iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033349

UUCD1 version

UUC-EqC-00490

Ensembl Protein ID

ENSECAP00000021554.1

UniProt Accession

F6Y1D9; F6Y1D9_HORSE

Protein Name

Uncharacterized protein

Gene Name

RNF145

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000024020.1	ENSECAT00000025887.1	ENSECAP00000021554.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.00e-10	39.1	537	574

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC++d+k   +++pC H+fha Cl+kw       + + +CPlC
   Q: 537  CAICYQDMKS-AVITPCSHFFHAGCLKKW------LYVQETCPLC 574
           ********99.888***************......********** PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAAKEKLEAV LNVALRVPSI MLLDVLYRWD VSSFFQQIQR SSLSNNPLFQ YKYLALNMHY 60
VGYILSVVLL TLPRQHLVQL YLYFLTALLL YAGHQISRDY VRSELESAYE GPMYLEPLSM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAAGAAAAA ACATGGCTGC AAAGGAGAAA CTGGAGGCTG TGTTAAATGT GGCCCTGAGG 60
GTGCCAAGCA TCATGCTGTT GGATGTCCTG TACAGATGGG ATGTCAGCTC CTTCTTCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ecb:106781589

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002354	Ailuropoda melanoleuca	98.07	0.00e+00	1151.00
IUUC-Apl-003823	Anas platyrhynchos	94.22	0.00e+00	1108.00
IUUC-Aca-004944	Anolis carolinensis	95.00	0.00e+00	1108.00
IUUC-Ame-011578	Astyanax mexicanus	88.97	0.00e+00	1010.00
IUUC-Bta-012560	Bos taurus	97.42	0.00e+00	1135.00
IUUC-Cel-018539	Caenorhabditis elegans	28.33	8.00e-63	234.00
IUUC-Cja-018929	Callithrix jacchus	96.15	0.00e+00	1127.00
IUUC-Cfa-021110	Canis familiaris	97.75	0.00e+00	1150.00
IUUC-Cpo-022452	Cavia porcellus	97.43	0.00e+00	1140.00
IUUC-Csa-024116	Chlorocebus sabaeus	97.27	0.00e+00	1143.00
IUUC-Csv-025845	Ciona savignyi	40.62	3.00e-32	130.00
IUUC-Dre-028299	Danio rerio	88.79	0.00e+00	1042.00
IUUC-Dno-029615	Dasypus novemcinctus	97.75	0.00e+00	1155.00
IUUC-Ete-032551	Echinops telfairi	74.25	0.00e+00	827.00
IUUC-Eeu-035349	Erinaceus europaeus	98.04	0.00e+00	712.00
IUUC-Fca-035696	Felis catus	97.91	0.00e+00	1152.00
IUUC-Fal-037495	Ficedula albicollis	93.78	0.00e+00	1097.00
IUUC-Gmo-039374	Gadus morhua	86.83	0.00e+00	1009.00
IUUC-Gga-040146	Gallus gallus	94.67	0.00e+00	1108.00
IUUC-Gac-041731	Gasterosteus aculeatus	83.84	0.00e+00	1027.00
IUUC-Ggo-045158	Gorilla gorilla	97.08	0.00e+00	1129.00
IUUC-Hsa-045787	Homo sapiens	97.27	0.00e+00	1142.00
IUUC-Itr-048928	Ictidomys tridecemlineatus	97.17	0.00e+00	1033.00
IUUC-Lch-050499	Latimeria chalumnae	94.31	0.00e+00	1051.00
IUUC-Loc-052482	Lepisosteus oculatus	90.88	0.00e+00	1045.00
IUUC-Laf-053362	Loxodonta africana	98.23	0.00e+00	1158.00
IUUC-Mcc-055779	Macaca mulatta	97.24	0.00e+00	1130.00
IUUC-Meu-056130	Macropus eugenii	77.56	4.00e-143	501.00
IUUC-Mga-059742	Meleagris gallopavo	93.90	0.00e+00	1104.00
IUUC-Mmr-060812	Microcebus murinus	97.75	0.00e+00	1150.00
IUUC-Mdo-063045	Monodelphis domestica	96.33	0.00e+00	1109.00
IUUC-Mmu-064377	Mus musculus	97.43	0.00e+00	1155.00
IUUC-Mpu-066637	Mustela putorius furo	97.75	0.00e+00	1148.00
IUUC-Mlu-066985	Myotis lucifugus	97.43	0.00e+00	1152.00
IUUC-Nle-069833	Nomascus leucogenys	97.24	0.00e+00	1132.00
IUUC-Opr-070210	Ochotona princeps	90.61	8.00e-124	437.00
IUUC-Ont-072116	Oreochromis niloticus	86.13	0.00e+00	1043.00
IUUC-Oan-073730	Ornithorhynchus anatinus	95.96	0.00e+00	1118.00
IUUC-Ocu-074958	Oryctolagus cuniculus	97.58	0.00e+00	1146.00
IUUC-Ola-087368	Oryzias latipes	89.14	0.00e+00	1023.00
IUUC-Oga-088301	Otolemur garnettii	97.23	0.00e+00	1129.00
IUUC-Oar-089745	Ovis aries	97.27	0.00e+00	1145.00
IUUC-Ptr-091397	Pan troglodytes	97.11	0.00e+00	1140.00
IUUC-Pan-092817	Papio anubis	97.27	0.00e+00	1143.00
IUUC-Psi-093820	Pelodiscus sinensis	92.57	0.00e+00	1071.00
IUUC-Pma-094457	Petromyzon marinus	66.87	3.00e-172	597.00
IUUC-Pfo-097173	Poecilia formosa	84.21	0.00e+00	1039.00
IUUC-Pab-097630	Pongo abelii	97.27	0.00e+00	1143.00
IUUC-Pca-100472	Procavia capensis	95.02	0.00e+00	1125.00
IUUC-Pva-102485	Pteropus vampyrus	96.58	0.00e+00	1080.00
IUUC-Rno-106029	Rattus norvegicus	99.34	0.00e+00	1136.00
IUUC-Sha-106580	Sarcophilus harrisii	97.10	0.00e+00	1146.00
IUUC-Ssc-116438	Sus scrofa	95.97	0.00e+00	1026.00
IUUC-Tgu-116638	Taeniopygia guttata	94.06	0.00e+00	1089.00
IUUC-Tru-117779	Takifugu rubripes	86.45	0.00e+00	1041.00
IUUC-Tsy-119541	Tarsius syrichta	95.26	0.00e+00	1081.00
IUUC-Tni-119862	Tetraodon nigroviridis	87.60	0.00e+00	1038.00
IUUC-Tbe-127328	Tupaia belangeri	90.88	0.00e+00	998.00
IUUC-Ttr-129066	Tursiops truncatus	95.60	2.00e-180	625.00
IUUC-Xtr-132826	Xenopus tropicalis	90.65	0.00e+00	1089.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence