iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036445

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02173504

Gene Name

KLHL28

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000023398.1	ENSFCAT00000030134.1	ENSFCAP00000022965.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.50e-18	65.4	36	99
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.50e-12	46.6	135	166

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +D++l vg+++++ahk+vLa+ S++F+a+f+++l+e++ +++ve++ ++ ++++a++++ Ytg++
   Q: 36   CDIVLRVGDVKIHAHKVVLASISPYFKAMFTGNLSEKE-NSEVEFQCIDETALQAIVEYAYTGTV 99
           8***********************************97.************************87 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nc+gi rfA++y+c+dL++aa ++i+++F+
   Q: 135  PGNCIGISRFAETYGCHDLYLAATKYICQNFE 166
           56*****************************5 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MMDHTSPTYM LANLTHLHSE QLLQGLNLLR QHHELCDIVL RVGDVKIHAH KVVLASISPY 60
FKAMFTGNLS EKENSEVEFQ CIDETALQAI VEYAYTGTVF ISQDTVESLL PAANLLQIKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAGAACTTG GGAAGCCAAG TTAGTAAGTG GAGGTTGTGT GGTAATCATG GAATCAAAGA 60
AAAGGAACTT GGAACGTCTT GAATGATGTA CCATCATCAA AGTTATGGTA GAAGTTTTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030569--KLHL28
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001581	Ailuropoda melanoleuca	99.12	0.00e+00	1188.00
IUUC-Apl-003577	Anas platyrhynchos	92.79	0.00e+00	1090.00
IUUC-Aca-004320	Anolis carolinensis	86.95	0.00e+00	924.00
IUUC-Ame-011433	Astyanax mexicanus	84.76	0.00e+00	985.00
IUUC-Bta-012650	Bos taurus	99.47	0.00e+00	1192.00
IUUC-Cja-019878	Callithrix jacchus	98.95	0.00e+00	1190.00
IUUC-Cfa-020936	Canis familiaris	99.65	0.00e+00	1193.00
IUUC-Cpo-022212	Cavia porcellus	97.72	0.00e+00	1177.00
IUUC-Csa-023372	Chlorocebus sabaeus	99.30	0.00e+00	1192.00
IUUC-Cho-024885	Choloepus hoffmanni	98.33	2.00e-174	605.00
IUUC-Dno-029895	Dasypus novemcinctus	97.72	0.00e+00	1176.00
IUUC-Ete-032703	Echinops telfairi	97.76	0.00e+00	917.00
IUUC-Eca-034150	Equus caballus	99.30	0.00e+00	1190.00
IUUC-Eeu-035233	Erinaceus europaeus	97.02	0.00e+00	1167.00
IUUC-Fal-037156	Ficedula albicollis	82.66	0.00e+00	999.00
IUUC-Gmo-039158	Gadus morhua	84.94	0.00e+00	1016.00
IUUC-Gga-040855	Gallus gallus	92.82	0.00e+00	1121.00
IUUC-Gac-041294	Gasterosteus aculeatus	84.24	0.00e+00	1008.00
IUUC-Ggo-045399	Gorilla gorilla	98.77	0.00e+00	1185.00
IUUC-Hsa-046199	Homo sapiens	98.77	0.00e+00	1185.00
IUUC-Itr-048859	Ictidomys tridecemlineatus	98.60	0.00e+00	1182.00
IUUC-Lch-049445	Latimeria chalumnae	88.14	0.00e+00	811.00
IUUC-Loc-052737	Lepisosteus oculatus	86.34	0.00e+00	1010.00
IUUC-Laf-054173	Loxodonta africana	98.43	0.00e+00	1178.00
IUUC-Mcc-055000	Macaca mulatta	98.95	0.00e+00	1189.00
IUUC-Meu-056028	Macropus eugenii	87.29	1.00e-145	509.00
IUUC-Mga-059609	Meleagris gallopavo	92.66	0.00e+00	1118.00
IUUC-Mmr-060842	Microcebus murinus	99.12	0.00e+00	1189.00
IUUC-Mdo-062776	Monodelphis domestica	92.82	0.00e+00	1085.00
IUUC-Mmu-063720	Mus musculus	97.02	0.00e+00	1173.00
IUUC-Mpu-066594	Mustela putorius furo	68.40	0.00e+00	730.00
IUUC-Mlu-067403	Myotis lucifugus	97.20	0.00e+00	1168.00
IUUC-Nle-069242	Nomascus leucogenys	98.60	0.00e+00	1184.00
IUUC-Opr-070942	Ochotona princeps	98.66	4.00e-177	613.00
IUUC-Ont-072586	Oreochromis niloticus	85.11	0.00e+00	1014.00
IUUC-Oan-073070	Ornithorhynchus anatinus	93.60	0.00e+00	1080.00
IUUC-Ocu-074536	Oryctolagus cuniculus	98.25	0.00e+00	1179.00
IUUC-Ola-086669	Oryzias latipes	71.50	0.00e+00	822.00
IUUC-Oga-088974	Otolemur garnettii	98.77	0.00e+00	1187.00
IUUC-Oar-089544	Ovis aries	99.30	0.00e+00	1192.00
IUUC-Ptr-091478	Pan troglodytes	98.42	0.00e+00	1177.00
IUUC-Pan-092653	Papio anubis	99.12	0.00e+00	1191.00
IUUC-Psi-094014	Pelodiscus sinensis	93.35	0.00e+00	1127.00
IUUC-Pfo-097316	Poecilia formosa	84.76	0.00e+00	1009.00
IUUC-Pab-098609	Pongo abelii	98.60	0.00e+00	1183.00
IUUC-Pva-102527	Pteropus vampyrus	98.66	5.00e-176	610.00
IUUC-Rno-105188	Rattus norvegicus	97.37	0.00e+00	1176.00
IUUC-Sha-106543	Sarcophilus harrisii	93.35	0.00e+00	1092.00
IUUC-Sar-113507	Sorex araneus	96.32	0.00e+00	1164.00
IUUC-Ssc-115803	Sus scrofa	98.95	0.00e+00	1187.00
IUUC-Tgu-116661	Taeniopygia guttata	82.12	0.00e+00	912.00
IUUC-Tru-118738	Takifugu rubripes	82.09	0.00e+00	981.00
IUUC-Tsy-119570	Tarsius syrichta	91.59	0.00e+00	1077.00
IUUC-Tni-120041	Tetraodon nigroviridis	83.54	0.00e+00	1003.00
IUUC-Tbe-127655	Tupaia belangeri	91.26	0.00e+00	1060.00
IUUC-Ttr-129249	Tursiops truncatus	99.47	0.00e+00	1191.00
IUUC-Vpa-130034	Vicugna pacos	98.77	0.00e+00	1186.00
IUUC-Xtr-132964	Xenopus tropicalis	87.74	0.00e+00	1058.00
IUUC-Xma-133894	Xiphophorus maculatus	84.59	0.00e+00	1006.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence