iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090027

Ensembl Protein ID

ENSOARP00000009606.1

UniProt Accession

W5PGP0; W5PGP0_SHEEP

Genbank Protein ID

ENSOARP00000009606

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01115352

Gene Name

KDM5C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000008936.1	ENSOART00000009744.1	ENSOARP00000009606.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.40e-13	51.0	326	372

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vC +C +g+ed+ +l+ C+ C++++H  Cl ++  +e p+   w CpkC 
   Q: 326  VCRMCSRGDEDD-KLLLCDGCDDNYHIFCLLPP-LPEIPKGV-WRCPKCV 372
           8*********88.6*******************.*******8.******6 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MEPGSDDFLP PPECPVFEPS WAEFRDPLGY IAKIRPIAEK SGICKIRPPA DWQPPFAVEV 60
DNFRFTPRIQ RLNELEAQTR VKLNYLDQIA KFWEIQGSSL KIPNVERRIL DLYSLSKIVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGCCGG GGTCTGACGA CTTTCTACCG CCGCCGGAGT GCCCGGTGTT CGAGCCTAGC 60
TGGGCGGAGT TCCGAGACCC TCTTGGCTAC ATTGCGAAAA TCAGGCCCAT CGCCGAGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0003677--F:DNA binding
GO:0032453--F:histone demethylase activity (H3-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0008270--F:zinc ion binding
GO:0045892--P:negative regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001327	Ailuropoda melanoleuca	97.49	0.00e+00	2647.00
IUUC-Aca-004712	Anolis carolinensis	79.97	0.00e+00	1981.00
IUUC-Afl-008625	Aspergillus flavus	30.32	2.00e-112	401.00
IUUC-Afu-008796	Aspergillus fumigatus	31.46	4.00e-116	413.00
IUUC-Ani-009139	Aspergillus nidulans	31.17	4.00e-109	390.00
IUUC-Aor-010155	Aspergillus oryzae	30.32	2.00e-112	401.00
IUUC-Bta-013099	Bos taurus	99.81	0.00e+00	2656.00
IUUC-Bci-013992	Botrytis cinerea	29.54	1.00e-106	381.00
IUUC-Cja-018723	Callithrix jacchus	93.50	0.00e+00	2528.00
IUUC-Cfa-020954	Canis familiaris	98.45	0.00e+00	2595.00
IUUC-Cpo-021718	Cavia porcellus	98.25	0.00e+00	1374.00
IUUC-Csa-023946	Chlorocebus sabaeus	97.91	0.00e+00	2592.00
IUUC-Dre-028238	Danio rerio	63.12	0.00e+00	1834.00
IUUC-Dno-029435	Dasypus novemcinctus	98.25	0.00e+00	2574.00
IUUC-Dor-030226	Dipodomys ordii	90.39	0.00e+00	1803.00
IUUC-Dse-031479	Dothistroma septosporum	29.30	4.00e-118	420.00
IUUC-Eca-033834	Equus caballus	96.26	0.00e+00	2690.00
IUUC-Eeu-034692	Erinaceus europaeus	95.28	0.00e+00	2010.00
IUUC-Fca-035766	Felis catus	95.62	0.00e+00	2512.00
IUUC-Fox-037694	Fusarium oxysporum	31.87	3.00e-100	360.00
IUUC-Fso-038127	Fusarium solani	30.67	2.00e-116	414.00
IUUC-Gmo-039140	Gadus morhua	71.07	0.00e+00	1681.00
IUUC-Gac-041825	Gasterosteus aculeatus	64.32	0.00e+00	1780.00
IUUC-Ggo-045492	Gorilla gorilla	97.36	0.00e+00	2677.00
IUUC-Hsa-046737	Homo sapiens	97.16	0.00e+00	2657.00
IUUC-Itr-048348	Ictidomys tridecemlineatus	96.91	0.00e+00	2685.00
IUUC-Lch-050517	Latimeria chalumnae	75.15	0.00e+00	2085.00
IUUC-Laf-054098	Loxodonta africana	88.65	0.00e+00	2345.00
IUUC-Mcc-055740	Macaca mulatta	96.97	0.00e+00	2666.00
IUUC-Meu-056643	Macropus eugenii	84.86	0.00e+00	2262.00
IUUC-Mtr-058113	Medicago truncatula	32.78	1.00e-96	348.00
IUUC-Mmr-061032	Microcebus murinus	97.57	0.00e+00	2582.00
IUUC-Mdo-062754	Monodelphis domestica	81.40	0.00e+00	2195.00
IUUC-Mmu-063943	Mus musculus	93.87	0.00e+00	2625.00
IUUC-Mpu-066800	Mustela putorius furo	97.93	0.00e+00	2670.00
IUUC-Mlu-067109	Myotis lucifugus	97.09	0.00e+00	2628.00
IUUC-Nfi-068430	Neosartorya fischeri	31.36	9.00e-113	402.00
IUUC-Ncr-068763	Neurospora crassa	29.25	9.00e-111	395.00
IUUC-Nle-069569	Nomascus leucogenys	98.68	0.00e+00	2573.00
IUUC-Ont-072274	Oreochromis niloticus	65.16	0.00e+00	1826.00
IUUC-Oan-073160	Ornithorhynchus anatinus	85.64	0.00e+00	2261.00
IUUC-Ocu-074440	Oryctolagus cuniculus	96.97	0.00e+00	2622.00
IUUC-Oin-079273	Oryza indica	37.84	1.00e-13	69.30
IUUC-Ola-087059	Oryzias latipes	65.84	0.00e+00	1856.00
IUUC-Oga-088191	Otolemur garnettii	96.76	0.00e+00	2655.00
IUUC-Ptr-091415	Pan troglodytes	84.49	0.00e+00	2372.00
IUUC-Pan-091829	Papio anubis	97.29	0.00e+00	2667.00
IUUC-Pma-094137	Petromyzon marinus	56.30	0.00e+00	1288.00
IUUC-Pfo-096645	Poecilia formosa	65.42	0.00e+00	1791.00
IUUC-Pab-097582	Pongo abelii	95.44	0.00e+00	2351.00
IUUC-Pca-100446	Procavia capensis	92.65	0.00e+00	2558.00
IUUC-Ppe-101504	Prunus persica	32.56	2.00e-102	368.00
IUUC-Pva-102553	Pteropus vampyrus	94.28	0.00e+00	1639.00
IUUC-Pgr-103434	Puccinia graminis	35.98	2.00e-29	122.00
IUUC-Rno-105359	Rattus norvegicus	79.91	0.00e+00	2298.00
IUUC-Sha-106769	Sarcophilus harrisii	88.37	0.00e+00	2128.00
IUUC-Sja-107970	Schizosaccharomyces japonicus	21.65	4.00e-40	160.00
IUUC-Ssl-108489	Sclerotinia sclerotiorum	30.50	6.00e-117	416.00
IUUC-Sre-115161	Sporisorium reilianum	30.60	3.00e-133	470.00
IUUC-Ssc-116354	Sus scrofa	97.94	0.00e+00	2721.00
IUUC-Tru-117667	Takifugu rubripes	65.50	0.00e+00	1654.00
IUUC-Tni-119920	Tetraodon nigroviridis	64.68	0.00e+00	1771.00
IUUC-Tca-121478	Theobroma cacao	32.40	5.00e-106	379.00
IUUC-Tbe-128040	Tupaia belangeri	99.64	0.00e+00	1088.00
IUUC-Ttr-128979	Tursiops truncatus	96.97	0.00e+00	2672.00
IUUC-Uma-129590	Ustilago maydis	29.89	9.00e-131	462.00
IUUC-Vpa-130433	Vicugna pacos	99.26	0.00e+00	1806.00
IUUC-Vvi-131071	Vitis vinifera	32.27	3.00e-85	310.00
IUUC-Xtr-132324	Xenopus tropicalis	68.75	0.00e+00	1907.00
IUUC-Xma-134315	Xiphophorus maculatus	64.56	0.00e+00	1840.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence