iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092666

Ensembl Protein ID

ENSPANP00000008426.1

UniProt Accession

A0A096N7C5; A0A096N7C5_PAPAN

Genbank Protein ID

ENSPANP00000008426

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01026573

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000019659.1	ENSPANT00000025539.1	ENSPANP00000008426.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.30e-14	53.2	166	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            v++ ++++ +n+deL+  kGd+++v     +++gW++g  +l+g+ G fP+n+v++++
   Q: 166  IVKARFNFKQTNEDELSVCKGDIIYVT--RVEEGGWWEG--TLNGRTGWFPSNYVREIK 220
           68999*********************7..999*******..8**************997 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MNPEEQIVTW LISLGVLDSP KKTICDPEEF LKSSLKNGVV LCKLINRLMP GSVEKFCKGP 60
DSSEKCINYI NNFKDKKHCI KLQAQVFDPD DLYSGVNFCK VLSTLLAVNK ATEDQLSERP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATCCAG AAGAACAAAT CGTGACATGG CTTATATCTT TGGGAGTTTT AGATTCCCCT 60
AAAAAGACCA TCTGTGATCC GGAGGAGTTT TTAAAGTCCT CGCTGAAAAA TGGGGTGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	77.43	0.00e+00	1215.00
IUUC-Apl-003960	Anas platyrhynchos	73.52	0.00e+00	1080.00
IUUC-Aca-004988	Anolis carolinensis	68.72	0.00e+00	1007.00
IUUC-Aly-005591	Arabidopsis lyrata	38.71	7.00e-09	54.70
IUUC-Ame-011546	Astyanax mexicanus	61.81	0.00e+00	916.00
IUUC-Bta-013527	Bos taurus	92.16	0.00e+00	1360.00
IUUC-Cja-018935	Callithrix jacchus	95.50	0.00e+00	1401.00
IUUC-Cfa-021269	Canis familiaris	91.65	0.00e+00	1347.00
IUUC-Cpo-021620	Cavia porcellus	86.21	0.00e+00	1261.00
IUUC-Csa-023415	Chlorocebus sabaeus	97.30	0.00e+00	1425.00
IUUC-Cin-025535	Ciona intestinalis	42.86	2.00e-82	300.00
IUUC-Cne-026866	Cryptococcus neoformans	52.94	2.00e-12	68.60
IUUC-Dre-028580	Danio rerio	62.06	0.00e+00	927.00
IUUC-Dno-029201	Dasypus novemcinctus	87.87	0.00e+00	1326.00
IUUC-Dor-030868	Dipodomys ordii	73.78	0.00e+00	993.00
IUUC-Dme-032219	Drosophila melanogaster	43.72	1.00e-95	345.00
IUUC-Eca-033500	Equus caballus	92.16	0.00e+00	1340.00
IUUC-Eeu-035269	Erinaceus europaeus	77.14	1.00e-153	536.00
IUUC-Fca-035683	Felis catus	91.52	0.00e+00	1319.00
IUUC-Fal-037611	Ficedula albicollis	73.78	0.00e+00	1080.00
IUUC-Gmo-038980	Gadus morhua	59.92	0.00e+00	887.00
IUUC-Gga-040940	Gallus gallus	72.59	0.00e+00	1077.00
IUUC-Gac-042203	Gasterosteus aculeatus	58.82	0.00e+00	904.00
IUUC-Ggo-044755	Gorilla gorilla	96.53	0.00e+00	1415.00
IUUC-Hsa-046210	Homo sapiens	96.02	0.00e+00	1410.00
IUUC-Lch-049517	Latimeria chalumnae	67.65	0.00e+00	1005.00
IUUC-Loc-052393	Lepisosteus oculatus	62.55	0.00e+00	975.00
IUUC-Laf-054196	Loxodonta africana	90.09	0.00e+00	1284.00
IUUC-Mcc-055716	Macaca mulatta	97.43	0.00e+00	1426.00
IUUC-Meu-056285	Macropus eugenii	68.97	0.00e+00	635.00
IUUC-Mtr-058576	Medicago truncatula	44.62	4.00e-11	62.00
IUUC-Mga-060029	Meleagris gallopavo	73.26	0.00e+00	1096.00
IUUC-Mmr-060803	Microcebus murinus	92.42	0.00e+00	1350.00
IUUC-Mdo-062654	Monodelphis domestica	76.92	0.00e+00	1166.00
IUUC-Mmu-063479	Mus musculus	88.67	0.00e+00	1275.00
IUUC-Mpu-066065	Mustela putorius furo	90.87	0.00e+00	1311.00
IUUC-Mlu-068222	Myotis lucifugus	90.89	0.00e+00	1307.00
IUUC-Nle-069379	Nomascus leucogenys	96.53	0.00e+00	1415.00
IUUC-Opr-070687	Ochotona princeps	71.43	0.00e+00	793.00
IUUC-Ont-072240	Oreochromis niloticus	57.28	0.00e+00	877.00
IUUC-Oan-073067	Ornithorhynchus anatinus	78.92	0.00e+00	1176.00
IUUC-Ocu-074852	Oryctolagus cuniculus	91.65	0.00e+00	1331.00
IUUC-Oga-089048	Otolemur garnettii	85.55	0.00e+00	1159.00
IUUC-Oar-089339	Ovis aries	92.16	0.00e+00	1355.00
IUUC-Psi-093116	Pelodiscus sinensis	73.56	0.00e+00	1119.00
IUUC-Pfo-097394	Poecilia formosa	60.96	0.00e+00	899.00
IUUC-Pab-098567	Pongo abelii	96.53	0.00e+00	1417.00
IUUC-Pca-100997	Procavia capensis	76.99	0.00e+00	1066.00
IUUC-Pva-102500	Pteropus vampyrus	89.97	0.00e+00	1284.00
IUUC-Rno-104974	Rattus norvegicus	88.93	0.00e+00	1258.00
IUUC-Sar-113420	Sorex araneus	86.12	0.00e+00	1236.00
IUUC-Ssc-115679	Sus scrofa	94.08	0.00e+00	1229.00
IUUC-Tgu-117069	Taeniopygia guttata	73.26	0.00e+00	1080.00
IUUC-Tru-118488	Takifugu rubripes	54.95	0.00e+00	790.00
IUUC-Tsy-119243	Tarsius syrichta	87.18	0.00e+00	952.00
IUUC-Tni-120584	Tetraodon nigroviridis	58.90	0.00e+00	886.00
IUUC-Tbe-127994	Tupaia belangeri	76.74	0.00e+00	1088.00
IUUC-Ttr-128839	Tursiops truncatus	90.36	0.00e+00	1290.00
IUUC-Vpa-130144	Vicugna pacos	83.16	0.00e+00	1148.00
IUUC-Xtr-132624	Xenopus tropicalis	69.99	0.00e+00	1047.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence