iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007534

UUCD1 version

UUC-ArT-01593

Ensembl Protein ID

AT1G63800.1

UniProt Accession

P42749; Q4TZ04; Q8VXY5; Q9CAE2; Q9CAJ4; UBC5_ARATH

Genbank Protein ID

AAA32902.1; AAY44846.1; AAG52444.1; AAG52422.1; AEE34149.1; AAL67043.1; AAM45109.1; BAF02237.1

Protein Name

Ubiquitin-conjugating enzyme E2 5; E2 ubiquitin-conjugating enzyme 5; Ubiquitin carrier protein 5; Ubiquitin-conjugating enzyme E2-21 kDa 2; Ubiquitin-protein ligase 5

Genbank Nucleotide ID

L19356; DQ027020; AC010852; AC011622; CP002684; AY074347; AY114061; AK230439

Gene Name

UBC5; At1g63800; F24D7.1; T12P18.18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT1G63800	AT1G63800.1	AT1G63800.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
PINA	HINT
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	16339806

Classification

Family	E-value	Score	Start	End
E2/UBC	2.60e-34	118.8	11	141

Active Site

Position(s)	Description	Evidence
85	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 8    elekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkeeekWspalsvesvl.l 103
           +l+k  ++ +++++ ++  ++e+ v++ Gp+d++Yeggv+k+++e+p+ YP+k+P+v f+tki+hPnv+e  G+vCl++++  ++Wsp+ ++ +v+ +
   Q: 11   DLMKLMMSDYKVEMIND-GMQEFFVEFSGPKDSIYEGGVWKIRVELPDAYPYKSPSVGFITKIYHPNVDEMsGSVCLDVIN--QTWSPMFDLVNVFeT 105
           56677788899999999.7***************************************************99********9..*************78 PP
   S: 104  siqsllaepnpesplneeaaellkknreeykkkvre 139
            + +ll  pnp++pln eaa l+ ++r +y+++v+e
   Q: 106  FLPQLLLYPNPSDPLNGEAAALMMRDRPTYEQRVKE 141
           899******************************985 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Protein Sequence
(Fasta)

MSSPSKRREM DLMKLMMSDY KVEMINDGMQ EFFVEFSGPK DSIYEGGVWK IRVELPDAYP 60
YKSPSVGFIT KIYHPNVDEM SGSVCLDVIN QTWSPMFDLV NVFETFLPQL LLYPNPSDPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATATCTGTA ATAAAATAAA ACAAAATAAT GAAAAAGATT CTCTCACATT ATCTTATTTC 60
TCCACTTGAT TCCCAGAAGA CAAAAAAAAA AAAAATCAGA AAAAAAGAAG AAGAGAGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005829--C:cytosol
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ath:AT1G63800

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001260	Ailuropoda melanoleuca	60.29	2.00e-47	180.00
IUUC-Atr-002681	Amborella trichopoda	87.25	5.00e-77	279.00
IUUC-Apl-003547	Anas platyrhynchos	62.83	2.00e-43	167.00
IUUC-Aca-005224	Anolis carolinensis	62.93	5.00e-43	166.00
IUUC-Aly-005836	Arabidopsis lyrata	98.38	2.00e-91	327.00
IUUC-Ago-007727	Ashbya gossypii	59.18	1.00e-52	198.00
IUUC-Acl-008119	Aspergillus clavatus	61.27	1.00e-61	228.00
IUUC-Afl-008412	Aspergillus flavus	71.30	1.00e-47	181.00
IUUC-Afu-008925	Aspergillus fumigatus	57.69	3.00e-57	213.00
IUUC-Ani-009294	Aspergillus nidulans	57.22	1.00e-57	214.00
IUUC-Ang-009805	Aspergillus niger	64.24	7.00e-62	228.00
IUUC-Aor-010201	Aspergillus oryzae	60.78	3.00e-53	200.00
IUUC-Ate-010441	Aspergillus terreus	59.73	7.00e-50	188.00
IUUC-Ame-010807	Astyanax mexicanus	53.70	3.00e-33	133.00
IUUC-Bta-012802	Bos taurus	60.29	2.00e-47	180.00
IUUC-Bdi-014713	Brachypodium distachyon	91.95	5.00e-82	295.00
IUUC-Bol-016385	Brassica oleracea	87.63	2.00e-85	306.00
IUUC-Cel-018412	Caenorhabditis elegans	51.27	2.00e-49	187.00
IUUC-Cja-019571	Callithrix jacchus	44.90	3.00e-33	133.00
IUUC-Cfa-020811	Canis familiaris	60.29	2.00e-47	180.00
IUUC-Cpo-021889	Cavia porcellus	62.93	1.00e-43	168.00
IUUC-Cre-022956	Chlamydomonas reinhardtii	62.18	8.00e-68	248.00
IUUC-Csa-023289	Chlorocebus sabaeus	60.29	2.00e-47	180.00
IUUC-Cin-025571	Ciona intestinalis	41.77	1.00e-28	118.00
IUUC-Cgl-026627	Colletotrichum gloeosporioides	62.35	5.00e-57	212.00
IUUC-Cme-027171	Cyanidioschyzon merolae	69.13	1.00e-63	235.00
IUUC-Dre-027450	Danio rerio	60.29	2.00e-47	180.00
IUUC-Dno-029838	Dasypus novemcinctus	60.29	2.00e-47	180.00
IUUC-Dor-031119	Dipodomys ordii	60.29	2.00e-47	180.00
IUUC-Dse-031243	Dothistroma septosporum	61.17	8.00e-65	238.00
IUUC-Dme-031807	Drosophila melanogaster	56.67	7.00e-50	189.00
IUUC-Ete-032437	Echinops telfairi	57.00	5.00e-32	129.00
IUUC-Eca-034123	Equus caballus	60.80	2.00e-45	174.00
IUUC-Fca-035502	Felis catus	60.29	2.00e-47	180.00
IUUC-Fal-037054	Ficedula albicollis	62.93	2.00e-43	167.00
IUUC-Fso-038148	Fusarium solani	60.54	4.00e-53	199.00
IUUC-Gmo-038858	Gadus morhua	55.70	3.00e-51	193.00
IUUC-Ggr-039749	Gaeumannomyces graminis	61.82	9.00e-56	208.00
IUUC-Gga-040942	Gallus gallus	60.29	2.00e-47	180.00
IUUC-Gac-042079	Gasterosteus aculeatus	56.33	9.00e-53	198.00
IUUC-Gma-044272	Glycine max	92.62	5.00e-82	295.00
IUUC-Hsa-046545	Homo sapiens	60.29	2.00e-47	180.00
IUUC-Hvu-047260	Hordeum vulgare	87.16	1.00e-77	281.00
IUUC-Itr-048474	Ictidomys tridecemlineatus	60.29	2.00e-47	180.00
IUUC-Kpa-049144	Komagataella pastoris	74.42	2.00e-57	214.00
IUUC-Lch-050589	Latimeria chalumnae	59.85	5.00e-45	172.00
IUUC-Lpe-051335	Leersia perrieri	91.95	3.00e-82	296.00
IUUC-Loc-052829	Lepisosteus oculatus	60.29	4.00e-47	179.00
IUUC-Laf-053526	Loxodonta africana	61.03	5.00e-47	179.00
IUUC-Mcc-055611	Macaca mulatta	60.29	2.00e-47	180.00
IUUC-Mor-057278	Magnaporthe oryzae	58.86	8.00e-55	205.00
IUUC-Mpo-057484	Magnaporthe poae	64.58	1.00e-51	194.00
IUUC-Mtr-058579	Medicago truncatula	79.46	4.00e-82	296.00
IUUC-Mla-058926	Melampsora laricipopulina	68.71	6.00e-63	232.00
IUUC-Mga-059801	Meleagris gallopavo	60.29	2.00e-47	180.00
IUUC-Mvi-060244	Microbotryum violaceum	68.87	5.00e-65	239.00
IUUC-Mmr-061205	Microcebus murinus	60.29	2.00e-47	180.00
IUUC-Mmu-063974	Mus musculus	60.29	2.00e-47	180.00
IUUC-Mac-065395	Musa acuminata	88.59	3.00e-80	289.00
IUUC-Mpu-066759	Mustela putorius furo	60.29	2.00e-47	180.00
IUUC-Mlu-067674	Myotis lucifugus	62.93	1.00e-43	168.00
IUUC-Nfi-068618	Neosartorya fischeri	64.00	6.00e-56	209.00
IUUC-Ncr-068712	Neurospora crassa	69.17	7.00e-54	201.00
IUUC-Nle-069926	Nomascus leucogenys	60.29	2.00e-47	180.00
IUUC-Opr-070598	Ochotona princeps	60.29	2.00e-47	180.00
IUUC-Ont-071893	Oreochromis niloticus	57.14	8.00e-52	195.00
IUUC-Oan-073273	Ornithorhynchus anatinus	62.93	1.00e-43	168.00
IUUC-Ocu-074357	Oryctolagus cuniculus	60.29	5.00e-47	179.00
IUUC-Oba-075055	Oryza barthii	91.95	3.00e-82	296.00
IUUC-Obr-076538	Oryza brachyantha	91.28	6.00e-82	295.00
IUUC-Ogl-077784	Oryza glaberrima	91.95	3.00e-82	296.00
IUUC-Ogu-078045	Oryza glumaepatula	91.95	3.00e-82	296.00
IUUC-Oin-079163	Oryza indica	91.95	3.00e-82	296.00
IUUC-Olo-080847	Oryza longistaminata	82.64	1.00e-68	251.00
IUUC-Ome-081586	Oryza meridionalis	84.47	5.00e-79	286.00
IUUC-Oni-082913	Oryza nivara	91.95	3.00e-82	296.00
IUUC-Opu-083651	Oryza punctata	91.95	3.00e-82	296.00
IUUC-Oru-084980	Oryza rufipogon	91.95	3.00e-82	296.00
IUUC-Osa-085334	Oryza sativa	91.43	2.00e-76	276.00
IUUC-Ola-087423	Oryzias latipes	56.33	4.00e-52	196.00
IUUC-Oga-088412	Otolemur garnettii	60.29	2.00e-47	180.00
IUUC-Oar-090282	Ovis aries	62.93	1.00e-43	167.00
IUUC-Ptr-090470	Pan troglodytes	60.29	2.00e-47	180.00
IUUC-Pan-092552	Papio anubis	60.29	2.00e-47	180.00
IUUC-Psi-093516	Pelodiscus sinensis	59.84	8.00e-44	168.00
IUUC-Pno-094800	Phaeosphaeria nodorum	56.85	8.00e-49	185.00
IUUC-Ppa-095962	Physcomitrella patens	84.46	6.00e-76	275.00
IUUC-Pfo-097374	Poecilia formosa	60.29	2.00e-47	181.00
IUUC-Pab-098112	Pongo abelii	60.29	2.00e-47	180.00
IUUC-Pva-102776	Pteropus vampyrus	61.76	6.00e-47	179.00
IUUC-Pgr-103325	Puccinia graminis	69.63	2.00e-58	217.00
IUUC-Pte-104024	Pyrenophora teres	60.12	2.00e-60	224.00
IUUC-Pyt-104715	Pyrenophora triticirepentis	68.94	7.00e-58	215.00
IUUC-Rno-105699	Rattus norvegicus	59.56	8.00e-47	179.00
IUUC-Sce-106165	Saccharomyces cerevisiae	63.85	2.00e-49	188.00
IUUC-Sha-106524	Sarcophilus harrisii	62.93	1.00e-43	167.00
IUUC-Spo-108105	Schizosaccharomyces pombe	64.86	5.00e-61	226.00
IUUC-Ssl-108543	Sclerotinia sclerotiorum	61.44	3.00e-54	203.00
IUUC-Smo-108956	Selaginella moellendorffii	73.26	1.00e-78	284.00
IUUC-Sit-110211	Setaria italica	92.62	7.00e-83	299.00
IUUC-Sly-111921	Solanum lycopersicum	91.89	4.00e-80	289.00
IUUC-Stu-112525	Solanum tuberosum	92.57	2.00e-80	290.00
IUUC-Sar-113572	Sorex araneus	43.97	1.00e-22	98.60
IUUC-Sbi-114111	Sorghum bicolor	92.62	2.00e-82	297.00
IUUC-Sre-115027	Sporisorium reilianum	68.21	2.00e-64	237.00
IUUC-Ssc-116221	Sus scrofa	60.00	2.00e-43	167.00
IUUC-Tgu-116965	Taeniopygia guttata	62.93	1.00e-43	167.00
IUUC-Tru-117574	Takifugu rubripes	59.56	9.00e-47	178.00
IUUC-Tni-120422	Tetraodon nigroviridis	59.56	8.00e-47	178.00
IUUC-Tca-121070	Theobroma cacao	92.62	3.00e-81	293.00
IUUC-Tre-122110	Trichoderma reesei	57.74	1.00e-56	211.00
IUUC-Tvi-122592	Trichoderma virens	59.86	5.00e-52	196.00
IUUC-Tae-125866	Triticum aestivum	91.95	5.00e-82	295.00
IUUC-Tme-127020	Tuber melanosporum	61.65	1.00e-45	174.00
IUUC-Ttr-128734	Tursiops truncatus	60.29	2.00e-47	180.00
IUUC-Uma-129334	Ustilago maydis	68.21	2.00e-64	237.00
IUUC-Vda-129953	Verticillium dahliae	61.21	5.00e-59	219.00
IUUC-Vpa-130729	Vicugna pacos	62.93	1.00e-43	167.00
IUUC-Vvi-131712	Vitis vinifera	81.91	2.00e-81	293.00
IUUC-Xtr-132368	Xenopus tropicalis	60.29	2.00e-47	181.00
IUUC-Xma-133864	Xiphophorus maculatus	60.29	2.00e-47	181.00
IUUC-Zma-135047	Zea mays	92.62	6.00e-82	295.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence