iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012449

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

F-box only protein 4

Genbank Nucleotide ID

DAAA02050534

Gene Name

FBXO4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000016981.4	ENSBTAT00000022583.4	ENSBTAP00000022583.4

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	90.44	0.00e+00	686.00	IUUC-Hsa-046558

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Protein Sequence
(Fasta)

MAGSDPGSRG SSPQPPHSDW GRLEAAFLSG RRNFWQSVGK ERAAPRASAE EVDEEASSLT 60
RLPIDVQLYI LSFLSPHDLC QLGSTSRYWN ETVRDPILWR YFLLRDLPSW SSVDWKSLPD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAGGCGTA GGCAGCCATG GCGGGAAGCG ACCCTGGCAG CCGAGGGAGC TCTCCTCAGC 60
CTCCTCACAG CGACTGGGGC CGCCTGGAGG CGGCCTTCCT CAGCGGCTCG GAGGAACTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom

PROSITE

PS50181--FBOX

Pfam

PF00646--F-box

SMART

SM00256--FBOX

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0007568--P:aging
GO:0019725--P:cellular homeostasis
GO:0071479--P:cellular response to ionizing radiation
GO:0035726--P:common myeloid progenitor cell proliferation
GO:0048147--P:negative regulation of fibroblast proliferation
GO:1900181--P:negative regulation of protein localization to nucleus
GO:1902916--P:positive regulation of protein polyubiquitination
GO:0010608--P:posttranscriptional regulation of gene expression
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:2000001--P:regulation of DNA damage checkpoint
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001232	Ailuropoda melanoleuca	96.21	0.00e+00	717.00
IUUC-Apl-004129	Anas platyrhynchos	62.76	7.00e-110	389.00
IUUC-Aca-005076	Anolis carolinensis	50.79	4.00e-111	394.00
IUUC-Aly-006351	Arabidopsis lyrata	30.77	7.00e-04	38.10
IUUC-Ath-007114	Arabidopsis thaliana	35.19	1.00e-03	37.40
IUUC-Ame-011122	Astyanax mexicanus	47.98	2.00e-87	315.00
IUUC-Bci-013771	Botrytis cinerea	29.82	3.00e-03	36.60
IUUC-Bol-015278	Brassica oleracea	24.19	7.00e-06	45.10
IUUC-Bra-017713	Brassica rapa	40.35	4.00e-05	41.60
IUUC-Cja-019890	Callithrix jacchus	89.92	0.00e+00	701.00
IUUC-Cfa-021134	Canis familiaris	93.80	0.00e+00	712.00
IUUC-Cpo-021693	Cavia porcellus	89.81	2.00e-169	587.00
IUUC-Csa-023540	Chlorocebus sabaeus	90.70	0.00e+00	693.00
IUUC-Dre-028667	Danio rerio	48.18	5.00e-88	317.00
IUUC-Dno-028997	Dasypus novemcinctus	92.08	0.00e+00	685.00
IUUC-Dor-030135	Dipodomys ordii	80.00	1.00e-153	535.00
IUUC-Ete-033149	Echinops telfairi	85.98	0.00e+00	654.00
IUUC-Eca-033292	Equus caballus	95.99	0.00e+00	631.00
IUUC-Eeu-034504	Erinaceus europaeus	74.07	5.00e-130	457.00
IUUC-Fca-036476	Felis catus	94.57	0.00e+00	761.00
IUUC-Fal-036711	Ficedula albicollis	64.26	1.00e-121	429.00
IUUC-Gmo-039592	Gadus morhua	49.24	6.00e-90	323.00
IUUC-Gga-040924	Gallus gallus	64.00	2.00e-125	441.00
IUUC-Gac-041791	Gasterosteus aculeatus	49.56	5.00e-87	314.00
IUUC-Ggo-044736	Gorilla gorilla	89.92	0.00e+00	686.00
IUUC-Hsa-046558	Homo sapiens	90.44	0.00e+00	690.00
IUUC-Itr-048956	Ictidomys tridecemlineatus	89.41	0.00e+00	671.00
IUUC-Lch-049817	Latimeria chalumnae	65.75	1.00e-128	452.00
IUUC-Loc-052226	Lepisosteus oculatus	51.23	7.00e-106	377.00
IUUC-Laf-054371	Loxodonta africana	91.73	0.00e+00	690.00
IUUC-Mcc-054904	Macaca mulatta	90.44	0.00e+00	692.00
IUUC-Meu-056192	Macropus eugenii	57.72	5.00e-94	337.00
IUUC-Mmr-061692	Microcebus murinus	88.89	0.00e+00	693.00
IUUC-Mdo-062666	Monodelphis domestica	77.60	3.00e-163	567.00
IUUC-Mmu-064223	Mus musculus	86.30	0.00e+00	701.00
IUUC-Mpu-066290	Mustela putorius furo	95.87	0.00e+00	717.00
IUUC-Mlu-067882	Myotis lucifugus	91.21	0.00e+00	710.00
IUUC-Nle-070162	Nomascus leucogenys	90.44	0.00e+00	691.00
IUUC-Opr-070789	Ochotona princeps	88.36	8.00e-77	280.00
IUUC-Ont-071690	Oreochromis niloticus	47.71	3.00e-81	295.00
IUUC-Oan-072928	Ornithorhynchus anatinus	74.23	6.00e-114	403.00
IUUC-Ocu-073857	Oryctolagus cuniculus	91.33	0.00e+00	646.00
IUUC-Oni-083091	Oryza nivara	32.26	1.00e+00	30.00
IUUC-Oru-085096	Oryza rufipogon	32.26	1.00e+00	30.00
IUUC-Osa-086253	Oryza sativa	35.42	2.50e-01	30.00
IUUC-Ola-086607	Oryzias latipes	47.15	5.00e-88	317.00
IUUC-Oga-088929	Otolemur garnettii	91.53	0.00e+00	658.00
IUUC-Oar-089305	Ovis aries	98.77	0.00e+00	649.00
IUUC-Ptr-090813	Pan troglodytes	85.79	0.00e+00	654.00
IUUC-Pan-092924	Papio anubis	89.20	9.00e-180	622.00
IUUC-Psi-093237	Pelodiscus sinensis	66.57	2.00e-130	458.00
IUUC-Pfo-096259	Poecilia formosa	47.16	2.00e-88	319.00
IUUC-Pab-098292	Pongo abelii	90.96	0.00e+00	695.00
IUUC-Pva-102221	Pteropus vampyrus	94.57	0.00e+00	735.00
IUUC-Rno-105910	Rattus norvegicus	88.11	0.00e+00	710.00
IUUC-Sha-106998	Sarcophilus harrisii	76.03	2.00e-165	575.00
IUUC-Sar-113033	Sorex araneus	81.91	4.00e-179	620.00
IUUC-Ssc-115507	Sus scrofa	94.32	0.00e+00	679.00
IUUC-Tgu-116502	Taeniopygia guttata	64.16	5.00e-119	420.00
IUUC-Tru-118203	Takifugu rubripes	45.48	7.00e-76	277.00
IUUC-Tni-120249	Tetraodon nigroviridis	44.65	3.00e-77	281.00
IUUC-Tur-126361	Triticum urartu	30.36	3.00e-04	38.90
IUUC-Tbe-128100	Tupaia belangeri	66.76	8.00e-120	423.00
IUUC-Ttr-128299	Tursiops truncatus	84.24	0.00e+00	647.00
IUUC-Vpa-130394	Vicugna pacos	84.50	5.00e-175	607.00
IUUC-Xtr-131825	Xenopus tropicalis	55.06	1.00e-122	432.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence