iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089332

Ensembl Protein ID

ENSOARP00000016323.1

UniProt Accession

W5Q0T7; W5Q0T7_SHEEP

Genbank Protein ID

ENSOARP00000016323

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AMGL01051265

Gene Name

BLK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000015215.1	ENSOART00000016559.1	ENSOARP00000016323.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.00e-14	54.4	56	113

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++ v +lydy+a+nd +L++ +G++++++   ++ ++W+ +++  +g++G +P+nFv+++e
   Q: 56   NHFVVALYDYKATNDRDLQMLRGEKLQIL---KETGDWWLAKSLITGREGYVPSNFVARVE 113
           57799************************...88899**********************97 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MGVVSSKRQV KEKGRSGWSP VKTSTQSKEP PPLPPLVVFN HLAPPPPDTT HPDQENHFVV 60
ALYDYKATND RDLQMLRGEK LQILKETGDW WLAKSLITGR EGYVPSNFVA RVETLEVEKW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTTTAC AAAACCCATG GAAAACCATC TTCATACACA CTGCTAAGGA AGTGAAGGAC 60
AAGGAAGCGT AAGTAGTGGT GATTTAATCT GAGGAATTGT ATTGATACTT CTTGTCAACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0050853--P:B cell receptor signaling pathway
GO:0032024--P:positive regulation of insulin secretion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002133	Ailuropoda melanoleuca	86.78	0.00e+00	841.00
IUUC-Apl-003307	Anas platyrhynchos	72.10	0.00e+00	693.00
IUUC-Bta-012400	Bos taurus	93.61	0.00e+00	926.00
IUUC-Cja-019717	Callithrix jacchus	83.37	0.00e+00	660.00
IUUC-Cfa-021056	Canis familiaris	85.43	0.00e+00	853.00
IUUC-Cpo-021779	Cavia porcellus	80.84	0.00e+00	822.00
IUUC-Csa-023557	Chlorocebus sabaeus	84.71	0.00e+00	823.00
IUUC-Eca-034218	Equus caballus	86.16	0.00e+00	828.00
IUUC-Eeu-035095	Erinaceus europaeus	63.87	2.00e-172	598.00
IUUC-Fca-036015	Felis catus	84.83	0.00e+00	852.00
IUUC-Fal-036946	Ficedula albicollis	71.46	0.00e+00	681.00
IUUC-Gga-040822	Gallus gallus	71.71	0.00e+00	691.00
IUUC-Ggo-044608	Gorilla gorilla	84.74	0.00e+00	762.00
IUUC-Hsa-046719	Homo sapiens	83.68	0.00e+00	812.00
IUUC-Itr-048323	Ictidomys tridecemlineatus	82.83	0.00e+00	824.00
IUUC-Laf-053387	Loxodonta africana	82.44	0.00e+00	825.00
IUUC-Mcc-055026	Macaca mulatta	84.50	0.00e+00	823.00
IUUC-Mga-059427	Meleagris gallopavo	71.05	0.00e+00	678.00
IUUC-Mmr-061660	Microcebus murinus	82.24	0.00e+00	827.00
IUUC-Mdo-062318	Monodelphis domestica	73.56	0.00e+00	738.00
IUUC-Mmu-063325	Mus musculus	82.04	0.00e+00	823.00
IUUC-Mpu-066582	Mustela putorius furo	85.83	0.00e+00	839.00
IUUC-Nle-069624	Nomascus leucogenys	84.68	0.00e+00	822.00
IUUC-Opr-070656	Ochotona princeps	77.25	0.00e+00	756.00
IUUC-Ocu-073907	Oryctolagus cuniculus	80.24	0.00e+00	816.00
IUUC-Oga-088057	Otolemur garnettii	82.04	0.00e+00	836.00
IUUC-Ptr-091551	Pan troglodytes	82.80	0.00e+00	779.00
IUUC-Pan-092173	Papio anubis	84.09	0.00e+00	820.00
IUUC-Psi-093895	Pelodiscus sinensis	70.54	0.00e+00	684.00
IUUC-Pab-097598	Pongo abelii	84.50	0.00e+00	808.00
IUUC-Pva-102135	Pteropus vampyrus	86.61	0.00e+00	819.00
IUUC-Rno-104891	Rattus norvegicus	80.44	0.00e+00	803.00
IUUC-Sha-107192	Sarcophilus harrisii	75.79	0.00e+00	758.00
IUUC-Ssc-115696	Sus scrofa	90.22	0.00e+00	893.00
IUUC-Tgu-117056	Taeniopygia guttata	71.40	0.00e+00	680.00
IUUC-Tbe-127520	Tupaia belangeri	88.42	0.00e+00	659.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence