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Tag Content
UUCD2 ID IUUC-Dre-027730
UUCD1 version UUC-DaR-00847
Ensembl Protein ID ENSDARP00000122396.1
UniProt Accession F1QT71; F1QT71_DANRE
Genbank Protein ID ENSDARP00000122396
Protein Name Ubiquitin protein ligase E3 component n-recognin 5
Genbank Nucleotide ID CR293507
Gene Name ubr5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000018192.10 ENSDART00000134444.2 ENSDARP00000122396.1
ENSDARG00000018192.10 ENSDART00000141985.1 ENSDARP00000112650.1
ENSDARG00000018192.10 ENSDART00000111869.3 ENSDARP00000101390.3
ENSDARG00000018192.10 ENSDART00000128437.2 ENSDARP00000111743.2
ENSDARG00000018192.10 ENSDART00000035761.8 ENSDARP00000033510.7
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 1.90e-76 258.6 2498 2821
Active Site
Position(s) Description Evidence
2791 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 16   EegldlgGvtreflallskelqnpd..lglf.lysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfykl 99
           +e+ + +G+tr ++++ +++  + d  ++lf +  +++ ++ +p +++      +l++F+ +Gr+lg++l +++l++++l+++++k 
   Q: 2498 QENRKRHGSTRSVVDMELDDPDDGDdnAPLFyQPGKRGFYSPRPGKNTE----ARLNCFRNIGRILGLCLLQNELCPITLNRHVIKV 2580
           5667778999999888888888877777888233333666666666654....89******************************** PP
   S: 100  llgkklsledleevdpelykslkeikena...esdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlk 183
           llg+k++++d++ +dp +y+sl ++ ++    e++   +++dl+f ++ ++ + + ++eL++gG n+pVt  N +eYv++++e+r+ 
   Q: 2581 LLGRKVNWHDFAFFDPVMYESLRQLIRHSqteEAEAVFAAMDLAFAIDLCKEEGAGQVELLSGGVNMPVTPLNVYEYVRRYAEHRML 2667
           *********************7776655535555888899*********************************************** PP
   S: 184  egikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspai....qwFwevleefsseerkafLq 266
              ++ ++a+r+G+ +v+p++ l+ +t+e+++ll++G+ e++v++l ++t+++++  e+ +++    +wFw+++e++s++er++++ 
   Q: 2668 VVAEQPLHAMRKGLLDVLPKNALEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLlqfkRWFWSIVEKMSMTERQDLVY 2754
           ****************************************************9999999999989999******************* PP
   S: 267  FvTgssrlPl..gGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           F+T+s++lP+  +Gf++++  +++ir   +d++lP++nTC+++L +P Yssk+ilk+kLl+Ai++ k+F++
   Q: 2755 FWTSSPSLPAseEGFQPMP--SITIRP-PDDQHLPTANTCISRLYVPLYSSKQILKQKLLLAIKT-KNFGF 2821
           **********999******..799999.99**********************************9.99875 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MTSIHFVVHP LPGTEDQLND RLREVSEKLN KYNCNSHPHL IPLEQAKLKQ CVVGPNHAGF 60
LLEDGRICRI SFAVQPDRLE LGKPDGNDGS KLSSVSGAGR SSRPGRTSDP PWFLSGSDTL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-027730|E3,HECT|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCGGCATGT GGATGAGGAG GTTGTATATT TCAGCTCTTC TGTTGTTTTT GGCGAAGAAA 60
ACACACATTC TCAAAACGAA CCCGTAAAAA ATAAGAAAAA AAGCCCCACA CAAAATCATT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-027730|E3,HECT|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR024725--E3_UbLigase_EDD_UBA
IPR000569--HECT_dom
IPR002004--PABP_HYD
IPR009091--RCC1/BLIP-II
IPR003126--Znf_UBR
PROSITE

PS50237--HECT
PS51309--PABC
PS51157--ZF_UBR
Pfam

PF11547--E3_UbLigase_EDD
PF00632--HECT
PF00658--PABP
SMART

SM00119--HECTc
SM00517--PolyA
SM00396--ZnF_UBR1
Gene Ontology

GO:0003723--F:RNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002217 Ailuropoda melanoleuca 89.17 0.00e+00 3890.00
IUUC-Apl-004165 Anas platyrhynchos 89.32 0.00e+00 3887.00
IUUC-Aca-004577 Anolis carolinensis 88.36 0.00e+00 3538.00
IUUC-Ame-010702 Astyanax mexicanus 93.59 0.00e+00 2712.00
IUUC-Bta-012313 Bos taurus 88.45 0.00e+00 4118.00
IUUC-Cel-018165 Caenorhabditis elegans 27.10 9.00e-83 303.00
IUUC-Cja-019858 Callithrix jacchus 88.44 0.00e+00 4108.00
IUUC-Cfa-020973 Canis familiaris 88.41 0.00e+00 4118.00
IUUC-Cpo-022108 Cavia porcellus 90.42 0.00e+00 1735.00
IUUC-Csa-023985 Chlorocebus sabaeus 88.34 0.00e+00 4156.00
IUUC-Cho-025034 Choloepus hoffmanni 78.96 0.00e+00 914.00
IUUC-Cin-025715 Ciona intestinalis 41.36 0.00e+00 868.00
IUUC-Csv-026131 Ciona savignyi 46.67 0.00e+00 669.00
IUUC-Dno-029123 Dasypus novemcinctus 86.93 0.00e+00 3773.00
IUUC-Dor-030757 Dipodomys ordii 85.17 0.00e+00 2554.00
IUUC-Dme-032192 Drosophila melanogaster 52.15 3.00e-174 607.00
IUUC-Ete-032292 Echinops telfairi 85.71 0.00e+00 1869.00
IUUC-Eca-034347 Equus caballus 89.27 0.00e+00 3864.00
IUUC-Eeu-034873 Erinaceus europaeus 84.38 0.00e+00 3875.00
IUUC-Fca-036485 Felis catus 87.67 0.00e+00 3793.00
IUUC-Fal-037071 Ficedula albicollis 89.73 0.00e+00 3898.00
IUUC-Gmo-039589 Gadus morhua 92.49 0.00e+00 4182.00
IUUC-Gga-041195 Gallus gallus 88.56 0.00e+00 3817.00
IUUC-Gac-042538 Gasterosteus aculeatus 92.70 0.00e+00 4187.00
IUUC-Ggo-045351 Gorilla gorilla 88.99 0.00e+00 3967.00
IUUC-Hsa-045941 Homo sapiens 88.56 0.00e+00 4177.00
IUUC-Itr-048635 Ictidomys tridecemlineatus 88.30 0.00e+00 4069.00
IUUC-Lch-050480 Latimeria chalumnae 89.72 0.00e+00 3902.00
IUUC-Loc-052664 Lepisosteus oculatus 90.65 0.00e+00 4132.00
IUUC-Laf-053960 Loxodonta africana 87.06 0.00e+00 1398.00
IUUC-Mcc-054703 Macaca mulatta 88.34 0.00e+00 4149.00
IUUC-Meu-056431 Macropus eugenii 80.58 0.00e+00 715.00
IUUC-Mga-059289 Meleagris gallopavo 88.88 0.00e+00 3255.00
IUUC-Mmr-061737 Microcebus murinus 87.91 0.00e+00 4007.00
IUUC-Mdo-062499 Monodelphis domestica 89.54 0.00e+00 3882.00
IUUC-Mmu-063273 Mus musculus 87.95 0.00e+00 4046.00
IUUC-Mpu-066907 Mustela putorius furo 89.01 0.00e+00 3763.00
IUUC-Mlu-067942 Myotis lucifugus 88.85 0.00e+00 3916.00
IUUC-Nle-069527 Nomascus leucogenys 88.33 0.00e+00 4130.00
IUUC-Opr-070626 Ochotona princeps 79.42 0.00e+00 1273.00
IUUC-Ont-071951 Oreochromis niloticus 93.64 0.00e+00 4214.00
IUUC-Oan-072958 Ornithorhynchus anatinus 89.16 0.00e+00 3752.00
IUUC-Ocu-074503 Oryctolagus cuniculus 87.55 0.00e+00 3817.00
IUUC-Ola-086757 Oryzias latipes 92.30 0.00e+00 4258.00
IUUC-Oga-088781 Otolemur garnettii 88.27 0.00e+00 4108.00
IUUC-Oar-089274 Ovis aries 88.16 0.00e+00 4063.00
IUUC-Ptr-090669 Pan troglodytes 89.21 0.00e+00 3606.00
IUUC-Pan-092226 Papio anubis 88.03 0.00e+00 4140.00
IUUC-Psi-093502 Pelodiscus sinensis 89.29 0.00e+00 3881.00
IUUC-Pma-094454 Petromyzon marinus 82.12 0.00e+00 727.00
IUUC-Pfo-096173 Poecilia formosa 93.36 0.00e+00 3919.00
IUUC-Pab-098355 Pongo abelii 90.38 0.00e+00 2844.00
IUUC-Pca-100570 Procavia capensis 89.72 0.00e+00 1005.00
IUUC-Pva-102572 Pteropus vampyrus 86.22 0.00e+00 1176.00
IUUC-Rno-104916 Rattus norvegicus 87.15 0.00e+00 3539.00
IUUC-Sha-106653 Sarcophilus harrisii 89.48 0.00e+00 3888.00
IUUC-Sar-113517 Sorex araneus 80.66 0.00e+00 1171.00
IUUC-Ssc-115470 Sus scrofa 89.24 0.00e+00 2281.00
IUUC-Tgu-116932 Taeniopygia guttata 89.47 0.00e+00 3878.00
IUUC-Tru-117682 Takifugu rubripes 94.82 0.00e+00 2765.00
IUUC-Tsy-119417 Tarsius syrichta 85.41 0.00e+00 2226.00
IUUC-Tni-120442 Tetraodon nigroviridis 89.14 0.00e+00 3850.00
IUUC-Tbe-127456 Tupaia belangeri 82.38 0.00e+00 1126.00
IUUC-Ttr-128606 Tursiops truncatus 90.28 0.00e+00 1234.00
IUUC-Vpa-130112 Vicugna pacos 86.21 0.00e+00 3326.00
IUUC-Xtr-131929 Xenopus tropicalis 85.88 0.00e+00 3989.00
Created Date 25-Jun-2017

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