iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Post-translational Modifications (PTMs)
CPLM	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.60e-07	30.7	20	66

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw..pglknssskefrCPlC 45
           C++C  +f+d p++l C H f+++Cl  +w  p  + s+  + +CP C
   Q: 20   CPLCGGPFED-PVLLACEHSFCRSCLaRCWgsPAAPGSEEATPSCPCC 66
           **********.999************9999**9999999*******99 PP

Organism

Rattus norvegicus

Functional Description
(View)

May play a role in prolonged long term-potentiation (LTP) maintenance.

Protein Sequence
(Fasta)

MEVPELGPGL VERLEQLATC PLCGGPFEDP VLLACEHSFC RSCLARCWGS PAAPGSEEAT 60
PSCPCCGQPC PRRSLRSNVR LAVEVRISRG LREKLAEPGA RTGRRRGGRI PTMGCLDPQG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTCCGCTC TGGGTAACCA AGGCAGCCCG GGAGAGGGGT AGATAGGGGG TGCAAAGTGA 60
ATGAGGGAGG CGCAGCGAGG GGCGTCGAGT CAGCACGCAG CGGGCGTGGT CCGCCACTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00097--zf-C3HC4

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0008270--F:zinc ion binding
GO:0048168--P:regulation of neuronal synaptic plasticity

KEGG

rno:171387

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-018750	Callithrix jacchus	81.82	1.00e-146	512.00
IUUC-Cfa-020026	Canis familiaris	80.28	3.00e-136	478.00
IUUC-Csa-024011	Chlorocebus sabaeus	81.82	5.00e-148	517.00
IUUC-Dor-030883	Dipodomys ordii	86.65	6.00e-163	566.00
IUUC-Ete-033195	Echinops telfairi	72.44	4.00e-108	384.00
IUUC-Eca-034051	Equus caballus	66.33	6.00e-85	307.00
IUUC-Hsa-045858	Homo sapiens	82.39	3.00e-149	521.00
IUUC-Itr-047886	Ictidomys tridecemlineatus	85.23	5.00e-161	560.00
IUUC-Laf-053446	Loxodonta africana	81.53	3.00e-130	457.00
IUUC-Mcc-055579	Macaca mulatta	79.89	3.00e-141	494.00
IUUC-Mmu-063921	Mus musculus	94.32	1.00e-170	592.00
IUUC-Nle-069017	Nomascus leucogenys	81.53	4.00e-147	514.00
IUUC-Oga-088846	Otolemur garnettii	83.19	1.00e-139	489.00
IUUC-Ptr-091464	Pan troglodytes	83.47	1.00e-46	179.00
IUUC-Pan-092055	Papio anubis	81.82	1.00e-147	516.00
IUUC-Pfo-096459	Poecilia formosa	28.49	2.00e-24	105.00
IUUC-Pab-098409	Pongo abelii	80.47	1.00e-95	342.00
IUUC-Pca-100434	Procavia capensis	73.50	3.00e-128	451.00
IUUC-Pva-102973	Pteropus vampyrus	80.40	7.00e-150	523.00
IUUC-Sha-106523	Sarcophilus harrisii	76.20	9.00e-135	473.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence