iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020776

Ensembl Protein ID

ENSCAFP00000004572.2

UniProt Accession

E2R9L3; E2R9L3_CANLF

Genbank Protein ID

ENSCAFP00000004572

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03009404

Gene Name

NOD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000003074.2	ENSCAFT00000004933.2	ENSCAFP00000004572.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/CARD	83.84	0.00e+00	1474.00	IUUC-Hsa-046886

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

MWAKQSLVPL AMEKQSHGEM GIIPSESHSH IKLLKINREL LVTHIRNTQC LVDNLLENDY 60
FSSEDAEIVG ACPTQPDKVR KILDLVQSKG EEASEFLLYV LQQLEDAYVD LRPWLSEIGF 120

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Nucleotide Sequence
(Fasta)

GGGGGGGGTT TCGGCGCTCC CGGGTCTCAG CGCTGGCGAG GGAGGGGGGT TGTCTCCGCG 60
CTAGAGGATC TCGGCCCTTG GGGGGCGGTA TCCGCGCTCC CAGGGTCTCC GCGCTCCCGG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR007109--Brix
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR007111--NACHT_NTPase

PROSITE

PS50209--CARD
PS50837--NACHT

Pfam

PF00619--CARD
PF13516--LRR_6

Gene Ontology

GO:0016323--C:basolateral plasma membrane
GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0071225--P:cellular response to muramyl dipeptide
GO:0050830--P:defense response to Gram-positive bacterium
GO:0016045--P:detection of bacterium
GO:0042228--P:interleukin-8 biosynthetic process
GO:0035556--P:intracellular signal transduction
GO:0002606--P:positive regulation of dendritic cell antigen processing and presentation
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032755--P:positive regulation of interleukin-6 production
GO:0046330--P:positive regulation of JNK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0032760--P:positive regulation of tumor necrosis factor production
GO:1904417--P:positive regulation of xenophagy

KEGG

cfa:482382

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001299	Ailuropoda melanoleuca	89.19	0.00e+00	1511.00
IUUC-Apl-003908	Anas platyrhynchos	63.89	0.00e+00	1171.00
IUUC-Aca-005144	Anolis carolinensis	60.92	0.00e+00	1146.00
IUUC-Ame-010829	Astyanax mexicanus	51.75	0.00e+00	912.00
IUUC-Bta-013358	Bos taurus	83.96	0.00e+00	1505.00
IUUC-Cja-019392	Callithrix jacchus	82.48	0.00e+00	1480.00
IUUC-Cpo-021393	Cavia porcellus	78.41	0.00e+00	1427.00
IUUC-Csa-023872	Chlorocebus sabaeus	83.42	0.00e+00	1534.00
IUUC-Cho-024569	Choloepus hoffmanni	70.35	1.00e-169	590.00
IUUC-Dre-027478	Danio rerio	51.42	0.00e+00	876.00
IUUC-Dno-029231	Dasypus novemcinctus	83.21	0.00e+00	1520.00
IUUC-Dor-030251	Dipodomys ordii	57.32	1.00e-157	550.00
IUUC-Ete-032484	Echinops telfairi	73.66	0.00e+00	768.00
IUUC-Eca-033564	Equus caballus	87.38	0.00e+00	1583.00
IUUC-Eeu-034456	Erinaceus europaeus	66.75	3.00e-138	485.00
IUUC-Fca-036372	Felis catus	87.93	0.00e+00	1557.00
IUUC-Fal-037418	Ficedula albicollis	63.29	0.00e+00	1173.00
IUUC-Gmo-038740	Gadus morhua	51.13	0.00e+00	908.00
IUUC-Gga-040775	Gallus gallus	63.39	0.00e+00	1204.00
IUUC-Gac-041612	Gasterosteus aculeatus	50.21	0.00e+00	899.00
IUUC-Ggo-045161	Gorilla gorilla	82.76	0.00e+00	1276.00
IUUC-Hsa-046886	Homo sapiens	83.84	0.00e+00	1529.00
IUUC-Itr-048414	Ictidomys tridecemlineatus	83.12	0.00e+00	1570.00
IUUC-Lch-049764	Latimeria chalumnae	60.33	0.00e+00	1033.00
IUUC-Loc-052143	Lepisosteus oculatus	55.10	0.00e+00	1010.00
IUUC-Laf-053503	Loxodonta africana	82.37	0.00e+00	1506.00
IUUC-Mcc-054992	Macaca mulatta	82.79	0.00e+00	1523.00
IUUC-Meu-056406	Macropus eugenii	62.73	0.00e+00	1109.00
IUUC-Mga-059351	Meleagris gallopavo	62.97	0.00e+00	1197.00
IUUC-Mmr-061537	Microcebus murinus	83.11	0.00e+00	1447.00
IUUC-Mdo-061832	Monodelphis domestica	65.85	0.00e+00	1097.00
IUUC-Mmu-064282	Mus musculus	79.32	0.00e+00	1462.00
IUUC-Mpu-066399	Mustela putorius furo	90.14	0.00e+00	1622.00
IUUC-Mlu-067265	Myotis lucifugus	83.40	0.00e+00	1475.00
IUUC-Nle-069078	Nomascus leucogenys	83.11	0.00e+00	1518.00
IUUC-Opr-070946	Ochotona princeps	73.51	0.00e+00	1321.00
IUUC-Ont-071355	Oreochromis niloticus	49.79	0.00e+00	894.00
IUUC-Oan-072937	Ornithorhynchus anatinus	74.30	0.00e+00	1382.00
IUUC-Ocu-073815	Oryctolagus cuniculus	80.69	0.00e+00	1511.00
IUUC-Ola-087381	Oryzias latipes	49.35	0.00e+00	862.00
IUUC-Oga-088725	Otolemur garnettii	82.06	0.00e+00	1518.00
IUUC-Oar-090401	Ovis aries	82.38	0.00e+00	1543.00
IUUC-Ptr-090590	Pan troglodytes	83.63	0.00e+00	1524.00
IUUC-Pan-091765	Papio anubis	83.21	0.00e+00	1530.00
IUUC-Psi-093182	Pelodiscus sinensis	63.57	0.00e+00	1188.00
IUUC-Pfo-097422	Poecilia formosa	48.41	0.00e+00	871.00
IUUC-Pab-098289	Pongo abelii	83.84	0.00e+00	1526.00
IUUC-Pca-100165	Procavia capensis	73.86	0.00e+00	1024.00
IUUC-Pva-102943	Pteropus vampyrus	87.30	0.00e+00	1588.00
IUUC-Rno-104930	Rattus norvegicus	79.01	0.00e+00	1481.00
IUUC-Sha-106800	Sarcophilus harrisii	48.49	0.00e+00	674.00
IUUC-Sar-113205	Sorex araneus	72.24	0.00e+00	992.00
IUUC-Ssc-115910	Sus scrofa	84.50	0.00e+00	1347.00
IUUC-Tgu-117179	Taeniopygia guttata	64.14	0.00e+00	1187.00
IUUC-Tru-118220	Takifugu rubripes	49.15	0.00e+00	859.00
IUUC-Tsy-119418	Tarsius syrichta	80.17	0.00e+00	1191.00
IUUC-Tni-120033	Tetraodon nigroviridis	49.82	2.00e-67	249.00
IUUC-Tbe-127308	Tupaia belangeri	89.92	0.00e+00	666.00
IUUC-Ttr-129233	Tursiops truncatus	85.31	0.00e+00	1547.00
IUUC-Vpa-130620	Vicugna pacos	81.67	2.00e-110	394.00
IUUC-Vvi-131328	Vitis vinifera	32.93	8.40e-02	32.70
IUUC-Xtr-132075	Xenopus tropicalis	53.37	0.00e+00	1003.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence