iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088057

Ensembl Protein ID

ENSOGAP00000015643.1

UniProt Accession

H0XHQ3; H0XHQ3_OTOGA

Genbank Protein ID

ENSOGAP00000015643

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AAQR03106093

Gene Name

BLK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000026548.1	ENSOGAT00000032860.1	ENSOGAP00000015643.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-14	54.1	56	113

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++ v +lydy+a+nd +L++ kG++++v+   +  ++W+ +++  +g++G +P+nFv+++e
   Q: 56   EHFVVALYDYTAVNDRDLQMLKGEKLQVL---KGTGDWWLAKSLVTGREGYVPSNFVARVE 113
           57799************************...999************************97 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MGLVSSKKQV KEKGKGRWSP SKVSTPSKTL PTRPAMVLFG HLTPPPPEED CPDEEEHFVV 60
ALYDYTAVND RDLQMLKGEK LQVLKGTGDW WLAKSLVTGR EGYVPSNFVA RVESLEVEKW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGACTGG TGAGCAGCAA GAAGCAGGTG AAGGAGAAGG GCAAGGGCCG ATGGAGCCCG 60
TCGAAGGTCA GCACCCCAAG CAAGACGCCC CCACCACTGC CACCCCTGGT GAGTGATCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0050853--P:B cell receptor signaling pathway
GO:0032024--P:positive regulation of insulin secretion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002133	Ailuropoda melanoleuca	88.82	0.00e+00	894.00
IUUC-Apl-003307	Anas platyrhynchos	76.63	0.00e+00	738.00
IUUC-Aca-004357	Anolis carolinensis	69.89	0.00e+00	675.00
IUUC-Ame-010642	Astyanax mexicanus	71.01	0.00e+00	683.00
IUUC-Bta-012400	Bos taurus	87.43	0.00e+00	906.00
IUUC-Cja-019717	Callithrix jacchus	84.37	0.00e+00	684.00
IUUC-Cfa-021056	Canis familiaris	88.22	0.00e+00	909.00
IUUC-Cpo-021779	Cavia porcellus	84.83	0.00e+00	867.00
IUUC-Csa-023557	Chlorocebus sabaeus	88.93	0.00e+00	900.00
IUUC-Dre-027517	Danio rerio	71.62	0.00e+00	688.00
IUUC-Eca-034218	Equus caballus	88.02	0.00e+00	877.00
IUUC-Eeu-035095	Erinaceus europaeus	66.07	0.00e+00	651.00
IUUC-Fca-036015	Felis catus	87.82	0.00e+00	905.00
IUUC-Fal-036946	Ficedula albicollis	76.18	0.00e+00	732.00
IUUC-Gmo-038861	Gadus morhua	65.99	3.00e-179	620.00
IUUC-Gga-040822	Gallus gallus	76.18	0.00e+00	738.00
IUUC-Ggo-044608	Gorilla gorilla	93.16	0.00e+00	840.00
IUUC-Hsa-046719	Homo sapiens	88.14	0.00e+00	897.00
IUUC-Itr-048323	Ictidomys tridecemlineatus	89.02	0.00e+00	904.00
IUUC-Lch-050114	Latimeria chalumnae	72.20	0.00e+00	695.00
IUUC-Loc-052326	Lepisosteus oculatus	73.09	0.00e+00	701.00
IUUC-Laf-053387	Loxodonta africana	86.03	0.00e+00	890.00
IUUC-Mcc-055026	Macaca mulatta	88.93	0.00e+00	897.00
IUUC-Mga-059427	Meleagris gallopavo	75.56	0.00e+00	728.00
IUUC-Mmr-061660	Microcebus murinus	90.82	0.00e+00	926.00
IUUC-Mdo-062318	Monodelphis domestica	75.35	0.00e+00	791.00
IUUC-Mmu-063325	Mus musculus	86.03	0.00e+00	883.00
IUUC-Mpu-066582	Mustela putorius furo	88.82	0.00e+00	893.00
IUUC-Nle-069624	Nomascus leucogenys	90.89	0.00e+00	896.00
IUUC-Opr-070656	Ochotona princeps	81.64	0.00e+00	812.00
IUUC-Ont-072266	Oreochromis niloticus	64.73	0.00e+00	674.00
IUUC-Ocu-073907	Oryctolagus cuniculus	85.03	0.00e+00	876.00
IUUC-Ola-086668	Oryzias latipes	70.50	0.00e+00	663.00
IUUC-Oar-089332	Ovis aries	82.04	0.00e+00	843.00
IUUC-Ptr-091551	Pan troglodytes	86.86	0.00e+00	857.00
IUUC-Pan-092173	Papio anubis	88.54	0.00e+00	895.00
IUUC-Psi-093895	Pelodiscus sinensis	75.11	0.00e+00	731.00
IUUC-Pfo-096608	Poecilia formosa	70.18	0.00e+00	682.00
IUUC-Pab-097598	Pongo abelii	88.14	0.00e+00	887.00
IUUC-Pva-102135	Pteropus vampyrus	91.69	0.00e+00	861.00
IUUC-Rno-104891	Rattus norvegicus	85.03	0.00e+00	861.00
IUUC-Sha-107192	Sarcophilus harrisii	76.79	0.00e+00	803.00
IUUC-Ssc-115696	Sus scrofa	88.02	0.00e+00	907.00
IUUC-Tgu-117056	Taeniopygia guttata	75.90	0.00e+00	729.00
IUUC-Tru-117621	Takifugu rubripes	69.20	0.00e+00	658.00
IUUC-Tbe-127520	Tupaia belangeri	86.84	0.00e+00	670.00
IUUC-Ttr-128457	Tursiops truncatus	87.82	0.00e+00	905.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence