iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069300

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01172569

Gene Name

KLHL40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000005861.1	ENSNLET00000007441.1	ENSNLEP00000007089.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.10e-14	54.5	34	97
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.00e-08	32.5	130	161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           D+++  g++ef++h++vLaa+S++F+a fl e e     ++ ++++v+p+v+ ++l++lYt+++ ++
   Q: 34   DCVVRAGEREFPCHRLVLAACSPYFRARFLAEPERA---GELHLEEVSPDVVAQVLHYLYTSEIALD 97
           99999************************9988864...69*********************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           l+Ncl+++r++ l+dc +L+ aa+dfi+ hF+
   Q: 130  LSNCLAVFRLGLLLDCARLAVAARDFICAHFT 161
           79*****************************7 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MALGLEQAEE QRLYQQTLLQ DGLKDMLDHG KFLDCVVRAG EREFPCHRLV LAACSPYFRA 60
RFLAEPERAG ELHLEEVSPD VVAQVLHYLY TSEIALDEAS VQDLFAAAHR FQIPSIFTIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCTGG GCTTGGAGCA GGCGGAGGAG CAGCGGTTGT ACCAGCAGAC ACTCCTGCAA 60
GACGGGCTCA AAGACATGCT GGACCATGGC AAGTTCCTCG ACTGTGTGGT GCGGGCGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR030607--KLHL40
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB

SMART

SM00875--BACK
SM00225--BTB

Gene Ontology

GO:0031397--P:negative regulation of protein ubiquitination
GO:0048741--P:skeletal muscle fiber development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001792	Ailuropoda melanoleuca	88.89	0.00e+00	711.00
IUUC-Acl-008133	Aspergillus clavatus	33.87	3.00e-04	40.00
IUUC-Bta-012801	Bos taurus	90.48	0.00e+00	783.00
IUUC-Cja-019795	Callithrix jacchus	93.84	0.00e+00	759.00
IUUC-Cfa-021245	Canis familiaris	89.62	0.00e+00	785.00
IUUC-Cpo-022436	Cavia porcellus	88.58	0.00e+00	781.00
IUUC-Csa-023105	Chlorocebus sabaeus	98.40	0.00e+00	824.00
IUUC-Dno-030015	Dasypus novemcinctus	85.19	0.00e+00	628.00
IUUC-Eca-034393	Equus caballus	89.50	0.00e+00	744.00
IUUC-Fca-035823	Felis catus	83.88	0.00e+00	687.00
IUUC-Ggo-045596	Gorilla gorilla	99.32	0.00e+00	824.00
IUUC-Hsa-046235	Homo sapiens	99.32	0.00e+00	823.00
IUUC-Itr-048612	Ictidomys tridecemlineatus	93.41	0.00e+00	800.00
IUUC-Laf-053485	Loxodonta africana	88.57	0.00e+00	722.00
IUUC-Mcc-054909	Macaca mulatta	98.86	0.00e+00	824.00
IUUC-Mmr-060736	Microcebus murinus	95.66	0.00e+00	808.00
IUUC-Mdo-062563	Monodelphis domestica	75.57	0.00e+00	674.00
IUUC-Mmu-063549	Mus musculus	89.27	0.00e+00	772.00
IUUC-Mpu-066262	Mustela putorius furo	89.57	0.00e+00	784.00
IUUC-Mlu-067210	Myotis lucifugus	91.14	0.00e+00	770.00
IUUC-Opr-070384	Ochotona princeps	85.26	0.00e+00	695.00
IUUC-Ocu-074499	Oryctolagus cuniculus	91.22	0.00e+00	791.00
IUUC-Oga-088855	Otolemur garnettii	94.06	0.00e+00	801.00
IUUC-Oar-089342	Ovis aries	76.71	6.00e-176	610.00
IUUC-Ptr-091028	Pan troglodytes	99.31	0.00e+00	821.00
IUUC-Pan-091827	Papio anubis	98.86	0.00e+00	824.00
IUUC-Pab-097656	Pongo abelii	98.92	0.00e+00	679.00
IUUC-Pva-102331	Pteropus vampyrus	89.80	0.00e+00	785.00
IUUC-Pte-104085	Pyrenophora teres	33.82	2.00e-04	40.00
IUUC-Pyt-104655	Pyrenophora triticirepentis	33.82	2.00e-04	40.00
IUUC-Rno-105613	Rattus norvegicus	88.36	0.00e+00	760.00
IUUC-Sar-112941	Sorex araneus	85.84	3.00e-171	594.00
IUUC-Ssc-116276	Sus scrofa	90.02	0.00e+00	789.00
IUUC-Tsy-119499	Tarsius syrichta	93.68	0.00e+00	662.00
IUUC-Tbe-127806	Tupaia belangeri	92.26	0.00e+00	786.00
IUUC-Ttr-128813	Tursiops truncatus	89.77	0.00e+00	777.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence