00e+00	1160.00
IUUC-Mmu-064186	Mus musculus	63.53	0.00e+00	837.00
IUUC-Ptr-090508	Pan troglodytes	69.97	0.00e+00	888.00
IUUC-Pan-092517	Papio anubis	70.59	0.00e+00	868.00
IUUC-Pfo-096703	Poecilia formosa	40.84	4.00e-129	455.00
IUUC-Pab-098542	Pongo abelii	69.97	0.00e+00	886.00
IUUC-Rno-105455	Rattus norvegicus	66.21	0.00e+00	868.00
IUUC-Ttr-128242	Tursiops truncatus	68.77	0.00e+00	853.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence