iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053338

UUCD1 version

UUC-LoA-00332

Ensembl Protein ID

ENSLAFP00000008262.3

UniProt Accession

G3T4H7; G3T4H7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000009857.3	ENSLAFT00000009861.3	ENSLAFP00000008262.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-43	145.8	637	669
UBD/Beta-Prp	2.90e-66	224.0	56	265

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gHt+++t+la+   +d++lvs+s+Dgt +vWD+
   Q: 637  GHTAKITSLAWsphHDGRLVSASYDGTAQVWDT 669
           8***********8766****************7 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqc 128
           ++ +l gh++ v+  +fs++     + +t+s+D+t+k+wd++t + v     h++++ +l++sp  +d +vsG++  +i ++ l+ +  
   Q: 56   VIGELVGHTERVSGFTFSHHPGqynLCATSSDDGTVKIWDVETKTVVTEHALHQHTISALHWSPrVKDLIVSGDEKGVIFCYWLNRNDS 144
           57899**************965677***************************************666**************97777777 PP
   S: 129  leetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls...........fdsng............ 192
            + +++ + +++ c++ +p   +l++ G +D++v + d+ k g+++++l+g h+d ++s++           +                
   Q: 145  QH-LFT-EPRTIFCLTCSPHHeDLVAIGYKDGMVVIIDIsKKGEVIHRLRG-HDDEIHSIAwcplpgedclsI---Nqeenseepeipn 227
           76.555.555566666666555*****************999********9.*********777666666541...0456778899999 PP
   S: 193  ............kelvsgsldgtvklwdlqtgecvrtl 218
                        +l++gs+d+t+++w++++g+ v++l
   Q: 228  gkvipqtpvtkgCYLATGSKDQTIRIWSCSRGRGVMIL 265
           999999999999******************99877765 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MGQEPRTLPP SPNWYCARCS DAVPGGLFGF AARTSVFLVR VGPGAGASHG TPPFRVIGEL 60
VGHTERVSGF TFSHHPGQYN LCATSSDDGT VKIWDVETKT VVTEHALHQH TISALHWSPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCAAG AACCGCGGAC GCTGCCTCCG TCCCCCAACT GGTACTGCGC CCGCTGCAGC 60
GACGCCGTAC CCGGGGGTCT TTTCGGCTTC GCGGCGCGGA CCTCGGTCTT CCTAGTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	87.45	0.00e+00	2594.00
IUUC-Apl-003586	Anas platyrhynchos	63.30	0.00e+00	1658.00
IUUC-Aca-004956	Anolis carolinensis	62.67	0.00e+00	1875.00
IUUC-Ame-010753	Astyanax mexicanus	50.63	0.00e+00	1493.00
IUUC-Bta-012315	Bos taurus	86.94	0.00e+00	2602.00
IUUC-Cja-019334	Callithrix jacchus	86.72	0.00e+00	2648.00
IUUC-Cfa-021254	Canis familiaris	86.90	0.00e+00	2650.00
IUUC-Cpo-021984	Cavia porcellus	81.06	0.00e+00	2326.00
IUUC-Csa-023650	Chlorocebus sabaeus	87.34	0.00e+00	2626.00
IUUC-Cho-024860	Choloepus hoffmanni	83.25	0.00e+00	2419.00
IUUC-Cin-025778	Ciona intestinalis	38.03	0.00e+00	673.00
IUUC-Csv-026313	Ciona savignyi	41.40	1.00e-166	580.00
IUUC-Dre-028096	Danio rerio	63.17	0.00e+00	1018.00
IUUC-Dno-029799	Dasypus novemcinctus	89.74	0.00e+00	2263.00
IUUC-Dor-030885	Dipodomys ordii	75.26	0.00e+00	1103.00
IUUC-Ete-032918	Echinops telfairi	84.11	0.00e+00	2524.00
IUUC-Eca-034144	Equus caballus	86.87	0.00e+00	2545.00
IUUC-Eeu-034843	Erinaceus europaeus	77.66	0.00e+00	1768.00
IUUC-Fca-035948	Felis catus	86.93	0.00e+00	2588.00
IUUC-Fal-037303	Ficedula albicollis	62.22	0.00e+00	1813.00
IUUC-Gmo-039591	Gadus morhua	43.51	0.00e+00	932.00
IUUC-Gga-040570	Gallus gallus	63.02	0.00e+00	1659.00
IUUC-Gac-042646	Gasterosteus aculeatus	48.25	0.00e+00	1367.00
IUUC-Ggo-045605	Gorilla gorilla	80.60	0.00e+00	1842.00
IUUC-Hsa-046122	Homo sapiens	88.12	0.00e+00	2620.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	89.26	0.00e+00	2295.00
IUUC-Lch-050489	Latimeria chalumnae	51.62	0.00e+00	893.00
IUUC-Loc-052259	Lepisosteus oculatus	60.94	0.00e+00	980.00
IUUC-Mcc-055442	Macaca mulatta	87.53	0.00e+00	2628.00
IUUC-Meu-056245	Macropus eugenii	82.14	0.00e+00	870.00
IUUC-Mga-060202	Meleagris gallopavo	63.25	0.00e+00	1716.00
IUUC-Mmr-061730	Microcebus murinus	86.91	0.00e+00	2584.00
IUUC-Mdo-062880	Monodelphis domestica	74.25	0.00e+00	2229.00
IUUC-Mmu-063930	Mus musculus	80.98	0.00e+00	2329.00
IUUC-Mpu-066605	Mustela putorius furo	86.73	0.00e+00	2607.00
IUUC-Mlu-067765	Myotis lucifugus	87.15	0.00e+00	2649.00
IUUC-Nle-069183	Nomascus leucogenys	87.36	0.00e+00	2586.00
IUUC-Opr-070659	Ochotona princeps	75.78	0.00e+00	1147.00
IUUC-Ont-072356	Oreochromis niloticus	61.76	0.00e+00	1011.00
IUUC-Oan-073056	Ornithorhynchus anatinus	71.48	0.00e+00	1994.00
IUUC-Ocu-073881	Oryctolagus cuniculus	86.34	0.00e+00	2624.00
IUUC-Ola-087120	Oryzias latipes	57.49	1.00e-67	249.00
IUUC-Olu-087648	Ostreococcus lucimarinus	25.29	9.00e-31	129.00
IUUC-Oga-088343	Otolemur garnettii	87.87	0.00e+00	2623.00
IUUC-Oar-089257	Ovis aries	87.67	0.00e+00	2645.00
IUUC-Ptr-090497	Pan troglodytes	87.99	0.00e+00	2592.00
IUUC-Pan-092638	Papio anubis	87.34	0.00e+00	2626.00
IUUC-Psi-093096	Pelodiscus sinensis	65.13	0.00e+00	1645.00
IUUC-Pma-094571	Petromyzon marinus	43.04	1.00e-82	300.00
IUUC-Pfo-096742	Poecilia formosa	49.07	0.00e+00	1395.00
IUUC-Pab-098153	Pongo abelii	87.72	0.00e+00	2649.00
IUUC-Pca-100957	Procavia capensis	85.10	0.00e+00	2536.00
IUUC-Pva-102439	Pteropus vampyrus	88.57	0.00e+00	2661.00
IUUC-Rno-105891	Rattus norvegicus	80.83	0.00e+00	2301.00
IUUC-Sha-107181	Sarcophilus harrisii	74.31	0.00e+00	2110.00
IUUC-Ssc-115413	Sus scrofa	86.93	0.00e+00	2644.00
IUUC-Tgu-117082	Taeniopygia guttata	62.99	0.00e+00	1790.00
IUUC-Tru-118491	Takifugu rubripes	59.80	0.00e+00	956.00
IUUC-Tsy-119629	Tarsius syrichta	93.77	5.00e-168	585.00
IUUC-Tni-120240	Tetraodon nigroviridis	60.27	0.00e+00	963.00
IUUC-Tbe-127673	Tupaia belangeri	77.18	0.00e+00	2150.00
IUUC-Ttr-128562	Tursiops truncatus	84.47	0.00e+00	2538.00
IUUC-Vpa-130596	Vicugna pacos	84.87	0.00e+00	1872.00
IUUC-Xtr-132469	Xenopus tropicalis	56.31	0.00e+00	1653.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence