iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062641

UUCD1 version

UUC-MoD-00376

Ensembl Protein ID

ENSMODP00000021613.2

UniProt Accession

F6WX08; F6WX08_MONDO

Protein Name

Uncharacterized protein

Gene Name

FBXW5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000017319.3	ENSMODT00000021989.3	ENSMODP00000021613.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-15	56.8	521	551

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWD 29
           H+d v+++af   +  ll+s+sdD+tikvW+
   Q: 521  HEDVVNSVAFspLEqELLLSASDDNTIKVWR 551
           9*********9955699*************7 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MDDGGNPFLP DSIIYQIFLS LSHEDVLAAG LVCRQWQAVS RDEFLWKELF YRYYQVARDV 60
PRHPAAASWY EEFQRLYDTI PCVEVQTLRE HTDQVLHLSF SHTGYLFASC SKDCTVKIWN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAATCA TGGTTCGGGG CAGCGTGAGG CCTCAGCGCA AGCGCAGAAG GGGAGGAAGC 60
CGGGCACAGG AACCAGAACG ACTCGAGCCA GGGAAGGGGC GGTGGCGGCC GGGTGGAACG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0000151--C:ubiquitin ligase complex
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0010824--P:regulation of centrosome duplication
GO:0007088--P:regulation of mitotic nuclear division
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

KEGG

mdo:100022310

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001942	Ailuropoda melanoleuca	80.45	0.00e+00	933.00
IUUC-Apl-003274	Anas platyrhynchos	82.28	0.00e+00	826.00
IUUC-Aca-004626	Anolis carolinensis	57.63	5.00e-98	350.00
IUUC-Ame-011823	Astyanax mexicanus	63.35	0.00e+00	646.00
IUUC-Bta-012523	Bos taurus	80.80	0.00e+00	936.00
IUUC-Cja-018729	Callithrix jacchus	83.25	0.00e+00	976.00
IUUC-Cfa-020303	Canis familiaris	83.74	0.00e+00	971.00
IUUC-Cpo-022134	Cavia porcellus	82.01	0.00e+00	964.00
IUUC-Csa-023253	Chlorocebus sabaeus	83.74	0.00e+00	998.00
IUUC-Cin-025742	Ciona intestinalis	33.74	3.00e-82	299.00
IUUC-Dre-027511	Danio rerio	69.83	0.00e+00	761.00
IUUC-Dno-029044	Dasypus novemcinctus	82.35	0.00e+00	964.00
IUUC-Dor-030565	Dipodomys ordii	81.03	0.00e+00	949.00
IUUC-Dme-031713	Drosophila melanogaster	43.64	3.00e-133	469.00
IUUC-Eca-033709	Equus caballus	82.89	0.00e+00	938.00
IUUC-Eeu-035093	Erinaceus europaeus	86.74	1.00e-94	340.00
IUUC-Fca-035674	Felis catus	82.56	0.00e+00	962.00
IUUC-Fal-037104	Ficedula albicollis	77.72	0.00e+00	879.00
IUUC-Gmo-039041	Gadus morhua	64.25	0.00e+00	674.00
IUUC-Gga-041230	Gallus gallus	80.38	0.00e+00	950.00
IUUC-Gac-042594	Gasterosteus aculeatus	63.62	0.00e+00	685.00
IUUC-Ggo-044486	Gorilla gorilla	83.39	0.00e+00	962.00
IUUC-Hsa-045701	Homo sapiens	83.22	0.00e+00	962.00
IUUC-Itr-048811	Ictidomys tridecemlineatus	82.18	0.00e+00	978.00
IUUC-Lch-050058	Latimeria chalumnae	73.59	0.00e+00	886.00
IUUC-Loc-052525	Lepisosteus oculatus	71.86	0.00e+00	767.00
IUUC-Laf-054120	Loxodonta africana	81.87	0.00e+00	972.00
IUUC-Mcc-054915	Macaca mulatta	82.87	0.00e+00	970.00
IUUC-Meu-056715	Macropus eugenii	88.08	0.00e+00	1030.00
IUUC-Mga-059831	Meleagris gallopavo	80.99	0.00e+00	849.00
IUUC-Mmr-060655	Microcebus murinus	81.14	0.00e+00	962.00
IUUC-Mmu-063471	Mus musculus	80.38	0.00e+00	956.00
IUUC-Mpu-066586	Mustela putorius furo	83.39	0.00e+00	966.00
IUUC-Nle-069429	Nomascus leucogenys	83.22	0.00e+00	991.00
IUUC-Ont-071780	Oreochromis niloticus	69.04	0.00e+00	742.00
IUUC-Ola-086458	Oryzias latipes	67.33	0.00e+00	758.00
IUUC-Oga-088739	Otolemur garnettii	81.17	0.00e+00	972.00
IUUC-Oar-089275	Ovis aries	87.21	2.00e-44	169.00
IUUC-Ptr-090716	Pan troglodytes	81.76	0.00e+00	788.00
IUUC-Pan-092182	Papio anubis	75.61	0.00e+00	855.00
IUUC-Psi-093449	Pelodiscus sinensis	80.68	0.00e+00	947.00
IUUC-Pma-094289	Petromyzon marinus	53.20	1.00e-178	619.00
IUUC-Pfo-096062	Poecilia formosa	68.50	0.00e+00	749.00
IUUC-Pab-098726	Pongo abelii	81.66	0.00e+00	961.00
IUUC-Pca-100163	Procavia capensis	83.51	2.00e-92	332.00
IUUC-Pva-103051	Pteropus vampyrus	82.16	2.00e-130	459.00
IUUC-Rno-105707	Rattus norvegicus	81.14	0.00e+00	957.00
IUUC-Sha-107074	Sarcophilus harrisii	96.32	0.00e+00	1053.00
IUUC-Ssc-116020	Sus scrofa	79.68	0.00e+00	783.00
IUUC-Tgu-116683	Taeniopygia guttata	74.38	6.00e-106	376.00
IUUC-Tru-118143	Takifugu rubripes	68.17	0.00e+00	735.00
IUUC-Tni-120777	Tetraodon nigroviridis	67.94	0.00e+00	742.00
IUUC-Ttr-128439	Tursiops truncatus	79.41	0.00e+00	928.00
IUUC-Xtr-132774	Xenopus tropicalis	56.98	8.00e-154	536.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence