iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-117651

UUCD1 version

UUC-TaR-01152

Ensembl Protein ID

ENSTRUP00000000605.1

UniProt Accession

H2RKE2; H2RKE2_TAKRU

Protein Name

Uncharacterized protein

Gene Name

usp48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000000276.1	ENSTRUT00000000608.1	ENSTRUP00000000605.1
ENSTRUG00000000276.1	ENSTRUT00000000609.1	ENSTRUP00000000606.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.80e-74	251.6	89	420
ULD/UDP/UBQ/UBQ_Other	7.30e-08	33.4	983	1045

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.......kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeae 82
           +Gl+Nlg+tCY+N  LQ+ ++  elr+ l e       +++     ++   + ++++++lq lf+ l++s++k+++p+ l+kal+    
   Q: 89   VGLTNLGATCYVNTFLQVWFHNLELRRSLYEcnssraqEHNTGSGTSETHYEPQSICEHLQYLFALLQNSNRKYIDPSGLVKALG---- 173
           6******************************55555544444444444477788******************************9.... PP
   S: 83   efsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfld 171
            +++ +qqDaqEf + +l+ le++l                       +++k+++ +++i++ F gq++  ++c++c+++s   + f++
   Q: 174  -LDTGQQQDAQEFSKLFLSLLENTL-----------------------SKQKNTSLQNVIQRQFCGQFSYVTVCNQCGRSSALPSRFYE 238
           .78899*******************.......................46789999********************************* PP
   S: 172  lslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           l+l+++g++     +l +c  +f kee+l+gen+y+ce+c++kq a+++++l++lP++L l+L+Rf f++++++++k+n+ ++fp++Ld
   Q: 239  LELNIQGHK-----NLMECVTEFLKEEKLDGENRYFCESCQSKQSATRRIRLHSLPPTLNLQLMRFVFDRQTGHKKKLNTFISFPEQLD 322
           *********.....9************************************************************************** PP
   S: 261  lspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg.................... 327
           + pf++ ++++   +  YeL+av++H G s+ sGHY+a+vk+ + + W++f+D+++++++ ++ +   +                    
   Q: 323  MGPFLEGKQDQ---HSVYELSAVLIHRGiSAYSGHYIAHVKDAHTGdWYKFNDEEIEKMEGKKLQLGLEediaetvksqtrkpkctkgs 408
           ******96544...89**************************76666************999999966699****************** PP
   S: 328  ...staYvlfYk 336
              ++aY+l+Yk
   Q: 409  hcsRNAYMLVYK 420
           ***********8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 13   ltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
             l v+   t +eLK +i +++++ p +q+L ++Gk L +d  tL+++g+ ++s i+l  +++
   Q: 983  KALIVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKGLtDDSATLGSLGVVPESIICLKADEP 1045
           556689999*********************************************999988876 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MAPRLQLEKA AWRWVETVKP EDITQEHINL AYRINLTACK RGTCRRNCRG NPNCLVAIGE 60
QAWLGEIDEN TFHNIDDPNS ERRDKNTFVG LTNLGATCYV NTFLQVWFHN LELRRSLYEC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGACCGTGCA GAGTAAAGGT TTTCCTGATA AATGCTGTTA AGGGCGCTAA ATCTAAAACA 60
ACCCGTGAAT AAAATGTGAA AAATACACAA GTGTTTTTGT AAAATAGCTG CACGCATGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	34.08	5.00e-80	292.00
IUUC-Aml-001357	Ailuropoda melanoleuca	65.71	0.00e+00	1402.00
IUUC-Atr-002976	Amborella trichopoda	28.96	3.00e-83	303.00
IUUC-Apl-003773	Anas platyrhynchos	65.56	0.00e+00	1275.00
IUUC-Aca-004466	Anolis carolinensis	70.51	0.00e+00	763.00
IUUC-Aly-006249	Arabidopsis lyrata	27.07	1.00e-70	261.00
IUUC-Ath-006700	Arabidopsis thaliana	26.95	2.00e-83	304.00
IUUC-Ame-011554	Astyanax mexicanus	75.00	0.00e+00	1628.00
IUUC-Bta-012573	Bos taurus	65.65	0.00e+00	1408.00
IUUC-Bdi-014149	Brachypodium distachyon	32.92	2.00e-84	307.00
IUUC-Bol-016289	Brassica oleracea	29.16	2.00e-80	294.00
IUUC-Bra-017205	Brassica rapa	29.32	4.00e-75	276.00
IUUC-Cel-018662	Caenorhabditis elegans	30.38	2.00e-30	128.00
IUUC-Cja-019991	Callithrix jacchus	65.20	0.00e+00	1408.00
IUUC-Cfa-020294	Canis familiaris	65.86	0.00e+00	1427.00
IUUC-Cpo-021706	Cavia porcellus	65.37	0.00e+00	1347.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	35.71	4.00e-42	168.00
IUUC-Csa-023931	Chlorocebus sabaeus	66.33	0.00e+00	1424.00
IUUC-Cho-024566	Choloepus hoffmanni	61.02	7.00e-97	348.00
IUUC-Cin-025307	Ciona intestinalis	48.49	7.00e-79	286.00
IUUC-Csv-026006	Ciona savignyi	35.12	6.00e-151	528.00
IUUC-Cne-027065	Cryptococcus neoformans	27.59	9.00e-70	258.00
IUUC-Dre-027624	Danio rerio	73.86	0.00e+00	1634.00
IUUC-Dno-029633	Dasypus novemcinctus	67.26	0.00e+00	917.00
IUUC-Dor-030809	Dipodomys ordii	75.76	1.00e-153	537.00
IUUC-Ete-032818	Echinops telfairi	68.90	0.00e+00	722.00
IUUC-Eca-033692	Equus caballus	65.95	0.00e+00	1416.00
IUUC-Eeu-035185	Erinaceus europaeus	46.15	1.00e-137	484.00
IUUC-Fca-035676	Felis catus	65.52	0.00e+00	1419.00
IUUC-Fal-036913	Ficedula albicollis	65.86	0.00e+00	1419.00
IUUC-Gmo-038532	Gadus morhua	78.70	0.00e+00	1730.00
IUUC-Gga-041041	Gallus gallus	66.98	0.00e+00	1433.00
IUUC-Gac-042570	Gasterosteus aculeatus	84.35	0.00e+00	1835.00
IUUC-Gma-044136	Glycine max	29.08	2.00e-84	307.00
IUUC-Ggo-045367	Gorilla gorilla	63.80	0.00e+00	1334.00
IUUC-Hsa-046019	Homo sapiens	66.14	0.00e+00	1422.00
IUUC-Hvu-047303	Hordeum vulgare	34.92	1.00e-63	237.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	66.05	0.00e+00	1417.00
IUUC-Lch-049989	Latimeria chalumnae	68.00	0.00e+00	1479.00
IUUC-Lpe-051612	Leersia perrieri	31.27	2.00e-78	287.00
IUUC-Loc-052756	Lepisosteus oculatus	71.90	0.00e+00	1592.00
IUUC-Laf-054043	Loxodonta africana	66.02	0.00e+00	1423.00
IUUC-Mcc-054986	Macaca mulatta	65.33	0.00e+00	1407.00
IUUC-Meu-056228	Macropus eugenii	76.66	4.00e-160	558.00
IUUC-Mtr-058610	Medicago truncatula	29.32	1.00e-77	284.00
IUUC-Mga-059896	Meleagris gallopavo	65.87	0.00e+00	1339.00
IUUC-Mvi-060269	Microbotryum violaceum	38.86	4.00e-67	250.00
IUUC-Mmr-060887	Microcebus murinus	65.86	0.00e+00	1417.00
IUUC-Mdo-062506	Monodelphis domestica	66.33	0.00e+00	1426.00
IUUC-Mmu-063642	Mus musculus	66.05	0.00e+00	1424.00
IUUC-Mac-064896	Musa acuminata	31.15	4.00e-74	273.00
IUUC-Mpu-066194	Mustela putorius furo	65.70	0.00e+00	1421.00
IUUC-Mlu-067233	Myotis lucifugus	65.44	0.00e+00	1410.00
IUUC-Nle-069052	Nomascus leucogenys	65.51	0.00e+00	1408.00
IUUC-Opr-070890	Ochotona princeps	70.14	0.00e+00	906.00
IUUC-Ont-071450	Oreochromis niloticus	77.45	0.00e+00	1705.00
IUUC-Oan-073252	Ornithorhynchus anatinus	58.16	0.00e+00	687.00
IUUC-Ocu-073796	Oryctolagus cuniculus	65.40	0.00e+00	1207.00
IUUC-Oba-075563	Oryza barthii	30.10	3.00e-79	290.00
IUUC-Obr-076394	Oryza brachyantha	32.41	2.00e-80	294.00
IUUC-Ogl-077339	Oryza glaberrima	39.25	1.00e-40	159.00
IUUC-Ogu-079007	Oryza glumaepatula	34.02	6.00e-72	266.00
IUUC-Oin-079997	Oryza indica	30.10	2.00e-79	291.00
IUUC-Olo-080364	Oryza longistaminata	30.10	3.00e-79	290.00
IUUC-Ome-081165	Oryza meridionalis	34.36	2.00e-73	271.00
IUUC-Oni-083026	Oryza nivara	30.10	2.00e-79	290.00
IUUC-Opu-083284	Oryza punctata	34.85	1.00e-74	275.00
IUUC-Oru-084797	Oryza rufipogon	30.34	2.00e-79	290.00
IUUC-Osa-086221	Oryza sativa	39.25	1.00e-40	159.00
IUUC-Ola-086568	Oryzias latipes	81.43	0.00e+00	1790.00
IUUC-Oga-088687	Otolemur garnettii	65.17	0.00e+00	1406.00
IUUC-Oar-090345	Ovis aries	65.48	0.00e+00	1341.00
IUUC-Ptr-090734	Pan troglodytes	66.23	0.00e+00	1425.00
IUUC-Pan-091704	Papio anubis	64.24	0.00e+00	1351.00
IUUC-Psi-092937	Pelodiscus sinensis	64.44	0.00e+00	1203.00
IUUC-Ppa-095808	Physcomitrella patens	28.54	2.00e-75	277.00
IUUC-Pab-098129	Pongo abelii	66.23	0.00e+00	1424.00
IUUC-Pop-099494	Populus trichocarpa	28.95	1.00e-82	301.00
IUUC-Pca-100647	Procavia capensis	75.53	1.00e-152	534.00
IUUC-Ppe-102091	Prunus persica	32.87	5.00e-82	299.00
IUUC-Pva-102719	Pteropus vampyrus	65.36	0.00e+00	1407.00
IUUC-Rno-105363	Rattus norvegicus	65.61	0.00e+00	1423.00
IUUC-Sha-107620	Sarcophilus harrisii	63.57	0.00e+00	1306.00
IUUC-Smo-109487	Selaginella moellendorffii	26.29	4.00e-76	280.00
IUUC-Sit-110683	Setaria italica	31.08	6.00e-82	299.00
IUUC-Sly-111377	Solanum lycopersicum	27.40	4.00e-76	279.00
IUUC-Stu-111969	Solanum tuberosum	30.43	2.00e-66	246.00
IUUC-Sar-113099	Sorex araneus	66.10	0.00e+00	1205.00
IUUC-Sbi-113833	Sorghum bicolor	44.12	2.00e-59	222.00
IUUC-Ssc-115279	Sus scrofa	57.32	0.00e+00	858.00
IUUC-Tgu-117519	Taeniopygia guttata	63.05	0.00e+00	1274.00
IUUC-Tsy-119201	Tarsius syrichta	63.79	0.00e+00	1261.00
IUUC-Tni-120840	Tetraodon nigroviridis	91.61	0.00e+00	1991.00
IUUC-Tca-121674	Theobroma cacao	27.89	2.00e-86	313.00
IUUC-Tae-125247	Triticum aestivum	34.08	8.00e-80	292.00
IUUC-Tur-126599	Triticum urartu	34.08	1.00e-78	288.00
IUUC-Tbe-127782	Tupaia belangeri	58.51	0.00e+00	1194.00
IUUC-Ttr-128312	Tursiops truncatus	64.65	0.00e+00	1387.00
IUUC-Vpa-130348	Vicugna pacos	65.19	0.00e+00	1336.00
IUUC-Vvi-131353	Vitis vinifera	31.23	8.00e-82	298.00
IUUC-Xtr-132172	Xenopus tropicalis	59.11	0.00e+00	1123.00
IUUC-Xma-133263	Xiphophorus maculatus	80.15	0.00e+00	1724.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence