iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Yli-134505

Ensembl Protein ID

CAG78778

UniProt Accession

Q6C046; Q6C046_YARLI

Genbank Protein ID

CAG78778.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

CR382132

Gene Name

YALI0_F27863g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YALI0_F27863g	CAG78778	CAG78778

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.30e-69	232.5	21	494

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesitele 101
           YDRQ+rlw + +q++l+ a+v+l+G  ++++E+ KnL+l  vgs tvvD+  v+  +l+++F+f+ +++gksKA++a   l+eln d  ++   ++++++ 
   Q: 21   YDRQLRLWAASGQRALEDASVCLLGSSPVATETMKNLILPNVGSYTVVDGGNVTEDDLSANFFFDSDSIGKSKAQSASLLLNELNKDSTGSYLDQKPSKIV 121
           ****************************************************************************************************9 PP
   S: 102  eeiv.FfkkfdvVvlaldnrearrk...vnrlclnarvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlketpn........aaehtie 188
            ++  +f++f+++v+ + +++       + + ++++ +pl+ + + G++G+vrv++k+l++++ ++d   +++++ P+++l e++n        aa ++++
   Q: 122  ASNLsYFDQFSIIVASVSSFDKYSDleaLSEYLYSHYIPLVVISSAGFYGYVRVVMKELPIIDTHPDslVDLRLDSPWPELMEYVNnfpepetaAARDHVP 222
           88889************9998876511156779999************************************************9999999999******* PP
   S: 189  wavlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafaktti.ns.ikqllksfecdivtkskspfwv............. 274
           ++vl+ k+++++ +e+e+  ++++ ek+++k++v ++l++ d+en +ea++++ +  +k+++ +s i++l++  + d  t++ + fw              
   Q: 223  MIVLLLKTADKWIKEHEGGLPTKRDEKLAFKKQV-EALRQGDSENVDEAVAAVWRLYQKSNQvPSqIRDLFNLSAEDS-TDRDPTFWTlvealkdfvaetg 321
           **********************************.888999************9999887652568*******88888.999999999************* PP
   S: 275  ..................................sfcsnaealq..vpekvekdeevvkasaplylllralerfekkkgrkpgelsfekdddsavdlvtaa 339
                                             +f++ ++++   vpe+v++++ ++++   +  l r  ++ +  + ++ ++++ e+dd   +  v +a
   Q: 322  tfplsgtvpdfkaytkdyvdiqrvykdkankdlsRFKEIVATKVveVPETVIEEFSKNSR---FIHLARGTSLTHDISPESLAQITSEDDDLLKLYYVIRA 419
           *********************999999999888855554443333388888888886544...56688888888888888887777777776544444444 PP
   S: 340  anlra..............eslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           +   +               +lg+ +    ++ +e+a+++  +++ +++v+gG+a+qE++K++ ++++pl+n++lfd+
   Q: 420  SQ--MlggkqdafsimtktNELGVTA-DVVEYSQEVARYEGRELHNISSVIGGVASQEIVKILAKQYVPLNNTVLFDG 494
           43..2447888888777666677777.44567899*****************************************97 PP

Organism

Yarrowia lipolytica

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MHRDKRQRMS DSIPSQKDRK YDRQLRLWAA SGQRALEDAS VCLLGSSPVA TETMKNLILP 60
NVGSYTVVDG GNVTEDDLSA NFFFDSDSIG KSKAQSASLL LNELNKDSTG SYLDQKPSKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACCGTG ACAAACGCCA GCGAATGTCG GACTCAATTC CCAGCCAAAA AGACCGCAAG 60
TACGACCGTC AGCTACGACT ATGGGCCGCA TCGGGCCAAC GTGCACTCGA AGATGCGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

yli:YALI0F27863g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	34.74	5.00e-83	299.00
IUUC-Aml-002333	Ailuropoda melanoleuca	34.91	5.00e-86	309.00
IUUC-Atr-002644	Amborella trichopoda	31.48	1.00e-72	265.00
IUUC-Apl-003446	Anas platyrhynchos	34.04	7.00e-78	282.00
IUUC-Aca-004450	Anolis carolinensis	32.23	7.00e-83	299.00
IUUC-Aly-005466	Arabidopsis lyrata	33.89	2.00e-88	317.00
IUUC-Ath-006692	Arabidopsis thaliana	34.44	4.00e-90	323.00
IUUC-Ago-007900	Ashbya gossypii	27.93	5.00e-40	156.00
IUUC-Acl-008333	Aspergillus clavatus	34.18	6.00e-79	286.00
IUUC-Afl-008529	Aspergillus flavus	35.27	3.00e-82	296.00
IUUC-Afu-009071	Aspergillus fumigatus	33.88	3.00e-76	277.00
IUUC-Ani-009443	Aspergillus nidulans	34.69	3.00e-74	270.00
IUUC-Ang-009669	Aspergillus niger	33.45	8.00e-77	279.00
IUUC-Aor-009914	Aspergillus oryzae	34.95	5.00e-80	290.00
IUUC-Ate-010450	Aspergillus terreus	34.18	5.00e-78	283.00
IUUC-Ame-011183	Astyanax mexicanus	31.49	4.00e-81	293.00
IUUC-Bgr-012111	Blumeria graminis	37.07	8.00e-79	285.00
IUUC-Bta-012583	Bos taurus	36.00	7.00e-89	319.00
IUUC-Bci-013892	Botrytis cinerea	37.16	3.00e-79	286.00
IUUC-Bdi-014592	Brachypodium distachyon	34.49	5.00e-81	293.00
IUUC-Bol-016399	Brassica oleracea	34.92	1.00e-86	311.00
IUUC-Bra-017506	Brassica rapa	34.43	3.00e-83	300.00
IUUC-Cel-018456	Caenorhabditis elegans	30.31	3.00e-62	230.00
IUUC-Cja-020007	Callithrix jacchus	35.23	7.00e-86	308.00
IUUC-Cfa-020324	Canis familiaris	35.24	5.00e-87	312.00
IUUC-Cpo-022248	Cavia porcellus	33.82	1.00e-48	185.00
IUUC-Csa-023149	Chlorocebus sabaeus	32.15	1.00e-59	221.00
IUUC-Cho-024537	Choloepus hoffmanni	32.24	2.00e-27	115.00
IUUC-Cin-025763	Ciona intestinalis	34.23	5.00e-77	279.00
IUUC-Csv-026113	Ciona savignyi	33.65	1.00e-78	285.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	34.31	4.00e-77	280.00
IUUC-Cne-026884	Cryptococcus neoformans	28.46	1.00e-55	208.00
IUUC-Cme-027210	Cyanidioschyzon merolae	24.29	6.00e-14	70.50
IUUC-Dre-028140	Danio rerio	31.88	1.00e-81	295.00
IUUC-Dno-030033	Dasypus novemcinctus	36.89	3.00e-76	276.00
IUUC-Dor-030513	Dipodomys ordii	48.04	2.00e-25	108.00
IUUC-Dse-031536	Dothistroma septosporum	33.87	2.00e-72	264.00
IUUC-Dme-031683	Drosophila melanogaster	32.30	3.00e-71	260.00
IUUC-Ete-032420	Echinops telfairi	32.30	2.00e-69	254.00
IUUC-Eca-033992	Equus caballus	32.81	1.00e-58	218.00
IUUC-Eeu-034713	Erinaceus europaeus	50.51	1.00e-28	118.00
IUUC-Fca-036548	Felis catus	35.09	2.00e-86	310.00
IUUC-Fal-037600	Ficedula albicollis	34.01	2.00e-79	288.00
IUUC-Fox-038037	Fusarium oxysporum	34.91	6.00e-84	302.00
IUUC-Fso-038387	Fusarium solani	35.37	7.00e-85	305.00
IUUC-Gmo-038562	Gadus morhua	32.07	5.00e-79	286.00
IUUC-Ggr-040005	Gaeumannomyces graminis	36.24	6.00e-81	292.00
IUUC-Gga-041129	Gallus gallus	33.84	1.00e-80	291.00
IUUC-Gac-042558	Gasterosteus aculeatus	32.70	5.00e-81	293.00
IUUC-Gma-043610	Glycine max	32.43	8.00e-79	285.00
IUUC-Ggo-045611	Gorilla gorilla	34.66	6.00e-85	306.00
IUUC-Hsa-046563	Homo sapiens	35.05	7.00e-87	312.00
IUUC-Hvu-047790	Hordeum vulgare	32.63	1.00e-48	185.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	35.24	3.00e-86	310.00
IUUC-Kpa-049309	Komagataella pastoris	35.45	1.00e-81	294.00
IUUC-Lch-050038	Latimeria chalumnae	35.31	3.00e-84	303.00
IUUC-Lpe-051535	Leersia perrieri	31.59	1.00e-62	231.00
IUUC-Loc-051917	Lepisosteus oculatus	29.59	2.00e-67	247.00
IUUC-Lma-053112	Leptosphaeria maculans	36.49	7.00e-84	302.00
IUUC-Laf-053690	Loxodonta africana	35.62	4.00e-87	313.00
IUUC-Mcc-055117	Macaca mulatta	34.03	3.00e-82	297.00
IUUC-Meu-056761	Macropus eugenii	28.52	1.00e-53	202.00
IUUC-Mor-057230	Magnaporthe oryzae	36.02	1.00e-84	305.00
IUUC-Mpo-057514	Magnaporthe poae	34.58	2.00e-76	278.00
IUUC-Mtr-058551	Medicago truncatula	31.66	3.00e-78	283.00
IUUC-Mla-059183	Melampsora laricipopulina	34.38	6.00e-81	292.00
IUUC-Mga-060144	Meleagris gallopavo	33.14	3.00e-77	280.00
IUUC-Mvi-060221	Microbotryum violaceum	37.19	1.00e-65	241.00
IUUC-Mmr-061325	Microcebus murinus	34.47	1.00e-82	298.00
IUUC-Mdo-062532	Monodelphis domestica	35.62	1.00e-87	314.00
IUUC-Mmu-063956	Mus musculus	35.81	8.00e-88	315.00
IUUC-Mac-064521	Musa acuminata	33.58	2.00e-81	294.00
IUUC-Mpu-066716	Mustela putorius furo	34.86	1.00e-78	285.00
IUUC-Mlu-067459	Myotis lucifugus	35.35	4.00e-87	313.00
IUUC-Nfi-068245	Neosartorya fischeri	33.75	1.00e-76	278.00
IUUC-Ncr-068910	Neurospora crassa	35.65	1.00e-84	304.00
IUUC-Nle-070034	Nomascus leucogenys	33.14	3.00e-77	280.00
IUUC-Opr-070552	Ochotona princeps	30.94	1.00e-56	212.00
IUUC-Ont-071426	Oreochromis niloticus	32.26	3.00e-84	303.00
IUUC-Oan-073389	Ornithorhynchus anatinus	32.13	1.00e-53	201.00
IUUC-Ocu-074911	Oryctolagus cuniculus	35.11	1.00e-86	311.00
IUUC-Oba-075437	Oryza barthii	34.17	3.00e-72	263.00
IUUC-Obr-076684	Oryza brachyantha	33.59	3.00e-65	240.00
IUUC-Ogl-077170	Oryza glaberrima	34.17	3.00e-72	263.00
IUUC-Ogu-078844	Oryza glumaepatula	33.40	1.00e-65	241.00
IUUC-Oin-079105	Oryza indica	34.17	3.00e-72	264.00
IUUC-Olo-080943	Oryza longistaminata	30.75	3.00e-60	223.00
IUUC-Oni-082891	Oryza nivara	31.66	8.00e-67	245.00
IUUC-Opu-083457	Oryza punctata	34.36	1.00e-71	261.00
IUUC-Oru-084960	Oryza rufipogon	30.75	3.00e-60	223.00
IUUC-Osa-085358	Oryza sativa	34.36	2.00e-72	265.00
IUUC-Ola-086420	Oryzias latipes	29.70	1.00e-43	168.00
IUUC-Olu-087625	Ostreococcus lucimarinus	28.24	5.00e-47	179.00
IUUC-Oga-088810	Otolemur garnettii	34.67	3.00e-86	310.00
IUUC-Oar-089196	Ovis aries	35.80	3.00e-87	313.00
IUUC-Ptr-090617	Pan troglodytes	34.86	5.00e-86	309.00
IUUC-Pan-092761	Papio anubis	35.05	5.00e-87	312.00
IUUC-Psi-093191	Pelodiscus sinensis	33.98	2.00e-79	288.00
IUUC-Pma-094380	Petromyzon marinus	31.16	4.00e-66	243.00
IUUC-Pno-095084	Phaeosphaeria nodorum	31.96	4.00e-65	241.00
IUUC-Ppa-095875	Physcomitrella patens	31.93	3.00e-76	277.00
IUUC-Pfo-096467	Poecilia formosa	32.07	2.00e-82	298.00
IUUC-Pab-098255	Pongo abelii	37.12	4.00e-76	276.00
IUUC-Pop-099722	Populus trichocarpa	33.21	2.00e-82	297.00
IUUC-Pca-100807	Procavia capensis	41.71	2.00e-42	164.00
IUUC-Ppe-101280	Prunus persica	33.91	2.00e-80	291.00
IUUC-Pva-102333	Pteropus vampyrus	33.08	9.00e-78	282.00
IUUC-Pgr-103401	Puccinia graminis	31.27	3.00e-73	267.00
IUUC-Ptt-103889	Puccinia triticina	27.24	4.00e-55	207.00
IUUC-Pte-104355	Pyrenophora teres	35.60	3.00e-81	293.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	35.18	3.00e-80	290.00
IUUC-Rno-105810	Rattus norvegicus	35.05	2.00e-87	314.00
IUUC-Sce-106397	Saccharomyces cerevisiae	27.44	2.00e-35	141.00
IUUC-Sha-106770	Sarcophilus harrisii	40.96	1.00e-57	214.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	28.80	5.00e-70	256.00
IUUC-Spo-108276	Schizosaccharomyces pombe	35.84	5.00e-81	292.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	38.00	2.00e-80	291.00
IUUC-Smo-109213	Selaginella moellendorffii	33.01	2.00e-79	287.00
IUUC-Sit-110157	Setaria italica	33.53	5.00e-80	289.00
IUUC-Sly-111105	Solanum lycopersicum	32.15	8.00e-80	288.00
IUUC-Stu-112469	Solanum tuberosum	32.09	6.00e-80	289.00
IUUC-Sar-113083	Sorex araneus	42.48	9.00e-35	139.00
IUUC-Sbi-113813	Sorghum bicolor	33.52	2.00e-79	288.00
IUUC-Sre-115058	Sporisorium reilianum	35.47	1.00e-64	238.00
IUUC-Tgu-116772	Taeniopygia guttata	35.55	3.00e-82	297.00
IUUC-Tru-118686	Takifugu rubripes	32.83	2.00e-82	297.00
IUUC-Tsy-119111	Tarsius syrichta	35.53	3.00e-44	170.00
IUUC-Tni-120231	Tetraodon nigroviridis	29.36	6.00e-66	243.00
IUUC-Tca-121491	Theobroma cacao	33.59	9.00e-78	282.00
IUUC-Tre-122103	Trichoderma reesei	36.69	2.00e-92	330.00
IUUC-Tvi-122672	Trichoderma virens	37.93	2.00e-89	320.00
IUUC-Tae-125316	Triticum aestivum	35.26	7.00e-84	302.00
IUUC-Tur-126487	Triticum urartu	33.91	9.00e-79	285.00
IUUC-Tme-127097	Tuber melanosporum	32.36	3.00e-67	247.00
IUUC-Ttr-128465	Tursiops truncatus	33.14	4.00e-78	283.00
IUUC-Uma-129645	Ustilago maydis	35.47	3.00e-65	241.00
IUUC-Vda-129989	Verticillium dahliae	32.63	6.00e-66	242.00
IUUC-Vpa-130529	Vicugna pacos	34.10	3.00e-79	287.00
IUUC-Vvi-131059	Vitis vinifera	33.53	5.00e-82	296.00
IUUC-Xtr-132002	Xenopus tropicalis	34.48	2.00e-84	304.00
IUUC-Xma-133930	Xiphophorus maculatus	32.63	2.00e-82	297.00
IUUC-Zma-135895	Zea mays	33.14	3.00e-78	283.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence