iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088540

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03079377

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000003024.2	ENSOGAT00000003027.2	ENSOGAP00000002708.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-41	138.8	508	540
UBD/Beta-Prp	5.30e-68	229.4	271	560

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHtd +t+l f +d +l++s+s D++++vWD+r
   Q: 508  GHTDNITSLTFsPDsGLIASASMDNSVRVWDIR 540
           8***********999****************76 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +sp+++lla+g+++++ik+w+++++kl                                ++ l gh ++v++++f  d++ l++
   Q: 271  LNTAEISPNSKLLAAGFDNSCIKLWSLRSKKLksephqvdvsrihlacdileeeddeddgagteMKILRGHCGPVYSTRFLADSSGLLS 359
           5667889********************************************************************************** PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdl +++ ++ ++gh + v++l++sp++ +++sGshdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++Gs+D
   Q: 360  CSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGSTD 447
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s+ fsp++ +++s+s+D+s+r
   Q: 448  KTVRLWSTQQGSSVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVR 535
           ******************9.********************************************************************* PP
   S: 248  iWdlrsgdllktlqlhnssvisvav 272
           +Wd+r+  +     ++ s ++ v +
   Q: 536  VWDIRNTYCSAPADGSSSELVGVYT 560
           **99998888877777744444444 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MKRVRTEQIQ MAVSCYLKRR QYMDSDGPLK QGLRLSQTAE EMAANLTVQS ESGCANIVSA 60
APCQAEPQQY EVQFGRLRNF LTDSDSQHSH EVMPLLYPLF VYLHLNLVQN SSKSTVESFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAACGAG TGCGCACCGA GCAGATTCAG ATGGCAGTGT CCTGCTACCT CAAACGCCGG 60
CAATACATGG ACTCCGATGG TCCCTTGAAG CAAGGGCTGC GGCTGTCACA GACTGCTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	97.28	0.00e+00	1099.00
IUUC-Apl-003636	Anas platyrhynchos	92.72	0.00e+00	1133.00
IUUC-Aca-004229	Anolis carolinensis	91.00	0.00e+00	1092.00
IUUC-Ame-010599	Astyanax mexicanus	67.05	0.00e+00	823.00
IUUC-Bta-013404	Bos taurus	92.53	0.00e+00	1046.00
IUUC-Cja-019643	Callithrix jacchus	98.13	0.00e+00	1132.00
IUUC-Cfa-020913	Canis familiaris	97.45	0.00e+00	1122.00
IUUC-Cpo-021777	Cavia porcellus	94.57	0.00e+00	1078.00
IUUC-Csa-024184	Chlorocebus sabaeus	98.13	0.00e+00	1133.00
IUUC-Cho-024638	Choloepus hoffmanni	96.77	0.00e+00	1091.00
IUUC-Cin-025618	Ciona intestinalis	34.96	1.00e-90	327.00
IUUC-Csv-025874	Ciona savignyi	34.38	2.00e-89	323.00
IUUC-Dre-028817	Danio rerio	67.11	0.00e+00	811.00
IUUC-Dno-029969	Dasypus novemcinctus	88.79	0.00e+00	1053.00
IUUC-Dor-031117	Dipodomys ordii	94.91	0.00e+00	1108.00
IUUC-Ete-032712	Echinops telfairi	89.47	0.00e+00	989.00
IUUC-Eca-033742	Equus caballus	97.45	0.00e+00	1121.00
IUUC-Eeu-035096	Erinaceus europaeus	94.58	0.00e+00	1121.00
IUUC-Fca-035769	Felis catus	96.45	0.00e+00	1137.00
IUUC-Fal-036645	Ficedula albicollis	92.45	0.00e+00	1069.00
IUUC-Fso-038302	Fusarium solani	33.98	5.00e-40	159.00
IUUC-Gmo-038636	Gadus morhua	64.33	0.00e+00	777.00
IUUC-Gga-040144	Gallus gallus	92.70	0.00e+00	1104.00
IUUC-Gac-041716	Gasterosteus aculeatus	68.06	0.00e+00	815.00
IUUC-Ggo-044568	Gorilla gorilla	98.30	0.00e+00	1134.00
IUUC-Hsa-046178	Homo sapiens	98.30	0.00e+00	1134.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	90.49	0.00e+00	1093.00
IUUC-Lch-050501	Latimeria chalumnae	77.84	0.00e+00	875.00
IUUC-Loc-052895	Lepisosteus oculatus	80.89	0.00e+00	642.00
IUUC-Laf-053950	Loxodonta africana	93.04	0.00e+00	1067.00
IUUC-Mcc-055450	Macaca mulatta	98.13	0.00e+00	1129.00
IUUC-Meu-056182	Macropus eugenii	88.62	0.00e+00	1019.00
IUUC-Mga-059619	Meleagris gallopavo	92.87	0.00e+00	1108.00
IUUC-Mmr-061074	Microcebus murinus	96.95	0.00e+00	1143.00
IUUC-Mdo-062307	Monodelphis domestica	93.54	0.00e+00	896.00
IUUC-Mmu-063226	Mus musculus	92.19	0.00e+00	1060.00
IUUC-Mpu-066016	Mustela putorius furo	96.94	0.00e+00	1094.00
IUUC-Mlu-067257	Myotis lucifugus	87.81	0.00e+00	1075.00
IUUC-Nle-070139	Nomascus leucogenys	98.13	0.00e+00	1131.00
IUUC-Opr-070243	Ochotona princeps	92.70	0.00e+00	1086.00
IUUC-Ont-072686	Oreochromis niloticus	68.83	0.00e+00	836.00
IUUC-Oan-073670	Ornithorhynchus anatinus	83.30	0.00e+00	850.00
IUUC-Ocu-074525	Oryctolagus cuniculus	97.28	0.00e+00	1133.00
IUUC-Ola-086524	Oryzias latipes	68.17	0.00e+00	854.00
IUUC-Oar-089793	Ovis aries	89.47	0.00e+00	979.00
IUUC-Ptr-091154	Pan troglodytes	98.30	0.00e+00	1134.00
IUUC-Pan-092759	Papio anubis	98.13	0.00e+00	1129.00
IUUC-Psi-094008	Pelodiscus sinensis	89.47	0.00e+00	1094.00
IUUC-Pma-094593	Petromyzon marinus	46.40	5.00e-134	471.00
IUUC-Pfo-097409	Poecilia formosa	67.22	0.00e+00	807.00
IUUC-Pab-097946	Pongo abelii	86.25	0.00e+00	976.00
IUUC-Pca-100727	Procavia capensis	89.13	0.00e+00	992.00
IUUC-Pva-103211	Pteropus vampyrus	84.21	0.00e+00	1008.00
IUUC-Ptt-103995	Puccinia triticina	43.21	1.00e-68	255.00
IUUC-Rno-105236	Rattus norvegicus	92.70	0.00e+00	1048.00
IUUC-Sha-106833	Sarcophilus harrisii	93.58	0.00e+00	1094.00
IUUC-Sar-113381	Sorex araneus	97.28	0.00e+00	1150.00
IUUC-Ssc-116421	Sus scrofa	94.74	0.00e+00	1134.00
IUUC-Tgu-117143	Taeniopygia guttata	92.70	0.00e+00	1133.00
IUUC-Tru-118680	Takifugu rubripes	68.17	0.00e+00	833.00
IUUC-Tsy-119622	Tarsius syrichta	82.00	0.00e+00	855.00
IUUC-Tni-120131	Tetraodon nigroviridis	67.67	0.00e+00	840.00
IUUC-Tbe-127656	Tupaia belangeri	95.45	4.00e-89	322.00
IUUC-Ttr-129171	Tursiops truncatus	94.40	0.00e+00	1070.00
IUUC-Xtr-132241	Xenopus tropicalis	81.19	0.00e+00	965.00
IUUC-Xma-133554	Xiphophorus maculatus	68.16	0.00e+00	751.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence