iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025574

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

EAAA01000435

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000002655.3	ENSCINT00000005403.3	ENSCINP00000005403.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.40e-08	34.9	379	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e  kd +++ pCgH+++++Cl+ w+ +    s + +CP+Cr
   Q: 379  CKICAENNKD-VRIEPCGHLICKSCLESWQEM--DNSASPTCPWCR 421
           99********.******************444..4888889****8 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MASGAMNGNT AQQRHAQRQG PIRILNHFRG FSDALNDVTP HHQRVTIDKK YIEKSSKLMD 60
KVAKFCQQSK MNLKNSPPYI LDILPDTYNH LRLIMLRYED RLQVLNECEY FRIFLDNLIK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCAAATATA GGAAAATCAT AAGATCATAT TTAGTGTTTG TGTAAATCTG TATAATCAGC 60
ATGGCAAGTG GGGCAATGAA TGGGAACACA GCTCAGCAGA GGCATGCACA AAGACAGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0045121--C:membrane raft
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0030971--F:receptor tyrosine kinase binding
GO:0017124--F:SH3 domain binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0006508--P:proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001412	Ailuropoda melanoleuca	67.89	1.00e-172	598.00
IUUC-Apl-004148	Anas platyrhynchos	68.38	3.00e-173	600.00
IUUC-Aca-005204	Anolis carolinensis	68.63	9.00e-174	602.00
IUUC-Ame-011919	Astyanax mexicanus	65.70	2.00e-165	574.00
IUUC-Bta-012759	Bos taurus	71.54	2.00e-177	614.00
IUUC-Cel-018674	Caenorhabditis elegans	55.56	1.00e-127	448.00
IUUC-Cja-019207	Callithrix jacchus	71.54	1.00e-177	615.00
IUUC-Cfa-020897	Canis familiaris	71.65	1.00e-176	612.00
IUUC-Cpo-022514	Cavia porcellus	67.89	6.00e-172	596.00
IUUC-Csa-023136	Chlorocebus sabaeus	71.54	1.00e-177	615.00
IUUC-Cho-024282	Choloepus hoffmanni	59.74	7.00e-139	486.00
IUUC-Csv-025938	Ciona savignyi	94.44	0.00e+00	785.00
IUUC-Dre-027644	Danio rerio	70.48	1.00e-177	615.00
IUUC-Dno-028923	Dasypus novemcinctus	68.14	1.00e-172	598.00
IUUC-Dor-031040	Dipodomys ordii	58.09	5.00e-139	487.00
IUUC-Dme-032213	Drosophila melanogaster	69.97	2.00e-174	604.00
IUUC-Ete-032406	Echinops telfairi	69.87	5.00e-164	570.00
IUUC-Eca-033849	Equus caballus	67.89	2.00e-172	598.00
IUUC-Eeu-035142	Erinaceus europaeus	60.70	6.00e-138	483.00
IUUC-Fca-035455	Felis catus	71.54	2.00e-177	614.00
IUUC-Fal-037182	Ficedula albicollis	71.03	3.00e-176	610.00
IUUC-Gmo-038698	Gadus morhua	69.97	3.00e-175	607.00
IUUC-Gga-040438	Gallus gallus	71.03	8.00e-177	612.00
IUUC-Gac-042166	Gasterosteus aculeatus	70.74	1.00e-176	612.00
IUUC-Ggo-045618	Gorilla gorilla	71.54	2.00e-177	614.00
IUUC-Hsa-046177	Homo sapiens	71.54	2.00e-177	615.00
IUUC-Itr-048795	Ictidomys tridecemlineatus	74.33	7.00e-140	489.00
IUUC-Lch-050095	Latimeria chalumnae	70.99	2.00e-177	614.00
IUUC-Loc-052570	Lepisosteus oculatus	71.28	1.00e-178	619.00
IUUC-Lma-053133	Leptosphaeria maculans	25.71	1.00e-05	41.60
IUUC-Laf-054008	Loxodonta africana	71.54	2.00e-176	611.00
IUUC-Mcc-054676	Macaca mulatta	71.54	1.00e-177	615.00
IUUC-Meu-056045	Macropus eugenii	53.68	9.00e-126	443.00
IUUC-Mga-059239	Meleagris gallopavo	71.03	5.00e-177	613.00
IUUC-Mmr-060907	Microcebus murinus	71.54	1.00e-177	615.00
IUUC-Mdo-062020	Monodelphis domestica	67.89	2.00e-172	598.00
IUUC-Mmu-063725	Mus musculus	71.28	3.00e-178	617.00
IUUC-Mpu-066771	Mustela putorius furo	71.28	3.00e-177	614.00
IUUC-Mlu-067145	Myotis lucifugus	67.89	1.00e-172	598.00
IUUC-Nle-069285	Nomascus leucogenys	71.54	6.00e-177	613.00
IUUC-Opr-071026	Ochotona princeps	71.66	2.00e-171	594.00
IUUC-Ont-071954	Oreochromis niloticus	70.74	1.00e-177	615.00
IUUC-Oan-073165	Ornithorhynchus anatinus	67.89	5.00e-173	600.00
IUUC-Ocu-074723	Oryctolagus cuniculus	67.89	2.00e-172	598.00
IUUC-Obr-076362	Oryza brachyantha	40.00	4.00e-06	43.10
IUUC-Opu-083619	Oryza punctata	38.30	8.00e-06	42.70
IUUC-Ola-087165	Oryzias latipes	70.48	3.00e-177	614.00
IUUC-Oga-088198	Otolemur garnettii	71.54	8.00e-177	612.00
IUUC-Oar-089809	Ovis aries	68.14	3.00e-173	600.00
IUUC-Ptr-090710	Pan troglodytes	71.54	2.00e-177	615.00
IUUC-Pan-092785	Papio anubis	71.54	1.00e-177	615.00
IUUC-Psi-093317	Pelodiscus sinensis	67.40	6.00e-173	600.00
IUUC-Pma-094249	Petromyzon marinus	67.05	1.00e-105	374.00
IUUC-Pno-094793	Phaeosphaeria nodorum	45.65	3.00e-06	46.20
IUUC-Pfo-096049	Poecilia formosa	69.57	2.00e-174	605.00
IUUC-Pab-098526	Pongo abelii	71.54	2.00e-177	615.00
IUUC-Pca-100844	Procavia capensis	54.66	2.00e-122	432.00
IUUC-Pva-102352	Pteropus vampyrus	71.54	8.00e-174	602.00
IUUC-Pte-104031	Pyrenophora teres	47.83	5.00e-07	47.40
IUUC-Pyt-104791	Pyrenophora triticirepentis	45.65	1.00e-06	46.20
IUUC-Rno-105876	Rattus norvegicus	71.28	6.00e-178	616.00
IUUC-Sha-107574	Sarcophilus harrisii	67.89	1.00e-172	598.00
IUUC-Sar-112959	Sorex araneus	71.66	7.00e-172	596.00
IUUC-Ssc-115261	Sus scrofa	71.54	3.00e-177	614.00
IUUC-Tgu-116580	Taeniopygia guttata	71.03	6.00e-177	613.00
IUUC-Tru-118731	Takifugu rubripes	70.99	2.00e-178	617.00
IUUC-Tsy-119167	Tarsius syrichta	71.01	2.00e-133	468.00
IUUC-Tni-120725	Tetraodon nigroviridis	70.92	8.00e-174	602.00
IUUC-Tbe-128018	Tupaia belangeri	71.66	3.00e-171	594.00
IUUC-Ttr-128927	Tursiops truncatus	71.54	9.00e-178	615.00
IUUC-Vpa-130713	Vicugna pacos	67.89	4.00e-172	597.00
IUUC-Xtr-132474	Xenopus tropicalis	70.32	5.00e-179	620.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence