iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000012638.1	ENSOART00000013742.1	ENSOARP00000013542.1
ENSOARG00000012638.1	ENSOART00000013746.1	ENSOARP00000013546.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.90e-12	46.8	1155	1202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           + C+vC+++ged+ +l+ C++C+++fH  Cl ++   e+p+ e w Cp C+
   Q: 1155 ARCKVCRKKGEDD-KLILCDECNKAFHLFCLRPA-LYEVPDGE-WQCPACQ 1202
           57*********98.6*******************.*******8.******7 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

AHREYEARLE RYSERIWTCK STGSSQLTHK EAWEEEQEVA ELLKEEFPAW YEKLVLEMVH 60
HNTASLEKLV DTAWLEIMTK YAVGEECDFE VGKEKMLKVR IVKIHPLEKV DEEATEKKSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGTGCGCG GGCGGGCCGG CCAGCCGGCC GGGGCCAGGC CGCCTCCGAG CCTTGAGCCC 60
TCCATCCTTC CCCTGGCTCC GCACTTTGTC CCCGGGCCTC GTTATGGAGG AGCGACCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR018501--DDT_dom
IPR009071--HMG_box_dom
IPR028942--WHIM1_dom
IPR028941--WHIM2_dom
IPR013136--WSTF_Acf1_Cbp146
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50827--DDT
PS51136--WAC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF10537--WAC_Acf1_DNA_bd
PF15612--WHIM1
PF15613--WSD

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00571--DDT
SM00249--PHD

Gene Ontology

GO:0000793--C:condensed chromosome
GO:0016604--C:nuclear body
GO:0043596--C:nuclear replication fork
GO:0005721--C:pericentric heterochromatin
GO:0003682--F:chromatin binding
GO:0035173--F:histone kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0071884--F:vitamin D receptor activator activity
GO:0008270--F:zinc ion binding
GO:0006333--P:chromatin assembly or disassembly
GO:0048096--P:chromatin-mediated maintenance of transcription
GO:0006302--P:double-strand break repair
GO:0003007--P:heart morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002113	Ailuropoda melanoleuca	93.82	0.00e+00	2417.00
IUUC-Apl-003454	Anas platyrhynchos	78.65	0.00e+00	2114.00
IUUC-Ame-011469	Astyanax mexicanus	62.62	0.00e+00	1239.00
IUUC-Bta-012408	Bos taurus	96.83	0.00e+00	2463.00
IUUC-Cja-019194	Callithrix jacchus	92.64	0.00e+00	2429.00
IUUC-Cfa-021083	Canis familiaris	93.69	0.00e+00	2425.00
IUUC-Cpo-021422	Cavia porcellus	90.85	0.00e+00	2311.00
IUUC-Csa-023848	Chlorocebus sabaeus	92.98	0.00e+00	2437.00
IUUC-Dre-027895	Danio rerio	61.60	0.00e+00	1258.00
IUUC-Dno-029686	Dasypus novemcinctus	92.18	0.00e+00	2393.00
IUUC-Dor-030625	Dipodomys ordii	79.06	0.00e+00	1266.00
IUUC-Ete-032702	Echinops telfairi	93.68	0.00e+00	1031.00
IUUC-Eca-033647	Equus caballus	94.50	0.00e+00	2480.00
IUUC-Eeu-034626	Erinaceus europaeus	87.13	0.00e+00	2012.00
IUUC-Fca-036092	Felis catus	93.38	0.00e+00	2068.00
IUUC-Fal-037127	Ficedula albicollis	77.82	0.00e+00	2068.00
IUUC-Gmo-039455	Gadus morhua	56.98	0.00e+00	1362.00
IUUC-Gga-041120	Gallus gallus	78.31	0.00e+00	2000.00
IUUC-Gac-041873	Gasterosteus aculeatus	60.93	0.00e+00	1272.00
IUUC-Ggo-045317	Gorilla gorilla	93.00	0.00e+00	2448.00
IUUC-Hsa-046773	Homo sapiens	93.05	0.00e+00	2419.00
IUUC-Itr-049026	Ictidomys tridecemlineatus	91.67	0.00e+00	2379.00
IUUC-Lch-050271	Latimeria chalumnae	69.49	0.00e+00	1646.00
IUUC-Loc-052699	Lepisosteus oculatus	64.99	0.00e+00	1016.00
IUUC-Mcc-055171	Macaca mulatta	92.92	0.00e+00	2434.00
IUUC-Meu-055990	Macropus eugenii	82.76	0.00e+00	1972.00
IUUC-Mga-059913	Meleagris gallopavo	77.97	0.00e+00	1955.00
IUUC-Mmr-061681	Microcebus murinus	94.01	0.00e+00	2427.00
IUUC-Mdo-062486	Monodelphis domestica	84.63	0.00e+00	2113.00
IUUC-Mmu-063460	Mus musculus	87.78	0.00e+00	2161.00
IUUC-Mpu-066324	Mustela putorius furo	96.15	0.00e+00	1308.00
IUUC-Mlu-067334	Myotis lucifugus	93.26	0.00e+00	2466.00
IUUC-Nle-069983	Nomascus leucogenys	92.85	0.00e+00	2462.00
IUUC-Opr-070678	Ochotona princeps	78.34	0.00e+00	746.00
IUUC-Ont-071565	Oreochromis niloticus	59.54	0.00e+00	962.00
IUUC-Ocu-074779	Oryctolagus cuniculus	91.76	0.00e+00	2368.00
IUUC-Ola-086746	Oryzias latipes	59.02	0.00e+00	1305.00
IUUC-Oga-088475	Otolemur garnettii	90.03	0.00e+00	2317.00
IUUC-Ptr-090963	Pan troglodytes	92.85	0.00e+00	2409.00
IUUC-Pan-091819	Papio anubis	92.03	0.00e+00	1952.00
IUUC-Psi-093967	Pelodiscus sinensis	80.36	0.00e+00	1955.00
IUUC-Pfo-096939	Poecilia formosa	56.47	0.00e+00	1335.00
IUUC-Pab-098679	Pongo abelii	92.34	0.00e+00	2248.00
IUUC-Pop-099061	Populus trichocarpa	65.52	5.00e-09	55.10
IUUC-Pva-102969	Pteropus vampyrus	95.77	0.00e+00	2256.00
IUUC-Rno-104927	Rattus norvegicus	88.59	0.00e+00	2198.00
IUUC-Sha-107021	Sarcophilus harrisii	82.55	0.00e+00	2021.00
IUUC-Ssc-116243	Sus scrofa	94.09	0.00e+00	2431.00
IUUC-Tgu-117073	Taeniopygia guttata	75.42	0.00e+00	1779.00
IUUC-Tru-118265	Takifugu rubripes	57.76	0.00e+00	1315.00
IUUC-Ttr-128885	Tursiops truncatus	91.76	0.00e+00	2057.00
IUUC-Vvi-131714	Vitis vinifera	50.00	2.00e-12	66.60
IUUC-Xtr-131812	Xenopus tropicalis	67.73	0.00e+00	1368.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence