iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-017226

Ensembl Protein ID

Bra032492.1-P

UniProt Accession

M4EUL0; M4EUL0_BRARP

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra032492	Bra032492.1	Bra032492.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-81	274.8	196	875

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqqDaqEf 95
           Gl NlgNtC++NS++Q L+++ +lr+ +l+    +++     +   +l++sl+klf+e+    + k++v+pr+++++++++a++f+gy+q+D++E+
   Q: 196  GLVNLGNTCFFNSIMQNLLSLDQLRCHFLK---DDVS-----GVGLPLASSLRKLFAEMKpeAGLKSVVNPRAFFATFCAKAPQFRGYDQHDSHEL 283
           9*****************************...4444.....34579************99999******************************** PP
   S: 96   laflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke...... 185
           l++lld l++e +      + +        +    ++++k  + +l++ +F+g+++s + c ec+++s+ +epfldlslpvp k++  k+      
   Q: 284  LRCLLDLLSTEESA-----WRKR-------RGGVCDDDEKATSATLVESVFGGETSSIVSCIECGHSSKIYEPFLDLSLPVPFKKTPPKKqqalsr 367
           ***********922.....2222.......33346678999999**************************************99977666999*** PP
   S: 186  ................................................................................................ 185
                                                                                                           
   Q: 368  akkgklppkrvsknvskvskvskvvlptkamsepsspgkavvatadsdngavsetpsvitldnketsesvaqsdtvfdsfwldviapetfgdetnl 463
           ************************************************************************************************ PP
   S: 186  ................................................................................................ 185
                                                                                                           
   Q: 464  dmedsvsdktptpeantsvslsdqtsegnaerliqdsdefakadekdvqatqsdectaasaisaeinqdscigldpglgessssvnpwdeeevplm 559
           ************************************************************************************************ PP
   S: 186  ............................................................................................slqd 189
                                                                                                       s++ 
   Q: 560  vadsqvlympykenisynegeassssfvsgdhqepdnndfvglgglfdepevtegpvfgppckpeassgavgftafssesdpeeiddsdspvSVER 655
           ************************************************************************************************ PP
   S: 190  cLesftkeeelegenkyycekck...............................................................kkqeaekklk 222
           cL++ftk+e l ++n+++ce+c                                                                 k++a+k++ 
   Q: 656  CLAHFTKPEILSDDNAWNCENCSknlklqrlrekrkstsngwvsenedgvsgetdvkqdpsdsgreamssndsesegeedskkviiVKRDATKRVL 751
           ***********************8888888888888888888888888888888888888888888888888888888777777777777****** PP
   S: 223  lkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.............ekgk 305
           l+k+P+vL++hLkRfs + + ++ +k+n +v f++ +dl++++ +++++++ +  Y+L + v HsG++++GHYvayv+              +  +
   Q: 752  LNKVPPVLTIHLKRFSQDLR-GRLSKLNGHVAFKEVIDLRHYMDTRCSGED-PPVYRLAGLVEHSGTMRGGHYVAYVRGggggkkvkesgasS--S 843
           ***************98887.8889********************999985.***************************88887776655541..1 PP
   S: 306  ...WllfdDskVtevkeeevleetgstaYvlfYkr 337
              W++++D +V++v+ ++vl    s+aY+lfY+r
   Q: 844  ssvWYHVSDAHVRQVSLDKVLH---SEAYILFYER 875
           567*******************...********98 PP

Organism

Brassica rapa

Protein Sequence
(Fasta)

MGKKAKKKAQ TKENLNQTKN LSEQPGEVAE EAVKEKQACV HLDKGLNLDK VLEKIKSSQV 60
IKCHECKEGA KAKGSNKGKH KAIWVCLECG CYVCGGVGLP TLPQSHVLKH IRSTRHRLVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAAGA AAGCTAAGAA GAAAGCTCAA ACTAAGGAGA ATCTGAATCA GACCAAGAAT 60
CTCTCCGAAC AGCCTGGTGA AGTAGCTGAG GAGGCAGTTA AGGAGAAGCA AGCTTGTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003015	Amborella trichopoda	32.03	3.00e-72	266.00
IUUC-Aly-005494	Arabidopsis lyrata	68.69	0.00e+00	1058.00
IUUC-Ath-007211	Arabidopsis thaliana	68.66	0.00e+00	1113.00
IUUC-Ame-011659	Astyanax mexicanus	34.04	6.00e-30	125.00
IUUC-Bol-015191	Brassica oleracea	88.23	0.00e+00	1396.00
IUUC-Dme-031870	Drosophila melanogaster	30.91	7.00e-15	76.30
IUUC-Gma-044402	Glycine max	44.52	1.00e-126	447.00
IUUC-Meu-055967	Macropus eugenii	26.60	4.00e-20	93.20
IUUC-Mtr-057945	Medicago truncatula	52.57	3.00e-86	313.00
IUUC-Mac-064941	Musa acuminata	34.10	1.00e-97	350.00
IUUC-Pop-099136	Populus trichocarpa	45.71	0.00e+00	645.00
IUUC-Ppe-101794	Prunus persica	44.34	4.00e-114	405.00
IUUC-Pva-102985	Pteropus vampyrus	32.78	2.00e-24	107.00
IUUC-Sit-110283	Setaria italica	31.35	3.00e-54	206.00
IUUC-Sly-111487	Solanum lycopersicum	40.67	4.00e-156	545.00
IUUC-Sbi-113785	Sorghum bicolor	30.23	2.00e-53	204.00
IUUC-Tsy-118869	Tarsius syrichta	32.64	9.00e-26	112.00
IUUC-Tca-121701	Theobroma cacao	44.73	1.00e-138	487.00
IUUC-Tur-126788	Triticum urartu	30.08	7.00e-50	192.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence