iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074303

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AAGW02054189

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000016766.3	ENSOCUT00000016766.3	ENSOCUP00000014412.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.90e-100	336.6	281	601

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 1    mnsqvkewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktif 89
           m++++ ew+ +esdPg+ft+l++ fg+++  qvee++sL+pen++++ +pv+gl++lFk+++ +e +          +vv+++ ++tif
   Q: 281  MTGNAGEWCLMESDPGVFTELIKGFGCRGA-QVEEIWSLEPENFEKL-KPVHGLIFLFKWQPGEEPAG---------SVVQDSRLDTIF 358
           788999************************.****************.********************.........899********* PP
   S: 90   fakqvigNsCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeaf 178
           fakqvi+N+Cat+A++svllnc+++ ++lG+tls++ke+++++++ +k+lal+n++v++++hns+ar+++++ + +++++    +++af
   Q: 359  FAKQVINNACATQAIVSVLLNCTHQDVHLGETLSEFKEFSQSFDAAMKGLALSNSDVIRQVHNSFARQQMFEFDAKTSAK----EEDAF 443
           ****************************************************************************9887....79*** PP
   S: 179  hfvsyvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkid........ 259
           hfvsyv++ngrlyeldgl++ P+dlg+ ++++++ ++++ v+   +ri++++++eirfnl+aiv+dr++i+++++  l+ +        
   Q: 444  HFVSYVPVNGRLYELDGLREGPIDLGA-CNQDDWISAVRPVI--EKRIQKYSEGEIRFNLMAIVSDRKMIYEQKIAELQRQlaeeepmd 529
           **************************9.78999*********..******************************976665567777777 PP
   S: 260  .keLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveetisevrefg 333
             +  ++l++i+se++k+++ +++e++k k++ki++irR++ny  fi++++k+la++++l  lve+    + +++
   Q: 530  tDQGSNMLSAIQSEVAKNQMLIEEEVQKLKRYKIENIRRKHNYLPFIMELLKTLAEHQQLIPLVEKA---KEKQN 601
           755568**********************************************************993...33344 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MHILRAAENF LLEGSWRQAF CTGPRRPGAG PAGTALLGAH SLGAARDDAP SPRLRLAGRR 60
PTDPASESRA TPVRAAAAGG AGGGRTRARA AAPSDAALRR RRGRTARGVS ARRAASGHRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCTCCCCG GGGTGGGCGG GCGGCAGGGC CCACGCACCT GTGCCGTCTC GCACCTGGTC 60
GTCCAGGGCA TCCTCCGTCT CCCCGGGGTG GGTGGGCGGC AGGCCCCACA CACCTGTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR033837--UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0031011--C:Ino80 complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	46.99	8.00e-84	303.00
IUUC-Aml-001866	Ailuropoda melanoleuca	99.68	0.00e+00	660.00
IUUC-Atr-002966	Amborella trichopoda	46.20	4.00e-81	295.00
IUUC-Apl-003306	Anas platyrhynchos	86.31	3.00e-179	620.00
IUUC-Aca-004763	Anolis carolinensis	95.82	0.00e+00	629.00
IUUC-Aly-005581	Arabidopsis lyrata	48.48	4.00e-79	288.00
IUUC-Ath-007283	Arabidopsis thaliana	48.48	7.00e-82	296.00
IUUC-Ago-007999	Ashbya gossypii	33.33	2.00e-32	132.00
IUUC-Acl-008231	Aspergillus clavatus	42.92	3.00e-51	195.00
IUUC-Afl-008557	Aspergillus flavus	37.58	2.00e-53	202.00
IUUC-Afu-008988	Aspergillus fumigatus	44.77	7.00e-54	204.00
IUUC-Ani-009420	Aspergillus nidulans	37.00	2.00e-51	196.00
IUUC-Ang-009859	Aspergillus niger	40.41	1.00e-48	186.00
IUUC-Aor-010145	Aspergillus oryzae	37.58	2.00e-53	202.00
IUUC-Ate-010347	Aspergillus terreus	41.73	4.00e-52	198.00
IUUC-Ame-010791	Astyanax mexicanus	90.27	0.00e+00	635.00
IUUC-Bgr-012298	Blumeria graminis	37.50	1.00e-48	186.00
IUUC-Bta-013251	Bos taurus	99.36	0.00e+00	650.00
IUUC-Bci-013786	Botrytis cinerea	37.76	7.00e-57	214.00
IUUC-Bdi-014132	Brachypodium distachyon	48.92	3.00e-81	294.00
IUUC-Bol-015611	Brassica oleracea	49.70	4.00e-84	304.00
IUUC-Bra-017769	Brassica rapa	49.70	6.00e-84	303.00
IUUC-Cel-018604	Caenorhabditis elegans	47.13	3.00e-82	298.00
IUUC-Cja-019768	Callithrix jacchus	89.80	0.00e+00	647.00
IUUC-Cfa-020207	Canis familiaris	99.68	0.00e+00	660.00
IUUC-Cpo-021925	Cavia porcellus	95.53	0.00e+00	626.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	44.91	8.00e-73	266.00
IUUC-Csa-023958	Chlorocebus sabaeus	93.48	0.00e+00	656.00
IUUC-Cho-024928	Choloepus hoffmanni	100.00	8.00e-43	167.00
IUUC-Cin-025771	Ciona intestinalis	54.35	7.00e-100	356.00
IUUC-Csv-026149	Ciona savignyi	58.04	3.00e-103	368.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	37.50	2.00e-50	192.00
IUUC-Cne-026955	Cryptococcus neoformans	38.44	4.00e-54	204.00
IUUC-Cme-027104	Cyanidioschyzon merolae	32.79	1.00e-47	183.00
IUUC-Dre-027409	Danio rerio	89.36	2.00e-180	624.00
IUUC-Dno-028921	Dasypus novemcinctus	99.04	0.00e+00	657.00
IUUC-Dse-031170	Dothistroma septosporum	39.62	7.00e-58	217.00
IUUC-Dme-031677	Drosophila melanogaster	59.46	4.00e-115	407.00
IUUC-Ete-032707	Echinops telfairi	68.69	9.00e-124	436.00
IUUC-Eca-033776	Equus caballus	99.31	1.00e-174	605.00
IUUC-Eeu-035305	Erinaceus europaeus	79.59	2.00e-88	318.00
IUUC-Fca-035846	Felis catus	91.19	0.00e+00	655.00
IUUC-Fal-037597	Ficedula albicollis	96.18	4.00e-161	560.00
IUUC-Fox-037670	Fusarium oxysporum	50.22	7.00e-55	207.00
IUUC-Fso-038243	Fusarium solani	50.22	3.00e-54	205.00
IUUC-Gmo-038499	Gadus morhua	84.35	6.00e-163	566.00
IUUC-Ggr-039975	Gaeumannomyces graminis	41.06	2.00e-47	182.00
IUUC-Gga-040904	Gallus gallus	95.40	0.00e+00	654.00
IUUC-Gac-042058	Gasterosteus aculeatus	89.14	1.00e-172	598.00
IUUC-Gma-043030	Glycine max	48.96	6.00e-85	306.00
IUUC-Ggo-044699	Gorilla gorilla	93.16	5.00e-172	596.00
IUUC-Hsa-046227	Homo sapiens	99.04	0.00e+00	657.00
IUUC-Hvu-047359	Hordeum vulgare	46.99	3.00e-82	298.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	90.40	0.00e+00	654.00
IUUC-Lch-049829	Latimeria chalumnae	92.97	1.00e-177	614.00
IUUC-Lpe-050899	Leersia perrieri	48.26	2.00e-77	282.00
IUUC-Loc-052264	Lepisosteus oculatus	91.08	2.00e-175	608.00
IUUC-Lma-053110	Leptosphaeria maculans	38.41	3.00e-48	186.00
IUUC-Laf-053639	Loxodonta africana	99.68	0.00e+00	660.00
IUUC-Mcc-055506	Macaca mulatta	93.48	0.00e+00	656.00
IUUC-Mor-057001	Magnaporthe oryzae	45.38	2.00e-54	205.00
IUUC-Mpo-057608	Magnaporthe poae	39.13	3.00e-32	131.00
IUUC-Mtr-057731	Medicago truncatula	47.77	9.00e-85	306.00
IUUC-Mla-059016	Melampsora laricipopulina	42.93	2.00e-42	165.00
IUUC-Mga-060178	Meleagris gallopavo	95.72	5.00e-176	609.00
IUUC-Mvi-060353	Microbotryum violaceum	38.44	3.00e-53	202.00
IUUC-Mmr-060738	Microcebus murinus	99.04	0.00e+00	658.00
IUUC-Mdo-062266	Monodelphis domestica	98.04	1.00e-121	428.00
IUUC-Mmu-063619	Mus musculus	96.81	0.00e+00	640.00
IUUC-Mac-065301	Musa acuminata	50.16	3.00e-88	318.00
IUUC-Mpu-066058	Mustela putorius furo	100.00	0.00e+00	662.00
IUUC-Mlu-067292	Myotis lucifugus	98.08	0.00e+00	641.00
IUUC-Nfi-068275	Neosartorya fischeri	37.30	3.00e-54	204.00
IUUC-Ncr-068713	Neurospora crassa	38.92	4.00e-57	214.00
IUUC-Nle-069013	Nomascus leucogenys	93.20	0.00e+00	669.00
IUUC-Opr-070628	Ochotona princeps	86.25	1.00e-175	608.00
IUUC-Ont-072688	Oreochromis niloticus	89.84	1.00e-172	598.00
IUUC-Oan-073004	Ornithorhynchus anatinus	97.94	2.00e-143	501.00
IUUC-Oba-075002	Oryza barthii	49.54	7.00e-82	296.00
IUUC-Obr-076392	Oryza brachyantha	49.84	2.00e-79	288.00
IUUC-Ogl-077271	Oryza glaberrima	49.54	7.00e-82	296.00
IUUC-Ogu-078493	Oryza glumaepatula	49.54	2.00e-82	299.00
IUUC-Oin-080084	Oryza indica	49.54	2.00e-82	299.00
IUUC-Olo-080803	Oryza longistaminata	49.23	4.00e-82	297.00
IUUC-Ome-081146	Oryza meridionalis	48.61	6.00e-81	293.00
IUUC-Oni-082146	Oryza nivara	49.54	2.00e-82	299.00
IUUC-Opu-083633	Oryza punctata	48.90	3.00e-78	285.00
IUUC-Oru-084789	Oryza rufipogon	49.54	2.00e-82	299.00
IUUC-Osa-086196	Oryza sativa	49.54	2.00e-82	299.00
IUUC-Ola-087126	Oryzias latipes	89.78	3.00e-169	587.00
IUUC-Olu-087665	Ostreococcus lucimarinus	41.67	6.00e-68	250.00
IUUC-Oga-089140	Otolemur garnettii	90.59	0.00e+00	635.00
IUUC-Oar-090296	Ovis aries	99.04	0.00e+00	654.00
IUUC-Ptr-090566	Pan troglodytes	99.04	0.00e+00	657.00
IUUC-Pan-092052	Papio anubis	93.48	0.00e+00	655.00
IUUC-Psi-093723	Pelodiscus sinensis	95.83	5.00e-168	583.00
IUUC-Pma-094568	Petromyzon marinus	61.11	3.00e-105	374.00
IUUC-Pno-095120	Phaeosphaeria nodorum	45.22	2.00e-49	189.00
IUUC-Ppa-095761	Physcomitrella patens	47.66	7.00e-84	303.00
IUUC-Pfo-096210	Poecilia formosa	89.14	1.00e-172	598.00
IUUC-Pab-098463	Pongo abelii	94.02	0.00e+00	677.00
IUUC-Pop-099423	Populus trichocarpa	48.96	1.00e-84	305.00
IUUC-Pca-100108	Procavia capensis	96.79	3.00e-144	504.00
IUUC-Ppe-101176	Prunus persica	50.90	1.00e-85	309.00
IUUC-Pva-102629	Pteropus vampyrus	95.59	1.00e-154	538.00
IUUC-Pgr-103419	Puccinia graminis	40.55	9.00e-57	213.00
IUUC-Pte-104207	Pyrenophora teres	44.38	5.00e-33	133.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	39.22	1.00e-55	209.00
IUUC-Rno-105579	Rattus norvegicus	87.00	2.00e-164	571.00
IUUC-Sha-106894	Sarcophilus harrisii	94.57	1.00e-157	548.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	38.54	8.00e-59	220.00
IUUC-Spo-108371	Schizosaccharomyces pombe	41.86	3.00e-59	221.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	38.69	2.00e-46	179.00
IUUC-Smo-109396	Selaginella moellendorffii	51.08	9.00e-88	316.00
IUUC-Sit-110630	Setaria italica	49.69	1.00e-85	309.00
IUUC-Sly-110972	Solanum lycopersicum	50.16	2.00e-80	291.00
IUUC-Stu-112185	Solanum tuberosum	49.40	1.00e-88	319.00
IUUC-Sar-113294	Sorex araneus	81.32	3.00e-168	584.00
IUUC-Sbi-113951	Sorghum bicolor	50.00	3.00e-86	311.00
IUUC-Ssc-115501	Sus scrofa	98.65	9.00e-179	619.00
IUUC-Tgu-117152	Taeniopygia guttata	95.83	4.00e-161	560.00
IUUC-Tru-118388	Takifugu rubripes	88.82	2.00e-172	598.00
IUUC-Tsy-119109	Tarsius syrichta	99.07	0.00e+00	676.00
IUUC-Tni-120048	Tetraodon nigroviridis	88.82	5.00e-173	599.00
IUUC-Tca-121750	Theobroma cacao	48.82	4.00e-88	317.00
IUUC-Tre-122130	Trichoderma reesei	39.33	6.00e-55	207.00
IUUC-Tvi-122284	Trichoderma virens	39.53	4.00e-52	198.00
IUUC-Tae-124082	Triticum aestivum	47.59	8.00e-83	300.00
IUUC-Tur-126366	Triticum urartu	43.12	1.00e-66	246.00
IUUC-Tme-127187	Tuber melanosporum	41.45	1.00e-57	216.00
IUUC-Tbe-127619	Tupaia belangeri	90.24	5.00e-147	513.00
IUUC-Ttr-128867	Tursiops truncatus	88.16	4.00e-125	440.00
IUUC-Vda-129912	Verticillium dahliae	37.04	2.00e-51	196.00
IUUC-Vpa-130552	Vicugna pacos	100.00	6.00e-127	446.00
IUUC-Vvi-130881	Vitis vinifera	51.20	7.00e-85	306.00
IUUC-Xtr-131934	Xenopus tropicalis	86.02	2.00e-175	607.00
IUUC-Xma-133312	Xiphophorus maculatus	89.14	1.00e-172	598.00
IUUC-Yli-134487	Yarrowia lipolytica	39.74	3.00e-48	184.00
IUUC-Zma-135462	Zea mays	43.69	1.00e-71	262.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence