iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052309

Ensembl Protein ID

ENSLOCP00000006608.1

UniProt Accession

W5MDZ9; W5MDZ9_LEPOC

Genbank Protein ID

ENSLOCP00000006608

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AHAT01004425

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000005468.1	ENSLOCT00000006616.1	ENSLOCP00000006608.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.70e-17	62.6	69	125

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + v +ly+yea ++d+L +kkG++++v+   e+ ++W+k+++ ++ k+G++P+n+v++++
   Q: 69   KIVVALYPYEAIHQDDLGFKKGEKLKVL---EEHGEWWKAKSLTSRKEGFIPSNYVAQVN 125
           6799************************...999***********************997 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MGCKKSKLTG PETGGGLVKK NQSVRTERTI YVRDPTSNKQ HAINSSNRDS RLLPGQVFQK 60
LEEQQETGKI VVALYPYEAI HQDDLGFKKG EKLKVLEEHG EWWKAKSLTS RKEGFIPSNY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGATGTA AAAAATCCAA GCTGACAGGC CCGGAGACTG GTGGTGGACT TGTGAAGAAA 60
AACCAATCAG TACGTACTGA ACGAACTATA TATGTGAGAG ATCCAACCTC CAATAAACAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0090022--P:regulation of neutrophil chemotaxis
GO:0009611--P:response to wounding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001812	Ailuropoda melanoleuca	77.52	0.00e+00	835.00
IUUC-Apl-004139	Anas platyrhynchos	78.85	0.00e+00	845.00
IUUC-Aca-004333	Anolis carolinensis	78.57	0.00e+00	840.00
IUUC-Ame-011257	Astyanax mexicanus	87.40	0.00e+00	940.00
IUUC-Bta-013257	Bos taurus	77.52	0.00e+00	838.00
IUUC-Cja-018827	Callithrix jacchus	78.29	0.00e+00	842.00
IUUC-Cfa-020816	Canis familiaris	77.91	0.00e+00	838.00
IUUC-Cpo-021423	Cavia porcellus	78.10	0.00e+00	840.00
IUUC-Csa-024244	Chlorocebus sabaeus	77.91	0.00e+00	838.00
IUUC-Dre-028518	Danio rerio	85.49	0.00e+00	913.00
IUUC-Dno-029322	Dasypus novemcinctus	78.49	0.00e+00	844.00
IUUC-Dor-030706	Dipodomys ordii	74.73	0.00e+00	739.00
IUUC-Eca-034193	Equus caballus	77.91	0.00e+00	842.00
IUUC-Fal-037273	Ficedula albicollis	79.46	0.00e+00	853.00
IUUC-Gmo-039677	Gadus morhua	82.52	0.00e+00	790.00
IUUC-Gga-040417	Gallus gallus	76.89	0.00e+00	825.00
IUUC-Gac-042490	Gasterosteus aculeatus	79.26	0.00e+00	868.00
IUUC-Ggo-045096	Gorilla gorilla	78.10	0.00e+00	841.00
IUUC-Hsa-046214	Homo sapiens	78.10	0.00e+00	841.00
IUUC-Itr-048354	Ictidomys tridecemlineatus	78.10	0.00e+00	842.00
IUUC-Lch-049991	Latimeria chalumnae	80.62	0.00e+00	848.00
IUUC-Laf-053568	Loxodonta africana	78.10	0.00e+00	840.00
IUUC-Mcc-054849	Macaca mulatta	77.91	0.00e+00	838.00
IUUC-Meu-056170	Macropus eugenii	65.63	0.00e+00	673.00
IUUC-Mmr-061519	Microcebus murinus	77.71	0.00e+00	839.00
IUUC-Mdo-062090	Monodelphis domestica	70.49	0.00e+00	774.00
IUUC-Mmu-063760	Mus musculus	77.91	0.00e+00	838.00
IUUC-Mpu-065677	Mustela putorius furo	77.52	0.00e+00	837.00
IUUC-Mlu-067386	Myotis lucifugus	77.91	0.00e+00	839.00
IUUC-Nle-069742	Nomascus leucogenys	77.91	0.00e+00	839.00
IUUC-Ont-071537	Oreochromis niloticus	81.01	0.00e+00	884.00
IUUC-Oan-073193	Ornithorhynchus anatinus	79.07	0.00e+00	850.00
IUUC-Ocu-074501	Oryctolagus cuniculus	78.10	0.00e+00	842.00
IUUC-Ola-086726	Oryzias latipes	80.04	0.00e+00	870.00
IUUC-Oga-088069	Otolemur garnettii	76.64	0.00e+00	829.00
IUUC-Oar-090091	Ovis aries	77.52	0.00e+00	838.00
IUUC-Ptr-091409	Pan troglodytes	78.10	0.00e+00	841.00
IUUC-Pan-092268	Papio anubis	77.91	0.00e+00	839.00
IUUC-Psi-093685	Pelodiscus sinensis	79.42	0.00e+00	854.00
IUUC-Pfo-096217	Poecilia formosa	79.84	0.00e+00	880.00
IUUC-Pab-098601	Pongo abelii	78.10	0.00e+00	840.00
IUUC-Rno-105557	Rattus norvegicus	78.10	0.00e+00	842.00
IUUC-Sha-106643	Sarcophilus harrisii	76.94	0.00e+00	832.00
IUUC-Ssc-116317	Sus scrofa	72.92	0.00e+00	768.00
IUUC-Tgu-116865	Taeniopygia guttata	79.46	0.00e+00	853.00
IUUC-Tru-118284	Takifugu rubripes	79.11	0.00e+00	858.00
IUUC-Tsy-119440	Tarsius syrichta	80.51	0.00e+00	802.00
IUUC-Tni-120005	Tetraodon nigroviridis	77.52	0.00e+00	851.00
IUUC-Ttr-128481	Tursiops truncatus	72.16	0.00e+00	690.00
IUUC-Xtr-131907	Xenopus tropicalis	71.98	0.00e+00	746.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence