iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026838

Ensembl Protein ID

AAW41436

UniProt Accession

P0CS32; Q55ZC3; Q5KNN8; EIF3I_CRYNJ

Genbank Protein ID

AAW41436.1

Protein Name

Eukaryotic translation initiation factor 3 subunit I; Eukaryotic translation initiation factor 3 39 kDa subunit homolog

Genbank Nucleotide ID

AE017341

Gene Name

TIF34; CNA05850

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNA05850	AAW41436	AAW41436

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-21	73.5	56	94

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH++sv+ +a  s  ++l++G+ D+ +k+W+++tg +l 
   Q: 56   GHNGSVWTVAVdSQtRFLLTGGADNAMKLWEVKTGECLY 94
           8**********955599*******************986 PP

Organism

Cryptococcus neoformans

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MKPIILQGHE RSLNQIVFNS EGDLLFSASK DSVVNAWYTS NGERLGTYGG IKGGDGHNGS 60
VWTVAVDSQT RFLLTGGADN AMKLWEVKTG ECLYTWEFLT AVKRVAWNED DDMFLSITEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATAAAAAAA GCATAGCAGC AAAATGGTGA GCATATAAGA GGTCCCAAAA TGAAGTGGCC 60
AAGATGATGC TGACATTCAG TATAGAAACC TATCATTCTC CAAGGTCCGC TTTTATCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0022627--C:cytosolic small ribosomal subunit
GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0071540--C:eukaryotic translation initiation factor 3 complex, eIF3e
GO:0071541--C:eukaryotic translation initiation factor 3 complex, eIF3m
GO:0043614--C:multi-eIF complex
GO:0034399--C:nuclear periphery
GO:0003743--F:translation initiation factor activity
GO:0071470--P:cellular response to osmotic stress
GO:0002188--P:translation reinitiation

KEGG

cne:CNA05850

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	55.75	4.00e-36	143.00
IUUC-Aml-001321	Ailuropoda melanoleuca	49.39	1.00e-93	334.00
IUUC-Atr-002468	Amborella trichopoda	45.55	7.00e-51	191.00
IUUC-Apl-003841	Anas platyrhynchos	49.08	4.00e-95	338.00
IUUC-Aca-005123	Anolis carolinensis	48.01	4.00e-92	328.00
IUUC-Aly-005473	Arabidopsis lyrata	40.79	1.00e-76	278.00
IUUC-Ath-007094	Arabidopsis thaliana	40.79	6.00e-77	278.00
IUUC-Ago-008000	Ashbya gossypii	46.85	2.00e-89	320.00
IUUC-Acl-008098	Aspergillus clavatus	56.72	2.00e-107	380.00
IUUC-Afl-008494	Aspergillus flavus	56.40	1.00e-110	390.00
IUUC-Afu-009080	Aspergillus fumigatus	55.82	2.00e-107	380.00
IUUC-Ani-009230	Aspergillus nidulans	55.89	3.00e-107	379.00
IUUC-Aor-010114	Aspergillus oryzae	56.40	1.00e-110	390.00
IUUC-Ate-010285	Aspergillus terreus	56.80	1.00e-107	380.00
IUUC-Ame-011534	Astyanax mexicanus	47.88	3.00e-93	332.00
IUUC-Bgr-012121	Blumeria graminis	50.15	1.00e-96	344.00
IUUC-Bta-013143	Bos taurus	49.54	3.00e-94	336.00
IUUC-Bci-013950	Botrytis cinerea	55.18	8.00e-107	377.00
IUUC-Bdi-015019	Brachypodium distachyon	44.71	8.00e-79	285.00
IUUC-Bol-015709	Brassica oleracea	40.48	2.00e-74	271.00
IUUC-Bra-017760	Brassica rapa	40.48	9.00e-75	272.00
IUUC-Cel-018226	Caenorhabditis elegans	39.94	2.00e-73	266.00
IUUC-Cja-019741	Callithrix jacchus	49.54	1.00e-94	337.00
IUUC-Cfa-021204	Canis familiaris	49.08	2.00e-93	333.00
IUUC-Cpo-021661	Cavia porcellus	49.39	8.00e-94	334.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	40.66	1.00e-74	271.00
IUUC-Csa-024038	Chlorocebus sabaeus	49.54	1.00e-94	337.00
IUUC-Cin-025597	Ciona intestinalis	48.93	4.00e-92	328.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	51.83	5.00e-98	348.00
IUUC-Cme-027304	Cyanidioschyzon merolae	41.03	6.00e-69	252.00
IUUC-Dre-028567	Danio rerio	47.71	4.00e-92	329.00
IUUC-Dno-029171	Dasypus novemcinctus	49.39	2.00e-93	334.00
IUUC-Dor-030257	Dipodomys ordii	34.97	7.00e-30	122.00
IUUC-Dse-031191	Dothistroma septosporum	55.15	1.00e-105	374.00
IUUC-Dme-031879	Drosophila melanogaster	48.02	5.00e-92	328.00
IUUC-Ete-032336	Echinops telfairi	46.38	6.00e-53	198.00
IUUC-Eca-033259	Equus caballus	49.08	2.00e-93	333.00
IUUC-Eeu-035153	Erinaceus europaeus	45.52	4.00e-29	120.00
IUUC-Fca-036489	Felis catus	49.08	2.00e-93	333.00
IUUC-Fal-037485	Ficedula albicollis	48.47	2.00e-94	337.00
IUUC-Fox-037860	Fusarium oxysporum	53.35	1.00e-101	360.00
IUUC-Fso-038188	Fusarium solani	52.13	6.00e-98	348.00
IUUC-Gmo-039311	Gadus morhua	48.77	7.00e-94	335.00
IUUC-Ggr-040045	Gaeumannomyces graminis	53.15	2.00e-103	367.00
IUUC-Gga-040645	Gallus gallus	48.06	1.00e-93	334.00
IUUC-Gac-042086	Gasterosteus aculeatus	47.09	1.00e-90	323.00
IUUC-Gma-043246	Glycine max	42.55	4.00e-78	282.00
IUUC-Ggo-045578	Gorilla gorilla	49.54	1.00e-94	337.00
IUUC-Hsa-046734	Homo sapiens	49.54	1.00e-94	337.00
IUUC-Hvu-047553	Hordeum vulgare	44.11	8.00e-78	281.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	49.08	2.00e-93	333.00
IUUC-Kpa-049325	Komagataella pastoris	49.24	2.00e-94	337.00
IUUC-Lch-049620	Latimeria chalumnae	49.35	3.00e-86	309.00
IUUC-Lpe-051338	Leersia perrieri	42.77	7.00e-75	271.00
IUUC-Loc-052094	Lepisosteus oculatus	44.71	1.00e-79	288.00
IUUC-Lma-053047	Leptosphaeria maculans	54.41	2.00e-106	377.00
IUUC-Laf-053801	Loxodonta africana	49.06	1.00e-90	324.00
IUUC-Mcc-055498	Macaca mulatta	44.04	7.00e-75	271.00
IUUC-Meu-056729	Macropus eugenii	45.43	4.00e-82	295.00
IUUC-Mor-057025	Magnaporthe oryzae	51.52	3.00e-101	359.00
IUUC-Mpo-057511	Magnaporthe poae	54.27	2.00e-104	369.00
IUUC-Mtr-058051	Medicago truncatula	42.25	2.00e-77	280.00
IUUC-Mla-059061	Melampsora laricipopulina	54.71	4.00e-112	395.00
IUUC-Mga-059229	Meleagris gallopavo	48.48	1.00e-92	331.00
IUUC-Mvi-060399	Microbotryum violaceum	54.86	3.00e-115	405.00
IUUC-Mmr-060764	Microcebus murinus	49.54	1.00e-94	337.00
IUUC-Mdo-062088	Monodelphis domestica	48.62	3.00e-91	326.00
IUUC-Mmu-064304	Mus musculus	49.54	1.00e-94	337.00
IUUC-Mac-065520	Musa acuminata	43.52	7.00e-81	291.00
IUUC-Mpu-066340	Mustela putorius furo	49.08	2.00e-93	333.00
IUUC-Mlu-067111	Myotis lucifugus	49.69	3.00e-94	336.00
IUUC-Nfi-068478	Neosartorya fischeri	55.22	4.00e-106	375.00
IUUC-Ncr-068820	Neurospora crassa	50.91	3.00e-97	346.00
IUUC-Nle-069903	Nomascus leucogenys	49.39	5.00e-94	335.00
IUUC-Opr-070221	Ochotona princeps	48.32	2.00e-91	327.00
IUUC-Ont-071765	Oreochromis niloticus	47.40	6.00e-92	328.00
IUUC-Oan-073660	Ornithorhynchus anatinus	46.44	2.00e-78	283.00
IUUC-Ocu-074039	Oryctolagus cuniculus	49.39	7.00e-94	335.00
IUUC-Oba-075395	Oryza barthii	36.78	2.00e-60	223.00
IUUC-Obr-076334	Oryza brachyantha	41.34	3.00e-73	266.00
IUUC-Ogl-077751	Oryza glaberrima	43.16	5.00e-79	285.00
IUUC-Ogu-078207	Oryza glumaepatula	43.16	2.00e-79	287.00
IUUC-Oin-079878	Oryza indica	43.16	2.00e-79	286.00
IUUC-Olo-080677	Oryza longistaminata	37.60	3.00e-72	263.00
IUUC-Oni-082411	Oryza nivara	36.17	1.00e-58	218.00
IUUC-Opu-083136	Oryza punctata	43.16	4.00e-79	285.00
IUUC-Oru-084916	Oryza rufipogon	41.72	1.00e-76	277.00
IUUC-Osa-085454	Oryza sativa	43.16	2.00e-79	286.00
IUUC-Ola-087053	Oryzias latipes	48.01	6.00e-94	335.00
IUUC-Olu-087602	Ostreococcus lucimarinus	47.71	2.00e-89	320.00
IUUC-Oga-088154	Otolemur garnettii	49.39	5.00e-94	335.00
IUUC-Oar-089915	Ovis aries	49.39	2.00e-93	333.00
IUUC-Ptr-091124	Pan troglodytes	41.67	9.00e-69	251.00
IUUC-Pan-092035	Papio anubis	49.54	1.00e-94	337.00
IUUC-Psi-094096	Pelodiscus sinensis	48.57	4.00e-58	215.00
IUUC-Pno-094988	Phaeosphaeria nodorum	48.32	2.00e-89	320.00
IUUC-Ppa-095536	Physcomitrella patens	45.59	1.00e-82	297.00
IUUC-Pfo-096101	Poecilia formosa	46.79	3.00e-91	326.00
IUUC-Pab-097726	Pongo abelii	49.54	1.00e-94	337.00
IUUC-Pop-099617	Populus trichocarpa	43.47	5.00e-79	285.00
IUUC-Pca-101014	Procavia capensis	49.85	7.00e-95	338.00
IUUC-Ppe-101320	Prunus persica	42.25	2.00e-76	276.00
IUUC-Pva-102789	Pteropus vampyrus	44.65	1.00e-79	287.00
IUUC-Pgr-103479	Puccinia graminis	54.84	4.00e-113	399.00
IUUC-Ptt-103981	Puccinia triticina	55.13	3.00e-114	402.00
IUUC-Pte-104278	Pyrenophora teres	53.50	3.00e-103	366.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	53.50	3.00e-103	366.00
IUUC-Rno-105867	Rattus norvegicus	45.27	3.00e-76	276.00
IUUC-Sce-106251	Saccharomyces cerevisiae	50.30	8.00e-96	341.00
IUUC-Sha-107039	Sarcophilus harrisii	47.51	1.00e-91	327.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	51.06	1.00e-104	370.00
IUUC-Spo-108314	Schizosaccharomyces pombe	51.52	4.00e-105	372.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	55.18	1.00e-106	377.00
IUUC-Smo-108728	Selaginella moellendorffii	43.64	1.00e-80	291.00
IUUC-Sit-110801	Setaria italica	42.90	6.00e-78	282.00
IUUC-Sly-111326	Solanum lycopersicum	43.37	2.00e-80	290.00
IUUC-Stu-112458	Solanum tuberosum	43.47	1.00e-79	288.00
IUUC-Sbi-114063	Sorghum bicolor	42.90	1.00e-77	281.00
IUUC-Sre-115096	Sporisorium reilianum	54.89	4.00e-107	379.00
IUUC-Ssc-116080	Sus scrofa	49.54	2.00e-94	336.00
IUUC-Tgu-116988	Taeniopygia guttata	48.16	6.00e-94	335.00
IUUC-Tru-118766	Takifugu rubripes	48.93	2.00e-94	336.00
IUUC-Tni-120197	Tetraodon nigroviridis	48.62	8.00e-94	334.00
IUUC-Tca-121316	Theobroma cacao	42.25	3.00e-77	280.00
IUUC-Tre-122097	Trichoderma reesei	52.44	2.00e-100	357.00
IUUC-Tvi-122442	Trichoderma virens	52.44	3.00e-100	356.00
IUUC-Tae-125800	Triticum aestivum	43.50	6.00e-78	282.00
IUUC-Tur-126334	Triticum urartu	36.86	3.00e-59	219.00
IUUC-Tme-127038	Tuber melanosporum	55.79	8.00e-110	387.00
IUUC-Ttr-128659	Tursiops truncatus	46.18	1.00e-77	281.00
IUUC-Uma-129464	Ustilago maydis	55.46	4.00e-108	382.00
IUUC-Vda-129841	Verticillium dahliae	54.27	7.00e-104	368.00
IUUC-Vvi-131076	Vitis vinifera	41.57	2.00e-77	280.00
IUUC-Xtr-132395	Xenopus tropicalis	49.24	2.00e-93	333.00
IUUC-Xma-133383	Xiphophorus maculatus	46.79	4.00e-91	325.00
IUUC-Yli-134586	Yarrowia lipolytica	46.97	1.00e-85	307.00
IUUC-Zma-135667	Zea mays	43.50	1.00e-78	284.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence