iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lpe-051535

Ensembl Protein ID

LPERR03G33220.2

UniProt Accession

A0A0D9W0S4; A0A0D9W0S4_9ORYZ

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
LPERR03G33220	LPERR03G33220.1	LPERR03G33220.1
LPERR03G33220	LPERR03G33220.2	LPERR03G33220.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	6.40e-90	303.2	67	486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 70   gksKAevaaealkelnpdvnveaheesiteleeeiv.FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecysc 162
           g+s+A++++ +l+eln+ vn++++ees+ +l ++++ Ff++f+vV++++ ++ + +k++++c++a++ l+ ++++Gl G vr+++k++t+++s+
   Q: 67   GQSRAKSVCSFLQELNDAVNAKFVEESPLALIDTNPpFFSQFTVVIATQLPERSLLKLDSICREANIVLVAARSYGLTGLVRISVKEHTVIESK 160
           9**********************************9********************************************************** PP
   S: 163  sd...dppqktiPfctlketpn.........aaehtiewavlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavka 244
           +d   d++++ +P+ +lk++           +++++i+++ ++  l+e++a ++++  +++++ek+e+kd++++ + + deen++ea+e + k 
   Q: 161  PDhflDDLRLHNPWTELKQFAKstdisdkdpVVHKHIPYIIILVRLAEKWADAHDGHLPSTRQEKKEFKDLIREHMLNLDEENYKEAVESSYKV 254
           ********************99999999999*************************************************************** PP
   S: 245  fakttins.ikqllksfecdivtkskspfwv............................................................... 274
             +  i++ i+q++++ +  +v++s+s+fwv                                                               
   Q: 255  SVTPGISDdIRQIIDD-SSTEVSSSSSDFWVlvaalkefianevngelplegtipdmtslteyyvslqkiyqakaesdclalehhvkkilkrid 347
           ****************.66699************************************************************************ PP
   S: 275  ............sfcsnaealq...........vpekvekdeevvkasap.....lylllralerfekkkgrkpgelsfekdddsavdlvtaaa 340
                        fc+na++l+             +   + +++++++++     +y+llra++r++++++r pg ++ e d+d +++l+taa 
   Q: 348  rdpdsisrayikAFCKNARKLRvcryrsieeefGSPLLSEVQKYFTDEDYcfamnFYVLLRAVDRLAANYNRFPGIFDSEIDED-VPRLKTAAV 440
           **********************665555555553367777777777777788888*******************9999999999.******888 PP
   S: 341  nlraeslgiep.kldddlikeiagniipaiattnavvgGlaaqEviK 386
           +  ++++g+++  l++dli+e+++++ ++i++++a++gG+a+qEviK
   Q: 441  SV-MSEMGLNGaSLSEDLITEMCRFGGAEIHPVAAFIGGVASQEVIK 486
           75.6******************************************9 PP

Organism

Leersia perrieri

Functional Description
(View)

Regulatory subunit of the dimeric E1 enzyme. E1 activates RUB1/NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a RUB1-ECR1 thioester and free AMP. E1 finally transfers RUB1 to the catalytic cysteine of RCE1.

Protein Sequence
(Fasta)

MAAAAAAFAE PKTKYDRQLR IWGDQGQAAL EKADICLLTC GPTGTEAMKN LVLGGVGSVT 60
IVDGCLGQSR AKSVCSFLQE LNDAVNAKFV EESPLALIDT NPPFFSQFTV VIATQLPERS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCTTTCTT CTAGCTCCAC TTCAGCTTCC GCTTTATTCC TTCTCCGGGG AGAGAAGAAG 60
GCGAAGGGAG CAAAACCCAA AAAGCCTCAC GCAGAGAGGT GACCGCGCCG CCGGAATCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	83.37	0.00e+00	835.00
IUUC-Aml-002333	Ailuropoda melanoleuca	41.48	3.00e-112	398.00
IUUC-Atr-002644	Amborella trichopoda	68.62	0.00e+00	671.00
IUUC-Apl-003446	Anas platyrhynchos	40.97	6.00e-104	370.00
IUUC-Aca-004450	Anolis carolinensis	41.08	2.00e-110	392.00
IUUC-Aly-005466	Arabidopsis lyrata	64.24	0.00e+00	672.00
IUUC-Ath-006692	Arabidopsis thaliana	64.24	0.00e+00	669.00
IUUC-Ago-007900	Ashbya gossypii	27.79	4.00e-35	141.00
IUUC-Acl-008333	Aspergillus clavatus	30.46	5.00e-52	198.00
IUUC-Afl-008529	Aspergillus flavus	31.87	3.00e-57	215.00
IUUC-Afu-009071	Aspergillus fumigatus	30.78	1.00e-51	197.00
IUUC-Ani-009443	Aspergillus nidulans	29.83	2.00e-45	176.00
IUUC-Ang-009669	Aspergillus niger	30.10	9.00e-55	207.00
IUUC-Aor-009914	Aspergillus oryzae	31.57	3.00e-55	208.00
IUUC-Ate-010450	Aspergillus terreus	30.73	8.00e-54	204.00
IUUC-Ame-011183	Astyanax mexicanus	39.03	2.00e-106	379.00
IUUC-Bgr-012111	Blumeria graminis	31.30	6.00e-44	171.00
IUUC-Bta-012583	Bos taurus	41.45	8.00e-113	400.00
IUUC-Bci-013892	Botrytis cinerea	29.94	6.00e-40	157.00
IUUC-Bdi-014592	Brachypodium distachyon	84.10	0.00e+00	842.00
IUUC-Bol-016401	Brassica oleracea	64.63	0.00e+00	666.00
IUUC-Bra-017506	Brassica rapa	62.90	0.00e+00	646.00
IUUC-Cel-018456	Caenorhabditis elegans	28.87	4.00e-56	211.00
IUUC-Cja-020007	Callithrix jacchus	42.00	1.00e-112	399.00
IUUC-Cfa-020324	Canis familiaris	41.65	4.00e-114	404.00
IUUC-Cpo-022248	Cavia porcellus	39.82	4.00e-66	244.00
IUUC-Csa-023149	Chlorocebus sabaeus	40.61	6.00e-93	333.00
IUUC-Cho-024537	Choloepus hoffmanni	35.71	2.00e-78	285.00
IUUC-Cin-025763	Ciona intestinalis	39.45	2.00e-92	332.00
IUUC-Csv-026113	Ciona savignyi	37.66	1.00e-85	310.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	28.49	1.00e-41	163.00
IUUC-Cne-026884	Cryptococcus neoformans	30.24	5.00e-52	198.00
IUUC-Dre-028140	Danio rerio	40.83	2.00e-111	395.00
IUUC-Dno-030033	Dasypus novemcinctus	40.96	3.00e-102	364.00
IUUC-Dor-030513	Dipodomys ordii	32.92	6.00e-30	124.00
IUUC-Dse-031536	Dothistroma septosporum	28.92	6.00e-48	184.00
IUUC-Dme-031683	Drosophila melanogaster	36.00	4.00e-79	288.00
IUUC-Ete-032420	Echinops telfairi	36.51	3.00e-94	338.00
IUUC-Eca-033992	Equus caballus	40.77	7.00e-92	330.00
IUUC-Eeu-034713	Erinaceus europaeus	33.17	4.00e-30	125.00
IUUC-Fca-036548	Felis catus	40.98	6.00e-114	404.00
IUUC-Fal-037600	Ficedula albicollis	39.96	1.00e-100	360.00
IUUC-Fox-038037	Fusarium oxysporum	29.13	8.00e-51	194.00
IUUC-Fso-038387	Fusarium solani	29.28	1.00e-51	197.00
IUUC-Gmo-038562	Gadus morhua	39.92	7.00e-105	374.00
IUUC-Ggr-040005	Gaeumannomyces graminis	33.25	2.00e-48	186.00
IUUC-Gga-041129	Gallus gallus	40.85	1.00e-104	372.00
IUUC-Gac-042558	Gasterosteus aculeatus	40.52	6.00e-108	384.00
IUUC-Gma-043610	Glycine max	66.60	0.00e+00	662.00
IUUC-Ggo-045611	Gorilla gorilla	41.40	1.00e-111	396.00
IUUC-Hsa-046563	Homo sapiens	41.65	8.00e-113	400.00
IUUC-Hvu-047790	Hordeum vulgare	87.29	0.00e+00	636.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	42.05	1.00e-112	399.00
IUUC-Kpa-049309	Komagataella pastoris	34.53	4.00e-63	234.00
IUUC-Lch-050038	Latimeria chalumnae	40.96	9.00e-108	383.00
IUUC-Loc-051917	Lepisosteus oculatus	37.57	3.00e-98	351.00
IUUC-Lma-053112	Leptosphaeria maculans	31.02	4.00e-56	211.00
IUUC-Laf-053690	Loxodonta africana	42.45	4.00e-115	407.00
IUUC-Mcc-055117	Macaca mulatta	41.32	3.00e-112	398.00
IUUC-Meu-056761	Macropus eugenii	34.87	8.00e-84	303.00
IUUC-Mor-057230	Magnaporthe oryzae	30.19	8.00e-52	197.00
IUUC-Mpo-057514	Magnaporthe poae	32.23	4.00e-46	178.00
IUUC-Mtr-058551	Medicago truncatula	64.31	0.00e+00	647.00
IUUC-Mla-059183	Melampsora laricipopulina	32.68	3.00e-68	252.00
IUUC-Mga-060144	Meleagris gallopavo	40.08	8.00e-101	360.00
IUUC-Mvi-060221	Microbotryum violaceum	31.73	7.00e-49	187.00
IUUC-Mmr-061325	Microcebus murinus	41.04	1.00e-111	396.00
IUUC-Mdo-062532	Monodelphis domestica	41.65	2.00e-112	398.00
IUUC-Mmu-063956	Mus musculus	41.25	1.00e-112	399.00
IUUC-Mac-064521	Musa acuminata	70.71	0.00e+00	721.00
IUUC-Mpu-066716	Mustela putorius furo	41.06	9.00e-111	393.00
IUUC-Mlu-067459	Myotis lucifugus	42.17	1.00e-114	405.00
IUUC-Nfi-068245	Neosartorya fischeri	30.65	5.00e-52	198.00
IUUC-Ncr-068910	Neurospora crassa	29.38	3.00e-49	188.00
IUUC-Nle-070034	Nomascus leucogenys	40.73	1.00e-107	383.00
IUUC-Opr-070552	Ochotona princeps	37.96	1.00e-91	329.00
IUUC-Ont-071426	Oreochromis niloticus	40.72	6.00e-110	390.00
IUUC-Oan-073389	Ornithorhynchus anatinus	38.46	9.00e-81	293.00
IUUC-Ocu-074911	Oryctolagus cuniculus	42.25	3.00e-114	405.00
IUUC-Oba-075437	Oryza barthii	89.68	0.00e+00	874.00
IUUC-Obr-076684	Oryza brachyantha	87.68	0.00e+00	808.00
IUUC-Ogl-077170	Oryza glaberrima	89.68	0.00e+00	874.00
IUUC-Ogu-078844	Oryza glumaepatula	89.07	0.00e+00	866.00
IUUC-Oin-079105	Oryza indica	89.47	0.00e+00	871.00
IUUC-Olo-080943	Oryza longistaminata	91.31	0.00e+00	877.00
IUUC-Oni-082891	Oryza nivara	93.54	0.00e+00	871.00
IUUC-Opu-083457	Oryza punctata	89.68	0.00e+00	877.00
IUUC-Oru-084960	Oryza rufipogon	91.31	0.00e+00	877.00
IUUC-Osa-085358	Oryza sativa	89.07	0.00e+00	865.00
IUUC-Ola-086420	Oryzias latipes	39.54	1.00e-69	256.00
IUUC-Olu-087625	Ostreococcus lucimarinus	30.19	1.00e-52	200.00
IUUC-Oga-088810	Otolemur garnettii	41.85	2.00e-113	402.00
IUUC-Oar-089196	Ovis aries	41.20	5.00e-111	394.00
IUUC-Ptr-090617	Pan troglodytes	41.65	5.00e-113	400.00
IUUC-Pan-092761	Papio anubis	41.85	5.00e-114	404.00
IUUC-Psi-093191	Pelodiscus sinensis	38.95	1.00e-105	376.00
IUUC-Pma-094380	Petromyzon marinus	39.52	2.00e-99	355.00
IUUC-Pno-095084	Phaeosphaeria nodorum	28.43	2.00e-46	181.00
IUUC-Ppa-095798	Physcomitrella patens	54.49	1.00e-155	542.00
IUUC-Pfo-096467	Poecilia formosa	41.07	1.00e-106	379.00
IUUC-Pab-098255	Pongo abelii	42.03	3.00e-97	347.00
IUUC-Pop-099722	Populus trichocarpa	67.61	0.00e+00	698.00
IUUC-Pca-100807	Procavia capensis	48.39	3.00e-45	175.00
IUUC-Ppe-101280	Prunus persica	67.41	0.00e+00	691.00
IUUC-Pva-102333	Pteropus vampyrus	40.40	3.00e-108	385.00
IUUC-Pgr-103401	Puccinia graminis	27.33	6.00e-51	194.00
IUUC-Ptt-103889	Puccinia triticina	24.09	3.00e-42	166.00
IUUC-Pte-104355	Pyrenophora teres	31.39	1.00e-55	210.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	31.52	1.00e-55	210.00
IUUC-Rno-105810	Rattus norvegicus	41.05	1.00e-111	395.00
IUUC-Sce-106397	Saccharomyces cerevisiae	29.97	9.00e-31	127.00
IUUC-Sha-106770	Sarcophilus harrisii	45.80	2.00e-63	234.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	33.54	4.00e-69	254.00
IUUC-Spo-108276	Schizosaccharomyces pombe	32.93	1.00e-69	256.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	30.92	3.00e-42	165.00
IUUC-Smo-109296	Selaginella moellendorffii	52.54	9.00e-148	516.00
IUUC-Sit-110157	Setaria italica	83.60	0.00e+00	847.00
IUUC-Sly-111660	Solanum lycopersicum	66.33	0.00e+00	677.00
IUUC-Stu-112469	Solanum tuberosum	65.75	0.00e+00	676.00
IUUC-Sar-113083	Sorex araneus	37.07	8.00e-37	147.00
IUUC-Sbi-113813	Sorghum bicolor	84.82	0.00e+00	858.00
IUUC-Sre-115058	Sporisorium reilianum	31.83	2.00e-54	206.00
IUUC-Tgu-116772	Taeniopygia guttata	41.00	4.00e-102	364.00
IUUC-Tru-118686	Takifugu rubripes	39.48	3.00e-109	388.00
IUUC-Tsy-119111	Tarsius syrichta	42.59	1.00e-56	213.00
IUUC-Tni-120231	Tetraodon nigroviridis	38.42	5.00e-96	344.00
IUUC-Tca-121491	Theobroma cacao	68.02	0.00e+00	661.00
IUUC-Tre-122103	Trichoderma reesei	30.84	7.00e-56	211.00
IUUC-Tvi-122672	Trichoderma virens	29.45	9.00e-51	194.00
IUUC-Tae-125316	Triticum aestivum	84.21	0.00e+00	840.00
IUUC-Tur-126487	Triticum urartu	82.65	0.00e+00	812.00
IUUC-Tme-127097	Tuber melanosporum	32.17	5.00e-61	228.00
IUUC-Ttr-128465	Tursiops truncatus	38.40	4.00e-97	347.00
IUUC-Uma-129645	Ustilago maydis	30.86	4.00e-52	198.00
IUUC-Vda-129989	Verticillium dahliae	27.38	5.00e-33	134.00
IUUC-Vpa-130529	Vicugna pacos	39.00	5.00e-102	364.00
IUUC-Vvi-131059	Vitis vinifera	68.02	0.00e+00	701.00
IUUC-Xtr-132002	Xenopus tropicalis	41.88	3.00e-112	398.00
IUUC-Xma-133930	Xiphophorus maculatus	41.16	2.00e-110	391.00
IUUC-Yli-134505	Yarrowia lipolytica	31.59	8.00e-65	240.00
IUUC-Zma-135619	Zea mays	84.41	0.00e+00	810.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence