iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072323

Ensembl Protein ID

ENSONIP00000019499.1

UniProt Accession

I3KEF4; I3KEF4_ORENI

Genbank Protein ID

ENSONIP00000019499

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01067621

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000015497.1	ENSONIT00000019516.1	ENSONIP00000019499.1
ENSONIG00000015497.1	ENSONIT00000019517.1	ENSONIP00000019500.1
ENSONIG00000015497.1	ENSONIT00000019518.1	ENSONIP00000019501.1
ENSONIG00000015497.1	ENSONIT00000019519.1	ENSONIP00000019502.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.80e-07	31.4	373	412

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd  ++ pCgH+++++Cl +w    ++s ++  CP Cr
   Q: 373  CKICAENDKD-IKIEPCGHLMCTSCLTAW----QESDGQ-GCPFCR 412
           99********.******************....555555.5****8 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MATALSSRYP GGRGPNRSKG RILGIIDAIQ DAVGPPKQAV ADRRTVEKTW KLMDKVVRLC 60
QNPRLQLKNS PPYILDILPD AYQHLRVILG KYEENQMIIQ LSENDYFNIY IDSLMKKSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTAACTTCA CACCTGTTTT GCCGTACAAA ACGTATTGTG CCTCGCGATT ATACAGTTCC 60
TCCGGCTGCT CCCAGGGAGT TGCTCTTATT TGACAATTAT AAATTTTGAG GATTTATAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001412	Ailuropoda melanoleuca	84.54	0.00e+00	890.00
IUUC-Apl-004148	Anas platyrhynchos	83.46	0.00e+00	886.00
IUUC-Aca-005204	Anolis carolinensis	69.72	0.00e+00	866.00
IUUC-Ame-011919	Astyanax mexicanus	69.26	0.00e+00	917.00
IUUC-Bta-013044	Bos taurus	84.54	0.00e+00	889.00
IUUC-Cja-018813	Callithrix jacchus	83.95	0.00e+00	867.00
IUUC-Cfa-021054	Canis familiaris	71.16	0.00e+00	894.00
IUUC-Cpo-022514	Cavia porcellus	67.57	0.00e+00	892.00
IUUC-Csa-024110	Chlorocebus sabaeus	84.35	0.00e+00	885.00
IUUC-Cho-024886	Choloepus hoffmanni	67.08	4.00e-167	582.00
IUUC-Dre-027480	Danio rerio	70.16	0.00e+00	934.00
IUUC-Dno-028923	Dasypus novemcinctus	84.92	0.00e+00	867.00
IUUC-Dor-031040	Dipodomys ordii	78.79	0.00e+00	714.00
IUUC-Ete-032406	Echinops telfairi	68.01	0.00e+00	803.00
IUUC-Eca-033849	Equus caballus	84.73	0.00e+00	891.00
IUUC-Fca-036224	Felis catus	84.54	0.00e+00	890.00
IUUC-Fal-036860	Ficedula albicollis	82.84	0.00e+00	870.00
IUUC-Gga-040159	Gallus gallus	73.42	0.00e+00	901.00
IUUC-Gac-042312	Gasterosteus aculeatus	87.68	0.00e+00	939.00
IUUC-Ggo-045175	Gorilla gorilla	84.63	0.00e+00	874.00
IUUC-Hsa-046306	Homo sapiens	84.35	0.00e+00	885.00
IUUC-Loc-052524	Lepisosteus oculatus	74.49	0.00e+00	926.00
IUUC-Laf-053635	Loxodonta africana	78.48	0.00e+00	811.00
IUUC-Mcc-055536	Macaca mulatta	84.35	0.00e+00	885.00
IUUC-Meu-056045	Macropus eugenii	69.08	0.00e+00	677.00
IUUC-Mga-060177	Meleagris gallopavo	73.15	0.00e+00	813.00
IUUC-Mmr-061088	Microcebus murinus	84.35	0.00e+00	886.00
IUUC-Mdo-062020	Monodelphis domestica	69.23	0.00e+00	885.00
IUUC-Mmu-063114	Mus musculus	70.60	0.00e+00	887.00
IUUC-Mpu-066632	Mustela putorius furo	84.54	0.00e+00	889.00
IUUC-Mlu-067145	Myotis lucifugus	84.35	0.00e+00	888.00
IUUC-Oan-073165	Ornithorhynchus anatinus	69.37	0.00e+00	894.00
IUUC-Ocu-074723	Oryctolagus cuniculus	84.35	0.00e+00	885.00
IUUC-Oga-088021	Otolemur garnettii	84.54	0.00e+00	887.00
IUUC-Oar-089809	Ovis aries	84.35	0.00e+00	886.00
IUUC-Ptr-090834	Pan troglodytes	84.35	0.00e+00	885.00
IUUC-Pan-092225	Papio anubis	84.35	0.00e+00	887.00
IUUC-Psi-093317	Pelodiscus sinensis	70.05	0.00e+00	896.00
IUUC-Pab-097595	Pongo abelii	84.35	0.00e+00	885.00
IUUC-Pca-100844	Procavia capensis	70.04	0.00e+00	682.00
IUUC-Pva-103216	Pteropus vampyrus	84.41	0.00e+00	872.00
IUUC-Rno-105381	Rattus norvegicus	70.92	0.00e+00	891.00
IUUC-Sha-107574	Sarcophilus harrisii	69.64	0.00e+00	890.00
IUUC-Tgu-116866	Taeniopygia guttata	73.64	0.00e+00	889.00
IUUC-Tru-118579	Takifugu rubripes	81.09	0.00e+00	1005.00
IUUC-Tsy-119167	Tarsius syrichta	73.28	0.00e+00	726.00
IUUC-Tni-120788	Tetraodon nigroviridis	91.30	0.00e+00	975.00
IUUC-Tbe-127830	Tupaia belangeri	79.39	0.00e+00	814.00
IUUC-Ttr-128631	Tursiops truncatus	84.54	0.00e+00	889.00
IUUC-Vpa-130713	Vicugna pacos	70.74	0.00e+00	880.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence